-
1
-
-
0013815474
-
Minimum alveolar anesthetic concentration: A standard of anesthetic potency
-
Eger EI II, Saidman LJ, Brandstater B. Minimum alveolar anesthetic concentration: a standard of anesthetic potency. Anesthesiology 1965; 26:756-763.
-
(1965)
Anesthesiology
, vol.26
, pp. 756-763
-
-
Eger II, E.I.1
Saidman, L.J.2
Brandstater, B.3
-
2
-
-
0028043659
-
The interaction of fentanyl on the Cp50 of propofol for loss of consciousness and skin incision
-
Smith C, McEwan AI, Jhaveri R, et al. The interaction of fentanyl on the Cp50 of propofol for loss of consciousness and skin incision. Anesthesiology 1994; 81:820-828.
-
(1994)
Anesthesiology
, vol.81
, pp. 820-828
-
-
Smith, C.1
McEwan, A.I.2
Jhaveri, R.3
-
3
-
-
0016593310
-
MAC expanded: AD50 and AD95 values of common inhalation anesthetics in man
-
De Jong RH, Eger ED. MAC expanded: AD50 and AD95 values of common inhalation anesthetics in man. Anesthesiology 1975; 42:384-389.
-
(1975)
Anesthesiology
, vol.42
, pp. 384-389
-
-
De Jong, R.H.1
Eger, E.D.2
-
4
-
-
0025843517
-
Clinical characteristics of desflurane in surgical patients: Minimum alveolar concentration
-
Rampil IJ, Lockhart SH, Zwass MS, et al. Clinical characteristics of desflurane in surgical patients: minimum alveolar concentration. Anesthesiology 1991; 74:429-433.
-
(1991)
Anesthesiology
, vol.74
, pp. 429-433
-
-
Rampil, I.J.1
Lockhart, S.H.2
Zwass, M.S.3
-
5
-
-
0023221687
-
The minimum alveolar concentration (MAC) of sevoflurane in humans
-
Katoh T, Ikeda K. The minimum alveolar concentration (MAC) of sevoflurane in humans. Anesthesiology 1987; 66:301-303.
-
(1987)
Anesthesiology
, vol.66
, pp. 301-303
-
-
Katoh, T.1
Ikeda, K.2
-
6
-
-
0036067233
-
Concepts and correlations relevant to general anaesthesia
-
Urban BW, Bleckwenn M. Concepts and correlations relevant to general anaesthesia. Br J Anaesth 2002; 89:3-16.
-
(2002)
Br J Anaesth
, vol.89
, pp. 3-16
-
-
Urban, B.W.1
Bleckwenn, M.2
-
7
-
-
0038503506
-
Basic pharmacology of volatile anesthetics
-
Moody E, Skolnick P, editors. Boca Raton: CRC Press
-
Dilger J. Basic pharmacology of volatile anesthetics. In: Moody E, Skolnick P, editors. Molecular bases of anesthesia. Boca Raton: CRC Press; 2001. pp. 1-35.
-
(2001)
Molecular Bases of Anesthesia
, pp. 1-35
-
-
Dilger, J.1
-
8
-
-
0021984147
-
Halothane, isoflurane, and enflurane MAC in pregnant and nonpregnant female and male mice and rats
-
Mazze RI, Rice SA, Baden JM. Halothane, isoflurane, and enflurane MAC in pregnant and nonpregnant female and male mice and rats. Anesthesiology 1985; 62:339-341.
-
(1985)
Anesthesiology
, vol.62
, pp. 339-341
-
-
Mazze, R.I.1
Rice, S.A.2
Baden, J.M.3
-
9
-
-
0028073174
-
Mutations conferring new patterns of sensitivity to volatile anesthetics in Caenorhabditis elegans
-
Morgan P, Sedensky M. Mutations conferring new patterns of sensitivity to volatile anesthetics in Caenorhabditis elegans. Anesthesiology 1994; 81:888-898.
-
(1994)
Anesthesiology
, vol.81
, pp. 888-898
-
-
Morgan, P.1
Sedensky, M.2
-
10
-
-
0016258476
-
The effect of inhalational anaesthetics on the swimming velocity of Tetrahymena pyriformis
-
Nunn JF, Sturrock JE, Wills EJ, et al. The effect of inhalational anaesthetics on the swimming velocity of Tetrahymena pyriformis. J Cell Sci 1974; 15:537-554.
-
(1974)
J Cell Sci
, vol.15
, pp. 537-554
-
-
Nunn, J.F.1
Sturrock, J.E.2
Wills, E.J.3
-
11
-
-
0014820833
-
Minimum alveolar concentrations in man on awakening from methoxyflurane, halothane, ether and fluroxene anesthesia: MAC awake
-
Stoelting RK, Longnecker DE, Eger EI II. Minimum alveolar concentrations in man on awakening from methoxyflurane, halothane, ether and fluroxene anesthesia: MAC awake. Anesthesiology 1970; 33:5-9.
