Differential changes in respiratory capacity and ischemia tolerance of isolated mitochondria from atrophied and hypertrophied hearts

Metabolism: Clinical and Experimental

Volumn 55, Issue 8, 2006, Pages 1097-1106

  Bugger, Heiko ^a   Chemnitius, Jörg Michael ^a   Doenst, Torsten ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE DIPHOSPHATE; CITRATE SYNTHASE; CYTOCHROME C OXIDASE; OXYGEN; PROSTAGLANDIN SYNTHASE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; AORTA; ARTICLE; ATROPHY; CONTROLLED STUDY; ELECTRODE; GENE EXPRESSION; HEART HYPERTROPHY; HEART MUSCLE ATROPHY; HEART MUSCLE FIBER MEMBRANE; HEART MUSCLE ISCHEMIA; HETEROTOPIC TRANSPLANTATION; MALE; MITOCHONDRION; NONHUMAN; OXYGEN CONSUMPTION; PRIORITY JOURNAL; RAT; RAT STRAIN; RESPIRATORY CHAIN; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STATISTICAL SIGNIFICANCE;

ADENOSINE DIPHOSPHATE; ANIMALS; ATROPHY; BODY WEIGHT; CARDIOMEGALY; CITRATE (SI)-SYNTHASE; CYTOCHROMES C; ELECTRON TRANSPORT; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HEART DISEASES; MALE; MITOCHONDRIA, HEART; MUSCLE PROTEINS; MYOCARDIAL ISCHEMIA; MYOCARDIAL REPERFUSION INJURY; NADH DEHYDROGENASE; ORGAN SIZE; OXYGEN CONSUMPTION; RATS; RATS, WISTAR; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 33745854284     PISSN: 00260495     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.metabol.2006.04.005     Document Type: Article

References (38)

