Bilateral lesions of the gustatory thalamus disrupt morphine- but not LiCl-induced intake suppression in rats: Evidence against the conditioned taste aversion hypothesis

Brain Research

Volumn 858, Issue 2, 2000, Pages 327-337

  Grigson, Patricia Sue ^a   Lyuboslavsky, Polina ^a   Tanase, Diana ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Anticipatory contrast; Conditioned taste aversion; Gustatory thalamus; LiCl; Morphine; VPMpc

Indexed keywords

LITHIUM CHLORIDE; MORPHINE; SACCHARIN;

ANIMAL MODEL; ANIMAL TISSUE; ANTICIPATION; ARTICLE; BRAIN INJURY; CONDITIONING; CONTROLLED STUDY; DRUG USE; GUSTATORY NERVOUS SYSTEM; HYPOTHESIS; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; TASTE AVERSION;

ANIMALS; ANTIMANIC AGENTS; AVOIDANCE LEARNING; CONDITIONING (PSYCHOLOGY); DENERVATION; DRINKING; EXCITATORY AMINO ACID AGONISTS; IBOTENIC ACID; LITHIUM CHLORIDE; MALE; MORPHINE; NARCOTICS; RATS; RATS, SPRAGUE-DAWLEY; SACCHARIN; SWEETENING AGENTS; TASTE; THALAMUS;

EID: 0034628977     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-8993(00)01939-9     Document Type: Article

References (57)

