The effect of the β-emitting yttrium-90 citrate on the dose-response of dicentric chromosomes in human lymphocytes: A basis for biological dosimetry after radiosynoviorthesis

Radiation and Environmental Biophysics

Volumn 45, Issue 2, 2006, Pages 93-98

  Schmid, E ^a   Selbach, H J ^b   Voth, M ^c   Pinkert, J ^c   Gildehaus, F J ^a   Klett, R ^d   Haney, M ^e  

^a UNIVERSITY OF MUNICH   (Germany)

^b Physikalisch Technische Bundesanstalt ^*  (Germany)

^c BAYER PHARMA AG   (Germany)

^d UNIVERSITY HOSPITAL GIESSEN   (Germany)

^e INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL DAMAGE; CHROMOSOMES; LYMPHATIC DRAINAGE; RADIOSYNOVIORTHESIS;

BLOOD; CELLS; COLLOIDS; DOSIMETRY; RADIATION HAZARDS; YTTRIUM;

RADIOACTIVE WASTES;

CITRIC ACID; YTTRIUM 90;

ARTICLE; BLOOD SAMPLING; CALCULATION; DICENTRIC CHROMOSOME; DOSE RESPONSE; DOSIMETRY; ELECTRON; HUMAN; HUMAN CELL; LYMPHOCYTE; MONTE CARLO METHOD; RADIATION; RADIATION EXPOSURE; RADIOSYNOVIORTHESIS; RELATIVE BIOLOGIC EFFECTIVENESS; SYNOVIORTHESIS; X RAY;

BETA PARTICLES; BETA RAYS; CHROMOSOME ABERRATIONS; CITRATES; DOSE-RESPONSE RELATIONSHIP, RADIATION; HUMANS; INJECTIONS, INTRA-ARTICULAR; LYMPHOCYTES; MALE; MONTE CARLO METHOD; ORGANOMETALLIC COMPOUNDS; RADIOPHARMACEUTICALS; RELATIVE BIOLOGICAL EFFECTIVENESS; SYNOVITIS; X-RAYS;

EID: 33745833043     PISSN: 0301634X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00411-006-0045-4     Document Type: Article

References (28)

1. IAEA (1986) Biological dosimetry: chromosomal aberration analysis for dose assessment. IAEA Technical Reports (Vienna), Series 260, pp 1-68
2. Stevenson AC, Bedford J, Dolphin GW, Purrott RJ, Lloyd DC, Hill AGS, Hill HFH, Gumpel JM, Williams D, Scott JT, Ramsey HW, Bruckner FE, Fearn BDA (1973) Cytogenetic and scoring study of patients receiving intra-articular injections of gold-198 and yttrium-90. Ann Rheum Dis 32:112-123
3. Jalava S, Salonius AC (1974) Chromosomes of patients treated with yttrium-90. Lancet 1:807
4. Gumpel JM, Stevenson AC (1974) Chromosomal damage after intra-articular injection of different colloids of yttrium 90. Rheumatol Rehabil 14:7-12
5. Doyle DV, Glass JS, Gow PJ, Daker M, Grahame R (1977) A clinical and prospective chromosomal study of yttrium-90 synovectomy. Rheumatol Rehabil 16:217-222
6. Lloyd DC, Reeder EJ (1978) Chromosome aberrations and intra-articular yttrium-90. Lancet 1:617
7. Williams PL, Crawley JCW, Freeman AM, Lloyd DC, Gumpel JM (1981) Feasibility of out-patient management after intra-articular yttrium-90: comparison of two regimens. Br Med J 282:13-14
8. ICRP (2003) Relative biological effectiveness (RBE), quality factor (Q), and radiation weighting factor (wR). Annals of the ICRP, Publication 92. Pergamon Press, Oxford
9. Hori TA, Nakai S (1978) Unusual dose-response of chromosome aberrations induced in human lymphocytes by very low dose exposures to tritium. Mutat Res 50:101-110
10. Prosser JS, Lloyd DC, Edwards AA, Stather JW (1983) The induction of chromosome aberrations in human lymphocytes by exposure to tritiated water in vitro. Radiat Prot Dosimetry 4:21-26
11. Vulpis N (1984) The induction of chromosome aberrations in human lymphocytes by in vitro irradiation with (-particles from tritiated water. Radiat Res 97:511-518
12. Lloyd DC, Moquet JE, Oram S, Edwards AA, Lucas JN (1998) Accidental intake of tritiated water: a cytogenetic follow-up case on translocation stability and dose reconstruction. Int J Radiat Biol 73:543-547
13. Deng W, Morrison DP, Gale KI, Lucas JN (1998) Biological dosimetry of beta-ray exposure from tritium using chromosome translocations in human lymphocytes analysed by fluorescence in situ hybridisation. Radiat Res 150:400-405
14. 90Sr (-particles in cultured human lymphocytes. Mutat Res 163:277-283
15. Watt DE (1996) Quantities for dosimetry of ionizing radiations in liquid water. Taylor & Francis, London
16. Schmid E, Bauchinger M, Streng S, Nahrstedt U (1984) The effect of 220 kVp x-rays with different spectra on the dose response of chromosome aberrations in human lymphocytes. Radiat Environ Biophys 23:305-309
17. Wagner R, Schmid E, Bauchinger M (1983) Application of conventional and FPG staining for the analysis of chromosome aberrations induced by low levels of dose in human lymphocytes. Mutat Res 109:65-71
18. Krumrey M, Ulm G, Schmid E (2004) Dicentric chromosomes in monolayers of human lymphocytes produced by monochromatized synchrotron radiation with photon energies from 1.83 to 17.4 keV. Radiat Environ Biophys 43:1-6
19. Bauchinger M, Schmid E (1998) LET dependence of yield ratios of radiation-induced intra- and interchromosomal aberrations in human lymphocytes. Int J Radiat Biol 74:17-25
20. Briesmeister JF (2000) MCNP™ - a general Monte Carlo N-particle transport code, version 4C. Los Alamos National Laboratory, Report LA-13709-M
21. ICRU (1997) Dosimetry of external beta rays for radiation protection. ICRU Report 56:108, Bethesda
22. Tabata T, Andreo P (1998) Semiempirical formulas for the detour factor of 1- to 50-Mev electrons in condensed materials. Radiat Phys Chem 53:353-360
23. Lloyd DC, Edwards AA (1983) Chromosome aberrations in human lymphocytes: Effect of radiation quality, dose, and dose rate. In: Ishihara T, Sasaki MS (eds) Radiation-induced chromosome damage in man. Alan R. Liss, New York
24. Prosser JS, Izard BE, Brown JK, Hetherington ELR, Lambrecht RM, Cato L, Wallace M, Whithell J, Wiseman J, Hoschl R, George S, Laurent R, Butler P, Smart R, Edmonts J, Lovegrove F, Warwick A (1993) Induction of micronuclei in peripheral blood lymphocytes of patients treated for rheumatoid or osteo-arthritis of the knee with dysprosium-165 hydroxide macroaggregates or yttrium-90 silicate. Cytobios 73:7-15
25. Prosser JS, Moquet JE, Lloyd DC, Edwards AA (1988) Radiation induction of micronuclei in human lymphocytes. Mutat Res 199:37-45
26. ICRP (1991) 1990 recommendation of the international commission on radiological protection. Annals of the ICRP, vol 21, Publication 60. Pergamon Press, Oxford
27. R. Health Phys 69:954-956
28. Schmid E, Bauchinger M (1998) LET dependence of dicentric yields in human lymphocytes induced by low doses of sparsely ionizing radiations and its implication for risk assessments. Health Phys 74:719-721