1. Depre C., Shipley G.L., Chen W., et al. Unloaded heart in vivo replicates fetal gene expression of cardiac hypertrophy. Nat Med 4 (1998) 1269-1275
2. Taber R.E., Morales A.R., and Fine G. Myocardial necrosis and the postoperative low-cardiac-output syndrome. Ann Thorac Surg 4 (1967) 12-27
3. Cooley D.A., Reul G.J., and Wukasch D.C. Ischemic contracture of the heart: "stone heart". Am J Cardiol 29 (1972) 575-577
4. Weber J.R. Left ventricular hypertrophy. Its prime importance as a controllable risk factor. Am Heart J 116 (1988) 272-279
5. Anderson P.G., Allard M.F., Thomas G.D., et al. Increased ischemic injury but decreased hypoxic injury in hypertrophied rat hearts. Circ Res 67 (1990) 948-959
6. Anderson P.G., Bishop S.P., and Digerness S.B. Transmural progression of morphologic changes during ischemia and reperfusion in the normal and hypertrophied rat heart. Am J Pathol 129 (1987) 142-167
7. Sullivan J.M., Vander Zwaag R., El-Zeky F., et al. Left ventricular hypertrophy: effect on survival. J Am Coll Cardiol 22 (1993) 508-513
8. Sink J.D., Pellom G.L., Currie W.D., et al. Response of hypertrophied myocardium to ischemia: correlation with biochemical and physiological parameters. J Thorac Cardiovasc Surg 81 (1981) 865-872
9. Peyton R.B., Van Trigt P., Pellom G.L., et al. Improved tolerance to ischemia in hypertrophied myocardium by preischemic enhancement of adenosine triphosphate. J Thorac Cardiovasc Surg 84 (1982) 11-15
10. Suzuki K., Murtuza B., Smolenski R.T., et al. Development of an in-vivo ischemia-reperfusion model in heterotopically transplanted rat hearts. Transplantation 73 (2002) 1398-1402
11. Bove E.L., and Stammers A.H. Recovery of left ventricular function after hypothermic global ischemia. Age-related differences in the isolated working rabbit heart. J Thorac Cardiovasc Surg 91 (1986) 115-122
12. Yano Y., Braimbridge M.V., and Hearse D.J. Protection of the pediatric myocardium. Differential susceptibility to ischemic injury of the neonatal rat heart. J Thorac Cardiovasc Surg. 94 (1987) 887-896
13. Nishioka K., and Jarmakani J.M. Effects of ischemia on mechanical function and high-energy phosphates in rabbit myocardium. Am J Physiol 242 (1982) H1077-H1083
14. Julia P., Kofsky E.R., Buckberg G.D., et al. Studies of myocardial protection in the immature heart. III. Models of ischemic and hypoxic/ischemic injury in the immature puppy heart. J Thorac Cardiovasc Surg 101 (1991) 14-22
15. Murashita T., Borgers M., and Hearse D.J. Developmental changes in tolerance to ischemia in the rabbit heart: disparity between interpretations of structural, enzymatic and functional indices of injury. J Mol Cell Cardiol 24 (1992) 1143-1154
16. Page E., and McCallister L.P. Quantitative electron microscopic description of heart muscle cells. Am J Cardiol 31 (1973) 172-181
17. Weinstein E.S., Benson D.W., and Ratcliffe D.J. Experimental myocardial ischemia. Differential injury of mitochondrial subpopulations. Arch Surg 120 (1985) 332-338
18. Matlib M.A., Rebman D., Ashraf M., et al. Differential activities of putative subsarcolemmal and interfibrillar mitochondria from cardiac muscle. J Mol Cell Cardiol 13 (1981) 163-170
19. Palmer J.W., Tandler B., and Hoppel C.L. Biochemical differences between subsarcolemmal and interfibrillar mitochondria from rat cardiac muscle: effects of procedural manipulations. Arch Biochem Biophys 236 (1985) 691-702
20. Chemnitius J.M., Haselmeyer K.H., Manglitz T., et al. Differential injury of mitochondrial subpopulations during myocardial ischemia. J Appl Cardiol 4 (1989) 441-453
21. Pinsky W.W., Lewis R.M., and McMillin-Wood J.B. Myocardial protection from ischemic arrest: potassium and verapamil cardioplegia. Am J Physiol 240 (1981) H326-H335
22. Ono K., and Lindsey E.S. Improved technique of heart transplantation in rats. J Thorac Cardiovasc Surg. 57 (1969) 225-229
23. Doenst T., Schlensak C., Kobba J.L., et al. A technique of heterotopic, infrarenal heart transplantation with double anastomosis in mice. J Heart Lung Transplant 20 (2001) 762-765
24. Doenst T., Goodwin G.W., Cedars A.M., et al. Load-induced changes in vivo alter substrate fluxes and insulin responsiveness of rat heart in vitro. Metabolism 50 (2001) 1083-1090
25. Jennings R.B., Reimer K.A., Hill M.L., et al. Total ischemia in dog hearts, in vitro. I. Comparison of high energy phosphate production, utilization, and depletion, and of adenine nucleotide catabolism in total ischemia in vitro vs. severe ischemia in vivo. Circ Res 49 (1981) 892-900
26. Rouslin W. Persistence of mitochondrial competence during myocardial autolysis. Am J Physiol 252 (1987) H985-H989
27. Palmer J.W., Tandler B., and Hoppel C.L. Biochemical properties of subsarcolemmal and interfibrillar mitochondria isolated from rat cardiac muscle. J Biol Chem 252 (1977) 8731-8739
28. Srere P.A. Citrate synthase. Methods Enzymol 13 (1969) 3-11
29. Chemnitius J.M., Häfner P., Kreuzer H., et al. Latent and free citrate synthase activity as enzymatic indicators for respiratory potential of isolated porcine heart mitochondria. J Appl Cardiol 3 (1988) 301-310
30. Chemnitius J.M., Manglitz T., Kloeppel M., et al. Rapid preparation of subsarcolemmal and interfibrillar mitochondrial subpopulations from cardiac muscle. Int J Biochem 25 (1993) 589-596
31. Taegtmeyer H., King L.M., and Jones B.E. Energy substrate metabolism, myocardial ischemia, and targets for pharmacotherapy. Am J Cardiol 82 (1998) 54K-60K
32. Jennings R.B., Herdson P.B., and Sommers H.M. Structural and functional abnormalities in mitochondria isolated from ischemic dog myocardium. Lab Invest 20 (1969) 548-557
33. Taegtmeyer H. Switching metabolic genes to build a better heart. Circulation 106 (2002) 2043-2045
34. Whitehouse S., Cooper R.H., and Randle P.J. Mechanism of activation of pyruvate dehydrogenase by dichloroacetate and other halogenated carboxylic acids. J Biochem 141 (1974) 761-774
35. McVeigh J.J., and Lopaschuk G.D. Dichloroacetate stimulation of glucose oxidation improves recovery of ischemia rat hearts. Am J Physiol 259 (1990) H1079-H1085
36. Broderick T.L., Quinney H.A., and Lopaschuk G.D. Carnitine stimulation of glucose oxidation in the fatty acid perfused isolated working rat heart. J Biol Chem 267 (1992) 3758-3763
37. Broderick T.L., Quinney H.A., Barker C.C., et al. Beneficial effect of carnitine on mechanical recovery of rat hearts reperfused after a transient period of global ischemia is accompanied by a stimulation of glucose oxidation. Circulation 87 (1993) 972-981
38. Lopaschuk G.D., Wambolt R.B., and Barr R.L. An imbalance between glycolysis and glucose oxidation is a possible explanation for the detrimental effects of high levels of fatty acids during aerobic reperfusion of ischemia hearts. J Pharmacol Exp Ther 264 (1993) 135-144