The L4 22-kilodalton protein plays a role in packaging of the adenovirus genome

Journal of Virology

Volumn 80, Issue 14, 2006, Pages 6973-6981

  Ostapchuk, Philomena ^a   Anderson, Mary E ^a   Chandrasekhar, Sharanya ^a   Hearing, Patrick ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CIS ACTING ELEMENT; PROTEIN L4 22KDA; UNCLASSIFIED DRUG; VIRUS DNA; VIRUS PROTEIN;

ADENOVIRUS; ARTICLE; CONSENSUS SEQUENCE; CORRELATION ANALYSIS; DNA PACKAGING; DNA PROTEIN COMPLEX; DNA REPLICATION; GENE EXPRESSION; GENE SEQUENCE; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN MOTIF; SEQUENCE ANALYSIS; VIRUS CAPSID; VIRUS GENE; VIRUS GENOME;

ADENOVIRIDAE; BASE SEQUENCE; CAPSID; GENOME, VIRAL; HELA CELLS; HUMANS; OPEN READING FRAMES; PROMOTER REGIONS (GENETICS); PROTEIN BINDING; REPETITIVE SEQUENCES, NUCLEIC ACID; SEQUENCE DELETION; VIRAL PROTEINS; VIRUS ASSEMBLY;

ADENOVIRIDAE; MIRIDAE;

EID: 33745780727     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00123-06     Document Type: Article

References (36)

