-
1
-
-
1342265798
-
Phase II trial of cisplatin plus temozolomide, in recurrent and progressive malignant glioma patients
-
Silvani A, Eoli M, Salmaggi A, Lamperti E, Maccagnano E, Broggi G, Boiardi A (2004) Phase II trial of cisplatin plus temozolomide, in recurrent and progressive malignant glioma patients. J Neurooncol 66: 203-208
-
(2004)
J Neurooncol
, vol.66
, pp. 203-208
-
-
Silvani, A.1
Eoli, M.2
Salmaggi, A.3
Lamperti, E.4
Maccagnano, E.5
Broggi, G.6
Boiardi, A.7
-
2
-
-
1842431900
-
The effect of sequential radiochemotherapy in preirradiated malignant gliomas in a phase II study
-
Schafer U, Micke O, Schuller P, Schuck A, Willich N (2004) The effect of sequential radiochemotherapy in preirradiated malignant gliomas in a phase II study. J Neurooncol 67: 233-239
-
(2004)
J Neurooncol
, vol.67
, pp. 233-239
-
-
Schafer, U.1
Micke, O.2
Schuller, P.3
Schuck, A.4
Willich, N.5
-
3
-
-
9144254455
-
Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study
-
Prados MD, Yung WK, Fine HA, Greenberg HS, Junck L, Chang SM, Nicholas MK, Robins HI, Mehta MP, Fink KL, Jaeckle KA, Kuhn J, Hess KR, Schold SC Jr (2004) Phase 2 study of BCNU and temozolomide for recurrent glioblastoma multiforme: North American Brain Tumor Consortium study. Neuro-oncol 6: 33-37
-
(2004)
Neuro-oncol
, vol.6
, pp. 33-37
-
-
Prados, M.D.1
Yung, W.K.2
Fine, H.A.3
Greenberg, H.S.4
Junck, L.5
Chang, S.M.6
Nicholas, M.K.7
Robins, H.I.8
Mehta, M.P.9
Fink, K.L.10
Jaeckle, K.A.11
Kuhn, J.12
Hess, K.R.13
Schold Jr., S.C.14
-
4
-
-
0842284060
-
Temozolomide in combination with irinotecan for treatment of recurrent malignant glioma
-
Gruber ML, Buster WP (2004) Temozolomide in combination with irinotecan for treatment of recurrent malignant glioma. Am J Clin Oncol 27: 33-38
-
(2004)
Am J Clin Oncol
, vol.27
, pp. 33-38
-
-
Gruber, M.L.1
Buster, W.P.2
-
5
-
-
12144286418
-
Temozolomide as first-line agent in treating high-grade glioraas: Phase II study
-
Chibbaro S, Benvenuti L, Caprio A, Carnesecchi S, Pulera F, Faggionato F, Serino D, Galli C, Andreuccetti M, Buxton N, Gagliardi R (2004) Temozolomide as first-line agent in treating high-grade glioraas: phase II study. J Neurooncol 67: 77-81
-
(2004)
J Neurooncol
, vol.67
, pp. 77-81
-
-
Chibbaro, S.1
Benvenuti, L.2
Caprio, A.3
Carnesecchi, S.4
Pulera, F.5
Faggionato, F.6
Serino, D.7
Galli, C.8
Andreuccetti, M.9
Buxton, N.10
Gagliardi, R.11
-
6
-
-
11144355301
-
Phase II study of neoadjuvant 1, 3-bis (2-chloroethyl)-1-nitrosourea and temozolomide for newly diagnosed anaplastic glioma: A North American Brain Tumor Consortium Trial
-
