메뉴 건너뛰기




Volumn 19, Issue 4, 2006, Pages 390-396

From individual to population: The minimum alveolar concentration curve

Author keywords

Concentration response; General anesthesia; Mechanisms of anesthesia; Minimum alveolar concentration; Steepness

Indexed keywords

HALOTHANE; INHALATION ANESTHETIC AGENT; PROPOFOL;

EID: 33745906549     PISSN: 09527907     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.aco.0000236138.31099.fc     Document Type: Review
Times cited : (11)

References (31)
  • 1
    • 0013815474 scopus 로고
    • Minimum alveolar anesthetic concentration: A standard of anesthetic potency
    • Eger EI II, Saidman LJ, Brandstater B. Minimum alveolar anesthetic concentration: a standard of anesthetic potency. Anesthesiology 1965; 26:756-763.
    • (1965) Anesthesiology , vol.26 , pp. 756-763
    • Eger II, E.I.1    Saidman, L.J.2    Brandstater, B.3
  • 2
    • 0028043659 scopus 로고
    • The interaction of fentanyl on the Cp50 of propofol for loss of consciousness and skin incision
    • Smith C, McEwan AI, Jhaveri R, et al. The interaction of fentanyl on the Cp50 of propofol for loss of consciousness and skin incision. Anesthesiology 1994; 81:820-828.
    • (1994) Anesthesiology , vol.81 , pp. 820-828
    • Smith, C.1    McEwan, A.I.2    Jhaveri, R.3
  • 3
    • 0016593310 scopus 로고
    • MAC expanded: AD50 and AD95 values of common inhalation anesthetics in man
    • De Jong RH, Eger ED. MAC expanded: AD50 and AD95 values of common inhalation anesthetics in man. Anesthesiology 1975; 42:384-389.
    • (1975) Anesthesiology , vol.42 , pp. 384-389
    • De Jong, R.H.1    Eger, E.D.2
  • 4
    • 0025843517 scopus 로고
    • Clinical characteristics of desflurane in surgical patients: Minimum alveolar concentration
    • Rampil IJ, Lockhart SH, Zwass MS, et al. Clinical characteristics of desflurane in surgical patients: minimum alveolar concentration. Anesthesiology 1991; 74:429-433.
    • (1991) Anesthesiology , vol.74 , pp. 429-433
    • Rampil, I.J.1    Lockhart, S.H.2    Zwass, M.S.3
  • 5
    • 0023221687 scopus 로고
    • The minimum alveolar concentration (MAC) of sevoflurane in humans
    • Katoh T, Ikeda K. The minimum alveolar concentration (MAC) of sevoflurane in humans. Anesthesiology 1987; 66:301-303.
    • (1987) Anesthesiology , vol.66 , pp. 301-303
    • Katoh, T.1    Ikeda, K.2
  • 6
    • 0036067233 scopus 로고    scopus 로고
    • Concepts and correlations relevant to general anaesthesia
    • Urban BW, Bleckwenn M. Concepts and correlations relevant to general anaesthesia. Br J Anaesth 2002; 89:3-16.
    • (2002) Br J Anaesth , vol.89 , pp. 3-16
    • Urban, B.W.1    Bleckwenn, M.2
  • 7
    • 0038503506 scopus 로고    scopus 로고
    • Basic pharmacology of volatile anesthetics
    • Moody E, Skolnick P, editors. Boca Raton: CRC Press
    • Dilger J. Basic pharmacology of volatile anesthetics. In: Moody E, Skolnick P, editors. Molecular bases of anesthesia. Boca Raton: CRC Press; 2001. pp. 1-35.
    • (2001) Molecular Bases of Anesthesia , pp. 1-35
    • Dilger, J.1
  • 8
    • 0021984147 scopus 로고
    • Halothane, isoflurane, and enflurane MAC in pregnant and nonpregnant female and male mice and rats
    • Mazze RI, Rice SA, Baden JM. Halothane, isoflurane, and enflurane MAC in pregnant and nonpregnant female and male mice and rats. Anesthesiology 1985; 62:339-341.
