Synthesis and hypoxic-cytotoxic activity of some 3-amino-1,2,4-benzotriazine-1,4-dioxide derivatives

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 16, 2006, Pages 4209-4213

  Jiang, Faqin ^a   Yang, Bo ^a   Fan, Lingling ^a   He, Qiaojun ^a   Hu, Yongzhou ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

3 Amino 1,2,4 benzotriazine 1,4 dioxide derivatives; Cytotoxicity; Hypoxia; Synthesis

Indexed keywords

TIRAPAZAMINE;

ARTICLE; CANCER CELL CULTURE; CELL STRAIN HEPG2; CELL STRAIN K 562; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; HUMAN; HUMAN CELL; HYPOXIA; LEUKEMIA CELL LINE; LIVER CANCER; MEMBRANE POTENTIAL; MITOCHONDRIAL MEMBRANE; OXYGEN BLOOD LEVEL; PROSTATE CANCER; PROTEIN EXPRESSION;

ANOXIA; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; DRUG SCREENING ASSAYS, ANTITUMOR; HL-60 CELLS; HUMANS; INHIBITORY CONCENTRATION 50; K562 CELLS; MEMBRANE POTENTIALS; MODELS, CHEMICAL; TRIAZINES; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33745727137     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2006.05.095     Document Type: Article

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