메뉴 건너뛰기




Volumn 32, Issue 4, 2006, Pages 352-361

Effects of anagrelide on megakaryopoiesis and platelet production

Author keywords

Anagrelide; Apoptosis; Endoreduplicative capacity; Fibrogenic activity; Hydroxyurea; Maturation defects; Megakaryocytes; Proliferation

Indexed keywords

ANAGRELIDE; CD61 ANTIGEN; CYCLINE; HYDROXYUREA;

EID: 33745700695     PISSN: 00946176     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2006-942756     Document Type: Article
Times cited : (18)

References (81)
  • 1
    • 1542615163 scopus 로고    scopus 로고
    • Thrombocytosis
    • Schafer AI. Thrombocytosis. N Engl J Med 2004;350:1211-1219
    • (2004) N Engl J Med , vol.350 , pp. 1211-1219
    • Schafer, A.I.1
  • 2
    • 0034778313 scopus 로고    scopus 로고
    • Current opinion in essential thrombocythemia: Pathogenesis, diagnosis, and management
    • Tefferi A, Murphy S. Current opinion in essential thrombocythemia: pathogenesis, diagnosis, and management. Blood Rev 2001;15:121-131
    • (2001) Blood Rev , vol.15 , pp. 121-131
    • Tefferi, A.1    Murphy, S.2
  • 3
    • 0030727717 scopus 로고    scopus 로고
    • Risk factors and prevention of vascular complications in polycythemia vera
    • Barbui T, Finazzi G. Risk factors and prevention of vascular complications in polycythemia vera. Semin Thromb Hemost 1997;23:455-461
    • (1997) Semin Thromb Hemost , vol.23 , pp. 455-461
    • Barbui, T.1    Finazzi, G.2
  • 4
    • 0037251066 scopus 로고    scopus 로고
    • Indications for lowering platelet numbers in essential thrombocythemia
    • Barbui T. Indications for lowering platelet numbers in essential thrombocythemia. Semin Hematol 2003;40:22-25
    • (2003) Semin Hematol , vol.40 , pp. 22-25
    • Barbui, T.1
  • 5
    • 0141887079 scopus 로고    scopus 로고
    • Treatment indications and choice of a platelet-lowering agent in essential thrombocythemia
    • Barbui T, Finazzi G. Treatment indications and choice of a platelet-lowering agent in essential thrombocythemia. Curr Hematol Rep 2003;2:248-256
    • (2003) Curr Hematol Rep , vol.2 , pp. 248-256
    • Barbui, T.1    Finazzi, G.2
  • 6
    • 0141740256 scopus 로고    scopus 로고
    • Pharmacotherapy of essential thrombocythaemia: Economic considerations
    • Griesshammer M, Langer C. Pharmacotherapy of essential thrombocythaemia: economic considerations. Expert Opin Pharmacother 2003;4:1499-1505
    • (2003) Expert Opin Pharmacother , vol.4 , pp. 1499-1505
    • Griesshammer, M.1    Langer, C.2
  • 7
    • 0034157369 scopus 로고    scopus 로고
    • Anagrelide: A novel agent for the treatment of myeloproliferative disorders
    • Pescatore SL, Lindley C. Anagrelide: a novel agent for the treatment of myeloproliferative disorders. Expert Opin Pharmacother 2000;1:537-546
    • (2000) Expert Opin Pharmacother , vol.1 , pp. 537-546
    • Pescatore, S.L.1    Lindley, C.2
  • 8
    • 0030803837 scopus 로고    scopus 로고
    • Anagrelide as a new platelet-lowering agent in essential thrombocythemia: Mechanism of actin, efficacy, toxicity, current indications
    • Tefferi A, Silverstein MN, Petitt RM, Mesa RA, Solberg LA Jr. Anagrelide as a new platelet-lowering agent in essential thrombocythemia: mechanism of actin, efficacy, toxicity, current indications. Semin Thromb Hemost 1997;23:379-383
    • (1997) Semin Thromb Hemost , vol.23 , pp. 379-383
    • Tefferi, A.1    Silverstein, M.N.2    Petitt, R.M.3    Mesa, R.A.4    Solberg Jr., L.A.5
  • 11
    • 0026576978 scopus 로고
    • Effect of anagrelide on platelet count and function in patients with thrombocytosis and myeloproliferative disorders
    • Balduini CL, Bertolino G, Noris P, Ascari E. Effect of anagrelide on platelet count and function in patients with thrombocytosis and myeloproliferative disorders. Haematologica 1992;77:40-43
    • (1992) Haematologica , vol.77 , pp. 40-43
    • Balduini, C.L.1    Bertolino, G.2    Noris, P.3    Ascari, E.4
  • 12
    • 0026785698 scopus 로고
    • Therapy with anagrelide in patients affected by essential thrombocythemia: Preliminary results
    • Mazzucconi MG, De Sanctis V, Chistolini A, Dragoni F, Mandelli F. Therapy with anagrelide in patients affected by essential thrombocythemia: preliminary results. Haematologica 1992;77:315-317
