The function of cerebellar Golgi cells revisited

Progress in Brain Research

Volumn 124, Issue , 2000, Pages 81-93

  De Schutter, Erik ^a   Vos, Bart ^a   Maex, Reinoud ^a  

^a UNIVERSITY OF ANTWERP   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CEREBELLUM; CONFERENCE PAPER; EVOKED RESPONSE; GRANULE CELL; MODEL; MOSSY FIBER; NONHUMAN; PRIORITY JOURNAL; RECEPTIVE FIELD;

EID: 0033852999     PISSN: 00796123     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (90)

1. Albus, J.S. (1971) A theory of cerebellar function. Math. Biosci., 10: 25-61.
2. Atkins, M.J., VanAlphen, A.M. and Simpson, J.I. (1997) Characteristics of putative Golgi cells in the rabbit cerebellar flocculus. Abstr. Soc. Neurosci., 23: 1287.
3. Batchelor, A.M. and Garthwaite, J. (1997) Frequency detection and temporally dispersed synaptic signal association through a metabotropic glutamate receptor pathway. Nature, 385: 74-78.
4. Bernard, C. and Axelrad, H. (1991) Propagation of parallel fiber volleys in the cerebellar cortex: a computer simulation. Brain Res., 565: 195-208.
5. Bower, J.M., Beerman, D.H., Gibson, J.M., Shambes, G.M. and Welker, W. (1981) Principles of organization of a cerebro-cerebellar circuit. Micromapping the projections from cerebral (SI) to cerebellar (granule cell layer) tactile areas of rats. Brain Behav. Evol., 18: 1-18.
6. Bower, J.M. and Kassel, J. (1990) Variability in tactile projection patterns to cerebellar folia crus IIA of the Norway rat. J. Comp. Neurol., 302: 768-778.
7. Bower, J.M. and Woolston, D.C. (1983) Congruence of spatial organization of tactile projections to granule cell and Purkinje cell layers of cerebellar hemispheres of the albino rat: vertical organization of cerebellar cortex. J. Neurophysiol., 49: 745-766.
8. Braitenberg, V., Heck, D. and Sultan, F. (1997) The detection and generation of sequences as a key to cerebellar function. Experiments and theory. Behav. Brain Sci., 20: 229-245.
9. A receptors. J. Physiol., 497: 753-759.
10. Brodai, P. and Bjaalie, J.G. (1997) Salient anatomic features of the cortico-ponto-cerebellar pathway. Prog. Brain Res., 14: 227-249.
11. Brorson, J.R., Manzolillo, P.A., Gibbons, S.J. and Miller, R.J. (1995) AMPA receptor desensitization predicts the selective vulnerability of cerebellar Purkinje cells to excitotoxicity. J. Neurosci., 15: 4515-4524.
12. Brumberg, J.C., Pinto, D.J. and Simons, D.J. (1996) Spatial gradients and inhibitory summation in the rat whisker barrel system. J. Neurophysiol., 76: 130-140.
13. Calabrese, R.L. and De Schutter, E. (1992) Motor pattern generating networks in invertebrates: modeling our way toward understanding. Trends Neurosci., 15: 439-445.
14. Chauvet, P. and Chauvet, G.A. (1995) Mathematical conditions for adaptive control in Marr's model of the sensorimotor system. Neur. Networks, 8: 693-706.
15. Cobb, S.R., Buhl, E.H., Halasy, K., Paulsen, O. and Somogyi, P. (1995) Synchronization of neuronal activity in hippocampus by individual GABAergic interneurons. Nature, 378: 75-78.
16. Cohen, D. and Yarom, Y. (1998) Patches of synchronized activity in the cerebellar cortex evoked by mossy-fiber stimulation: questioning the role of parallel fibers. Proc. Natl. Acad. Sci. USA, 98: 15032-15036.
17. Cohen, D. and Yarom, Y. (2000) Unravelling cerebellar circuitry: an optical imaging study. Prog. Brain Res., 124: 107-114.
18. D'Angelo, E., DeFilippi, G., Rossi, P. and Taglietti, V. (1995) Synaptic excitation of individual rat cerebellar granule cells in situ: evidence for the role of NMDA receptors. J. Physiol., 482: 397-413.
19. D'Angelo, E., Filippi, G.D., Rossi, P. and Taglietti, V. (1998) Ionic mechanism of electroresponsiveness in cerebellar granule cells implicates the action of a persistent sodium current. J. Neurophysiol., 80: 493-503.
20. De Schutter, E. (1995) Cerebellar long-term depression might normalize excitation of Purkinje cells: a hypothesis. Trends Neurosci., 18: 291-295.
