Quantitative and qualitative effects of isoflurane on movement occurring after noxious stimulation

Anesthesiology

Volumn 91, Issue 4, 1999, Pages 1064-1071

  Antognini, Joseph F ^a   Wang, Xiao Wei ^b   Carstens, E ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NONE

Author keywords

Brain; Pain; Spinal cord

Indexed keywords

ISOFLURANE;

ANIMAL EXPERIMENT; ARTICLE; DRUG EFFECT; DRUG POTENCY; HEAD MOVEMENT; LIMB MOVEMENT; MALE; MINIMUM LUNG ALVEOLUS CONCENTRATION; NOCICEPTIVE STIMULATION; NONHUMAN; PAIN; PRIORITY JOURNAL; RAT;

ANESTHETICS, INHALATION; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; EXTREMITIES; HALOTHANE; ISOFLURANE; MALE; MOVEMENT; PAIN MEASUREMENT; PULMONARY ALVEOLI; RATS;

EID: 0344994597     PISSN: 00033022     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000542-199910000-00027     Document Type: Article

References (26)

1. Eger EI II, Saidman LJ, Brandstater B: Minimum alveolar anesthetic concentration: A standard of anesthetic potency. ANESTHESIOLOGY 1965; 26:756-63
2. Antognini JF, Carstens E: A simple, quantifiable, and accurate method for applying a noxious mechanical stimulus. Anesth Analg 1998; 87:1446-9
3. Zar JH: Biostatistical Analysis, 4th Edition. Upper Saddle River, NJ, Prentice Hall, 1999, pp 273-81
4. de Jong RH, Wagman IH: Block of afferent impulses in the dorsal horn of monkey: A possible mechanism of anesthesia. Exp Neurol 1968; 20:352-58
5. Antognini JF, Carstens E: Increasing isoflurane from 0.9 to 1.1 minimum alveolar concentration minimally affects dorsal horn cell responses to noxious stimulation. ANESTHESIOLOGY 1999; 90:208-14
6. Gordon J: Spinal mechanisms of motor coordination, Principles of Neural Science, 3rd Edition. Edited by Kandel ER, Schwartz JH, Jessell TM. Norwalk, CT, Appleton and Lange, 1991, pp 581-95
7. Cazalets JR, Borde M, Clarac F: Localization and organization of the central pattern generator for hindlimb locomotion in newborn rat. J Neurosci 1995; 15:4943-51
8. Yamamura T, Harada K, Okamura A, Kemmotsu O: Is the site of action of ketamine anesthesia the N-methyl-D-aspartate receptor? ANESTHESIOLOGY 1990; 72:704-10
9. King BS, Rampil IJ: Anesthetic depression of spinal motor neurons may contribute to lack of movement in response to noxious stimuli. ANESTHESIOLOGY 1994; 81:1484-92
10. Zhou HH, Jin TT, Qin B, Turndorf H: Suppression of spinal cord motoneuron excitability correlates with surgical immobility during isoflurane anesthesia. ANESTHESIOLOGY 1998; 88:955-61
11. Nicoll RA, Madison DV: General anesthetics hyperpolarize neurons in the vertebrate central nervous system. Science 1982; 217: 1055-57
12. Sirois JE, Pancrazio JJ, Lynch C III, Bayliss DA: Multiple ionic mechanisms mediate inhibition of rat motoneurons by inhalation anaesthetics. J Physiol 1998; 512:851-62
13. Schouenborg J, Kalliomäki J: Functional organization of the nociceptive withdrawal reflexes. I. Activation of hindlimb muscles in the rat. Exp Brain Res 1990; 83:67-78
14. Schouenborg J, Weng H-R, Holmberg H: Modular organization of spinal nociceptive reflexes: A new hypothesis. News Physiol Sci 1994; 9:261-65
15. Schouenborg J, Weng H-R, Kalliomäki J, Holmberg H: A survery of spinal dorsal horn neurones encoding the spatial organization of withdrawal reflexes in the rat. Exp Brain Res 1995; 106:19-27
16. Jasmin L, Carstens E, Basbaum AI: Interneurons presynaptic to rat tail flick motoneurons as mapped by transneuronal transport of pseudorabies virus: Few have long ascending collaterals. Neuroscience 1997; 76:859-76
17. Davis M: The mammalian startle response, Neural Mechanisms of Startle Behavior. Edited by Eaton RC. New York, Plenum Press, 1984, pp 287-351
18. Chiasson RB: Laboratory Anatomy of the White Rat. Dubuque, IA Brown Publishers, 1988, pp 96
19. Christie JM, O'Lenic TD, Cane RD: Head turning in brain death. J Clin Anesth 1996; 8:141-3
20. Rampil IJ, Mason P, Singh H: Anesthetic potency (MAC) is independent of forebrain structures in the rat. ANESTHESIOLOGY 1993; 78:707-12
21. Antognini JF, Schwartz K: Exaggerated anesthetic requirements in the preferentially anesthetized brain. ANESTHESIOLOGY 1993; 79:1244-49
22. Rampil IJ: Anesthetic potency is not altered after hypothermie spinal cord transection in rats. ANESTHESIOLOGY 1994; 80:606-10
23. Carstens E, Wilson CG: Rat tail flick reflex: Magnitude measurement of stimulus-response function, suppression by morphine, and habituation. J Neurophysiol 1993; 70:630-39
24. Carstens E, Ansley D: Hindlimb flexion withdrawal evoked by noxious heat in conscious rats: magnitude measurement of stimulus-response function, suppression by morphine, and habituation. J Neurophysiol 1993; 70:621-29
25. Quasha AL, Eger EI, Tinker JH: Determination and applications of MAC. ANESTHESIOLOGY 1980; 53:315-34
26. Todd MM, Weeks JB, Warner DS: A focal cryogenic brain lesion does not reduce the minimum alveolar concentration for halothane in rats. ANESTHESIOLOGY 1993; 79:139-43