    • (1992) Haematologica , vol.77 , pp. 315-317
    • Mazzucconi, M.G.1    De Sanctis, V.2    Chistolini, A.3    Dragoni, F.4    Mandelli, F.5
  • 13
    • 0031830861 scopus 로고    scopus 로고
    • Anagrelide, a novel platelet lowering option in essential thrombocythaemia: Treatment experience in 48 patients in Germany
    • Petrides PE, Beykirch MK, Trapp OM. Anagrelide, a novel platelet lowering option in essential thrombocythaemia: treatment experience in 48 patients in Germany. Eur J Haematol 1998;61:71-76
    • (1998) Eur J Haematol , vol.61 , pp. 71-76
    • Petrides, P.E.1    Beykirch, M.K.2    Trapp, O.M.3
  • 14
    • 0033003618 scopus 로고    scopus 로고
    • Studies of platelet volume, chemistry and function in patients with essential thrombocythaemia treated with anagrelide
    • Bellucci S, Legrand C, Boval B, Drouet L, Caen J. Studies of platelet volume, chemistry and function in patients with essential thrombocythaemia treated with anagrelide. Br J Haematol 1999;104:886-892
    • (1999) Br J Haematol , vol.104 , pp. 886-892
    • Bellucci, S.1    Legrand, C.2    Boval, B.3    Drouet, L.4    Caen, J.5
  • 15
    • 0032926216 scopus 로고    scopus 로고
    • Treatment of essential thrombocythemia with anagrelide
    • Silverstein MN, Tefferi A. Treatment of essential thrombocythemia with anagrelide. Semin Hematol 1999;36:23-25
    • (1999) Semin Hematol , vol.36 , pp. 23-25
    • Silverstein, M.N.1    Tefferi, A.2
  • 17
    • 0037483282 scopus 로고
    • Anagrelide, a therapy for thrombocythemic states: Experience in 577 patients
    • Anagrelide Study Group. Anagrelide, a therapy for thrombocythemic states: experience in 577 patients. Am J Med 1992;92:69-76
    • (1992) Am J Med , vol.92 , pp. 69-76
  • 18
    • 0031047572 scopus 로고    scopus 로고
    • Anagrelide for control of thrombocythemia in polycythemia and other myeloproliferative disorders
    • Petitt RM, Silverstein MN, Petrone ME. Anagrelide for control of thrombocythemia in polycythemia and other myeloproliferative disorders. Semin Hematol 1997;34:51-54
    • (1997) Semin Hematol , vol.34 , pp. 51-54
    • Petitt, R.M.1    Silverstein, M.N.2    Petrone, M.E.3
  • 19
    • 0036398450 scopus 로고    scopus 로고
    • Essential thrombocythemia: Diagnosis and treatment, with special emphasis on the use of anagrelide
    • Andersson BS. Essential thrombocythemia: diagnosis and treatment, with special emphasis on the use of anagrelide. Hematology (Am Soc Hematol Educ Program) 2002;7:173-177
    • (2002) Hematology (Am Soc Hematol Educ Program) , vol.7 , pp. 173-177
    • Andersson, B.S.1
  • 20
    • 0036303540 scopus 로고    scopus 로고
    • Therapeutic options for essential thrombocythemia and polycythemia vera
    • Solberg LA Jr. Therapeutic options for essential thrombocythemia and polycythemia vera. Semin Oncol 2002;29:10-15
    • (2002) Semin Oncol , vol.29 , pp. 10-15
    • Solberg Jr., L.A.1
  • 21
    • 0035865604 scopus 로고    scopus 로고
    • Long-term use of anagrelide in young patients with essential thrombocythemia
    • Storen EC, Tefferi A. Long-term use of anagrelide in young patients with essential thrombocythemia. Blood 2001;97:863-866
    • (2001) Blood , vol.97 , pp. 863-866
    • Storen, E.C.1    Tefferi, A.2
  • 22
    • 0345363281 scopus 로고    scopus 로고
    • Role of anagrelide in the treatment of thrombocytosis
    • Brooks WG, Stanley DD, Goode JV. Role of anagrelide in the treatment of thrombocytosis. Ann Pharmacother 1999;33: 1116-1118, 1121
    • (1999) Ann Pharmacother , vol.33 , pp. 1116-1118
    • Brooks, W.G.1    Stanley, D.D.2    Goode, J.V.3
  • 23
    • 4344605780 scopus 로고    scopus 로고
    • Anagrelide: A decade of clinical experience with its use for the treatment of primary thrombocythaemia
    • Petrides PE. Anagrelide: a decade of clinical experience with its use for the treatment of primary thrombocythaemia. Expert Opin Pharmacother 2004;5:1781-1798
    • (2004) Expert Opin Pharmacother , vol.5 , pp. 1781-1798
    • Petrides, P.E.1
  • 24
    • 20144379068 scopus 로고    scopus 로고
    • A critical review of anagrelide therapy in essential thrombocythemia and related disorders