    • (1985) Anesthesiology , vol.62 , pp. 339-341
    • Mazze, R.I.1    Rice, S.A.2    Baden, J.M.3
  • 9
    • 0028073174 scopus 로고
    • Mutations conferring new patterns of sensitivity to volatile anesthetics in Caenorhabditis elegans
    • Morgan P, Sedensky M. Mutations conferring new patterns of sensitivity to volatile anesthetics in Caenorhabditis elegans. Anesthesiology 1994; 81:888-898.
    • (1994) Anesthesiology , vol.81 , pp. 888-898
    • Morgan, P.1    Sedensky, M.2
  • 10
    • 0016258476 scopus 로고
    • The effect of inhalational anaesthetics on the swimming velocity of Tetrahymena pyriformis
    • Nunn JF, Sturrock JE, Wills EJ, et al. The effect of inhalational anaesthetics on the swimming velocity of Tetrahymena pyriformis. J Cell Sci 1974; 15:537-554.
    • (1974) J Cell Sci , vol.15 , pp. 537-554
    • Nunn, J.F.1    Sturrock, J.E.2    Wills, E.J.3
  • 11
    • 0014820833 scopus 로고
    • Minimum alveolar concentrations in man on awakening from methoxyflurane, halothane, ether and fluroxene anesthesia: MAC awake
    • Stoelting RK, Longnecker DE, Eger EI II. Minimum alveolar concentrations in man on awakening from methoxyflurane, halothane, ether and fluroxene anesthesia: MAC awake. Anesthesiology 1970; 33:5-9.
    • (1970) Anesthesiology , vol.33 , pp. 5-9
    • Stoelting, R.K.1    Longnecker, D.E.2    Eger II, E.I.3
  • 12
    • 9244249221 scopus 로고    scopus 로고
    • Sevoflurane decreases bispectral index values more than does halothane at equal MAC multiples
    • Schwab HS, Seeberger MD, Eger EI II, et al. Sevoflurane decreases bispectral index values more than does halothane at equal MAC multiples. Anesth Analg 2004; 99:1723-1727.
    • (2004) Anesth Analg , vol.99 , pp. 1723-1727
    • Schwab, H.S.1    Seeberger, M.D.2    Eger II, E.I.3
  • 13
    • 23944446091 scopus 로고    scopus 로고
    • Different conditions that could result in the bispectral index indicating an incorrect hypnotic state
    • Dahaba AA. Different conditions that could result in the bispectral index indicating an incorrect hypnotic state. Anesth Analg 2005; 101:765-773.
    • (2005) Anesth Analg , vol.101 , pp. 765-773
    • Dahaba, A.A.1
  • 14
    • 23044492151 scopus 로고    scopus 로고
    • Molecular and systemic mechanisms of general anaesthesia: The 'multisite and multiple mechanisms' concept
    • Grasshoff C, Rudolph U, Antkowiak B. Molecular and systemic mechanisms of general anaesthesia: the 'multisite and multiple mechanisms' concept. Curr Opin Anaesthesiol 2005; 18:386-391. An excellent review of anesthetic mechanisms, emphasizing the importance of neuronal circuits.
    • (2005) Curr Opin Anaesthesiol , vol.18 , pp. 386-391
    • Grasshoff, C.1    Rudolph, U.2    Antkowiak, B.3
  • 15
    • 25144459104 scopus 로고    scopus 로고
    • Emerging molecular mechanisms of general anesthetic action
    • Hemmings HC Jr, Akabas MH, Goldstein PA, et al. Emerging molecular mechanisms of general anesthetic action. Trends Pharmacol Sci 2005; 26:503-510. An excellent review of anesthetic mechanisms, emphasizing the importance of individual ion channel targets.
    • (2005) Trends Pharmacol Sci , vol.26 , pp. 503-510
    • Hemmings Jr., H.C.1    Akabas, M.H.2    Goldstein, P.A.3
  • 16
    • 0027467413 scopus 로고
    • Anesthetic potency (MAC) is independent of forebrain structures in the rat
