Labeling of antibiotics for infection diagnosis

Quarterly Journal of Nuclear Medicine and Molecular Imaging

Volumn 50, Issue 2, 2006, Pages 147-152

  Benitez, A ^a   Roca, M ^a   Martin Comin, J ^a  

^a BELLVITGE BIOMEDICAL RESEARCH INSTITUTE IDIBELL   (Spain)

Author keywords

Ceftizoxime; Cephalosporins; Ciprofloxacin; Enrofloxacin; Fluoroquinolones; Infection; Radionuclide imaging; Sparfloxacin; Technetium Tc99m Sesramibi

Indexed keywords

ANTIBIOTIC AGENT; CEFTIZOXIME TC 99M; CIPROFLOXACIN TC 99M; COLLOID TC 99M; ENROFLOXACIN TC 99M; GALLIUM 67; INDIUM 111; LEVOFLOXACIN TC 99M; MEDRONATE TECHNETIUM TC 99M; NORFLOXACIN TC 99M; OFLOXACIN; PERTECHNETIC ACID TC 99M; RADIOPHARMACEUTICAL AGENT; SPARFLOXACIN TC 99M; UNCLASSIFIED DRUG;

BONE INFECTION; BONE SCINTISCANNING; CELL LABELING; CLINICAL TRIAL; DIAGNOSTIC ACCURACY; DIAGNOSTIC VALUE; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG METABOLISM; DRUG TISSUE LEVEL; DRUG UPTAKE; EARLY DIAGNOSIS; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; GASTROINTESTINAL INFECTION; HUMAN; INFECTION; LEUKOCYTE; NONHUMAN; PREDICTION; PROSTHESIS INFECTION; REVIEW; SCINTIGRAPHY; SENSITIVITY AND SPECIFICITY;

ANIMALS; ANTI-BACTERIAL AGENTS; HUMANS; IMAGE ENHANCEMENT; INFECTION; ISOTOPE LABELING; POSITRON-EMISSION TOMOGRAPHY; RADIOISOTOPES; RADIOPHARMACEUTICALS;

EID: 33745880660     PISSN: 18244785     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (32)

1. Becker W. The contribution of nuclear medicine to the patient with infection. Eur J Nucl Med 1995;22:1195-211.
2. Becker W, Meller J. The role of nuclear medicine in infection and inflammation. Lancet Infect Dis 2001;1:326-33.
3. 99mTc-infecton. A new class of radiopharmaceutical for imaging infection. J Nucl Med 1993;34 Suppl:119P.
4. DeNardo GL. When is too much too much and yet not enough? Alas, a plethora of opportunities but where's the beef? J Nucl Med 2000;41:470-3.
5. 99m infecton for the localisation of bacterial infection. Eur J Nucl Med 1997;24:553-6.
6. 99mTc-HMPAO leukocyte scintigraphy. J Nucl Med 2001;42:567-74.
7. 99mTc-ciprofloxacin scintigraphy in a rabbit model of Staphilococcus aureux prosthetic joint infection. J Nucl Med 2002;43:239-45.
8. Kashyap R, Vinjamuri S, Hall AV, Das SS, Solanki KK, Britton KE. Imaging bacterial infection with a radiolabelled antibiotic. In: Cox PH, Buscombe JR, editors. The imaging of infection and inflammation. Amsterdam: Kluwer Academic Publishers; 1998.p.219-27.
9. 99mTc-Levofloxacin: An agent for infection imaging. Indian J Nucl Med 2003;18:16.
10. 99m labeled sparfloxacin: a specific infection imaging agent. World J Nucl Med 2003;: 103-9.
11. 99mTc-Ciprofloxacin. J Nucl Med 2004;45:2088-95.
12. 99mTc]. Rev Esp Med Nucl 2000;19:479-83.
13. 99mTc infecton imaging with radiolabelled white-cell imaging in the evaluation of bacterial infection. Lancet 1996;347:233-5.
14. Hooper DC, Wolfson JS, Ng EY, Swartz MN. Mechanisms of action of and resistance to ciprofloxacin. Am J Med 1987;82:12-20.
15. O'Donnell JA, Gelone SP. Fluoroquinolones. Infect Dis Clin North Am 2000;14:489-513, xi.
16. King DE, Malone R, Lilley SH. New classification and update on the quinolone antibiotics. Am Fam Physician 2000;61:2741-8.
17. 99mTc-Infecton, a novel agent for detecting sites of infection. J Clin Path 1998;51:215-9.
18. 99mTc-ciprofloxacin, a promising agent for the diagnosis of bacterial infection. Eur J Nucl Med 2001;28:570-4.
19. Easmon CSF, Crane JP, Blowers A. Effect of ciprofloxacin on intracellular organisms: in-vitro and in-vivo studies. J Antimicrob Chemother 1986;18 Suppl D:43-8.
20. 99mTc-"infecton", preliminaiy evaluation in over 500 patients through an IAEA co-ordinated research programme. Eur J Nucl Med 1998;25:OS 152.
21. 99mTc-white-blood cell and three-phase bone imaging in the diagnosis of hip prosthesis infections: improved diagnostic accuracy with extended imaging time. Nucl Med Commun 2002;23:655-61.
22. Dumarey N, Blocklet D, Appelboom T, Tant L, Schoutens A. Infecton is not specific for bacterial osteo-articular infective pathology. Eur J Nucl Med Mol Imaging 2002;29:530-5.
23. 99mTc-Ciprofloxacin scintigraphy to discriminate between septic and sterile osteoarticular diseases. J Nucl Med 2003;44:920-6.
24. 99m)Tc-ciprofloxacin (Infecton). J Clin Pathol 2002;55:817-23.
25. 99mTc-Ciprofloxacin in pyrexia of unknown origin. Fur J Nucl Med, 2005;32 Suppl 1:S226:P538.
26. 99mTc-ciprofloxacin. Hepatogastroenterology 2005;52:491-5.
27. Hooper DC, Wolfson JS, Ng EY, Swartz MN. Mechanisms of action of and resistance to ciprofloxacin. Am J Med 1987;82:12-20.
28. 99mTechnetium-labelled peptide-HYNIC conjugales: effects of lipophilicity and stability on biodistribution. Nucl Med Biol 1999;26:389-96.
29. 99mTc-ciprofloxacin. Eur J Nucl Med 2000;27;PS-224.
30. Pu KP, Neu HC. Antibacterial activity of ceftizoxime, a beta-lactamase-stable cephalosporin. Antimicrob Agents Chemother 1980;17:583-90.
31. 99m-ceftizoxime in animal model infection and inflammation. Eur J Nucl Med 2000;27:970.
32. 99mTc radiollabeled antibiotic. Eur J Nucl Med 2005;32 Suppl 1:S226-P539.