-
(1970)
Anesthesiology
, vol.33
, pp. 5-9
-
-
Stoelting, R.K.1
Longnecker, D.E.2
Eger II, E.I.3
-
12
-
-
9244249221
-
Sevoflurane decreases bispectral index values more than does halothane at equal MAC multiples
-
Schwab HS, Seeberger MD, Eger EI II, et al. Sevoflurane decreases bispectral index values more than does halothane at equal MAC multiples. Anesth Analg 2004; 99:1723-1727.
-
(2004)
Anesth Analg
, vol.99
, pp. 1723-1727
-
-
Schwab, H.S.1
Seeberger, M.D.2
Eger II, E.I.3
-
13
-
-
23944446091
-
Different conditions that could result in the bispectral index indicating an incorrect hypnotic state
-
Dahaba AA. Different conditions that could result in the bispectral index indicating an incorrect hypnotic state. Anesth Analg 2005; 101:765-773.
-
(2005)
Anesth Analg
, vol.101
, pp. 765-773
-
-
Dahaba, A.A.1
-
14
-
-
23044492151
-
Molecular and systemic mechanisms of general anaesthesia: The 'multisite and multiple mechanisms' concept
-
Grasshoff C, Rudolph U, Antkowiak B. Molecular and systemic mechanisms of general anaesthesia: the 'multisite and multiple mechanisms' concept. Curr Opin Anaesthesiol 2005; 18:386-391. An excellent review of anesthetic mechanisms, emphasizing the importance of neuronal circuits.
-
(2005)
Curr Opin Anaesthesiol
, vol.18
, pp. 386-391
-
-
Grasshoff, C.1
Rudolph, U.2
Antkowiak, B.3
-
15
-
-
25144459104
-
Emerging molecular mechanisms of general anesthetic action
-
Hemmings HC Jr, Akabas MH, Goldstein PA, et al. Emerging molecular mechanisms of general anesthetic action. Trends Pharmacol Sci 2005; 26:503-510. An excellent review of anesthetic mechanisms, emphasizing the importance of individual ion channel targets.
-
(2005)
Trends Pharmacol Sci
, vol.26
, pp. 503-510
-
-
Hemmings Jr., H.C.1
Akabas, M.H.2
Goldstein, P.A.3
-
16
-
-
0027467413
-
Anesthetic potency (MAC) is independent of forebrain structures in the rat
-
Rampil I, Mason P, Singh H. Anesthetic potency (MAC) is independent of forebrain structures in the rat. Anesthesiology 1993; 78:707-712.
-
(1993)
Anesthesiology
, vol.78
, pp. 707-712
-
-
Rampil, I.1
Mason, P.2
Singh, H.3
-
17
-
-
0027136076
-
Exaggerated anesthetic requirements in the preferentially anesthetized brain
-
Antognini JF, Schwartz K. Exaggerated anesthetic requirements in the preferentially anesthetized brain. Anesthesiology 1993; 79:1244-1249.
-
(1993)
Anesthesiology
, vol.79
, pp. 1244-1249
-
-
Antognini, J.F.1
Schwartz, K.2
-
18
-
-
0344994597
-
Quantitative and qualitative effects of isoflurane on movement occurring after noxious stimulation
-
Antognini JF, Wang XW, Carstens E. Quantitative and qualitative effects of isoflurane on movement occurring after noxious stimulation. Anesthesiology 1999; 91:1064-1071.
-
(1999)
Anesthesiology
, vol.91
, pp. 1064-1071
-
-
Antognini, J.F.1
Wang, X.W.2
Carstens, E.3
-
19
-
-
0036785886
-
The sedative component of anesthesia is mediated by GABA(A) receptors in an endogenous sleep pathway
-
Nelson LE, Guo TZ, Lu J, et al. The sedative component of anesthesia is mediated by GABA(A) receptors in an endogenous sleep pathway. Nat Neurosci 2002; 5:979-984.
-
(2002)
Nat Neurosci
, vol.5
, pp. 979-984
-
-
Nelson, L.E.1
Guo, T.Z.2
Lu, J.3
-
20
-
-
13244254005
-
Neocortex is the major target of sedative concentrations of volatile anaesthetics: Strong depression of firing rates and increase of GABA-A receptor-mediated inhibition
-
Hentschke H, Schwarz C, Antkowiak B. Neocortex is the major target of sedative concentrations of volatile anaesthetics: strong depression of firing rates and increase of GABA-A receptor-mediated inhibition. Eur J Neurosci 2005; 21:93-102. The authors used a combination of in-vivo and in-vitro techniques to ascribe a role for the neocortex in sedation by volatile anesthetics.
-
(2005)
Eur J Neurosci
, vol.21
, pp. 93-102
-
-
Hentschke, H.1
Schwarz, C.2
Antkowiak, B.3
-
21
-
-
0041375505
-
Inhaled anesthetics and immobility: Mechanisms, mysteries, and minimum alveolar anesthetic concentration
-
Sonner JM, Antognini JF, Dutton RC, et al. Inhaled anesthetics and immobility: mechanisms, mysteries, and minimum alveolar anesthetic concentration. Anesth Analg 2003; 97:718-740.