    • Dingli D, Tefferi A. A critical review of anagrelide therapy in essential thrombocythemia and related disorders. Leuk Lymphoma 2005;46:641-650
    • (2005) Leuk Lymphoma , vol.46 , pp. 641-650
    • Dingli, D.1    Tefferi, A.2
  • 25
    • 0030995141 scopus 로고    scopus 로고
    • Is treatment with hydroxyurea leukemogenic in patients with essential thrombocythemia? An analysis of three new cases of leukaemic transformation and review of the literature
    • Liozon E, Brigaudeau C, Trimoreau F, et al. Is treatment with hydroxyurea leukemogenic in patients with essential thrombocythemia? An analysis of three new cases of leukaemic transformation and review of the literature. Hematol Cell Ther 1997;39:11-18
    • (1997) Hematol Cell Ther , vol.39 , pp. 11-18
    • Liozon, E.1    Brigaudeau, C.2    Trimoreau, F.3
  • 26
    • 0031982894 scopus 로고    scopus 로고
    • Acute myeloid leukemia and myelodysplastic syndromes following essential thrombocythemia treated with hydroxyurea: High proportion of cases with 17p deletion
    • Sterkers Y, Preudhomme C, Lai JL, et al. Acute myeloid leukemia and myelodysplastic syndromes following essential thrombocythemia treated with hydroxyurea: high proportion of cases with 17p deletion. Blood 1998;91:616-622
    • (1998) Blood , vol.91 , pp. 616-622
    • Sterkers, Y.1    Preudhomme, C.2    Lai, J.L.3
  • 27
    • 0032872239 scopus 로고    scopus 로고
    • Treatment of essential thrombocythemia with special emphasis on leukemogenic risk
    • Finazzi G, Barbui T. Treatment of essential thrombocythemia with special emphasis on leukemogenic risk. Ann Hematol 1999;78:389-392
    • (1999) Ann Hematol , vol.78 , pp. 389-392
    • Finazzi, G.1    Barbui, T.2
  • 28
    • 0034025273 scopus 로고    scopus 로고
    • Leukemia and myelodysplasia effect of multiple cytotoxic therapy in essential thrombocythemia
    • Randi ML, Fabris F, Girolami A. Leukemia and myelodysplasia effect of multiple cytotoxic therapy in essential thrombocythemia. Leuk Lymphoma 2000;37:379-385
    • (2000) Leuk Lymphoma , vol.37 , pp. 379-385
    • Randi, M.L.1    Fabris, F.2    Girolami, A.3
  • 29
    • 2442677684 scopus 로고    scopus 로고
    • The leukemia controversy in myeloproliferative disorders: Is it a natural progression of disease, a secondary sequela of therapy, or a combination of both?
    • Barbui T. The leukemia controversy in myeloproliferative disorders: is it a natural progression of disease, a secondary sequela of therapy, or a combination of both? Semin Hematol 2004;41:15-17
    • (2004) Semin Hematol , vol.41 , pp. 15-17
    • Barbui, T.1
  • 30
    • 0033781129 scopus 로고    scopus 로고
    • Second malignancies in patients with essential thrombocythaemia treated with busulphan and hydroxyurea: Long-term follow-up of a randomized clinical trial
    • Finazzi G, Ruggeri M, Rodeghiero F, Barbui T. Second malignancies in patients with essential thrombocythaemia treated with busulphan and hydroxyurea: long-term follow-up of a randomized clinical trial. Br J Haematol 2000;110:577-583
    • (2000) Br J Haematol , vol.110 , pp. 577-583
    • Finazzi, G.1    Ruggeri, M.2    Rodeghiero, F.3    Barbui, T.4
  • 31
    • 2442690281 scopus 로고    scopus 로고
    • Treatment paradigms in the management of myeloproliferative disorders
    • Fruchtman SM. Treatment paradigms in the management of myeloproliferative disorders. Semin Hematol 2004;41:18-22
    • (2004) Semin Hematol , vol.41 , pp. 18-22
    • Fruchtman, S.M.1
  • 32
    • 0030064767 scopus 로고    scopus 로고
    • Acute myeloid leukemia evolving from essential thrombocythemia in two patients treated with hydroxyurea
    • Furgerson JL, Vukelja SJ, Baker WJ, O'Rourke TJ. Acute myeloid leukemia evolving from essential thrombocythemia in two patients treated with hydroxyurea. Am J Hematol 1996; 51:137-140
    • (1996) Am J Hematol , vol.51 , pp. 137-140
    • Furgerson, J.L.1    Vukelja, S.J.2    Baker, W.J.3    O'Rourke, T.J.4
  • 33
    • 0028795275 scopus 로고
    • Leukemic transformation of polycythemia vera and essential thrombocythemia possibly associated with an alkylating agent
    • Higuchi T, Okada S, Mori H, Niikura H, Omine M, Terada H. Leukemic transformation of polycythemia vera and essential thrombocythemia possibly associated with an alkylating agent. Cancer 1995;75:471-477