Chang SM, Prados MD, Yung WK, Fine H, Junck L, Greenberg H, Robins HI, Mehta M, Fink KL, Jaeckle KA, Kuhn J, Hess K, Schold C (2004) Phase II study of neoadjuvant 1, 3-bis (2-chloroethyl)-1-nitrosourea and temozolomide for newly diagnosed anaplastic glioma: a North American Brain Tumor Consortium Trial. Cancer 100: 1712-1716
-
(2004)
Cancer
, vol.100
, pp. 1712-1716
-
-
Chang, S.M.1
Prados, M.D.2
Yung, W.K.3
Fine, H.4
Junck, L.5
Greenberg, H.6
Robins, H.I.7
Mehta, M.8
Fink, K.L.9
Jaeckle, K.A.10
Kuhn, J.11
Hess, K.12
Schold, C.13
-
7
-
-
2442717967
-
First-line chemotherapy with cisplatin plus fractionated temozolomide in recurrent glioblastoma multiforme: A phase II study of the Gruppo Italiano Cooperative di Neuro-Oncologia
-
Brandes AA, Basso U, Reni M, Vastola F, Tosoni A, Cavallo G, Scopece L, Ferreri AJ, Panucci MG, Monfardini S, Ermani M (2004) First-line chemotherapy with cisplatin plus fractionated temozolomide in recurrent glioblastoma multiforme: a phase II study of the Gruppo Italiano Cooperative di Neuro-Oncologia. J Clin Oncol 22: 1598-1604
-
(2004)
J Clin Oncol
, vol.22
, pp. 1598-1604
-
-
Brandes, A.A.1
Basso, U.2
Reni, M.3
Vastola, F.4
Tosoni, A.5
Cavallo, G.6
Scopece, L.7
Ferreri, A.J.8
Panucci, M.G.9
Monfardini, S.10
Ermani, M.11
-
8
-
-
1842536794
-
Combined thalidomide and temozolomide treatment in patients with glioblastoma multiforme
-
Baumann F, Bjeljac M, Kollias SS, Baumert BG, Brandner S, Rousson V, Yonekawa Y, Bernays RL (2004) Combined thalidomide and temozolomide treatment in patients with glioblastoma multiforme. J Neurooncol 67: 191-200
-
(2004)
J Neurooncol
, vol.67
, pp. 191-200
-
-
Baumann, F.1
Bjeljac, M.2
Kollias, S.S.3
Baumert, B.G.4
Brandner, S.5
Rousson, V.6
Yonekawa, Y.7
Bernays, R.L.8
-
9
-
-
0141615682
-
Survival of patients with recurrent malignant glioma treated with temozolomide: A retrospective observational study
-
Trippoli S, Pelagotti F, Messori A, Vacca F, Vaiani M, Maltoni S (2003) Survival of patients with recurrent malignant glioma treated with temozolomide: a retrospective observational study. Drugs R D 4: 285-291
-
(2003)
Drugs R D
, vol.4
, pp. 285-291
-
-
Trippoli, S.1
Pelagotti, F.2
Messori, A.3
Vacca, F.4
Vaiani, M.5
Maltoni, S.6
-
10
-
-
4444306160
-
Temozolomide for the treatment of recurrent supratentorial glioma: Results of a compassionate use program in Belgium
-
Everaert E, Neyns B, Joosens E, Strauven T, Branle F, Menten J (2004) Temozolomide for the treatment of recurrent supratentorial glioma: results of a compassionate use program in Belgium. J Neurooncol 70: 37-48
-
(2004)
J Neurooncol
, vol.70
, pp. 37-48
-
-
Everaert, E.1
Neyns, B.2
Joosens, E.3
Strauven, T.4
Branle, F.5
Menten, J.6
-
11
-
-
20044366163
-
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
-