21. De Schutter, E. (1998) Dendritic voltage and calcium-gated channels amplify the variability of postsynaptic responses in a Purkinje cell model. J. Neurophysiol., 80: 504-519.
22. De Schutter, E. and Bower, J.M. (1994a) An active membrane model of the cerebellar Purkinje cell.I. Simulation of current clamps in slice. J. Neurophysiol., 71: 375-400.
23. De Schutter, E. and Bower, J.M. (1994b) An active membrane model of the cerebellar Purkinje cell: II. Simulation of synaptic responses. J. Neurophysiol., 71: 401-419.
24. Dieudonné, S. (1995) Glycinergic synaptic currents in Golgi cells of the rat cerebellum. Proc. Natl. Acad. Sci. USA, 92: 1441-1445.
25. Dieudonné, S. (1998a). Etude fonctionelle de deux interneurones inhibiteurs du cortex cérébelleux: les cellules de Lugaro et de Golgi. Unpublished doctoral thesis, Université Pierre et Marie Curie, Paris VI.
26. Dieudonné, S. (1998b) Submillisecond kinetics and low efficacy of parallel fibre-Golgi cell synaptic currents in the rat cerebellum. J. Physiol., 510: 845-866.
27. Dykes, R.W., Landry, P., Metherate, R. and Hicks, T.P. (1984) Functional role of GABA in cat primary somatosensory cortex: shaping receptive fields of cortical neurons. J. Neurophysiol., 52: 1066-1093.
28. Eccles, J.C., Ito, M. and Szentagothai, J. (1967) The Cerebellum as a Neuronal Machine. Springer-Verlag, Berlin.
29. Eccles, J.C., Llinás, R.R. and Sasaki, K. (1966) The mossy fibre-granule cell relay of the cerebellum and its inhibitory control by Golgi cells. Exp. Brain Res., 1: 82-101.
30. Edgley, S.A. and Lidierth, M. (1987) The discharges of cerebellar Golgi cells during locomotion in the cat. J. Physiol., 392: 315-332.
31. Finch, E.A. and Augustine, G.J. (1998) Local calcium signalling by inositol-1,4,5-trisphosphate in Purkinje cell dendrites. Nature, 396: 753-756.
32. Freeman, W.J. (1972) Waves, pulses, and the theory of neural masses. In: R. Rosen and F.M. Snell (Eds), Progress in Theoretical Biology. (Vol. 2). Academic Press, New York, pp. 87-165.
33. Fu, Q.-G., Flament, D., Coltz, J.D. and Ebner, T.J. (1997) Relationship of cerebellar Purkinje cell simple spike discharge to movement kinetics in the monkey. J. Neurophysiol., 78: 478-491.
34. Fujita, M. (1982) Adaptive filter model of the cerebellum. Biol. Cybern., 45: 195-206.
35. Gundappa-Sulur, G., De Schutter, E. and Bower, J.M. (1999) The ascending granule cell axon: an important component of the cerebellar cortical circuitry. J. Comp. Neurol., 408: 580-596.
36. Hartmann, M.J. and Bower, J.M. (1998) Oscillatory activity in the cerebellar hemispheres of unrestrained rats. J. Neurophysiol., 80: 1598-1604.
37. Harvey, R.J. and Napper, R.M.A. (1991) Quantitative studies of the mammalian cerebellum. Prog. Neurobiol., 36: 437-463.
38. Hopfleld, J.J. (1995) Pattern recognition computation using action potential timing for stimulus representation. Nature, 376: 33-36.
39. Ito, M. (1984) The Cerebellum and Neural Control. Raven Press, New York.
40. Ivry, R. (1997) Cerebellar timing systems. In: J.D. Schmahmann (Ed.), The Cerebellum and Cognition. (Vol. 41). Academic Press, San Diego, pp. 556-573.
41. Jakab, R.I. and Hámori, J. (1988) Quantitative morphology and synaptology of cerebellar glomeruli in the rat. Anat. Embryol., 179: 81-88.
42. Kammen, D.M., Holmes, P.J. and Koch, C. (1989) Cortical architecture and oscillations in neuronal networks: Feedback versus local coupling. In: R.M.J. Cotterill (Ed.), Models of Brain Function. Cambridge University Press, Cambridge, pp. 273-284.
43. Keeler, J.D. (1990) A dynamical system view of cerebellar function. Physica D, 42: 396-410.
44. Koch, C. (1998) Biophysics of Computation: Information Processing in Single Neurons. Oxford University Press.
45. König, P. and Schulen, T.B. (1991) Stimulus-dependent assembly formation of oscillatory responses: I. Synchronization. Neural Comput., 3: 155-166.
