FXYD proteins: Novel regulators of Na,K-ATPase;Les protéines FXYD: Nouveaux régulateurs de la Na,K-ATPase

Medecine/Sciences

Volumn 22, Issue 6-7, 2006, Pages 633-638

  Delprat, Benjamin ^a   Bibert, Stéphanie ^a   Geering, Käthi ^a  

^a UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ARGININE; DYSADHERIN; GLYCINE; MEMBRANE PROTEIN; PROTEIN FXYD; PROTEIN FXYD 1; PROTEIN FXYD 2; PROTEIN FXYD 4; PROTEIN FXYD 7; SERINE; UNCLASSIFIED DRUG;

GENE MUTATION; HYPOMAGNESEMIA; KIDNEY TUBULE ABSORPTION; MUSCLE CONTRACTION; NERVE EXCITABILITY; POTASSIUM TRANSPORT; REVIEW; SODIUM TRANSPORT;

EID: 33745876562     PISSN: 07670974     EISSN: None     Source Type: Journal    
DOI: 10.1051/medsci/20062267633     Document Type: Review

References (39)

1. Horisberger JD. Recent insights into the structure and mechanism of the sodium pump. Physiology (Bethesda) 2004; 19: 377-87.
2. Geering K. The functional role of β subunits in oligomeric P-type ATPases. J Bioenerg Biomembr 2001; 33: 425-38.
3. Crambert G, Hasler U, Beggah AT, et al. Transport and pharmacological properties of nine different human Na,K-ATPase isozymes. J Biol Chem 2000; 275: 1976-86.
4. Feraille E, Doucet A. Sodium-potassium-adenosinetriphosphatase-dependent sodium transport in the kidney: hormonal control. Physiol Rev 2001; 81: 345-418.
5. Sweadner KJ, Rael E. The FXYD gene family of small ion transport regulators or channels: cCNA sequence, protein signature sequence, and expression. Genomics 2000; 68: 41-56.
6. Pdlmer CJ, Scott BT, Jones LR. Purification and complete sequence determination of the major plasma membrane substrate for cAMP-dependent protein kinase and protein kinase C in myocardium. J Biol Chem 1991; 266: 11126-30.
7. Mercer RW, Biemesderfer D, Bliss DP, et al. Molecular cloning and immunological characterization of the γ-polypeptide, a small protein associated with the Na,K-ATPase. J Cell Biol 1993; 121: 579-86.
8. Morrison BW, Moorman JR, Kowdley GC, et al. Mat-8, a novel phospholemman-like protein expressed in human breast tumors, induces a chloride conductance in Xenopus oocytes. J Biol Chem 1995; 270: 2176-82.
9. + channel activity in Xenopus oocytes. Proc Natl Acad Sci USA 1995; 92: 6092-6.
10. Fu X, Kamps M. E2a-Pbx1 induces aberrant expression of tissue-specific and developmentally regulated genes when expressed in NIH 3T3 fibroblasts. Mol Cell Biol 1997; 17: 1503-12.
11. Yamaguchi F, Yamaguchi K, Tai V, et al. Molecular cloning and characterization of a novel phospholemman-like protein from rat hippocampus. Brain Res Mol Brain Res 2001; 86: 189-92.
12. Béguin P, Crambert G, Monnet-Tschudi F, et al. FXYD7 is a brain-specific regulator of Na,K-ATPase α1-β isozymes. EMBO J 2002; 21: 3264-73.
13. Béguin P, Wang XY, Firsov D, et al. The γ subunit is a specific component of the Na,K-ATPase and modulates its transport properties. EMBO J 1997; 16: 4250-60.
14. Béguin P, Crambert G, Guennoun S, et al. CHIF, a member of the FXYD protein family, is a regulator of Na,K-ATPase distinct from the γ-subunit. EMBO J 2001; 20: 3993-4002.
15. Moorman JR, Palmer CJ, John III JE, et al. Phospholemman expression induces a hyperpolarization-activated chloride current in Xenopus oocytes. J Biol Chem 1992; 267: 14551-4.
16. Crambert G, Geering K. FXYD proteins: New tissue-specific regulators of the ubiquitous Na,K- ATPase. Sci STKE 2003; 166: RE1.
17. Cornelius F, Mahmmoud YA. Functional modulation of the sodium pump: The regulatory proteins "Fixit". News Physiol Sci 2003; 18: 119-24.
