Obese state leads to elevated levels of TGF-β and COX isoforms in platelets of Zucker rats

Molecular and Cellular Biochemistry

Volumn 284, Issue 1-2, 2006, Pages 19-24

  Raju, Jayadev ^a   Bajaj, Gagan ^b   Chrusch, Jennifer ^b   Bird, Ranjana P ^a,b  

^a UNIVERSITY OF WATERLOO   (Canada)

^b UNIVERSITY OF MANITOBA   (Canada)

Author keywords

Colon cancer; COX; Energy restriction; Hyperinsulinemia; Obesity; Platelet; TGF ; Zucker rats

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; ISOPROTEIN; PROSTAGLANDIN SYNTHASE; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2; ISOENZYME; MEMBRANE PROTEIN; PTGS1 PROTEIN, RAT; PTGS2 PROTEIN, RAT; TGFB1 PROTEIN, RAT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOCHEMICAL COMPOSITION; CALORIC INTAKE; CELL ISOLATION; CHRONIC DISEASE; COLON CANCER; COLON CARCINOGENESIS; CONTROLLED STUDY; FEMALE; GENOTYPE; NONHUMAN; OBESITY; PATHOGENESIS; PRECANCER; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; RAT STRAIN; STATISTICAL SIGNIFICANCE; THROMBOCYTE FUNCTION; WESTERN BLOTTING; ANIMAL; BLOOD; COLON TUMOR; ENZYMOLOGY; LOW CARBOHYDRATE DIET; METABOLISM; THROMBOCYTE; ZUCKER RAT;

ANIMALIA;

ANIMALS; BLOOD PLATELETS; COLONIC NEOPLASMS; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; DIET, CARBOHYDRATE-RESTRICTED; ENERGY INTAKE; FEMALE; ISOENZYMES; MEMBRANE PROTEINS; OBESITY; PRECANCEROUS CONDITIONS; RATS; RATS, ZUCKER; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA2;

EID: 33745919816     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-005-9008-3     Document Type: Article

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