Stupp R, Mason WP, van den Bent MJ, Weller M, Fisher B, Taphoorn MJ, Belanger K, Brandes AA, Marosi C, Bogdahn U, Curschmann J, Janzer RC, Ludwin SK, Gorlia T, Allgeier A, Lacombe D, Caimcross JG, Eisenhauer E, Mirimanoff RO (2005) Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. N Engl J Med 352: 987-996
-
(2005)
N Engl J Med
, vol.352
, pp. 987-996
-
-
Stupp, R.1
Mason, W.P.2
Van Den Bent, M.J.3
Weller, M.4
Fisher, B.5
Taphoorn, M.J.6
Belanger, K.7
Brandes, A.A.8
Marosi, C.9
Bogdahn, U.10
Curschmann, J.11
Janzer, R.C.12
Ludwin, S.K.13
Gorlia, T.14
Allgeier, A.15
Lacombe, D.16
Caimcross, J.G.17
Eisenhauer, E.18
Mirimanoff, R.O.19
-
12
-
-
0033897173
-
A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse
-
Yung WK, Albright RE, Olson J, Fredericks R, Fink K, Prados MD, Brada M, Spence A, Hohl RJ, Shapiro W, Glantz M, Greenberg H, Selker RG, Vick NA, Rampling R, Friedman H, Phillips P, Bruner J, Yue N, Osoba D, Zaknoen S, Levin VA (2000) A phase II study of temozolomide vs. procarbazine in patients with glioblastoma multiforme at first relapse. Br J Cancer 83: 588-593
-
(2000)
Br J Cancer
, vol.83
, pp. 588-593
-
-
Yung, W.K.1
Albright, R.E.2
Olson, J.3
Fredericks, R.4
Fink, K.5
Prados, M.D.6
Brada, M.7
Spence, A.8
Hohl, R.J.9
Shapiro, W.10
Glantz, M.11
Greenberg, H.12
Selker, R.G.13
Vick, N.A.14
Rampling, R.15
Friedman, H.16
Phillips, P.17
Bruner, J.18
Yue, N.19
Osoba, D.20
Zaknoen, S.21
Levin, V.A.22
more..
-
13
-
-
0029664326
-
O6-benzylguanine enhances the sensitivity of a glioma xenograft with low O6-alkylguanine-DNA alkyltransferase activity to temozolomide and BCNU
-
Wedge SR, Newlands ES (1996) O6-benzylguanine enhances the sensitivity of a glioma xenograft with low O6-alkylguanine-DNA alkyltransferase activity to temozolomide and BCNU. Br J Cancer 73: 1049-1052
-
(1996)
Br J Cancer
, vol.73
, pp. 1049-1052
-
-
Wedge, S.R.1
Newlands, E.S.2
-
14
-
-
0032435612
-
DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma
-
Friedman HS, McLendon RE, Kerby T, Dugan M, Bigner SH, Henry AJ, Ashley DM, Krischer J, Lovell S, Rasheed K, Marchev F, Seman AJ, Cokgor I, Rich J, Stewart E, Colvin OM, Provenzale JM, Bigner DD, Haglund MM, Friedman AH, Modrich PL (1998) DNA mismatch repair and O6-alkylguanine-DNA alkyltransferase analysis and response to Temodal in newly diagnosed malignant glioma. J Clin Oncol 16: 3851-3857
-
(1998)
J Clin Oncol
, vol.16
, pp. 3851-3857
-
-
Friedman, H.S.1
McLendon, R.E.2
Kerby, T.3
Dugan, M.4
Bigner, S.H.5
Henry, A.J.6
Ashley, D.M.7
Krischer, J.8
Lovell, S.9
Rasheed, K.10
Marchev, F.11
Seman, A.J.12
Cokgor, I.13
Rich, J.14
Stewart, E.15
Colvin, O.M.16
Provenzale, J.M.17
Bigner, D.D.18
Haglund, M.M.19
Friedman, A.H.20
Modrich, P.L.21
more..
