Selective targeting of indel-inferred differences in spatial structures of homologous proteins

Journal of Bioinformatics and Computational Biology

Volumn 4, Issue 2, 2006, Pages 403-414

  Li, Yvonne Y ^a   Jones, Steven J M ^b   Cherkasov, Artem ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b CANADA'S MICHAEL SMITH GENOME SCIENCES CENTRE   (Canada)

Author keywords

Drug design; Drug targets; Indels; Protein length polymorphism; Virtual screening

Indexed keywords

ANTILEISHMANIAL AGENT; ELONGATION FACTOR 1ALPHA; NSC 107367; NSC 122281; NSC 157568; NSC 169; NSC 263851; NSC 271938; NSC 273396; NSC 279292; NSC 340235; NSC 4347; NSC 83604; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; BINDING AFFINITY; BINDING SITE; CELL SURVIVAL; COMPUTER MODEL; CONFERENCE PAPER; CONTROLLED STUDY; DRUG STRUCTURE; DRUG TARGETING; EUKARYOTE; GENE DELETION; GENE FREQUENCY; GENE INSERTION; HUMAN; LEISHMANIA DONOVANI; NONHUMAN; PARASITE VIRULENCE; PREDICTION; PROTEIN ANALYSIS; PROTEIN STRUCTURE; PROTEIN TARGETING; SCREENING TEST; SEQUENCE HOMOLOGY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMALS; BINDING SITES; COMPUTER SIMULATION; LEISHMANIA DONOVANI; MODELS, CHEMICAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; NUCLEAR PROTEINS; PEPTIDE ELONGATION FACTOR 1; PROTEIN BINDING; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS, PROTEIN; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY; TRANSCRIPTION FACTORS;

EUKARYOTA; LEISHMANIA DONOVANI;

EID: 33745712612     PISSN: 02197200     EISSN: None     Source Type: Journal    
DOI: 10.1142/S0219720006001898     Document Type: Conference Paper

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