Defensive nature of Sargassum polycystum (Brown alga) against acetaminophen-induced toxic hepatitis in rats: Role of drug metabolizing microsomal enzyme system, tumor necrosis factor-α and fate of liver cell structural integrity

World Journal of Gastroenterology

Volumn 12, Issue 24, 2006, Pages 3829-3834

  Balaji Raghavendran, H ^a   Sathivel, A ^a   Devaki, T ^a  

^a UNIVERSITY OF MADRAS   (India)

Author keywords

Acetaminophen; Free radical; NAPQI; Sargassum polycystum; Toxic hepatitis

Indexed keywords

CYTOCHROME B5; CYTOCHROME P450; DRUG METABOLIZING ENZYME; FLAVONOID; N ACETYL 1,4 BENZOQUINONE IMINE; PARACETAMOL; PLANT EXTRACT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE FERRIHEMOPROTEIN REDUCTASE; SARGASSUM EXTRACT; TERPENOID DERIVATIVE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL ASSAY; CELL FATE; CELL ISOLATION; CELL PROTECTION; CELL STRUCTURE; CONTROLLED STUDY; DRUG DOSE REGIMEN; DRUG MECHANISM; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOPATHOLOGY; LIVER CELL; LIVER MICROSOME; LIVER PROTECTION; MALE; MITOCHONDRIAL TOXICITY; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN DETERMINATION; PROTEIN FUNCTION; RAT; RAT STRAIN; SARGASSUM; SEROLOGY; STRUCTURE ANALYSIS; TOXIC HEPATITIS; TRANSMISSION ELECTRON MICROSCOPY;

EID: 33745862022     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v12.i24.3829     Document Type: Article

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