    • (1995) Cancer , vol.75 , pp. 471-477
    • Higuchi, T.1    Okada, S.2    Mori, H.3    Niikura, H.4    Omine, M.5    Terada, H.6
  • 34
    • 0025009008 scopus 로고
    • Cytogenetic abnormalities and leukemic transformation in hydroxyurea-treated patients with Philadelphia chromosome negative chronic myeloproliferative disease
    • Löfvenberg E, Nordenson I, Wahlin A. Cytogenetic abnormalities and leukemic transformation in hydroxyurea-treated patients with Philadelphia chromosome negative chronic myeloproliferative disease. Cancer Genet Cytogenet 1990;49: 57-67
    • (1990) Cancer Genet Cytogenet , vol.49 , pp. 57-67
    • Löfvenberg, E.1    Nordenson, I.2    Wahlin, A.3
  • 35
    • 0042925574 scopus 로고    scopus 로고
    • Acute leukemia and myelodysplasia in patients with a Philadelphia chromosome negative chronic myeloproliferative disorder treated with hydroxyurea alone or with hydroxyurea after busulphan
    • Nielsen I, Hasselbalch HC. Acute leukemia and myelodysplasia in patients with a Philadelphia chromosome negative chronic myeloproliferative disorder treated with hydroxyurea alone or with hydroxyurea after busulphan. Am J Hematol 2003;74:26-31
    • (2003) Am J Hematol , vol.74 , pp. 26-31
    • Nielsen, I.1    Hasselbalch, H.C.2
  • 36
    • 0028276190 scopus 로고
    • Acute leukaemia after hydroxyurea therapy in polycythaemia vera and allied disorders: Prospective study of efficacy and leukaemogenicity with therapeutic implications
    • Weinfeld A, Swolin B, Westin J. Acute leukaemia after hydroxyurea therapy in polycythaemia vera and allied disorders: prospective study of efficacy and leukaemogenicity with therapeutic implications. Eur J Haematol 1994;52:134-139
    • (1994) Eur J Haematol , vol.52 , pp. 134-139
    • Weinfeld, A.1    Swolin, B.2    Westin, J.3
  • 37
    • 0021709130 scopus 로고
    • Inhibition of platelet production induced by an antiplatelet drug, anagrelide, in normal volunteers
    • Abe Andes W, Noveck RJ, Fleming JS. Inhibition of platelet production induced by an antiplatelet drug, anagrelide, in normal volunteers. Thromb Haemost 1984;52:325-328
    • (1984) Thromb Haemost , vol.52 , pp. 325-328
    • Abe Andes, W.1    Noveck, R.J.2    Fleming, J.S.3
  • 38
    • 0026639799 scopus 로고
    • Analysis of the mechanism of anagrelide-induced thrombocytopenia in humans
    • Mazur EM, Rosmarin AG, Sohl PA, Newton JL, Narendran A. Analysis of the mechanism of anagrelide-induced thrombocytopenia in humans. Blood 1992;79:1931-1937
    • (1992) Blood , vol.79 , pp. 1931-1937
    • Mazur, E.M.1    Rosmarin, A.G.2    Sohl, P.A.3    Newton, J.L.4    Narendran, A.5
  • 39
    • 9844256082 scopus 로고    scopus 로고
    • The effects of anagrelide on human megakaryocytopoiesis
    • Solberg LA Jr, Tefferi A, Oles KJ, et al. The effects of anagrelide on human megakaryocytopoiesis. Br J Haematol 1997;99:174-180
    • (1997) Br J Haematol , vol.99 , pp. 174-180
    • Solberg Jr., L.A.1    Tefferi, A.2    Oles, K.J.3
  • 40
    • 0032701822 scopus 로고    scopus 로고
    • Dual implication of fibrogenic cytokines in the pathogenesis of fibrosis and myeloproliferation in myeloid metaplasia with myelofibrosis
    • Le Bousse-Kerdiles MC, Martyre MC. Dual implication of fibrogenic cytokines in the pathogenesis of fibrosis and myeloproliferation in myeloid metaplasia with myelofibrosis. Ann Hematol 1999;78:437-444
    • (1999) Ann Hematol , vol.78 , pp. 437-444
    • Le Bousse-Kerdiles, M.C.1    Martyre, M.C.2
  • 41
    • 0141956031 scopus 로고    scopus 로고
    • Critical review of pathogenetic mechanisms in myelofibrosis with myeloid metaplasia
    • Martyre MC. Critical review of pathogenetic mechanisms in myelofibrosis with myeloid metaplasia. Curr Hematol Rep 2003;2:257-263
    • (2003) Curr Hematol Rep , vol.2 , pp. 257-263
    • Martyre, M.C.1
  • 42
    • 0036232556 scopus 로고    scopus 로고
    • Polymorphonuclear neutrophil and megakaryocyte mutual involvement in myelofibrosis pathogenesis
    • Schmitt A, Drouin A, Masse JM, Guichard J, Shagraoui H, Cramer EM. Polymorphonuclear neutrophil and megakaryocyte mutual involvement in myelofibrosis pathogenesis. Leuk Lymphoma 2002;43:719-724
