Effect of combined spa-exercise therapy on circulating TGF-β1 levels in patients with ankylosing spondylitis

Wiener Klinische Wochenschrift

Volumn 118, Issue 9-10, 2006, Pages 266-272

  Shehata, Medhat ^a,c,d   Schwarzmeier, Josef D ^a,b,c,d   Hilgarth, Martin ^a   Demirtas, Dita ^a   Richter, Dorothea ^a   Hubmann, Rainer ^a   Boeck, Petra ^c   Leiner, Guenther ^b,c   Falkenbach, Albrecht ^c  

^a UNIVERSITY OF VIENNA   (Austria)

^b LUDWIG BOLTZMANN INSTITUTE FOR LUNG VASCULAR RESEARCH   (Austria)

^c Badehospiz ^*  (Austria)

^d K Landsteiner Institute for Cytokine and Tumor Microenvironment   (Austria)

Author keywords

Ankylosing Spondylitis; Badgastein; Heilstollen; Radon; TGF beta

Indexed keywords

CYTOKINE; RADON; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; AGED; ANALGESIA; ANKYLOSING SPONDYLITIS; ARTICLE; CONTROLLED STUDY; EXERCISE; FEMALE; HUMAN; HYPERTHERMIC THERAPY; IMMUNOASSAY; INFLAMMATION; LOW BACK PAIN; MAJOR CLINICAL STUDY; MALE; PAIN; SPA TREATMENT; TREATMENT RESPONSE;

ADULT; AGED; BALNEOLOGY; BIOLOGICAL MARKERS; COMBINED MODALITY THERAPY; EXERCISE THERAPY; FEMALE; HUMANS; IMMUNOLOGIC FACTORS; MALE; MIDDLE AGED; RETROSPECTIVE STUDIES; SPONDYLITIS, ANKYLOSING; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TREATMENT OUTCOME;

EID: 33745745738     PISSN: 00435325     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00508-006-0560-y     Document Type: Article

References (24)

1. Kim TH, Uhm WS, Inman RD (2005) Pathogenesis of ankylosing spondylitis and reactive arthritis. Curr Opin Rheumatol 17: 400-405
2. Ellegast HH (1974) Ankylosing spondylitis - radiological manifestations (author's transi). Wien Klin Wochenschr [Suppl] 28: 5-10
3. Dagfinrud H, Kvien TK, Hagen KB (2005) The Cochrane review of physiotherapy interventions for ankylosing spondylitis. J Rheumatol 32: 1899-1906
4. Boulos P, Dougados M, Macleod SM, Hunsche E (2005) Pharmacological treatment of ankylosing spondylitis: a systematic review. Drugs 65: 2111-2127
5. Braun J, Baraliakos X, Brandt J, Sieper J (2005) Therapy of ankylosing spondylitis. Part II: biological therapies in the spondyloarthritides. Scand J Rheumatol 34: 178-190
6. Gorman JD, Sack KE, Davis JC Jr (2002) Treatment of ankylosing spondylitis by inhibition of tumor necrosis factor alpha. N Engl J Med 346: 1349-1356
7. Falkenbach A (2001) Combined radon and heat exposure for treatment of rheumatic diseases: a clinical approach. In: Kosaka M (ed) Thermotherapy for neoplasia, inflammation and pain. Springer, Berlin Heidelberg New York Tokyo, pp 495-503
8. Falkenbach A, Kovacs J, Franke A, Jorgens K, Ammer K (2005) Radon therapy for the treatment of rheumatic diseases - review and meta-analysis of controlled clinical trials. Rheumatol Int 25: 205-210
9. Falkenbach A, Jager U (2001) Is chronic lymphocytic leukemia a contraindication for radon and thermotherapy? - a case report. Wien Klin Wochenschr 113: 73-75
10. Sandri B (1974) Therapeutic results in ankylosing spondylitis in the Gasteiner Heilstollen (author's transl). Wien Klin Wochenschr [Suppl] 28: 11-12
11. van Tubergen A, Landewe R, van der HD, et al (2001) Combined spa-exercise therapy is effective in patients with ankylosing spondylitis: a randomized controlled trial. Arthritis Rheum 45: 430-438
12. Falkenbach A, Herold M (1998) In ankylosing spondylitis serum interleukin-6 correlates with the degree of mobility restriction, but not with short-term changes in the variables for mobility. Rheumatol Int 18: 103-106
13. Centrella M, Horowitz MC, Wozney JM, McCarthy TL (1994) Transforming growth factor-beta gene family members and bone. Endocr Rev 15: 27-39
14. Shehata M, Schwarzmeier JD, Hilgarth M, Hubmann R, Duechler M, Gisslinger H (2004) TGF-beta1 induces bone marrow reticulin fibrosis in hairy cell leukemia. J Clin Invest 113: 676-685
15. Annes JP, Munger JS, Rifkin DB (2003) Making sense of latent TGFbeta activation. J Cell Sci 116: 217-224
16. Braun J, Bollow M, Neure L, et al (1995) Use of immunohistologic and in situ hybridization techniques in the examination of sacroiliac joint biopsy specimens from patients with ankylosing spondylitis. Arthritis Rheum 38: 499-505
17. Krug HE (1998) Fibroblasts from mice with progressive ankylosis proliferate excessively in response to transforming growth factor-beta 1. J Investig Med 46: 134-139
18. Flanders KC, Winokur TS, Holder MG, Sporn MB (1993) Hyperthermia induces expression of transforming growth factor-beta s in rat cardiac cells in vitro and in vivo. J Clin Invest 92: 404-410
19. Weber H, Wagner AC, Jonas L, et al (2000) Heat shock response is associated with protection against acute interstitial pancreatitis in rats. Dig Dis Sci 45: 2252-2264
20. Smith JK, Dykes R, Douglas JE, Krishnaswamy G, Berk S (1999) Long-term exercise and atherogenic activity of blood mononuclear cells in persons at risk of developing ischemic heart disease. JAMA 281: 1722-1727
21. Gavin TP, Spector DA, Wagner H, Breen EC, Wagner PD (2000) Nitric oxide synthase inhibition attenuates the skeletal muscle VEGF mRNA response to exercise. J Appl Physiol 88: 1192-1198
22. Barcellos-Hoff MH, Derynck R, Tsang ML, Weatherbee JA (1994) Transforming growth factor-beta activation in irradiated murine mammary gland. J Clin Invest 93: 892-899
23. Barcellos-Hoff MH, Dix TA (1996) Redox-mediated activation of latent transforming growth factor-beta I. Mol Endocrinol 10: 1077-1083
24. Narayanan PK, Goodwin EH, Lehnert BE (1997) Alpha particles initiate biological production of superoxide anions and hydrogen peroxide in human cells. Cancer Res 57: 3963-3971