-
(2003)
Anesth Analg
, vol.97
, pp. 718-740
-
-
Sonner, J.M.1
Antognini, J.F.2
Dutton, R.C.3
-
22
-
-
0037315741
-
General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA(A) receptor beta3 subunit
-
Jurd R, Arras M, Lambert S, et al. General anesthetic actions in vivo strongly attenuated by a point mutation in the GABA(A) receptor beta3 subunit. FASEB J 2003; 17:250-252.
-
(2003)
FASEB J
, vol.17
, pp. 250-252
-
-
Jurd, R.1
Arras, M.2
Lambert, S.3
-
23
-
-
24144442832
-
Isoflurane disrupts central pattern generator activity and coordination in the lamprey isolated spinal cord
-
Jinks SL, Atherley RJ, Dominguez CL, et al. Isoflurane disrupts central pattern generator activity and coordination in the lamprey isolated spinal cord. Anesthesiology 2005; 103:567-575. This paper uses a new approach to search for the anatomical site of MAC.
-
(2005)
Anesthesiology
, vol.103
, pp. 567-575
-
-
Jinks, S.L.1
Atherley, R.J.2
Dominguez, C.L.3
-
24
-
-
3342886087
-
Mitochondrial complex I function affects halothane sensitivity in Caenorhabditis elegans
-
Kayser EB, Morgan PG, Sedensky MM. Mitochondrial complex I function affects halothane sensitivity in Caenorhabditis elegans. Anesthesiology 2004; 101:365-372.
-
(2004)
Anesthesiology
, vol.101
, pp. 365-372
-
-
Kayser, E.B.1
Morgan, P.G.2
Sedensky, M.M.3
-
25
-
-
0035020938
-
Relevant concentrations of inhaled anesthetics for in vitro studies of anesthetic mechanisms
-
Eger E II, Fisher D, Dilger J, et al. Relevant concentrations of inhaled anesthetics for in vitro studies of anesthetic mechanisms. Anesthesiology 2001; 94:915-921.
-
(2001)
Anesthesiology
, vol.94
, pp. 915-921
-
-
Eger II, E.1
Fisher, D.2
Dilger, J.3
-
26
-
-
0036712854
-
Issues in the design and interpretation of minimum alveolar anesthetic concentration (MAC) studies
-
Sonner JM. Issues in the design and interpretation of minimum alveolar anesthetic concentration (MAC) studies. Anesth Analg 2002; 95:609-614.
-
(2002)
Anesth Analg
, vol.95
, pp. 609-614
-
-
Sonner, J.M.1
-
27
-
-
0028140369
-
Molecular and cellular mechanisms of general anaesthesia
-
Franks N, Lieb W. Molecular and cellular mechanisms of general anaesthesia. Nature 1994; 367:607-614.
-
(1994)
Nature
, vol.367
, pp. 607-614
-
-
Franks, N.1
Lieb, W.2
-
28
-
-
0032841430
-
On the relevance of clinically relevant concentrations of inhaled anesthetics in in vitro experiments
-
Eckenhoff R, Johansson J. On the relevance of clinically relevant concentrations of inhaled anesthetics in in vitro experiments. Anesthesiology 1999; 91:856-860.
-
(1999)
Anesthesiology
, vol.91
, pp. 856-860
-
-
Eckenhoff, R.1
Johansson, J.2
-
29
-
-
0037315656
-
Computational aspects of anesthetic action in simple neural models
-
Gottschalk A, Haney P. Computational aspects of anesthetic action in simple neural models. Anesthesiology 2003; 98:548-564.
-
(2003)
Anesthesiology
, vol.98
, pp. 548-564
-
-
Gottschalk, A.1
Haney, P.2
-
30
-
-
33745878171
-
Interactions of anesthetics with their targets: Nonspecific, specific or both?
-
Epub ahead of print
-
Urban BW, Bleckwenn M, Barann M. Interactions of anesthetics with their targets: Nonspecific, specific or both? Pharmacol Ther 2006; [Epub ahead of print]. If you want to know how the sensitivity of your favorite anesthetic target compares with others, check out the figures, especially Figure 24!
-
(2006)
Pharmacol Ther
-
-
Urban, B.W.1
Bleckwenn, M.2
Barann, M.3
-
31
-
-
3142751597
-
Multi-path system of the neural network can explain the steep dose-response of MAC
-
Kaminoh Y, Kamaya H, Tashiro C, et al. Multi-path system of the neural network can explain the steep dose-response of MAC. J Anesth 2004; 18:94-99.
-
(2004)
J Anesth
, vol.18
, pp. 94-99
-
-
Kaminoh, Y.1
Kamaya, H.2
Tashiro, C.3
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