Exposure of eyes to perfume: A double-blind, placebo-controlled experiment

Indoor Air

Volumn 16, Issue 4, 2006, Pages 276-281

  Elberling, J ^a,c   Duus Johansen, J ^a   Dirksen, A ^a   Mosbech, H ^b  

^a GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^b Rigshospitalet   (Denmark)

^c National Allergy Research Centre   (Denmark)

Author keywords

Challenge; Eczema; Eye irritation; Fragrance; Multiple chemical sensitivity; Respiratory

Indexed keywords

CHALLENGE; CHEMICAL SENSITIVITY; CONTROLLED EXPERIMENT; ECZEMA; EXPOSURE LEVEL; EYE IRRITATION; HEALTHY VOLUNTEERS; MULTIPLE CHEMICAL SENSITIVITY; RESPIRATORY; RESPIRATORY SYMPTOMS;

EID: 33745712428     PISSN: 09056947     EISSN: 16000668     Source Type: Journal    
DOI: 10.1111/j.1600-0668.2006.00424.x     Document Type: Article

References (21)

1. Bauer, K., Garbe, D. and Surburg, H. (1990) Common Fragrance and Flavor Materials, New York, NY, VCH Verlagsgesellschaft, Weinheim VCH Publishers.
2. Baur, X., Schneider, E.M., Wieners, D. and Czuppon, A.B. (1999) Occupational asthma to perfume, Allergy, 54, 1334-1335.
3. Bryant, B., and Silver, W.L. (2000) Chemestesis: the common chemical sense. In: Finger, T.E. Silver, W.L. and Restrepo, D. (eds) The Neurobiology of Taste and Smell, 2nd edn, New York, Wiley-Liss, Inc., 73-100.
4. Cometto-Muniz, J.E. and Cain, W.S. (1995) Relative sensitivity of the ocular trigeminal, nasal trigeminal and olfactory systems to airborne chemicals, Chem. Senses, 20, 191-198.
5. Cometto-Muniz, J.E., Cain, W.S. and Abraham, M.H. (2004) Detection of single and mixed VOCs by smell and by sensory irritation. Indoor Air, 14 (Suppl. 8), 108-117.
6. Dalton, P. (2003) Upper airway irritation, odor perception and health risk due to airborne chemicals, Toxicol. Lett., 140, 239-248;
7. Dalton, P. Toxicol. Lett., 141, 239-248.
8. Doty, R.L., Cometto-Muniz, J.E., Jalowayski, A.A., Dalton, P., Kendal-Reed, M. and Hodgson, M. (2004) Assessment of upper respiratory tract and ocular irritative effects of volatile chemicals in humans, Crit. Rev. Toxicol., 34, 85-142.
9. Elberling, J., Linneberg, A., Mosbech, H., Dirksen, A., Frolund, L., Madsen, F., Nielsen, N.H. and Johansen, J.D. (2004) A link between skin and airways regarding sensitivity to fragrance products?, Br. J. Dermatol., 151, 1197-1203.
10. Elberling, J., Linneberg, A., Dirksen, A., Johansen, J.D., Frolund, L., Madsen, F., Nielsen, N.H. and Mosbech, H. (2005) Mucosal symptoms elicited by fragrance products in a population-based sample in relation to atopy and bronchial hyperreactivity, Clin. Exp. Allergy, 35, 75-81.
11. Frosch, P., Johansen, J.D. and White, I.R. (1998) Fragrances; Beneficial and Adverse Effects, Berlin, Heidelberg, Germany, Springer-Verlag.
12. Jensen, O.C. and Petersen, I. (1991) Occupational asthma caused by scented gravel in cat litter boxes, ugeskr. laeger, 153, 939-940.
13. Johansen, J.D., Rastogi, S.C. and Menne, T. (1996) Contact allergy to popular perfumes; assessed by patch test, use test and chemical analysis, Br. J. Dermatol., 135, 419-422.
14. Johansen, J.D., Frosch, P.J., Rastogi, S.C. and Menne, T. (2001) Testing with fine fragrances in eczema patients: results and test methods, Contact Derm., 44, 304-307.
15. Kumar, P., Caradonna-Graham, V.M., Gupta, S., Cai, X., Rao, P.N. and Thompson, J. (1995) Inhalation challenge effects of perfume scent strips in patients with asthma, Ann. Allergy Asthma Immunol., 75, 429-433.
16. Millqvist, E. and Lowhagen, O. (1996) Placebo-controlled challenges with perfume in patients with asthma-like symptoms, Allergy, 51, 434-439.
17. Millqvist, E., Bengtsson, U. and Lowhagen, O. (1999) Provocations with perfume in the eyes induce airway symptoms in patients with sensory hyperreactivity, Allergy, 54, 495-499.
18. Nojgaard, J.K., Christensen, K.B. and Wolkoff, P. (2005) The effect on human eye blink frequency of exposure to limonene oxidation products and methacrolein, Toxicol. Lett., 156, 241-251.
19. Opiekun, R.E., Smeets, M., Sulewski, M., Rogers, R., Prasad, N., Vedula, U. and Dalton, P. (2003) Assessment of ocular and nasal irritation in asthmatics resulting from fragrance exposure, Clin. Exp. Allergy, 33, 1256-1265.
20. Shusterman, D. (2001) Odor-associated health complaints: competing explanatory models, Chem. Senses, 26, 339-343.
21. Wilkinson, D.S., Fregert, S., Magnusson, B., Bandmann, H.J., Calnan, C.D., Cronin, E., Hjorth, N., Maibach, H.J., Malalten, K.E., Meneghini, C.L. and Pirila, V. (1970) Terminology of contact dermatitis, Acta Derm. Venereol., 50, 287-292.