46. Lytton, W. W. and Sejnowski, T.J. (1991) Simulations of cortical pyramidal neurons synchronized by inhibitory interneurons. J. Neurophysiol., 66: 1059-1079.
47. Maex, R. and De Schutter, E. (1998a). The critical synaptic number for rhythmogenesis and synchronization in a network model of the cerebellar granular layer. In: L. Niklasson, M. Boden and T. Ziemke (Eds), ICANN 98. Springer-Verlag, London, pp. 361-366.
48. Maex, R. and De Schutter, E. (1998b) Synchronization of Golgi and granule cell firing in a detailed network model of the cerebellar granule cell layer. J. Neurophysiol., 80: 2521-2537.
49. Maex, R. and De Schutter, E. (1999). An optimal connection radius for long-range synchronization. In: D. Willshaw (Ed.), ICANN 99, IEE Proceedings No. 470: 557-562.
50. Maex, R., Vos, B.P. and De Schutter, E. (1998) The height and width of central peaks on spike train cross-correlograms. Eur. J. Neurosci., Suppl. 10: 303.
51. Marder, E. and Calabrese, R.L. (1996) Principles of rhythmic motor pattern generation. Physiol. Rev., 76: 687-717.
52. Marr, D.A. (1969) A theory of cerebellar cortex. J. Physiol., 202: 437-470.
53. Meek, J. (1992) Why run parallel fibers parallel? Teleostean Purkinje cells as possible coincidence detectors, in a timing device subserving spatial coding of temporal differences. Neuroscience, 48: 249-283.
54. Mihailoff, G.A., Kosinski, R.J., Azizi, S.A., Lee, H.S. and Border, B.C. (1992) The expanding role of the basilar pontine nuclei as a source of cerebellar afferents. In: R.R. Llinás, and C. Sotelo (Eds), The Cerebellum Revisited. Springer-Verlag, Berlin, pp. 135-164.
55. Moore, J.W., Desmond, J.E. and Berthier, N.E. (1989) Adaptively timed conditioned responses and the cerebellum: a neural network approach. Biol. Cybern., 62: 17-28.
56. Morissette, J. and Bower, J.M. (1996) Contribution of somatosensory cortex to responses in the rat cerebellar cortex granule cell layer following peripheral tactile stimulation. Exp Brain Res, 109, 240-250.
57. Mountcastle, V.B., Davies, P.W. and Berman, A.L. (1957) Response properties of neurons of cat's somatic sensory cortex to peripheral stimuli. J Neurophysiol, 20, 374-407.
58. Mugnaini, E. (1983) The length of cerebellar parallel fibers in chicken and rhesus monkey. J. Comp. Neurol., 220: 7-15.
59. Murphy, J.T. and Sabah, N.H. (1971) Cerebellar Purkinje cell responses to afferent inputs.II. Mossy fiber activation. Brain Res., 25: 469-482.
60. Nicolelis, M.A.L. and Chapin, J.K. (1994) Spatiotemporal structure of somatosensory responses of many-neuron ensembles in the rat ventral posterio medial nucleus of the thalamus. J. Neurosci., 14: 3511-3532.
61. Nicolelis, M.A.L., Ghazanfar, A.A., Faggin, B.M., Votaw, S. and Oliveira, L.M.O. (1997) Reconstructing the engram: simultaneous, multisite, many single neuron recordings. Neuron, 18:529-537.
62. A receptors to synaptic and extrasynaptic membranes of cerebellar granule cells. J. Neurosci., 18: 1693-1703.
63. Palkovits, M., Magyar, P. and Szentagothai, J. (1971) Quantitative histological analysis of the cerebellar cortex in the cat. II. Cell numbers and densities in the granular layer. Brain Res., 32: 15-30.
64. Peelers, R.R., Verhoye, M., Vos, B.P., Van Dyck, D., Van Der Linden, A. and De Schutter, E. (1999) A patchy horizontal organization of the somatosensory activation of the rat cerebellum demonstrated by functional MRI. Eur. J. Neurosci., 11: 2720-2730.
65. Pellerin, J.-P. and Lamarre, Y. (1997) Local field potential oscillations in primate cerebellar cortex during voluntary movement. J. Neurophysiol., 78: 3502-3507.
66. Pellionisz, A. and Szentagothai, J. (1973) Dynamic single unit simulation of a realistic cerebellar network model. Brain Res., 49: 83-99.
67. Pichitpornchai, C., Rawson, J.A. and Rees, S. (1994) Morphology of parallel fibers in the cerebellar cortex of the rat: an experimental light and electron microscopic study with biocytin. J. Comp. Neurol., 342: 206-220.