    • Rampil I, Mason P, Singh H. Anesthetic potency (MAC) is independent of forebrain structures in the rat. Anesthesiology 1993; 78:707-712.
    • (1993) Anesthesiology , vol.78 , pp. 707-712
    • Rampil, I.1    Mason, P.2    Singh, H.3
  • 17
    • 0027136076 scopus 로고
    • Exaggerated anesthetic requirements in the preferentially anesthetized brain
    • Antognini JF, Schwartz K. Exaggerated anesthetic requirements in the preferentially anesthetized brain. Anesthesiology 1993; 79:1244-1249.
    • (1993) Anesthesiology , vol.79 , pp. 1244-1249
    • Antognini, J.F.1    Schwartz, K.2
  • 18
    • 0344994597 scopus 로고    scopus 로고
    • Quantitative and qualitative effects of isoflurane on movement occurring after noxious stimulation
    • Antognini JF, Wang XW, Carstens E. Quantitative and qualitative effects of isoflurane on movement occurring after noxious stimulation. Anesthesiology 1999; 91:1064-1071.
    • (1999) Anesthesiology , vol.91 , pp. 1064-1071
    • Antognini, J.F.1    Wang, X.W.2    Carstens, E.3
  • 19
    • 0036785886 scopus 로고    scopus 로고
    • The sedative component of anesthesia is mediated by GABA(A) receptors in an endogenous sleep pathway
    • Nelson LE, Guo TZ, Lu J, et al. The sedative component of anesthesia is mediated by GABA(A) receptors in an endogenous sleep pathway. Nat Neurosci 2002; 5:979-984.
    • (2002) Nat Neurosci , vol.5 , pp. 979-984
    • Nelson, L.E.1    Guo, T.Z.2    Lu, J.3
  • 20
    • 13244254005 scopus 로고    scopus 로고
    • Neocortex is the major target of sedative concentrations of volatile anaesthetics: Strong depression of firing rates and increase of GABA-A receptor-mediated inhibition
    • Hentschke H, Schwarz C, Antkowiak B. Neocortex is the major target of sedative concentrations of volatile anaesthetics: strong depression of firing rates and increase of GABA-A receptor-mediated inhibition. Eur J Neurosci 2005; 21:93-102. The authors used a combination of in-vivo and in-vitro techniques to ascribe a role for the neocortex in sedation by volatile anesthetics.
    • (2005) Eur J Neurosci , vol.21 , pp. 93-102
    • Hentschke, H.1    Schwarz, C.2    Antkowiak, B.3
  • 21
    • 0041375505 scopus 로고    scopus 로고
    • Inhaled anesthetics and immobility: Mechanisms, mysteries, and minimum alveolar anesthetic concentration
    • Sonner JM, Antognini JF, Dutton RC, et al. Inhaled anesthetics and immobility: mechanisms, mysteries, and minimum alveolar anesthetic concentration. Anesth Analg 2003; 97:718-740.
    • (2003) Anesth Analg , vol.97 , pp. 718-740
    • Sonner, J.M.1    Antognini, J.F.2    Dutton, R.C.3
  • 22
    • 0037315741 scopus 로고    scopus 로고
    • General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA(A) receptor beta3 subunit
    • Jurd R, Arras M, Lambert S, et al. General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA(A) receptor beta3 subunit. FASEB J 2003; 17:250-252.
    • (2003) FASEB J , vol.17 , pp. 250-252
    • Jurd, R.1    Arras, M.2    Lambert, S.3
  • 23
    • 24144442832 scopus 로고    scopus 로고
    • Isoflurane disrupts central pattern generator activity and coordination in the lamprey isolated spinal cord
    • Jinks SL, Atherley RJ, Dominguez CL, et al. Isoflurane disrupts central pattern generator activity and coordination in the lamprey isolated spinal cord. Anesthesiology 2005; 103:567-575. This paper uses a new approach to search for the anatomical site of MAC.