-
15
-
-
0037692954
-
Marked inactivation of O6-alkylguanine-DNA alkyltransferase activity with protracted temozolomide schedules
-
Tolcher AW, Gerson SL, Denis L, Geyer C, Hammond LA, Patnaik A, Goetz AD, Schwartz G, Edwards T, Reyderman L, Statkevich P, Cutler DL, Rowinsky EK (2003) Marked inactivation of O6-alkylguanine-DNA alkyltransferase activity with protracted temozolomide schedules. Br J Cancer 88: 1004-1011
-
(2003)
Br J Cancer
, vol.88
, pp. 1004-1011
-
-
Tolcher, A.W.1
Gerson, S.L.2
Denis, L.3
Geyer, C.4
Hammond, L.A.5
Patnaik, A.6
Goetz, A.D.7
Schwartz, G.8
Edwards, T.9
Reyderman, L.10
Statkevich, P.11
Cutler, D.L.12
Rowinsky, E.K.13
-
16
-
-
20044372154
-
MGMT gene silencing and benefit from temozolomide in glioblastoma
-
Hegi ME, Diserens AC, Gorlia T, Hamou MF, de Tribolet N, Weller M, Kros JM, Hainfellner JA, Mason W, Mariani L, Bromberg JE, Hau P, Mirimanoff RO, Cairncross JG, Janzer RC, Stupp R (2005) MGMT gene silencing and benefit from temozolomide in glioblastoma. N Engl J Med 352: 997-1003
-
(2005)
N Engl J Med
, vol.352
, pp. 997-1003
-
-
Hegi, M.E.1
Diserens, A.C.2
Gorlia, T.3
Hamou, M.F.4
De Tribolet, N.5
Weller, M.6
Kros, J.M.7
Hainfellner, J.A.8
Mason, W.9
Mariani, L.10
Bromberg, J.E.11
Hau, P.12
Mirimanoff, R.O.13
Cairncross, J.G.14
Janzer, R.C.15
Stupp, R.16
-
17
-
-
12144291692
-
Clinical trial substantiates the predictive value of O-6-methylguanine- DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide
-
Hegi ME, Diserens AC, Godard S, Dietrich PY, Regli L, Ostermann S, Otten P, Van Meile G, de Tribolet N, Stupp R (2004) Clinical trial substantiates the predictive value of O-6-methylguanine-DNA methyltransferase promoter methylation in glioblastoma patients treated with temozolomide. Clin Cancer Res 10: 1871-1874
-
(2004)
Clin Cancer Res
, vol.10
, pp. 1871-1874
-
-
Hegi, M.E.1
Diserens, A.C.2
Godard, S.3
Dietrich, P.Y.4
Regli, L.5
Ostermann, S.6
Otten, P.7
Van Meile, G.8
De Tribolet, N.9
Stupp, R.10
-
18
-
-
0033206868
-
Response and progression in recurrent malignant glioma
-
Hess KR, Wong ET, Jaeckle KA, Kyritsis AP, Levin VA, Prados MD, Yung WK (1999) Response and progression in recurrent malignant glioma. Neuro-oncol 1: 282-288
-
(1999)
Neuro-oncol
, vol.1
, pp. 282-288
-
-
Hess, K.R.1
Wong, E.T.2
Jaeckle, K.A.3
Kyritsis, A.P.4
Levin, V.A.5
Prados, M.D.6
Yung, W.K.7
-
19
-
-
0032767387
-
Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials
-
Wong ET, Hess KR, Gleason MJ, Jaeckle KA, Kyritsis AP, Prados MD, Levin VA, Yung WK (1999) Outcomes and prognostic factors in recurrent glioma patients enrolled onto phase II clinical trials. J Clin Oncol 17: 2572
-
(1999)
J Clin Oncol
, vol.17
, pp. 2572
-
-
Wong, E.T.1
Hess, K.R.2
Gleason, M.J.3
Jaeckle, K.A.4
Kyritsis, A.P.5
Prados, M.D.6
Levin, V.A.7
Yung, W.K.8
-
20
-
-
0035108398
-
Multicenter phase II trial of temozolomide in patients with glioblastoma multi-forme at first relapse
-