    • (2002) Leuk Lymphoma , vol.43 , pp. 719-724
    • Schmitt, A.1    Drouin, A.2    Masse, J.M.3    Guichard, J.4    Shagraoui, H.5    Cramer, E.M.6
  • 43
    • 21444434751 scopus 로고    scopus 로고
    • Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia
    • Harrison CN, Campbell PJ, Buck G, et al. Hydroxyurea compared with anagrelide in high-risk essential thrombocythemia. N Engl J Med 2005;353:33-45
    • (2005) N Engl J Med , vol.353 , pp. 33-45
    • Harrison, C.N.1    Campbell, P.J.2    Buck, G.3
  • 44
    • 0032854508 scopus 로고    scopus 로고
    • Bone marrow effects of anagrelide therapy in patients with myelofibrosis with myeloid metaplasia
    • Yoon SY, Li CY, Mesa RA, Tefferi A. Bone marrow effects of anagrelide therapy in patients with myelofibrosis with myeloid metaplasia. Br J Haematol 1999;106:682-688
    • (1999) Br J Haematol , vol.106 , pp. 682-688
    • Yoon, S.Y.1    Li, C.Y.2    Mesa, R.A.3    Tefferi, A.4
  • 45
    • 0036493584 scopus 로고    scopus 로고
    • Effects of anagrelide on in vivo megakaryocyte proliferation and maturation in essential thrombocythemia
    • Tomer A. Effects of anagrelide on in vivo megakaryocyte proliferation and maturation in essential thrombocythemia. Blood 2002;99:1602-1609
    • (2002) Blood , vol.99 , pp. 1602-1609
    • Tomer, A.1
  • 46
    • 0024337532 scopus 로고
    • Flow cytometric analysis of megakaryocytes from patients with abnormal platelet counts
    • Tomer A, Friese P, Conklin R, et al. Flow cytometric analysis of megakaryocytes from patients with abnormal platelet counts. Blood 1989;74:594-601
    • (1989) Blood , vol.74 , pp. 594-601
    • Tomer, A.1    Friese, P.2    Conklin, R.3
  • 47
    • 0023766146 scopus 로고
    • The immunohistological detection of platelets, megakaryocytes and thrombi in routinely processed specimens
    • Gatter KC, Cordell JL, Turley H, et al. The immunohistological detection of platelets, megakaryocytes and thrombi in routinely processed specimens. Histopathology 1988;13:257-267
    • (1988) Histopathology , vol.13 , pp. 257-267
    • Gatter, K.C.1    Cordell, J.L.2    Turley, H.3
  • 48
    • 0025111663 scopus 로고
    • Megakaryocyte precursors (promegakaryoblasts and megakaryoblasts) in the normal human bone marrow. An immunohistochemical and morphometric study on routinely processed trephine biopsies
    • Thiele J, Wagner S, Dienemann D, Wienhold S, Fischer R, Stein H. Megakaryocyte precursors (promegakaryoblasts and megakaryoblasts) in the normal human bone marrow. An immunohistochemical and morphometric study on routinely processed trephine biopsies. Anal Quant Cytol Histol 1990;12:285-289
    • (1990) Anal Quant Cytol Histol , vol.12 , pp. 285-289
    • Thiele, J.1    Wagner, S.2    Dienemann, D.3    Wienhold, S.4    Fischer, R.5    Stein, H.6
  • 49
    • 0025220116 scopus 로고
    • Megakaryocyte precursors (pro- and megakaryoblasts) in bone marrow tissue from patients with reactive thrombocytosis, polycythemia vera and primary (essential) thrombocythemia. An immunomorphometric study
    • Thiele J, Wagner S, Degel C, et al. Megakaryocyte precursors (pro- and megakaryoblasts) in bone marrow tissue from patients with reactive thrombocytosis, polycythemia vera and primary (essential) thrombocythemia. An immunomorphometric study. Virchows Arch B Cell Pathol Incl Mol Pathol 1990;58:295-302
    • (1990) Virchows Arch B Cell Pathol Incl Mol Pathol , vol.58 , pp. 295-302
    • Thiele, J.1    Wagner, S.2    Degel, C.3
  • 50
    • 0022446550 scopus 로고
    • Separation of human megakaryocytes by state of differentiation on continuous gradients of Percoll: Size and ploidy analysis of cells identified by monoclonal antibody to glycoprotein IIb/IIIa
    • Ishibashi T, Ruggeri ZM, Harker LA, Burstein SA. Separation of human megakaryocytes by state of differentiation on continuous gradients of Percoll: size and ploidy analysis of cells identified by monoclonal antibody to glycoprotein IIb/IIIa. Blood 1986;67:1286-1292
    • (1986) Blood , vol.67 , pp. 1286-1292
    • Ishibashi, T.1    Ruggeri, Z.M.2    Harker, L.A.3    Burstein, S.A.4
  • 51
    • 0023095070 scopus 로고
