Different responses of rat cerebellar Purkinje cells and Golgi cells evoked by widespread convergent sensory inputs

Journal of Physiology

Volumn 574, Issue 2, 2006, Pages 491-507

  Holtzman, Tahl ^a   Rajapaksa, Thimali ^a   Mostofi, Abteen ^a   Edgley, Steve A ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BRAIN NERVE CELL; CELL LABELING; CEREBELLUM CORTEX; CONTROLLED STUDY; EVOKED CORTICAL RESPONSE; FEEDBACK SYSTEM; IN VIVO STUDY; LATENT PERIOD; NERVE CELL STIMULATION; NEUROMODULATION; NEUROTRANSMISSION; NONHUMAN; PRIORITY JOURNAL; PURKINJE CELL; RAT; SENSORY NERVE; SENSORY STIMULATION; SPIKE WAVE; TACTILE STIMULATION; TRIGEMINAL NERVE; ADULT; ANIMAL TISSUE; BRAIN DEPTH STIMULATION; CELL FUNCTION; CEREBELLUM CELL; CEREBRAL CRUS; ELECTROPHYSIOLOGICAL PROCEDURES; EVOKED RESPONSE; FIRING RATE; GOLGI COMPLEX; RECEPTIVE FIELD;

ACTION POTENTIALS; ANIMALS; CEREBELLUM; EVOKED POTENTIALS, SOMATOSENSORY; NEURAL CONDUCTION; NEURONAL PLASTICITY; NEURONS, AFFERENT; PERIPHERAL NERVOUS SYSTEM; PURKINJE CELLS; RATS; RATS, INBRED STRAINS; RATS, WISTAR; SYNAPTIC TRANSMISSION;

EID: 33745752259     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2006.108282     Document Type: Article

References (54)