1. Bolwig, G. M., J. T. Bruder, and P. Hearing. 1992. Different binding site requirements for binding and activation for the bipartite enhancer factor EF-1A. Nucleic Acids Res. 20:6555-6564.
2. Bruder, J. T., and P. Hearing. 1991. Cooperative binding of EF-1A to the E1A enhancer region mediates synergistic effects on E1A transcription during adenovirus infection. J. Virol. 65:5084-5087.
3. Bruder, J. T., and P. Hearing. 1989. Nuclear factor EF-1A binds to the adenovirus E1A core enhancer element and to other transcriptional control regions. Mol. Cell. Biol. 9:5143-5153.
4. Chartier, C., E. Degryse, M. Gantzer, A. Dieterle, A. Pavirani, and M. Mehtali. 1996. Efficient generation of recombinant adenovirus vectors by homologous recombination in Escherichia coli. J. Virol. 70:4805-4810.
5. Erturk, E., P. Ostapchuk, S. I. Wells, J. Yang, K. Gregg, A. Nepveu, J. P. Dudley, and P. Hearing. 2003. Binding of CCAAT displacement protein CDP to adenovirus packaging sequences. J. Virol. 77:6255-6264.
6. Evans, J. D., and P. Hearing. 2003. Distinct roles of the adenovirus E4 ORF3 protein in viral DNA replication and inhibition of genome concatenation. J. Virol. 77:5295-5304.
7. Fessler, S. P., and C. S. Young. 1999. The role of the L4 33K gene in adenovirus infection. Virology 263:507-516.
8. Finnen, R. L., J. F. Biddle, and J. Flint. 2001. Truncation of the human adenovirus type 5 L4 33-kDa protein: evidence for an essential role of the carboxy-terminus in the viral infectious cycle. Virology 289:388-399.
9. Gambke, C., and W. Deppert. 1981. Late nonstructural 100,000- and 33,000-dalton proteins of adenovirus type 2. I. Subcellular localization during the course of infection. J. Virol. 40:585-593.
10. Gambke, C., and W. Deppert. 1981. Late nonstructural 100,000- and 33,000-dalton proteins of adenovirus type 2. II. Immunological and protein chemical analysis. J. Virol. 40:594-598.
11. Goncalves, M. A., I. van der Velde, J. M. Janssen, B. T. Maassen, E. H. Heemskerk, D. J. Opstelten, S. Knaan-Shanzer, D. Valerio, and A. A. de Vries. 2002. Efficient generation and amplification of high-capacity adenoassociated virus/adenovirus hybrid vectors. J. Virol. 76:10734-10744.
12. Grable, M., and P. Hearing. 1990. Adenovirus type 5 packaging domain is composed of a repeated element that is functionally redundant. J. Virol. 64:2047-2056.
13. Gustin, K. E., and M. J. Imperiale. 1998. Encapsidation of viral DNA requires the adenovirus L1 52/55-kilodalton protein. J. Virol. 72:7860-7870.
14. Gustin, K. E., P. Lutz, and M. J. Imperiale. 1996. Interaction of the adenovirus L1 52/55-kilodalton protein with the IVa2 gene product during infection. J. Virol. 70:6463-6467.
15. Hasson, T. B., P. D. Soloway, D. A. Ornelles, W. Doerfler, and T. Shenk. 1989. Adenovirus L1 52- and 55-kilodalton proteins are required for assembly of virions. J. Virol. 63:3612-3621.
16. Hearing, P., R. J. Samulski, W. L. Wishart, and T. Shenk. 1987. Identification of a repeated sequence element required for efficient encapsidation of the adenovirus type 5 chromosome. J. Virol. 61:2555-2558.
17. Hirt, B. 1967. Selective extraction of polyomavirus DNA from infected mouse cell cultures. J. Mol. Biol. 26:365-369.
18. Jansen-Durr, P., G. Mondesert, and C. Kedinger. 1989. Replication-dependent activation of the adenovirus major late promoter is mediated by the increased binding of a transcription factor to sequences in the first exon. J. Virol. 63:5124-5132.
19. Kulshreshtha, V., L. A. Babiuk, and S. K. Tikoo. 2004. Role of bovine adenovirus-3 33K protein in viral replication. Virology 323:59-69.
20. Lutz, P., and C. Kedinger. 1996. Properties of the adenovirus IVa2 gene product, an effector of late-phase-dependent activation of the major late promoter. J. Virol. 70:1396-1405.
21. Mondesert, G., C. Tribouley, and C. Kedinger. 1992. Identification of a novel downstream binding protein implicated in late-phase-specific activation of the adenovirus major late promoter. Nucleic Acids Res. 20:3881-3889.
22. Oosterom-Dragon, E. A., and C. W. Anderson. 1983. Polypeptide structure and encoding location of the adenovirus serotype 2 late, nonstructural 33K protein. J. Virol. 45:251-263.
23. Ostapchuk, P., and P. Hearing. 2005. Control of adenovirus packaging. J. Cell. Biochem. 96:25-35.
24. Ostapchuk, P., and P. Hearing. 2003. Minimal cis-acting elements required for adenovirus genome packaging. J. Virol. 77:5127-5135.
25. Ostapchuk, P., and P. Hearing. 2003. Regulation of adenovirus packaging. Curr. Top. Microbiol. Immunol. 272:165-185.
26. Ostapchuk, P., J. Yang, E. Auffarth, and P. Hearing. 2005. Functional interaction of the adenovirus IVa2 protein with adenovirus type 5 packaging sequences. J. Virol. 79:2831-2838.
27. Pardo-Mateos, A., and C. S. Y. Young. 2004. Adenovirus IVa2 protein plays an important role in transcription from the major late promoter in vivo. Virology 327:50-59.
28. Perez-Romero, P., R. E. Tyler, J. R. Abend, M. Dus, and M. J. Imperiale. 2005. Analysis of the interaction of the adenovirus L1 52/55-kilodalton and IVa2 proteins with the packaging sequence in vivo and in vitro. J. Virol. 79:2366-2374.
29. Schiedner, G., S. Hertel, and S. Kochanek. 2000. Efficient transformation of primary human amniocytes by E1 functions of Ad5: generation of new cell lines for adenoviral vector production. Hum. Gene Ther. 11:2105-2116.
30. Schmid, S. I., and P. Hearing. 1997. Bipartite structure and functional independence of adenovirus type 5 packaging elements. J. Virol. 71:3375-3384.
31. Schmid, S. I., and P. Hearing. 1998. Cellular components interact with adenovirus type 5 minimal DNA packaging domains. J. Virol. 72:6339-6347.
32. Tribouley, C., P. Lutz, A. Staub, and C. Kedinger. 1994. The product of the adenovirus intermediate gene IVa2 is a transcriptional activator of the major late promoter. J. Virol. 68:4450-4457.
33. Young, C. S. Y. 2003. The structure and function of the adenovirus major late promoter. Curr. Top. Microbiol. Immunol. 272:213-250.
34. Zhang, W., and M. J. Imperiale. 2000. Interaction of the adenovirus IVa2 protein with viral packaging sequences. J. Virol. 74:2687-2693.
35. Zhang, W., and M. J. Imperiale. 2003. Requirement of the adenovirus IVa2 protein for virus assembly. J. Virol. 77:3586-3594.
36. Zhang, W., J. A. Low, J. B. Christensen, and M. J. Imperiale. 2001. Role for the adenovirus IVa2 protein in packaging of viral DNA. J. Virol. 75:10446-10454.