    • Human megakaryocytes. IV. Growth and characterization of clonable megakaryocyte progenitors in agar
    • Levene RB, Williams NT, Lamaziere JM, Rabellino EM. Human megakaryocytes. IV. Growth and characterization of clonable megakaryocyte progenitors in agar. Exp Hematol 1987;15:181-189
    • (1987) Exp Hematol , vol.15 , pp. 181-189
    • Levene, R.B.1    Williams, N.T.2    Lamaziere, J.M.3    Rabellino, E.M.4
  • 52
    • 0020469589 scopus 로고
    • The significance of megakaryocyte size
    • Levine RF, Hazzard KC, Lamberg JD. The significance of megakaryocyte size. Blood 1982;60:1122-1131
    • (1982) Blood , vol.60 , pp. 1122-1131
    • Levine, R.F.1    Hazzard, K.C.2    Lamberg, J.D.3
  • 53
    • 0020319589 scopus 로고
    • The origin, development and regulation of megakaryocytes
    • Williams N, Levine RF. The origin, development and regulation of megakaryocytes. Br J Haematol 1982;52:173-180
    • (1982) Br J Haematol , vol.52 , pp. 173-180
    • Williams, N.1    Levine, R.F.2
  • 54
    • 0015056399 scopus 로고
    • Polyploidization of megakaryocytes in normal humans, in patients with idiopathic thrombocytopenia and with pernicious anaemia
    • Queisser U, Queisser W, Spiertz B. Polyploidization of megakaryocytes in normal humans, in patients with idiopathic thrombocytopenia and with pernicious anaemia. Br J Haematol 1971;20:489-501
    • (1971) Br J Haematol , vol.20 , pp. 489-501
    • Queisser, U.1    Queisser, W.2    Spiertz, B.3
  • 55
    • 0242299236 scopus 로고    scopus 로고
    • Anagrelide-induced bone marrow changes during therapy of chronic myeloproliferative disorders with thrombocytosis. An immunohistochemical and morphometric study of sequential trephine biopsies
    • Thiele J, Kvasnicka HM, Fuchs N, Brunnbauer K, Volkwein N, Schmitt-Graeff A. Anagrelide-induced bone marrow changes during therapy of chronic myeloproliferative disorders with thrombocytosis. An immunohistochemical and morphometric study of sequential trephine biopsies. Haematologica 2003;88:1130-1138
    • (2003) Haematologica , vol.88 , pp. 1130-1138
    • Thiele, J.1    Kvasnicka, H.M.2    Fuchs, N.3    Brunnbauer, K.4    Volkwein, N.5    Schmitt-Graeff, A.6
  • 56
    • 0025219285 scopus 로고
    • Review: Assessment of cell proliferation in histological material
    • Hall PA, Levison DA. Review: assessment of cell proliferation in histological material. J Clin Pathol 1990;43:184-192
    • (1990) J Clin Pathol , vol.43 , pp. 184-192
    • Hall, P.A.1    Levison, D.A.2
  • 57
    • 27144556120 scopus 로고    scopus 로고
    • Anagrelide does not exert a myelodysplastic effect on megakaryopoiesis - A comparative immunohistochemical and morphometric study with hydroxyurea
    • Thiele J, Kvasnicka HM, Ollig S, Schmitt-Graeff A. Anagrelide does not exert a myelodysplastic effect on megakaryopoiesis-a comparative immunohistochemical and morphometric study with hydroxyurea. Histol Histopathol 2005;20:1071-1076
    • (2005) Histol Histopathol , vol.20 , pp. 1071-1076
    • Thiele, J.1    Kvasnicka, H.M.2    Ollig, S.3    Schmitt-Graeff, A.4
  • 58
    • 0021234143 scopus 로고
    • Bone marrow histology in myelodysplastic syndromes. I. Histological findings in myelodysplastic syndromes and comparison with bone marrow smears
    • Tricot G, De Wolf-Peeters C, Hendrickx B, Verwilghen RL. Bone marrow histology in myelodysplastic syndromes. I. Histological findings in myelodysplastic syndromes and comparison with bone marrow smears. Br J Haematol 1984;57:423-430
    • (1984) Br J Haematol , vol.57 , pp. 423-430
    • Tricot, G.1    De Wolf-Peeters, C.2    Hendrickx, B.3    Verwilghen, R.L.4
  • 59
    • 0023096812 scopus 로고
    • Histopathology of myelodysplastic syndromes. The FAB classification (proposals) applied to bone marrow biopsy
    • Delacretaz F, Schmidt PM, Piguet D, Bachmann F, Costa J. Histopathology of myelodysplastic syndromes. The FAB classification (proposals) applied to bone marrow biopsy. Am J Clin Pathol 1987;87:180-186
    • (1987) Am J Clin Pathol , vol.87 , pp. 180-186
    • Delacretaz, F.1    Schmidt, P.M.2    Piguet, D.3    Bachmann, F.4    Costa, J.5
  • 60
    • 0025345315 scopus 로고
    • Megakaryocytes in myelodysplasia: An immunohistochemical study on bone marrow trephines
