Evolutionary conservation of motif constituents in the yeast protein interaction network

Nature Genetics

Volumn 35, Issue 2, 2003, Pages 176-179

  Wuchty, S ^a   Oltvai, Z ^b   Barabasi A L ^a  

^a UNIVERSITY OF NOTRE DAME   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; GENETIC CONSERVATION; NONHUMAN; ORTHOLOGY; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN LOCALIZATION; PROTEIN MOTIF; SACCHAROMYCES CEREVISIAE; YEAST;

ANIMALS; CONSERVED SEQUENCE; EVOLUTION, MOLECULAR; HUMANS; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION, GENETIC;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0141484611     PISSN: 10614036     EISSN: None     Source Type: Journal    
DOI: 10.1038/ng1242     Document Type: Article

References (22)

1. Hasty, J., McMillen, D. & Collins, J.J. Engineered gene circuits. Nature 420, 224-230 (2002).
2. Kitano, H. Systems biology: a brief overview. Science 295, 1662-1664 (2002).
3. Rao, C.V., Wolf, D.M. & Arkin, A.P. Control, exploitation and tolerance of intracellular noise. Nature 420, 231-237 (2002).
4. Hartwell, L.H., Hopfield, J.J., Leibler, S. & Murray, A.W. From molecular to modular cell biology. Nature 402, C47-C52 (1999).
5. Oltvai, Z.N. & Barabási, A.-L. Life's complexity pyramid. Science 298, 763-764 (2002).
6. Shen-Orr, S.S., Milo, R., Mangan, S. & Alon, U. Network motifs in the transcriptional regulation network of Escherichia coli. Nat. Genet. 31, 64-68 (2002).
7. Milo, R., Shen-Orr, S.S., Itzkovitz, S., Kashtan, N. & Alon, U. Network motifs: simple building blocks of complex networks. Science 298, 824-827 (2002).
8. Lee, T.I. et al. Transcriptional regulatory networks in Saccharomyces cerevisiae. Science 298, 799-804 (2002).
9. Xenarios, I. et al. DIP, the Database of Interacting Proteins: a research tool for studying cellular networks of protein interactions. Nucleic Acids Res. 30, 303-305 (2002).
10. Von Mering, C. et al. Comparative assessment of large-scale data sets of protein interactions. Nature 417, 399-403 (2002).
11. Remm, M., Storm, C.E.V. & Sonnhammer, E.L. Automatic clustering of orthologs and inparalogs from pairwise species comparisons. J. Mol. Biol. 314, 1041-1052 (2001).
12. Watts, D.J. & Strogatz, S.H. Collective dynamics of 'small-world' networks. Nature 393, 440-442 (1998).
13. Ravasz, E., Somera, A.L., Mongru, D.A., Oltvai, Z.N. & Barabási, A.-L. Hierarchical organization of modularity in metabolic networks. Science 297, 1551-1555 (2002).
14. Rives, A.W. & Galitski, T. Modular organization of cellular networks. Proc. Natl. Acad. Sci. USA 100, 1128-1133 (2003).
15. Mewes, H.W. et al. MIPS: a database for genomes and protein sequences. Nucleic Acids Res. 30, 31-34 (2002).
16. Hurst, L.D. & Smith, N.G. Do essential genes evolve slowly? Curr. Biol. 9, 747-750 (1999).
17. Hirsh, A.E. & Fraser, H.B. Protein dispensability and rate of evolution. Nature 411 1046-1049 (2001).
18. Hirsh, A.E. & Fraser, H.B. Genomic function (communication arising): rate of evolution and gene dispensability. Nature 421, 497-498 (2003).
19. Fraser, H.B., Hirsh, A.E., Steinmetz, L.M., Scharfe, C. & Feldman, M.W. Evolutionary rate in the protein interaction network. Science 296, 750-752 (2000).
20. Pal, C., Papp, B. & Hurst, L.D. Genomic function (communication arising): rate of evolution and gene dispensability. Nature 421, 496-497 (2003).
21. Jordan, I.K., Rogozin, I.B., Wolf, Y.I. & Koonin, E.V. Essential genes are more evolutionarily conserved than are nonessential genes in bacteria. Genome Res. 12, 962-968 (2002).
22. Snel, B., Bork, P. & Huynen, M.A. The identification of functional modules from the genomic association of genes. Proc. Natl. Acad. Sci. USA 99, 5890-5895 (2002).