Brada M, Hoang-Xuan K, Rampling R, Dietrich PY, Dirix LY, Macdonald D, Heimans JJ, Zonnenberg BA, Bravo-Marques JM, Henriksson R, Stupp R, Yue N, Bruner J, Dugan M, Rao S, Zaknoen S (2001) Multicenter phase II trial of temozolomide in patients with glioblastoma multi-forme at first relapse. Ann Oncol 12: 259-266
-
(2001)
Ann Oncol
, vol.12
, pp. 259-266
-
-
Brada, M.1
Hoang-Xuan, K.2
Rampling, R.3
Dietrich, P.Y.4
Dirix, L.Y.5
Macdonald, D.6
Heimans, J.J.7
Zonnenberg, B.A.8
Bravo-Marques, J.M.9
Henriksson, R.10
Stupp, R.11
Yue, N.12
Bruner, J.13
Dugan, M.14
Rao, S.15
Zaknoen, S.16
-
22
-
-
0036499078
-
Phase II trial of temozolomide plus the matrix metalloproteinase inhibitor, marimastat, in recurrent and progressive glioblastoma multi-forme
-
Groves MD, Puduvalli VK, Hess KR, Jaeckle KA, Peterson P, Yung WK, Levin VA (2002) Phase II trial of temozolomide plus the matrix metalloproteinase inhibitor, marimastat, in recurrent and progressive glioblastoma multi-forme. J Clin Oncol 20: 1383-1388
-
(2002)
J Clin Oncol
, vol.20
, pp. 1383-1388
-
-
Groves, M.D.1
Puduvalli, V.K.2
Hess, K.R.3
Jaeckle, K.A.4
Peterson, P.5
Yung, W.K.6
Levin, V.A.7
-
23
-
-
0038149438
-
Phase II evaluation of temozolomide and 13-cis-retinoic acid for the treatment of recurrent and progressive malignant glioma: A North American Brain Tumor Consortium study
-
Jaeckle KA, Hess KR, Yung WK, Greenberg H, Fine H, Schiff D, Pollack IF, Kuhn J, Fink K, Mehta M, Cloughesy T, Nicholas MK, Chang S, Prados M (2003) Phase II evaluation of temozolomide and 13-cis-retinoic acid for the treatment of recurrent and progressive malignant glioma: a North American Brain Tumor Consortium study. J Clin Oncol 21: 2305-2311
-
(2003)
J Clin Oncol
, vol.21
, pp. 2305-2311
-
-
Jaeckle, K.A.1
Hess, K.R.2
Yung, W.K.3
Greenberg, H.4
Fine, H.5
Schiff, D.6
Pollack, I.F.7
Kuhn, J.8
Fink, K.9
Mehta, M.10
Cloughesy, T.11
Nicholas, M.K.12
Chang, S.13
Prados, M.14
-
24
-
-
19244369667
-
Survival improvement in patients with glioblastoma multiforme during the last 20 years in a single tertiary-care center
-
Fazeny-Dorner B, Gyries A, Rossler K, Ungersbock K, Czech T, Budinsky A, Killer M, Dieckmann K, Piribauer M, Baumgartner G, Prayer D, Veitl M, Muhm M, Marosi C (2003) Survival improvement in patients with glioblastoma multiforme during the last 20 years in a single tertiary-care center. Wien Klin Wochenschr 115: 389-397
-
(2003)
Wien Klin Wochenschr
, vol.115
, pp. 389-397
-
-
Fazeny-Dorner, B.1
Gyries, A.2
Rossler, K.3
Ungersbock, K.4
Czech, T.5
Budinsky, A.6
Killer, M.7
Dieckmann, K.8
Piribauer, M.9
Baumgartner, G.10
Prayer, D.11
Veitl, M.12
Muhm, M.13
Marosi, C.14
-
26
-
-
0032855728
-
Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse
-
Temodal Brain Tumor Group
-
Yung WK, Prados MD, Yaya-Tur R, Rosenfeld SS, Brada M, Friedman HS, Albright R, Olson J, Chang SM, O'Neill AM, Friedman AH, Brumer J, Yue N, Dugan M, Zaknoen S, Levin VA (1999) Multicenter phase II trial of temozolomide in patients with anaplastic astrocytoma or anaplastic oligoastrocytoma at first relapse. Temodal Brain Tumor Group. J Clin Oncol 17: 2762-2771
