메뉴 건너뛰기




Volumn 1, Issue 3, 2000, Pages 537-546

Anagrelide: A novel agent for the treatment of myeloproliferative disorders

Author keywords

Anagrelide; Dose; Mechanism of action; Myeloproliferative disorders; Pharmacokinetics; Toxicity

Indexed keywords

ANAGRELIDE; FIBRINOLYTIC AGENT; QUINAZOLINE DERIVATIVE;

EID: 0034157369     PISSN: 14656566     EISSN: None     Source Type: Journal    
DOI: 10.1517/14656566.1.3.537     Document Type: Review
Times cited : (33)

References (28)
  • 1
    • 0031578878 scopus 로고    scopus 로고
    • Anagrelide for essential thrombocythemia
    • Anagrelide for essential thrombocythemia. Med. Lett. (1997) 39(1016):120.
    • (1997) Med. Lett. , vol.39 , Issue.1016 , pp. 120
  • 2
    • 0030742530 scopus 로고    scopus 로고
    • Proposal for revised diagnostic criteria of essential thrombocythemia and polycythemia vera by the Thrombocythemia Vera Study Group
    • MICHIELS JJ, JUVONEN E: Proposal for revised diagnostic criteria of essential thrombocythemia and polycythemia vera by the Thrombocythemia Vera Study Group. Semin. Thromb. Hemost. (1997)23:339-347.
    • (1997) Semin. Thromb. Hemost. , vol.23 , pp. 339-347
    • Michiels, J.J.1    Juvonen, E.2
  • 3
    • 0033047249 scopus 로고    scopus 로고
    • Diagnosis, athogenesis and treatment of the myeloproliferative disorders essential thrombocythemia, polycythemia vera and myelofibrosis
    • MICHIELS JJ et al.: Diagnosis, athogenesis and treatment of the myeloproliferative disorders essential thrombocythemia, polycythemia vera and myelofibrosis. Neth. J. Med. (1999) 54:46-62.
    • (1999) Neth. J. Med. , vol.54 , pp. 46-62
    • Michiels, J.J.1
  • 4
    • 0032925412 scopus 로고    scopus 로고
    • Historical perspective on the treatment of essential thrombocythemia and polycythemia vera
    • GILBERT HS: Historical perspective on the treatment of essential thrombocythemia and polycythemia vera Semin. Hematol. (1999) 36(1):19-22. A historical review of the treatment of ET and PV.
    • (1999) Semin. Hematol. , vol.36 , Issue.1 , pp. 19-22
    • Gilbert, H.S.1
  • 5
    • 0032956569 scopus 로고    scopus 로고
    • Introduction: Overview of chronic myeloproliferative disorders
    • TEFFERI A: Introduction: overview of chronic myeloproliferative disorders. Semin. Hematol. (1999) 36(1):1-2.
    • (1999) Semin. Hematol. , vol.36 , Issue.1 , pp. 1-2
    • Tefferi, A.1
  • 6
    • 0030803837 scopus 로고    scopus 로고
    • Anagrelide as a new platelet-lowering agent in essential thrombocythemia: Mechanism of action, efficacy, toxicity, current indications
    • TERRERI A, SILVERSTEIN MN, PETITT RM et al.: Anagrelide as a new platelet-lowering agent in essential thrombocythemia: mechanism of action, efficacy, toxicity, current indications. Semin. Thromb. Hemost (1997) 23(4)579-382.
    • (1997) Semin. Thromb. Hemost , vol.23 , Issue.4 , pp. 579-1382
    • Terreri, A.1    Silverstein, M.N.2    Petitt, R.M.3
  • 7
    • 0031041044 scopus 로고    scopus 로고
    • From efficacy to safety: A Polycythemia Vera Study Group report on hydroxyurea in patients with polycythemia vera
    • FRUCHTMAN SM, MACK K, KAPLAN ME et al.: From efficacy to safety: a Polycythemia Vera Study Group report on hydroxyurea in patients with polycythemia vera. Semin. Hematol. (1997) 34(1):17-23. The PVSG report on the use of HU for PV.
    • (1997) Semin. Hematol. , vol.34 , Issue.1 , pp. 17-23
    • Fruchtman, S.M.1    Mack, K.2    Kaplan, M.E.3