18. Garty H, Karlish SJ. Role of FXYD proteins in ion transport. Annu Rev Physiol 2005; 25: 25.
19. Therien AG, Pu HX, Karlish SJ, Blostein R. Molecular and functional studies of the gamma subunit of the sodium pump. J Bioenerg Biomembr 2001; 33: 407-14.
20. Moorman JR, Ackerman SJ, Kowdley GC, et al. Unitary onion currents trough phospholemman channel molecules. Nature 1995; 377: 737-40.
21. Crambert G, Fuzesi M, Garty H, et al. Phospholemman (FXYD1) associates with Na,K-ATPase and regulates its transport properties. Proc Natl Acad Sci USA 2002; 99: 11476-81.
22. Jia LG, Donnet C, Bogaev RC, et al. Hypertrophy, increased ejection fraction, and reduced Na-K-ATPase activity in phospholemman-deficient mice. Am J Physiol Heart Circ Physiol 2005; 288: H1982-8.
23. +], transients in adult rat cardiac myocytes. Am J Physiol Heart Circ Physiol 2004; 286: H1322-30.
24. Kuster B, Shainskaya A, Pu HX, et al. A new variant of the γ subunit of renal. Na,K-ATPase. Identification by mass spectrometry, antibody binding, and expression in cultured cells. J Biol Chem 2000; 275: 18441-6.
25. Pu HX, Cluzeaud F, Goldshlegger R et, al. Functional role and immunocytochemical localization of the γa and γb forms of the Na,K-ATPase γ sufaunit. J Biol Chem 2001; 276: 20370-8.
26. Therien AG, Goldshleger R, Karlish SJ, Blostein R. Tissue-specific distribution and modulatory role of the γ subunit of the Na,K-ATPase. J Biol Chem 1997; 272: 32628-34.
27. + affinity of the renal Na,K-ATPase. J Biol Chem 1999; 274: 33183-5.
28. + affinity and decreased thermal stability. J Biol Chem 2005; 280: 19003-11.
29. +-ATPase γ-subunit. Nat Genet 2000; 26: 265-6.
30. Crambert G, Li C, Swee LK, Geering K. FXYD7: Mapping of functional sites involved in endoplasmic reticulum export, association with and regulation of Na,K-ATPase. J Biol Chem 2004; 279: 30888-95.
31. Pu HX, Scanzano R, Blostein R. Distinct regulatory effects of the Na,K-ATPase γ subunit. J Biol Chem 2002; 277: 20270-6.
32. Crambert G, Li C, Claeys D, Geering K. FXYD3 (Mat-8), a new regulator of Na,K-ATPase. Mol Biol Cell 2005; 16: 2363-71.
33. Grzmil M, Voigt S, Thelen P, et al. Up-regulated expression of the MAT-8 gene in prostate cancer and its siRNA-mediated inhibition of expression induces a decrease in proliferation of human prostate carcinoma cells. Int J Oncol 2004; 24: 97-105.
34. Shi H, Levy-Holzman R, Cluzeaud F, et al. Membrane topology and immunolocalization of CHIF in kidney and intestine. Am J Physiol 2001; 280: F505-12.
35. Garty H, Lindzen M, Scanzano R, et al. A functional interaction between CHIF and Na-K-ATPase: implication for regulation by FXYD proteins. Am J Physiol 2002; 283: F607-15.
36. Goldschimdt I, Grahammer F, Warth R, et al. Kidney and colon electrolyte transport in CHIF knockout mice. Cell Physiol Biochem 2004; 14: 113-20.
37. Lubarski I, Pihakaski-Maunsbach K, Karlish SJ, et al. Interaction with the Na, K ATPase and tissue distribution of FXYD5 (RIC). J Biol Chem 2005; 7:7.
38. Ino Y, Gotoh M, Sakamoto M, et al. Dysadherin, a cancer-associated cell membrane glycoprotein, down-regulates E-cadherin and promotes metastasis. PNAS 2002; 99: 365-70.
39. Saito S, Matoba R, Kato K, Matsubara K. Expression of a novel member of the ATP1G1/PLM/MAT8 family, phospholemman-like protein (PLP) gene, in the developmental process of mouse cerebellum. Gene 2001; 279: 149-55.