1. Berger B.D. Conditioning of food aversions by injections of psychoactive drugs. J. Comp. Phys. Psychol. 81:1972;21-26.
2. Bevins R.A., Delzer T.A., Bardo M.T. Second-order conditioning detects unexpressed morphine- induced salt aversion. Anim. Learn. Behav. 24:1996;221-229.
3. Cappell H., LeBlanc A.E. Conditioned aversion to saccharin by single administrations of mescaline and d-amphetamine. Psychopharmacology. 22:1971;352-356.
4. Cappell H., LeBlanc A.E., Endrenyi L. Aversive conditioning by psychoactive drugs: effects of morphine, alcohol and chlordiazepoxide. Psychopharmacology. 29:1973;239-246.
5. Carroll M.E., Smith J.C. Time course of radiation-induced taste aversion conditioning. Physiol. Behav. 13:1974;809-812.
6. Ferrari C.M., O'Connor D.A., Riley A.L. Cocaine-induced taste aversion: effect of route of administration. Pharmacol. Biochem. Behav. 38:1991;267-271.
7. Flaherty C.F., Checke S. Anticipation of incentive gain. Anim. Learn. Behav. 10:1982;177-182.
8. Flaherty C.F., Grigson P.S. From contrast to reinforcement: role of response contingency in anticipatory contrast. J. Exp. Psychol.: Anim. Behav. Process. 14:1988;165-176.
9. Flaherty C.F., Grigson P.S., Checke S., Hnat K.C. Deprivation state and temporal horizons in anticipatory contrast. J. Exp. Psychol.: Anim. Behav. Process. 17:1991;503-518.
10. Flaherty C.F., Turovsky J., Krauss K.L. Relative hedonic value modulates anticipatory contrast. Physiol. Behav. 55:1994;1047-1054.
11. Flynn F.W., Grill H.J., Schulkin J., Norgren R. Central gustatory lesions: II. Effects on sodium appetite, taste aversion learning, and feeding behaviors. Behav. Neurosci. 105:1991;944-954.
12. Flynn F.W., Grill H.J., Schwartz G.J., Norgren R. Central gustatory lesions: I. Preferences and taste reactivity tests. Behav. Neurosci. 105:1991;933-943.
13. Garcia J., Kimeldorf D.J., Koelling R.A. Conditioned aversions to saccharin resulting from exposure to gamma radiation. Science. 122:1955;157-158.
14. Glowa J.R., Shaw A.E., Riley A.L. Cocaine-induced conditioned taste aversions: comparisons between effects in LEW/N and F344/N rat strains. Psychopharmacology. 114:1994;229-232.
15. Gomez F., Grigson P.S. The suppressive effects of LiCl, sucrose, and drugs of abuse are modulated by sucrose concentration in food deprived rats. Physiol. Behav. 67:1999;351-357.
16. Goudie A.J. Aversive stimulus properties of drugs. Neuropharmacology. 18:1979;971-979.
17. A.J. Goudie, Aversive stimulus properties of drugs: the conditioned taste aversion paradigm, in: A. Greenshaw, C.T. Dourish (Eds.), Experimental Psychopharmacology, Dourish, Humana Press, Clifton, NJ, 1987.
18. Grill H.J., Norgren R. Chronically decerebrate rats demonstrate satiation but not bait shyness. Science. 201:1978;267-269.
19. Grigson P.S. Conditioned taste aversions and drugs of abuse: a reinterpretation. Behav. Neurosci. 111:1997;129-136.
20. P.S. Grigson, C.S. Freet, The suppressive effects of sucrose and cocaine, but not LiCl, are greater in Lewis than Fischer rats: evidence for the reward comparison hypothesis, submitted.
21. Grigson P.S., Lyuboslavsky P.N., Tanase D., Wheeler R.A. Water deprivation prevents morphine-, but not LiCl-induced, suppression of sucrose intake. Physiol. Behav. 67:1999;277-286.
22. Grigson P.S., Reilly S., Shimura T., Norgren R. Ibotenic acid lesions of the parabrachial nucleus and conditioned taste aversion: further evidence for an associative deficit in rats. Behav. Neurosci. 112:1998;160-171.
23. Guitart X., Beitner-Johnson D., Marby D.W., Kosten T.A., Nestler E.J. Fischer and Lewis rat strains differ in basal levels of neurofilament proteins and their regulation by chronic morphine in the mesolimbic dopamine system. Synapse. 12:1992;242-253.
24. Hunt T., Amit Z. Conditioned taste aversion induced by self-administered drugs: paradox revisited. Neurosci. Biobehav. Rev. 11:1987;107-130.
25. Hunt T., Switzman L., Amit Z. Involvement of dopamine in the aversive stimulus properties of cocaine in rats. Pharmacol. Biochem. Behav. 22:1985;945-948.
26. Kosar E., Grill H.J., Norgren R. Gustatory cortex in the rat: II. Thalamocortical projections. Brain Res. 379:1986;342-352.
27. Kosten T.A., Miserendino M.J.D., Chi S., Nestler E.J. Fischer and Lewis rat strains show differential cocaine effects in conditioned place preference and behavioral sensitization but not in locomotor activity or conditioned taste aversion. J. Pharmacol. Exp. Ther. 269:1994;137-144.