-
(1999)
J Clin Oncol
, vol.17
, pp. 2762-2771
-
-
Yung, W.K.1
Prados, M.D.2
Yaya-Tur, R.3
Rosenfeld, S.S.4
Brada, M.5
Friedman, H.S.6
Albright, R.7
Olson, J.8
Chang, S.M.9
O'Neill, A.M.10
Friedman, A.H.11
Brumer, J.12
Yue, N.13
Dugan, M.14
Zaknoen, S.15
Levin, V.A.16
-
27
-
-
28044460508
-
Health-related quality of life in patients with glioblastoma: A randomised controlled trial
-
Taphoorn MJ, Stupp R, Coens C, Osoba D, Kortmann R, van den Bent MJ, Mason W, Mirimanoff RO, Baumert BG, Eisenhauer E, Forsyth P, Bottomley A (2005) Health-related quality of life in patients with glioblastoma: a randomised controlled trial. Lancet Oncol 6: 937-944
-
(2005)
Lancet Oncol
, vol.6
, pp. 937-944
-
-
Taphoorn, M.J.1
Stupp, R.2
Coens, C.3
Osoba, D.4
Kortmann, R.5
Van Den Bent, M.J.6
Mason, W.7
Mirimanoff, R.O.8
Baumert, B.G.9
Eisenhauer, E.10
Forsyth, P.11
Bottomley, A.12
-
28
-
-
17944382261
-
Cost of temozolomide therapy and global care for recurrent malignant gliomas followed until death
-
Wasserfallen JB, Ostermann S, Leyvraz S, Stupp R (2005) Cost of temozolomide therapy and global care for recurrent malignant gliomas followed until death. Neuro-oncol 7: 189-195
-
(2005)
Neuro-oncol
, vol.7
, pp. 189-195
-
-
Wasserfallen, J.B.1
Ostermann, S.2
Leyvraz, S.3
Stupp, R.4
-
29
-
-
7044237227
-
Can we afford to add chemotherapy to radiotherapy for glioblastoma multi-forme? Cost-identification analysis of concomitant and adjuvant treatment with temozolomide until patient death
-
Wasserfallen JB, Ostermann S, Pica A, Mirimanoff RO, Leyvraz S, Villemure JG, Stupp R (2004) Can we afford to add chemotherapy to radiotherapy for glioblastoma multi-forme? Cost-identification analysis of concomitant and adjuvant treatment with temozolomide until patient death. Cancer 101: 2098-2105
-
(2004)
Cancer
, vol.101
, pp. 2098-2105
-
-
Wasserfallen, J.B.1
Ostermann, S.2
Pica, A.3
Mirimanoff, R.O.4
Leyvraz, S.5
Villemure, J.G.6
Stupp, R.7
-
30
-
-
0035830431
-
PCV chemotherapy for recurrent glioblastoma multiforme
-
Rappelle AC, Postma TJ, Taphoorn MJ, Groeneveld GJ, van den Bent MJ, van Groeningen CJ, Zonnenberg BA, Sneeuw KC, Heimans JJ (2001) PCV chemotherapy for recurrent glioblastoma multiforme. Neurology 56: 118-120
-
(2001)
Neurology
, vol.56
, pp. 118-120
-
-
Rappelle, A.C.1
Postma, T.J.2
Taphoorn, M.J.3
Groeneveld, G.J.4
Van Den Bent, M.J.5
Van Groeningen, C.J.6
Zonnenberg, B.A.7
Sneeuw, K.C.8
Heimans, J.J.9
-
31
-
-
5344234474
-
How effective is BCNU in recurrent glioblastoma in the modern era? A phase II trial
-
Brandes AA, Tosoni A, Amista P, Nicolardi L, Grosso D, Berti F, Ermani M (2004) How effective is BCNU in recurrent glioblastoma in the modern era? A phase II trial. Neurology 63: 1281-1284
-
(2004)
Neurology
, vol.63
, pp. 1281-1284
-
-
Brandes, A.A.1
Tosoni, A.2
Amista, P.3
Nicolardi, L.4
Grosso, D.5
Berti, F.6
Ermani, M.7
|