Gene therapy in the neuroendocrine system

Frontiers of Hormone Research

Volumn 35, Issue , 2006, Pages 135-142

  Herenu C B ^a   Morel, G R ^a   Bellini, M J ^a   Reggiani, P C ^a   Sosa, Y E ^a   Brown, O A ^a   Goya, R G ^a,b  

^a UNIVERSIDAD NACIONAL DE LA PLATA   (Argentina)

^b INSTITUTO DE INVESTIGACIONES BIOQUÍMICAS DE LA PLATA INIBIOLP   (Argentina)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 33745774422     PISSN: 03013073     EISSN: None     Source Type: Book Series    
DOI: 10.1159/000094316     Document Type: Conference Paper

References (27)

1. Lowenstein PR, Castro MG: Recent advances in the pharmacology of neurological gene therapy. Curr Opin Pharmacol 2004;4:91-97.
2. Valtin H: Genetic models of diabetes insipidus; in Windhager EE (ed): Handbook of Physiology. New York, Oxford University Press, 1992, pp 1281-1316.
3. Geddes BJ, Harding TC, Lightman SL, Uney JB: Long-term gene therapy in the CNS: reversal of hypothalamic diabetes insipidus in the Brattleboro rat by using an adenovirus expressing arginine vasopressin. Nat Med 1997;3:1402-1404.
4. Bienemann AS, Martin-Rendon E, Cosgrave AS, Glover CP, Wong LF, Kingsman SM, Mitrophanous KA, Mazarakis ND, Uney JB: Long-term replacement of a mutated nonfunctional CNS gene: reversal of hypothalamic diabetes insipidus using an EIAV-based lentiviral vector expressing arginine vasopressin. Mol Ther 2003;7:588-596.
5. k) rats. Endocrinology 2003;144:2016-2024.
6. Li G, Mobbs CV, Scarpace PJ: Central pro-opiomelanocortin gene delivery results in hypophagia, reduced visceral adiposity, and improved insulin sensitivity in genetically obese Zucker rats. Diabetes 2003;52:1951-1957.
7. Dahlström A, Fuxe K: Evidence for the existence of monoamine containing neurons in the central nervous system. I. Demonstration of monoamines in the cell bodies of brain stem neurons. Acta Physiol Scand 1964;62:1-55.
8. Tillet Y, Kitahama K: Distribution of central catecholaminergic neurons: a comparison between ungulates, humans and other species. Histol Histopathol 1998;13:1163-1177.
9. Kawano H, Daikoku S: Functional topography of the rat hypothalamic dopamine neuron systems: retrograde tracing and immunohistochemical study. J Comp Neurol 1997;265:242-253.
10. Goudreau JL, Lindley SE, Lookingland KJ, Moore KE: Evidence that hypothalamic periventricular dopamine neurons innervate the intermediate lobe of the rat pituitary. Neuroendocrinology 1992;56:100-105.
11. Ben-Jonathan N, Arbogast LA, Hyde JF: Neuroendocrine regulation of prolactin release. Prog Neurobiol 1989;33:399-477.
12. Porter JC, Nansel DD, Gudelsky GA, Reymond MJ, Pilotte NS, Foreman MM, Tilders FJH: Some aspects of hypothalamic and hypophysial secretion in aging rats. Peptides 1980;1:135-139.
13. Reymond MJ, Porter JC: Secretion of hypothalamic dopamine into pituitary stalk blood of aged female rats. Brain Res Bull 1981;7:69-73.
14. Gudelsky GA, Nansel DD, Porter JC: Dopaminergic control of prolactin secretion in the aging male rat. Brain Res 1981;204:446-450.
15. Sánchez HL, Silva LB, Portiansky EL, Goya RG, Zuccolilli GO: Impact of very old age on hypothalamic dopaminergic neurons in the female rat: a morphometric study. J Comp Neurol 2003;458:319-325.
16. Goya RG, Lu JKH, Meites J: Gonadal function in aging rats and its relation to pituitary and mammary pathology. Mech Age Dev 1990;56:77-88.
17. Cónsole G, Gómez-Dumm CL, Brown OA, Goya RG: Sexual dimorphism in the age-changes of the pituitary lactotrophs in rats. Mech Age Dev 1997;95:157-166.
18. Franceschi M, Camerlingo M, Perego L, Bottacchi E, Mamoli A: Tubero-infundibular dopaminergic function in Parkinson's disease. Eur Neurol 1988;28:117-119.
19. Shimohama S, Sawada H, Kitamura Y, Taniguchi T: Disease model: Parkinson's disease. Trends Mol Med 2003;9:360-365.
20. de Rijk MC, Breteler MM, Graveland GA, Ott A, Grobbee DE, van der Meche FG, Hofman A: Prevalence of Parkinson's disease in the elderly: the Rotterdam study. Neurology 1995;45:2143-2146.
21. Mayeux R, Marder K, Cote LJ, Denaro J, Hemenegildo N, Mejia H, Tang MX, Lantigua R, Wilder D, Gurland B: The frequency of idiopathic Parkinson's disease by age, ethnic group and sex in northern Manhattan, 1988-1993. Am J Epidemiol 1995;142:820-827.
22. Shavali S, Ren J, Ebadi M: Insulin-like growth factor-1 protects human dopaminergic SH-SY5Y cells from salsolinol-induced toxicity. Neurosci Lett 2003;340:79-82.
23. Hereñú CB, Cristina C, Rimoldi OJ, Becú-Villalobos D, Goya RG: Construction and use of an adenoviral vector to express transgenic insulin-like growth factor I in the arcuate nucleus and substantia nigra of young and old rats (abstract). 12th International Congress of Endocrinology, Lisbon, 2004.
24. Hereñú CB, Cristina C, Rimoldi OJ, Becú D, Zucolilli G, Portiansky E, Goya RG: IGF-I gene therapy in the brain of senile rats with dopaminergic neurodegeneration (abstract). Invited Symposium, 18th World Congress of Gerontology, Rio de Janeiro, 2005.
25. Hu N, Gutsmann A, Herbert DC, Bradley A, Lee WH, Lee EY: Heterozygous Rb-1 delta 20/+mice are predisposed to tumors of the pituitary gland with a nearly complete penetrance. Oncogene 1994;9:1021-1029.
26. +/- mice. Nature Med 1996;2:1316-1321.
27. Windeatt S, Southgate TD, Dewey RA, Bolognani F, Perone MJ, Larregina AT, Maleniak TC, Morris ID, Goya RG, Klatzmann D, Lowenstein PR, Castro MG: Adenovirus-mediated herpes simplex virus type-1 thymidine kinase gene therapy suppresses oestrogen-induced pituitary prolactinomas. J Clin Endocrinol Metab 2000;85:1296-1305.