68. Raymond, J.L., Lisberger, S.G. and Mauk, M.D. (1996) The cerebellum: a neuronal learning machine? Science, 272: 1126-1131.
69. Regan, L.J. (1991) Voltage-dependent calcium currents in Purkinje cells from rat cerebellar vermis. J. Neurosci., 11: 2259-2269.
70. Rieke, F., Warland, D., de Ruyter van Steveninck, R.R. and Bialek, W. (1997) Spikes. Exploring the Neural Code. The MIT Press, Cambridge, MA.
71. A receptors and glomerular geometry. Neuron, 20: 783-795.
72. Santamaria, F., Jaeger, D., Bower, J.M. and De Schutter, E. (2000) Dendritic temporal integration properties of a Purkinje cell are modulated by background activity: A modeling study, in preparation.
73. Schweighofer, N., Spoelstra, J., Arbib, M.A. and Kawato, M. (1998) Role of the cerebellum in reaching movements in humans. II. A neural model of the intermediate cerebellum. Eur. J. Neurosci., 10: 95-105.
74. Shambes, G.M., Gibson, J.M. and Welker, W. (1978) Fractured somatotopy in granule cell tactile areas of rat cerebellar hemispheres revealed by micromapping. Brain Behav. Evol., 15: 94-140.
75. Simpson, J.I., Vandersteen, J., Tan, J., Graf, W. and Leonard, C.S. (1989) Representations of ocular rotations in the cerebellar flocculus of the rabbit. Prog. Brain Res., 80: 213-223.
76. Steuber, V. and Willshaw, D.J. (1999) Adaptive leaky integrator models of cerebellar Purkinje cells can learn the clustering of temporal patterns. Neurocomputing, 26: 271-276.
77. Strahlendorf, J.C., Brandon, T., Miles, R. and Strahlendorf, H.K. (1998) AMPA receptor-mediated alterations of intracellular calcium homeostasis in rat cerebellar Purkinje cells in vitro: correlates to dark cell degeneration. Neurochem. Res., 23: 1355-1362.
78. Stuart, G. and Hausser, M. (1994) Initiation and spread of sodium action potentials in cerebellar Purkinje cells. Neuron, 13: 703-712.
79. Tempia, F., Miniaci, M.C., Anchisi, D. and Strata, P. (1998) Postsynaptic current mediated by metabotropic glutamate receptors in cerebellar Purkinje cells. J. Neurophysiol., 80: 520-528.
80. Thach, W.T. (1998) What is the role of the cerebellum in motor learning and cognition. Trends Cogn. Sci., 2: 331-337.
81. Usowicz, M.M., Sugimori, M., Cherksey, B. and Llinás, R.R. (1992) Characterization of P-type calcium channels in cerebellar Purkinje cells. Abstr. Soc. Neurosci., 18: 974-974.
82. Van Kan, P.L.E., Gibson, A.R. and Houk, J.C. (1993) Movement-related inputs to intermediate cerebellum of the monkey. J. Neurophysiol., 69: 74-94.
83. Volny-Luraghi, A., De Schutter, E. and Vos, B.P. (1999) Responses of cerebellar Golgi cells to tactile stimuli of different sizes. Abstr. Soc. Neurosci., 25: 941.
84. Voogd, J. and Glickstein, M. (1998) The anatomy of the cerebellum. Trends Neurosci., 21: 370-375.
85. Vos, B.P., Maex, R., Volny-Luraghi, A. and De Schutter, E. (1999a) Parallel fibers synchronize spontaneous activity in cerebellar Golgi cells. J. Neurosci., 19: RC6: 1-5.
86. Vos, B.P., Volny-Luraghi, A. and De Schutter, E. (1999b) Cerebellar Golgi cells in the rat: receptive fields and timing of responses to facial stimulation. Eur. J. Neurosci., 11: 2621-2634.
87. Vos, B.P., Volny-Luraghi, A., Maex, R. and De Schutter, E. (2000) Precise spike timing of tactile-evoked cerebellar Golgi cell responses: a reflection of combined mossy fiber and parallel fiber activation? Prog. Brain Res., 124: 95-105.
88. Vranesic, L, Iijima, T., Ichikawa, M., Matsumoto, G. and Knöpfel, T. (1994) Signal transmission in the parallel fiber Purkinje cell system visualized by high-resolution imaging. Proc. Natl. Acad. Sci. USA, 91: 13014-13017.
89. A receptor-mediated currents in granule cells of postnatal rat cerebellum. Eur. J. Neurosci., 9: 533-548.
90. Welsh, J.P., Lang, E.J., Sugihara, I. and Llinás, R. (1995) Dynamic organization of motor control within the olivocerebellar system. Nature, 374: 453-457.