  • 9
    • 0031938061 scopus 로고    scopus 로고
    • Treatment of polycythemia vera
    • BARBUI T, FINAZZI G: Treatment of polycythemia vera. Haematologica (1998) 83:143-149.
    • (1998) Haematologica , vol.83 , pp. 143-149
    • Barbui, T.1    Finazzi, G.2
  • 10
    • 0026802121 scopus 로고
    • Primary thrombocythemia: New drugs for an evolving disease
    • BALDUINI CL: Primary thrombocythemia: new drugs for an evolving disease. Haematologica (1992) 77:297-301.
    • (1992) Haematologica , vol.77 , pp. 297-301
    • Balduini, C.L.1
  • 11
    • 0019515836 scopus 로고
    • Disposition of anagrelide, an inhibitor of platelet aggregation
    • GAVER RC, DEED G, PITTMAN KA et al.: Disposition of anagrelide, an inhibitor of platelet aggregation. Clin. Pharmacol. Ther. (1981) 29(3):381-386. A description of the metabolism of anagrelide.
    • (1981) Clin. Pharmacol. Ther. , vol.29 , Issue.3 , pp. 381-386
    • Gaver, R.C.1    Deed, G.2    Pittman, K.A.3
  • 12
    • 0032979613 scopus 로고    scopus 로고
    • Efficacy, safety and tolerability of anagrelide in the treatment of essential thrombocythemia
    • MILLS AK, TAYLOR KM, WRIGHT SJ et al.: Efficacy, safety and tolerability of anagrelide in the treatment of essential thrombocythemia Aust. NZ J. Med. (1999) 29:29-35.
    • (1999) Aust. NZ J. Med. , vol.29 , pp. 29-35
    • Mills, A.K.1    Taylor, K.M.2    Wright, S.J.3
  • 13
    • 0023513088 scopus 로고
    • Effects of anagrelide on platelet cAMP levels, cAMP-dependent protein kinase and thrombin-induced Ca fluxes
    • SEILER S, ARNOLD AJ, GROVE RI et al.: Effects of anagrelide on platelet cAMP levels, cAMP-dependent protein kinase and thrombin-induced Ca fluxes. J. Pharmacol. Exp. Ther. (1987) 243:767-773.
    • (1987) J. Pharmacol. Exp. Ther. , vol.243 , pp. 767-773
    • Seiler, S.1    Arnold, A.J.2    Grove, R.I.3
  • 14
    • 9844256082 scopus 로고    scopus 로고
    • The effects of anagrelide on human megakaryocytopoiesis
    • SOLBERG LA, TEFFERI A, OLES KJ et al.: The effects of anagrelide on human megakaryocytopoiesis. Br. J. Haematol. (1997) 99:174-180.
    • (1997) Br. J. Haematol. , vol.99 , pp. 174-180
    • Solberg, L.A.1    Tefferi, A.2    Oles, K.J.3
  • 15
    • 0032190424 scopus 로고    scopus 로고
    • Anagrelide, a selective thrombocytopenic agent
    • OERTEL MD: Anagrelide, a selective thrombocytopenic agent. Am. J. Health Syst. Pharm. (1998) 55:1979-1986. A drug evaluation of anagrelide with literature review.
    • (1998) Am. J. Health Syst. Pharm. , vol.55 , pp. 1979-1986
    • Oertel, M.D.1
  • 16
    • 0033003618 scopus 로고    scopus 로고
    • Studies of platelet volume, chemistry and function in patients with essential thrombocythemia treated with anagrelide
    • BELLUCCI S, LEGRAND C, BOVAL B et al.: Studies of platelet volume, chemistry and function in patients with essential thrombocythemia treated with anagrelide Br. J. Haematol. (1999) 104:886-892.
    • (1999) Br. J. Haematol. , vol.104 , pp. 886-892
    • Bellucci, S.1    Legrand, C.2    Boval, B.3
  • 17
    • 2542505252 scopus 로고    scopus 로고
    • Roberts Pharmaceutical Corp., Eatontown, NJ, USA
    • Agrylin package insert. Roberts Pharmaceutical Corp., Eatontown, NJ, USA (1997).
    • (1997) Agrylin Package Insert
  • 18
    • 0026639799 scopus 로고
    • Analysis of the mechanism of anagrelide-induced thrombocytopenia in humans