28. Kosten T.A., Miserendino M.J.D., Haile C.N., DeCaprio J.L., Jatlow P.I., Neslter E.J. Acquisition and maintenance of intravenous cocaine self-administration in Lewis and Fischer inbred rat strains. Brain Res. 778:1997;418-429.
29. LeBlanc A.E., Cappell H. Antagonism of morphine-induced aversive conditioning by naloxone. Pharmacol. Biochem. Behav. 3:1975;185-188.
30. Mackey W.B., Keller J., van der Kooy D. Visceral cortex lesions block conditioned taste aversions induced by morphine. Pharmacol. Biochem. Behav. 24:1986;71-78.
31. Norgren R. Taste pathways to hypothalamus and amygdala. J. Comp. Neurol. 166:1976;17-30.
32. R. Norgren, Central neural mechanisms of taste, in: M. Brookhart, V.M. Mountcastle (Eds.), Handbook of Physiology: Sec. 1. The Nervous System: Vol. 3. Sensory Processes, American Physiology Society, Bethesda, MD, 1984, pp. 1087-1128.
33. R. Norgren, Gustatory system, in: G. Paxinos (Ed.), The Rat Nervous System, 2nd edn., Academic Press, San Diego, 1995, pp. 751-771.
34. Oakley B., Pfaffmann C. Electrophysiologically monitored lesions in the gustatory thalamic relay of the albino rat. J. Comp. Physiol. Psychol. 55:1962;155-160.
35. Palmerino C.C., Rusiniak K.W., Garcia J. Flavor-illness aversions: the peculiar roles of odor and tastes in memory for poison. Science. 208:1980;753-755.
36. Parker L.A. Taste reactivity responses elicited by reinforcing drugs: a dose-response analysis. Behav. Neurosci. 105:1991;955-964.
37. Parker L.A. Rewarding drugs produce taste avoidance, but not taste aversion. Neurosci. Biobehav. Rev. 19:1995;143-151.
38. Parker L.A., Carvell T. Orofacial and somatic responses elicited by lithium-, nicotine- and amphetamine-paired sucrose solution. Pharmacol. Biochem. Behav. 24:1986;883-887.
39. Pritchard T.C., Scott T.R. Amino acids as taste stimuli: T. Neural and behavioral attributes. Brain Res. 253:1982;81-92.
40. Pritchard T.C., Scott T.R. Amino acids as taste stimuli: U. Quality coding. Brain Res. 253:1982;93-104.
41. Reicher M.A., Holman E.W. Location preference and flavor aversion reinforced by amphetamine in rats. Anim. Learn. Behav. 5:1977;343-346.
42. Reilly S. The role of the gustatory thalamus in taste-guided behavior. Neurosci. Biobehav. Rev. 22:1999;883-901.
43. Reilly S., Grigson P.S., Norgren R. Parabrachial nucleus lesions and conditioned taste aversion: evidence supporting an associative deficit. Behav. Neurosci. 107:1993;1005-1017.
44. Reilly S., Pritchard T.C. Gustatory thalamus lesions in the rat: I. Innate taste preferences and aversion. Behav. Neurosci. 110:1996;737-745.
45. Reilly S., Pritchard T.C. Gustatory thalamus lesions in the rat: II. Aversive and appetitive taste conditioning. Behav. Neurosci. 110:1996;746-759.
46. Reilly S., Pritchard T.C. Gustatory thalamus lesions in the rat: III. Simultaneous contrast and autoshaping. Physiol. Behav. 62:1997;1355-1363.
47. Reilly S., Trifunovic R. Gustatory thalamus lesions eliminate successive negative contrast in rats. Behav. Neurosci. 113:1999;1242-1248.
48. Revusky S., Bedarf E.W. Association of illness with prior ingestion of novel foods. Science. 155:1967;219-220.
49. Salamone J.D. The involvement of nucleus accumbens dopamine in appetitive and aversive motivation. Behav. Brain Res. 61:1994;117-133.
50. Scalera G., Grigson P.S., Norgren R. Gustatory functions, sodium appetite, and conditioned taste aversion survive excitotoxic lesions of the thalamic taste area. Behav. Neurosci. 111:1997;633-645.
51. Spector A.C., Norgren R., Grill H.J. Parabrachial gustatory lesions impair taste aversion learning in rats. Behav. Neurosci. 106:1992;147-161.
52. Wheeler R.A., Romero-Cierpial E., Grigson P.S. Food deprivation disrupts the suppressive effects of cocaine in the CTA paradigm. Soc. Neurosci. Abstr. 24(2):1998;2174.
53. White N., Sklar L., Amit Z. The reinforcing action of morphine and its paradoxical side effect. Psychopharmacology. 52:1977;63-66.
54. Wise R.A., Yokel R.A., DeWit H. Both positive reinforcement and conditioned aversion from amphetamine and from apomorphine in rats. Science. 191:1976;1273-1275.
55. Wirsig C.R., Grill H.J. Contribution of the rat's neocortex to ingestive control: I. Latent learning for the taste of sodium chloride. J. Comp. Physiol. Psychol. 96:1982;615-627.
56. Wolf G., DiCara L.V., Braun J.J. Sodium appetite in rats after neocortical ablation. Physiol. Behav. 5:1970;1265-1269.
57. Zito K.A., Bechara A., Greenwood C., van der Kooy D. The dopamine innervation of the visceral cortex mediates the aversive effects of opiates. Pharmacol. Biochem. Behav. 30:1988;693-699.