    • Fox SB, Lorenzen J, Heryet A, Jones M, Gatter KC, Mason DY. Megakaryocytes in myelodysplasia: an immunohistochemical study on bone marrow trephines. Histopathology 1990;17:69-74
    • (1990) Histopathology , vol.17 , pp. 69-74
    • Fox, S.B.1    Lorenzen, J.2    Heryet, A.3    Jones, M.4    Gatter, K.C.5    Mason, D.Y.6
  • 61
    • 0025248180 scopus 로고
    • Bone marrow biopsy in myelodysplastic syndromes: Morphological characteristics and contribution to the study of prognostic factors
    • Rios A, Canizo MC, Sanz MA, et al. Bone marrow biopsy in myelodysplastic syndromes: morphological characteristics and contribution to the study of prognostic factors. Br J Haematol 1990;75:26-33
    • (1990) Br J Haematol , vol.75 , pp. 26-33
    • Rios, A.1    Canizo, M.C.2    Sanz, M.A.3
  • 63
    • 0025261355 scopus 로고
    • An immunomorphometric study on megakaryocyte precursor cells in bone marrow tissue from patients with chronic myeloid leukemia (CML)
    • Thiele J, Wagner S, Weuste R, et al. An immunomorphometric study on megakaryocyte precursor cells in bone marrow tissue from patients with chronic myeloid leukemia (CML). Eur J Haematol 1990;44:63-70
    • (1990) Eur J Haematol , vol.44 , pp. 63-70
    • Thiele, J.1    Wagner, S.2    Weuste, R.3
  • 64
    • 0345707702 scopus 로고    scopus 로고
    • Bone marrow histopathology following cytoreductive therapy in chronic idiopathic myelofibrosis
    • Thiele J, Kvasnicka HM, Schmitt-Graeff A, Diehl V. Bone marrow histopathology following cytoreductive therapy in chronic idiopathic myelofibrosis. Histopathology 2003;43: 470-479
    • (2003) Histopathology , vol.43 , pp. 470-479
    • Thiele, J.1    Kvasnicka, H.M.2    Schmitt-Graeff, A.3    Diehl, V.4
  • 65
    • 24944520130 scopus 로고    scopus 로고
    • Essential thrombocythemia: Challenges and evidence-based management
    • Harrison CN. Essential thrombocythemia: challenges and evidence-based management. Br J Haematol 2005;130:153-165
    • (2005) Br J Haematol , vol.130 , pp. 153-165
    • Harrison, C.N.1
  • 66
    • 0032901326 scopus 로고    scopus 로고
    • Diagnostic criteria and prognosis in polycythemia vera and essential thrombocythemia
    • Murphy S. Diagnostic criteria and prognosis in polycythemia vera and essential thrombocythemia. Semin Hematol 1999;36: 9-13
    • (1999) Semin Hematol , vol.36 , pp. 9-13
    • Murphy, S.1
  • 67
    • 0031046485 scopus 로고    scopus 로고
    • Experience of the Polycythemia Vera Study Group with essential thrombocythemia: A final report on diagnostic criteria, survival, and leukemic transition by treatment
    • Murphy S, Peterson P, Hand H, Laszlo J. Experience of the Polycythemia Vera Study Group with essential thrombocythemia: a final report on diagnostic criteria, survival, and leukemic transition by treatment. Semin Hematol 1997;34: 29-39
    • (1997) Semin Hematol , vol.34 , pp. 29-39
    • Murphy, S.1    Peterson, P.2    Hand, H.3    Laszlo, J.4
  • 68
    • 0032322886 scopus 로고    scopus 로고
    • Diagnosis and classification of erythrocytoses and thrombocytoses
    • Pearson TC. Diagnosis and classification of erythrocytoses and thrombocytoses. Baillieres Clin Haematol 1998;11:695-720
    • (1998) Baillieres Clin Haematol , vol.11 , pp. 695-720
    • Pearson, T.C.1
  • 70
    • 0033656596 scopus 로고    scopus 로고
    • Relevance of bone marrow features in the differential diagnosis between essential thrombocythemia and early stage idiopathic myelofibrosis
    • Thiele J, Kvasnicka HM, Zankovich R, Diehl V. Relevance of bone marrow features in the differential diagnosis between essential thrombocythemia and early stage idiopathic myelofibrosis. Haematologica 2000;85:1126-1134
    • (2000) Haematologica , vol.85 , pp. 1126-1134
    • Thiele, J.1    Kvasnicka, H.M.2    Zankovich, R.3    Diehl, V.4
  • 71
    • 0038014047 scopus 로고    scopus 로고
    • Chronic myeloproliferative disorders with thrombocythemia: A comparative study of two classification systems (PVSG, WHO) on 839 patients
    • Thiele J, Kvasnicka HM. Chronic myeloproliferative disorders with thrombocythemia: a comparative study of two classification systems (PVSG, WHO) on 839 patients. Ann Hematol 2003;82:148-152