1. Albus JS (1971). A theory of cerebellar function. Math Biosci 10, 25-61.
2. Armstrong DM & Drew T (1980). Responses in the posterior lobe of the rat cerebellum to electrical stimulation of cutaneous afferents to the snout. J Physiol 309, 357-374.
3. Arshavsky YI, Gelfand IM & Orlovsky GN (1986). Cerebellum and Rhythmical Movements. Studies in Brain Function, vol. 13. Springer, Berlin.
4. Atkins MJ, Van Alphen AM & Simpson JI (1997). Characteristics of putative Golgi cells in the rabbit cerebellar flocculus. Abstr Soc Neurosci 23, 1287.
5. Baker SN, Philbin N, Spinks R, Pinches EM, Wolpert DM, MacManus DG, Pauluis Q & Lemon RN (1999). Multiple single unit recording in the cortex of monkeys using independently moveable microelectrodes. J Neurosci Methods 94, 5-17.
6. Bloedel JR & Courvile J (1981). Cerebellar afferent systems. In Handbook of Physiology, The Nervous System, Part 2, Motor Control, ed. Brookhart J, Mountcastle V, Brookes V & Geiger S pp. 735-830. American Physiological Society, Bethesda, MD.
7. Bower JM & Woolston DC (1983). Congruence of spatial organization of tactile projections to granule cell and Purkinje cell layers of cerebellar hemispheres of the albino rat: Vertical organization of cerebellar cortex. J Neurophysiol 49, 745-766.
8. Brown IE & Bower JM (2001). Congruence of mossy fiber and climbing fiber tactile projections in the lateral hemispheres of the rat cerebellum. J Comp Neurol 429, 59-70.
9. Carta M, Mameli M & Valenzuela CF (2004). Alcohol enhances GABAergic transmission to cerebellar granule cells via an increase in Golgi cell excitability. J Neurosci 24, 3746-3751.
10. Clendenin M, Ekerot CF & Oscarsson O (1975). The lateral reticular nucleus in the cat. IV. Activation from dorsal funiculus and trigeminal afferents. Exp Brain Res 24, 131-144.
11. Davey NJ, Ellaway PH & Stein RB (1986). Statistical limits for detecting change in the cumulative sum derivative of the peristimulus time histogram. J Neurosci Methods 17, 153-166.
12. De Schutter E, Vos B & Maex R (2000). The function of cerebellar Golgi cells revisited. Prog Brain Res 124, 81-93.
13. Dean I, Robertson SJ & Edwards FA (2003). Serotonin drives a novel GABAergic synaptic current recorded in rat cerebellar Purkinje cells: A Lugaro cell to Purkinje cell synapse. J Neurosci 23, 4457-4469.
14. Dieudonné S (1995). Glycinergic synaptic currents in Golgi cells of the rat cerebellum. Proc Natl Acad Sci U S A 92, 1441-1445.
15. Dieudonné S (1998). Submillisecond kinetics and low efficacy of parallel fibre-Golgi cell synaptic currents in the rat cerebellum. J Physiol 510, 845-866.
16. DieudonnéS & Dumoulin A (2000). Serotonin-driven long-range inhibitory connections in the cerebellar cortex. J Neurosci 20, 1837-1848.
17. Dumoulin A, Triller A & DieudonnéS (2001). IPSC kinetics at identified GABAergic and mixed GABAergic and glycinergic synapses onto cerebellar Golgi cells. J Neurosci 21, 6045-6057.
18. Eccles JC, Faber DS, Murphy JT, Sabah NH & Taborikova H (1971). Investigations on integration of mossy fiber inputs to Purkyne cells in the anterior lobe. Exp Brain Res 13, 54-77.
19. Eccles JC, Llinas RR & Sasaki K (1966). The mossy fibre-granule cell relay of the cerebellum and its inhibitory control by Golgi cells. Exp Brain Res 1, 82-101.
20. Eckhorn R & Thomas U (1993). A new method for the insertion of multiple microprobes into neural and muscular tissue, including fiber electrodes, fine wires, needles and microsensors. J Neurosci Methods 49, 175-179.
21. Edgley SA & Lidierth M (1987). The discharges of cerebellar Golgi cells during locomotion in the cat. J Physiol 392, 315-332.
22. Ekerot CF & Jorntell H (2001). Parallel fibre receptive fields of Purkinje cells and interneurons are climbing fibre-specific. Eur J Neurosci 13, 1303-1310.
23. Ekerot CF & Jorntell H (2003). Synaptic input to cerebellar Lugaro and Golgi cells studied with whole cell recording in vivo. Program No. 274.3 2003 Abstract Viewer/Itinerary Planner. Society for Neuroscience, Washington, DC.
24. Ekerot CF & Oscarsson O (1975). Inhibitory spinal paths to the lateral reticular nucleus. Brain Res 99, 157-161.
25. Isope P & Barbour B (2002). Properties of unitary granule cell →Purkinje cell synapses in adult rat cerebellar slices. J Neurosci 22, 9668-9678.
26. Ito M (1984). The Cerebellum and Neural Control. Raven Press, New York.
27. Keating JG & Thach WT (1995). Nonclock behavior of inferior olive neurons: Interspike interval of Purkinje cell complex spike discharge in the awake behaving monkey is random. J Neurophysiol 73, 1329-1340.