    • (2005) Anesthesiology , vol.103 , pp. 567-575
    • Jinks, S.L.1    Atherley, R.J.2    Dominguez, C.L.3
  • 24
    • 3342886087 scopus 로고    scopus 로고
    • Mitochondrial complex I function affects halothane sensitivity in Caenorhabditis elegans
    • Kayser EB, Morgan PG, Sedensky MM. Mitochondrial complex I function affects halothane sensitivity in Caenorhabditis elegans. Anesthesiology 2004; 101:365-372.
    • (2004) Anesthesiology , vol.101 , pp. 365-372
    • Kayser, E.B.1    Morgan, P.G.2    Sedensky, M.M.3
  • 25
    • 0035020938 scopus 로고    scopus 로고
    • Relevant concentrations of inhaled anesthetics for in vitro studies of anesthetic mechanisms
    • Eger E II, Fisher D, Dilger J, et al. Relevant concentrations of inhaled anesthetics for in vitro studies of anesthetic mechanisms. Anesthesiology 2001; 94:915-921.
    • (2001) Anesthesiology , vol.94 , pp. 915-921
    • Eger II, E.1    Fisher, D.2    Dilger, J.3
  • 26
    • 0036712854 scopus 로고    scopus 로고
    • Issues in the design and interpretation of minimum alveolar anesthetic concentration (MAC) studies
    • Sonner JM. Issues in the design and interpretation of minimum alveolar anesthetic concentration (MAC) studies. Anesth Analg 2002; 95:609-614.
    • (2002) Anesth Analg , vol.95 , pp. 609-614
    • Sonner, J.M.1
  • 27
    • 0028140369 scopus 로고
    • Molecular and cellular mechanisms of general anaesthesia
    • Franks N, Lieb W. Molecular and cellular mechanisms of general anaesthesia. Nature 1994; 367:607-614.
    • (1994) Nature , vol.367 , pp. 607-614
    • Franks, N.1    Lieb, W.2
  • 28
    • 0032841430 scopus 로고    scopus 로고
    • On the relevance of clinically relevant concentrations of inhaled anesthetics in in vitro experiments
    • Eckenhoff R, Johansson J. On the relevance of clinically relevant concentrations of inhaled anesthetics in in vitro experiments. Anesthesiology 1999; 91:856-860.
    • (1999) Anesthesiology , vol.91 , pp. 856-860
    • Eckenhoff, R.1    Johansson, J.2
  • 29
    • 0037315656 scopus 로고    scopus 로고
    • Computational aspects of anesthetic action in simple neural models
    • Gottschalk A, Haney P. Computational aspects of anesthetic action in simple neural models. Anesthesiology 2003; 98:548-564.
    • (2003) Anesthesiology , vol.98 , pp. 548-564
    • Gottschalk, A.1    Haney, P.2
  • 30
    • 33745878171 scopus 로고    scopus 로고
    • Interactions of anesthetics with their targets: Nonspecific, specific or both?
    • Epub ahead of print
    • Urban BW, Bleckwenn M, Barann M. Interactions of anesthetics with their targets: Nonspecific, specific or both? Pharmacol Ther 2006; [Epub ahead of print]. If you want to know how the sensitivity of your favorite anesthetic target compares with others, check out the figures, especially Figure 24!
    • (2006) Pharmacol Ther
    • Urban, B.W.1    Bleckwenn, M.2    Barann, M.3
  • 31
    • 3142751597 scopus 로고    scopus 로고
    • Multi-path system of the neural network can explain the steep dose-response of MAC
    • Kaminoh Y, Kamaya H, Tashiro C, et al. Multi-path system of the neural network can explain the steep dose-response of MAC. J Anesth 2004; 18:94-99.
    • (2004) J Anesth , vol.18 , pp. 94-99
    • Kaminoh, Y.1    Kamaya, H.2    Tashiro, C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.