A new approach to the synthesis of highly substituted 3-pyrrolin-2-ones

Synthesis

Volumn , Issue 12, 2006, Pages 2019-2030

  Arcadi, Antonio ^a   Marinelli, Fabio ^a   Rossi, Leucio ^a   Verdecchia, Mirella ^a  

^a UNIVERSITY OF L'AQUILA   (Italy)

Author keywords

3 pyrrolin 2 ones; Cyclizations; Lactams; Palladium; Propargylamines

Indexed keywords

AMINES; CARBONATES; SUBSTITUTION REACTIONS; SYNTHESIS (CHEMICAL);

3-PYRROLIN-2-ONES; CYCLIZATIONS; LACTAMS; PROPARGYLAMINES;

KETONES;

1 BENZYL 4 (2 CHLOROBENZYL) 5 ETHYL 5 METHYL 2 OXO 2,5 DIHYDRO 1H PYRROLE 3 CARBOXYLIC ACID ETHYL ESTER; 1 BENZYL 4 (3 CYANOBENZYL) 5,5 DIMETHYL 2 OXO 2,5 DIHYDRO 1H PYRROLE 3 CARBOXYLIC ACID ETHYL ESTER; 1 BENZYL 4 (3 METHOXYCARBONYLBENZYL) 5,5 DIMETHYL 2 OXO 2,5 DIHYDRO 1H PYRROLE 3 CARBOXYLIC ACID ETHYL ESTER; 1 BENZYL 4 (3 TRIFLUOROMETHYLBENZYL) 5,5 DIMETHYL 2 OXO 2,5 DIHYDRO 1H PYRROLE 3 CARBOXYLIC ACID ETHYL ESTER; 1 BENZYL 5 ETHYL 4 (3 METHOXYCARBONYLBENZYL) 5 METHYL 2 OXO 2,5 DIHYDRO 1H PYRROLE 3 CARBOXYLIC ACID ETHYL ESTER; 1 BENZYL 5,5 DIMETHYL 2 OXO 4 PYRIDIN 3 YLMETHYL 2,5 DIHYDRO 1H PYRROLE 3 CARBOXYLIC ACID ETHYL ESTER; 3 [3 [BENZYL(2 ETHOXYCARBONYLACETYL)AMINO] 3 METHYLBUT 1 YNYL]BENZOIC ACID METHYL ESTER; 3 [3 [BENZYL(2 ETHOXYCARBONYLACETYL)AMINO] 3 METHYLPENT 1 YNYL]BENZOIC ACID METHYL ESTER; 3 PYRROLIN 2 ONE DERIVATIVE; 4 (4 ACETYLBENZYL) 1 BENZYL 5 ETHYL 5 METHYL 2 OXO 2,5 DIHYDRO 1H PYRROLE 3 CARBOXYLIC ACID ETHYL ESTER; 4 [1 (2 ETHOXYCARBONYLACETYLAMINO)CYCLOHEXYLETHYNYL]BENZOIC ACID METHYL ESTER; AMIDE; CARBONIC ACID; N [1 (3 TRIFLUOROMETHYLPHENYLETHYNYL)CYCLOHEXYL]MALONAMIC ACID ETHYL ESTER; N [1 (4 ACETYLPHENYLETHYNYL)CYCLOHEXYL]MALONAMIC ACID ETHYL ESTER; N [2 (3,4 DIMETHOXYPHENYL)ETHYL] N (1,1 DIMETHYL 3 NAPHTHALEN 1 YLPROP 2 YNYL)MALONAMIC ACID ETHYL ESTER; N [2 (3,4 DIMETHOXYPHENYL)ETHYL] N (1,1 DIMETHYL 3 THIOPHEN 1 YLPROP 2 YNYL)MALONAMIC ACID ETHYL ESTER; N [3 (3 TRIFLUOROMETHYLPHENYL) 1,1 DIMETHYLPROP 2 YNYL] N [2 (3,4 DIMETHOXYPHENYL)ETHYL]MALONAMIC ACID ETHYL ESTER; N [3 (4 ACETYLPHENYL) 1 ETHYL 1 METHYLPROP 2 YNYL] N BENZYL MALONAMIC ACID ETHYL ESTER; N [3 (4 FLUOROPHENYL) 1,1 DIMETHYLPROP 2 YNYL] N [2 (3,4 DIMETHOXYPHENYL)ETHYL]MALONAMIC ACID ETHYL ESTER; N BENZYL N (1,1 DIMETHYL 3 PYRIDIN 3 YLPROP 2 YNYL)MALONAMIC ACID ETHYL ESTER; N BENZYL N [1 ETHYL 3 (4 METHANESULFONYLPHENYL) 1 METHYL PROP 2 YNYL]MALONAMIC ACID ETHYL ESTER; N BENZYL N [3 (2 CHLOROPHENYL) 1 ETHYL 1 METHYLPROP 2 YNYL]MALONAMIC ACID ETHYL ESTER; N BENZYL N [3 (3 CYANOPHENYL) 1,1 DIMETHYLPROP 2 YNYL]MALONAMIC ACID ETHYL ESTER; PYRROLINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CYCLIZATION; DRUG ISOLATION; DRUG STRUCTURE; DRUG SYNTHESIS;

EID: 33745761783     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-942393     Document Type: Article

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