Examining clinical trial results with single-subject analysis: An example involving behavioral and nutrition treatment for young children with cystic fibrosis

Journal of Pediatric Psychology

Volumn 31, Issue 6, 2006, Pages 574-581

  Powers, Scott W ^a,b,d   Piazza Waggoner, Carrie ^a   Jones, Julie S ^c   Ferguson, Kathleen S ^a,b   Daines, Cori ^a,b   Acton, James D ^a,b  

^a CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^b UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^c Greenville Hospital System Children's Hospital   (United States)

^d Child and Adolescent Forensic Psychiatry Service   (United States)

Author keywords

Changing criterion design; Multiple baseline design; Parenting; Pediatrics; Single case experimental designs

Indexed keywords

ANALYSIS; ARTICLE; BEHAVIOR THERAPY; CALORIC INTAKE; CHANGING CRITERION DESIGN; CHILD BEHAVIOR; CHILD PARENT RELATION; CHILD PSYCHOLOGY; CLINICAL ARTICLE; CLINICAL TRIAL; CYSTIC FIBROSIS; FEMALE; HUMAN; MALE; METHODOLOGY; MULTIPLE BASELINE DESIGN; NUTRITION; NUTRITIONAL REQUIREMENT; PARENT COUNSELING; PEDIATRICS; PRESCHOOL CHILD; SINGLE SUBJECT ANALYSIS;

BEHAVIOR THERAPY; CHILD; CHILD, PRESCHOOL; CYSTIC FIBROSIS; ENERGY INTAKE; FEMALE; HUMANS; MALE; PARENTING;

EID: 33745713004     PISSN: 01468693     EISSN: 1465735X     Source Type: Journal    
DOI: 10.1093/jpepsy/jsj049     Document Type: Article

References (25)

1. Aeschleman, S. (1991). Single-subject research designs: Some misconceptions. Rehabilitation Psychology, 36, 43-49.
2. Allen, K., Friman, P. C., & Sanger, W. (1992). Single subject design in reproductive toxicology. Reproductive Toxicology, 6, 115-121.
3. Backman, C., & Harris, S. (1999). Case studies, single-subject research, and N of 1 randomized trials: Comparisons and contrasts. American Journal of Physical Medicine and Rehabilitation, 78, 1701-1176.
4. Barlow, D. H., & Hersen, M. (1984). Single case experimental designs: Strategies for studying behavior change (2nd ed.) Boston, MA: Allyn and Bacon.
5. Borowitz, D., Baker, R., & Stallings, V. (2002). Consensus report on nutrition for pediatric patients with cystic fibrosis. Journal Pediatric Gastroenterology and Nutrition, 35, 246-259.
6. Cystic Fibrosis Foundation. (2004). Patient registry 2003: Annual data report. Bethesda, MD: Cystic Fibrosis Foundation.
7. Drotar, D., & Lemanek, K. (2001). Steps toward a clinically relevant science of interventions in pediatric settings: Introduction to the special issue. Journal of Pediatric Psychology, 26, 385-394.
8. Elder, J. (1997). Single subject experimentation for psychiatric nursing. Archives of Psychiatric Nursing, 11, 133-138.
9. ESHA. (2002). The food processor nutrition analysis and fitness software (Version 8.0). Retrieved July 7, 2005 from http://www.esha.com/products/
10. Kinugasa, T., Cerin, E., & Hooper, S. (2004). Single-subject research designs and data analyses for assessing elite athlete's conditioning. Sports Medicine, 34, 1035-1050.
11. Konstan, M., Butler, S., Wohl, M., Stoddard, M., Matousek, R., Wagener, J., et al. (2003). Growth and nutritional indexes in early life predict pulmonary function in cystic fibrosis. Journal of Pediatrics, 142, 624-630.
12. Madsen, L., & Bytzer, P. (2002). Review article: Single subject trials as a research instrument in gastrointestinal pharmacology. Alimentary Pharmacologic Therapeutics, 16, 189-196.
13. Marvel, M., & Amodei, N. (1992). Single-subject experimental designs: A practical research alternative for practicing physicians. Family Practice and Research Journal, 12, 109-121.
14. Peterson, M., Jacobs, D. J., & Milla, C. (2003). Longitudinal changes in growth parameters are correlated with changes in pulmonary function in children with cystic fibrosis. Pediatrics, 112, 588-592.
15. Powers, S. W. (2003). Nutrition in early childhood: Focus on parent interaction. Pediatric Pulmonology, S25, 138-139.
16. Powers, S. W., Byars, K. C., Mitchell, M. J., Patton, S. R., Schindler, T., & Zeller, M. H. (2003). A randomized pilot study of behavioral treatment to increase calorie intake in toddlers with cystic fibrosis. Children's Health Care, 32, 297-311.
17. Powers, S. W., Jones, J. S., Ferguson, K. S., Heidemann, M. L., Henry, R., Piazza-Waggoner, C, et al. (2004). Behavioral treatment for toddlers and preschoolers with cystic fibrosis produces recommended energy intake and normal rates of growth. Pediatric Pulmonology, S27, 361.
18. Powers, S. W., Jones, J. S., Ferguson, K. S., Piazza-Waggoner, C., Daines, C., & Acton, J. D. (in press). Randomized clinical trial of behavioral and nutrition treatment to improve energy intake and growth in toddlers and preschoolers with cystic fibrosis. Pediatrics.
19. Powers, S. W., Jones, J. S., Patton, S. R., & Janicke, D. M. (2003). Nutritional recommendations for children with cystic fibrosis. Italian Journal of Pediatrics, 29, 44-50.
20. Powers, S., Patton, S., Byars, K., Mitchell, M., Jelalian, E., Mulvihill, M., et al. (2002). Caloric intake and eating behavior in infants and toddlers with cystic fibrosis. Pediatrics, 109, 75-80.
21. Ramsey, B., Farrell, P., & Pencharz, P. (1992). Nutritional assessment and management in cystic fibrosis: A consensus report. The Consensus Committee. American Journal of Clinical Nutrition, 55, 108-116.
22. Stark, L., Jelalian, E., Mulvihill, M., Powers, S., Bowen, A., Spieth, L., et al. (1995). Eating in preschool children with cystic fibrosis and healthy peers: Behavioral analysis. Pediatrics, 95, 210-215.
23. Stark, L. J., Mackner, L. M., Patton, S. R., & Acton, J. D. (2003). Cystic fibrosis. In M. C. Roberts (Ed.), Handbook of pediatric psychology (3rd ed., pp. 286-303). New York: Guilford Press.
24. Willett, W. (1990). Nutritional epidemiology. New York: Oxford University Press.
25. Zhan, S., & Ottenbacher, K. (2001). Single subject research designs in disability research. Disability Rehabilitation, 23, 1-8.