28. Kolb FP, Arnold G, Lerch R, Straka H & J (1997). Spatial distribution of field potential profiles in the cat cerebellar cortex evoked by peripheral and central inputs. Neuroscience 81, 1155-1181.
29. Laine J & Axelrad H (1998). Lugaro cells target basket and stellate cells in the cerebellar cortex. Neuroreport 9, 2399-2403.
30. Lang EJ, Sugihara I, Welsh JP & Llinas R (1999). Patterns of spontaneous Purkinje cell complex spike activity in the awake rat. J Neurosci 19, 2728-2739.
31. V, Mehta SB, Kleinfeld D & Tsien R (2003). Reversing cerebellar long-term depression. Proc Natl Acad Sci U S A 100, 15989-15993.
32. Llinas R & Sasaki K (1989). The functional organization of the olivo-cerebellar system as examined by multiple Purkinje cell recordings. Eur J Neurosci 1, 587-602.
33. Maex R & De Schutter E (1998). Synchronization of Golgi and granule cell firing in a detailed network model of the cerebellar granule cell layer. J Neurophysiol 80, 2521-2537.
34. Marr D (1969). A theory of cerebellar cortex. J Physiol 202, 437-470.
35. Miles FA, Fuller JH, Braitman DJ & Dow BM (1980). Long-term adaptive changes in primate vestibuloocular reflex. III. Electrophysiological observations in flocculus of normal monkeys. J Neurophysiol 43, 1437-1476.
36. Mitchell SJ & Silver RA (2000). GABA spillover from single inhibitory axons suppresses low-frequency excitatory transmission at the cerebellar glomerulus. J Neurosci 20, 8651-8658.
37. Neki A, Ohishi H, Kaneko T, Shigemoto R, Nakanishi S & Mizuno N (1996). Metabotropic glutamate receptors mGluR2 and mGluR5 are expressed in two non-overlapping populations of Golgi cells in the rat cerebellum. Neuroscience 75, 815-826.
38. Oscarsson O (1973). Functional organisation of spinocerebellar paths. In Handbook of Sensory Physiology, vol. II, Somatosensory System, ed. Iggo A, pp. 339-380, Springer-Verlag, New York.
39. Palay SL & Chan-Palay V (1974). Cerebellar Cortex: Cytology and Organisation. Springer Verlag, New York.
40. Pinault D (1996). A novel single-cell staining procedure performed in vivo under electrophysiological control: Morpho-functional features of juxtacellularly labeled thalamic cells and other central neurons with biocytin or Neurobiotin. J Neurosci Methods 65, 113-136.
41. Precht W & Llinas R (1969). Functional organisation of the vestibular afferents to the cerebellar cortex of the frog and cat. Exp Brain Res 9, 30-52.
42. Ramón y Cajal S (1911). Histology of the nervous system of man and the vertebrates, vol. I and II. Maloine, Paris.
43. a receptors and glomerular geometry. Neuron 20, 783-795.
44. Rowland NC & Jaeger D (2005). Coding of tactile response properties in the rat deepcerebellar nuclei. J Neurophysiol 94, 1236-1251.
45. Schulman JA & Bloom FE (1981). Golgi cells of the cerebellum are inhibited by inferior olive activity. Brain Res 210, 350-355.
46. Shambes GM, Gibson JM, Welker W (1978). Fractured somatotopy in granule cell tactile areas of rat cerebellar hemispheres revealed by micromapping. Brain Behav Evol 15(2), 94-140.
47. Simpson JI, Hulscher HC, Sabel-Goedknegt E & Ruigrok TJ (2005). Between in and out: Linking morphology and physiology of cerebellar cortical interneurons. Prog Brain Res 2005, 329-340.
48. Telgkamp P, Padgett DE, Ledoux VA, Woolley CS & Raman IM (2004). Maintenance of high-frequency transmission at Purkinje to cerebellar nuclear synapses by spillover from boutons with multiple release sites. Neuron 41, 113-126.
49. Van Kan PL & Gibson AR (1993). Movement-related inputs to intermediate cerebellum of the monkey. J Neurophysiol 69, 74-94.
50. Volny-Luraghi A, Maex R, Vos B & De Schutter E (2002). Peripheral stimuli excite coronal beams of Golgi cells in rat cerebellar cortex. Neuroscience 113, 363-373.
51. Vos BP, Volny-Luraghi A & De Schutter E (1999). Cerebellar Golgi cells in the rat: Receptive fields and timing of responses to facial stimulation. Eur J Neurosci 11, 2621-2634.
52. Vos BP, Volny-Luraghi A, Maex R & De Schutter E (2000). Precise spike timing of tactile-evoked cerebellar Golgi cell responses: A reflection of combined mossy fiber and parallel fiber activation? Prog Brain Res 124, 95-106.
53. Watanabe D & Nakanishi S (2003). mGluR2 postsynaptically senses granule cell inputs at Golgi cell synapses. Neuron 39, 821-829.
54. Welsh JP, Lang EJ, Suglhara I & Llinas R (1995). Dynamic organization of motor control within the olivocerebellar system. Nature 374, 453-457.