    • (2003) Ann Hematol , vol.82 , pp. 148-152
    • Thiele, J.1    Kvasnicka, H.M.2
  • 73
    • 85047687199 scopus 로고    scopus 로고
    • Evolution of myelofibrosis in chronic idiopathic myelofibrosis as evidenced in sequential bone marrow biopsy specimens
    • Buhr T, Busche G, Choritz H, Langer F, Kreipe H. Evolution of myelofibrosis in chronic idiopathic myelofibrosis as evidenced in sequential bone marrow biopsy specimens. Am J Clin Pathol 2003;119:152-158
    • (2003) Am J Clin Pathol , vol.119 , pp. 152-158
    • Buhr, T.1    Busche, G.2    Choritz, H.3    Langer, F.4    Kreipe, H.5
  • 74
    • 0032322879 scopus 로고    scopus 로고
    • The histopathology of chronic myeloproliferative diseases
    • Georgii A, Buesche G, Kreft A. The histopathology of chronic myeloproliferative diseases. Baillieres Clin Haematol 1998;11:721-749
    • (1998) Baillieres Clin Haematol , vol.11 , pp. 721-749
    • Georgii, A.1    Buesche, G.2    Kreft, A.3
  • 75
    • 0037409903 scopus 로고    scopus 로고
    • Dynamics of fibrosis in chronic idiopathic (primary) myelofibrosis during therapy: A follow-up study on 309 patients
    • Thiele J, Kvasnicka HM, Schmitt-Graeff A, Diehl V. Dynamics of fibrosis in chronic idiopathic (primary) myelofibrosis during therapy: a follow-up study on 309 patients. Leuk Lymphoma 2003;44:949-953
    • (2003) Leuk Lymphoma , vol.44 , pp. 949-953
    • Thiele, J.1    Kvasnicka, H.M.2    Schmitt-Graeff, A.3    Diehl, V.4
  • 76
    • 1842509221 scopus 로고    scopus 로고
    • Prefibrotic chronic idiopathic myelofibrosis - A diagnostic enigma?
    • Thiele J, Kvasnicka HM. Prefibrotic chronic idiopathic myelofibrosis-a diagnostic enigma? Acta Haematol 2004;111:155-159
    • (2004) Acta Haematol , vol.111 , pp. 155-159
    • Thiele, J.1    Kvasnicka, H.M.2
  • 77
    • 17144392554 scopus 로고    scopus 로고
    • The incidence of myelofibrosis in essential thrombocythaemia, polycythaemia vera and chronic idiopathic myelofibrosis: A retrospective evaluation of sequential bone marrow biopsies
    • Kreft A, Buche G, Ghalibafian M, Buhr T, Fischer T, Kirkpatrick CJ. The incidence of myelofibrosis in essential thrombocythaemia, polycythaemia vera and chronic idiopathic myelofibrosis: a retrospective evaluation of sequential bone marrow biopsies. Acta Haematol 2005;113:137-143
    • (2005) Acta Haematol , vol.113 , pp. 137-143
    • Kreft, A.1    Buche, G.2    Ghalibafian, M.3    Buhr, T.4    Fischer, T.5    Kirkpatrick, C.J.6
  • 78
    • 21644447311 scopus 로고    scopus 로고
    • Dynamics of bone marrow changes in patients with chronic idiopathic myelofibrosis following allogeneic stem cell transplantation
    • Thiele J, Kvasnicka HM, Dietrich H, et al. Dynamics of bone marrow changes in patients with chronic idiopathic myelofibrosis following allogeneic stem cell transplantation. Histol Histopathol 2005;20:879-889
    • (2005) Histol Histopathol , vol.20 , pp. 879-889
    • Thiele, J.1    Kvasnicka, H.M.2    Dietrich, H.3
  • 79
    • 33646496404 scopus 로고    scopus 로고
    • Clinicopathological criteria for differential diagnosis of thrombocythemias in various MPDs
    • Thiele J, Kvasnicka HM. Clinicopathological criteria for differential diagnosis of thrombocythemias in various MPDs. Semin Thromb Hemost 2006;32:219-230
    • (2006) Semin Thromb Hemost , vol.32 , pp. 219-230
    • Thiele, J.1    Kvasnicka, H.M.2
  • 80
    • 33745686453 scopus 로고    scopus 로고
    • The impact of clinicopathological studies in staging and survival in ET, PV and IMF
    • Kvasnicka HM, Thiele J. The impact of clinicopathological studies in staging and survival in ET, PV and IMF. Semin Thromb Hemost 2006;32:362-371
    • (2006) Semin Thromb Hemost , vol.32 , pp. 362-371
    • Kvasnicka, H.M.1    Thiele, J.2
  • 81
    • 25844509233 scopus 로고    scopus 로고
    • Bone marrow histopathology in myeloproliferative disorders - Current diagnostic approach
    • Thiele J, Kvasnicka HM, Orazi A. Bone marrow histopathology in myeloproliferative disorders - current diagnostic approach. Semin Hematol 2005;42:184-195
    • (2005) Semin Hematol , vol.42 , pp. 184-195
    • Thiele, J.1    Kvasnicka, H.M.2    Orazi, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.