    • MAZUR EM, ROSMARIN AG, SOHL PA et al.: Analysis of the mechanism of anagrelide-induced thrombocytopenia in humans. Blood (1992) 79(8):1931-1937.
    • (1992) Blood , vol.79 , Issue.8 , pp. 1931-1937
    • Mazur, E.M.1    Rosmarin, A.G.2    Sohl, P.A.3
  • 19
    • 0037483282 scopus 로고
    • Anagrelide, a therapy for thrombocythemic states: Experience in 577 patients
    • ANAGRELIDE STUDY GROUP: Anagrelide, a therapy for thrombocythemic states: experience in 577 patients. Am. J. Med. (1992) 92:69-78. A large, multicentre trial.
    • (1992) Am. J. Med. , vol.92 , pp. 69-78
  • 20
    • 0028357051 scopus 로고
    • Anagrelide: A review of its pharmacodynamics and pharmacokinetic properties, and therapeutic potential in the treatment of thrombocythemia
    • SPENCER CM, BROGDEN RN: Anagrelide: a review of its pharmacodynamics and pharmacokinetic properties, and therapeutic potential in the treatment of thrombocythemia. Drugs (1994) 47(6):809-822. A comprehensive evaluation of anagrelide.
    • (1994) Drugs , vol.47 , Issue.6 , pp. 809-822
    • Spencer, C.M.1    Brogden, R.N.2
  • 21
    • 0021709130 scopus 로고
    • Inhibition of platelet production induced by an antiplatelet drug, anagrelide, in normal volunteers
    • ANDES WA, NOVECK J, FLEMING JS: Inhibition of platelet production induced by an antiplatelet drug, anagrelide, in normal volunteers. Thromb. Haemost. (1984) 52(3):325-328.
    • (1984) Thromb. Haemost. , vol.52 , Issue.3 , pp. 325-328
    • Andes, W.A.1    Noveck, J.2    Fleming, J.S.3
  • 22
    • 0031047572 scopus 로고    scopus 로고
    • Anagrelidc for control of thrombocythemia in polycythemia and other myeloproliferative disorders
    • PETITT RM, MURRAY N, SILVERSTEIN MN et al.: Anagrelidc for control of thrombocythemia in polycythemia and other myeloproliferative disorders. Semin. Hematol. (1997) 34(1):51-54.
    • (1997) Semin. Hematol. , vol.34 , Issue.1 , pp. 51-54
    • Petitt, R.M.1    Murray, N.2    Silverstein, M.N.3
  • 23
    • 0003707382 scopus 로고    scopus 로고
    • Medical Economics Co.
    • Red Book. Medical Economics Co. (1999):173.
    • (1999) Red Book , pp. 173
  • 24
    • 0033029715 scopus 로고    scopus 로고
    • Spontaneous remission of anemia associated with a myelodysplastic syndrome with disease evolution into a mycloproliferative state
    • TEFFERI A, INWARDS DJ, HOYER JD: Spontaneous remission of anemia associated with a myelodysplastic syndrome with disease evolution into a mycloproliferative state. Acta Haematologica (1999) 101:50-52.
    • (1999) Acta Haematologica , vol.101 , pp. 50-52
    • Tefferi, A.1    Inwards, D.J.2    Hoyer, J.D.3
  • 25
    • 0030792954 scopus 로고    scopus 로고
    • Precipitous fall in platelet count with anagrelide: Case report and critique of dosing recommendations
    • MCCUNE JS, LILES D, LINDLEY C: Precipitous fall in platelet count with anagrelide: case report and critique of dosing recommendations. Pharmacotherapy (1997) 17(4):822-826. A case report and critique of anagrelide dosing recommendations.
    • (1997) Pharmacotherapy , vol.17 , Issue.4 , pp. 822-826
    • Mccune, J.S.1    Liles, D.2    Lindley, C.3
  • 26
    • 0023946455 scopus 로고
    • Anagrelide: A new drug for treating thrombocytosis
    • SILVERSTEIN MN, PETITT RM, SOLBERG LA et al.: Anagrelide: a new drug for treating thrombocytosis. N. Engl. J. Med. (1988) 318(20):1292-1294.
    • (1988) N. Engl. J. Med. , vol.318 , Issue.20 , pp. 1292-1294
    • Silverstein, M.N.1    Petitt, R.M.2    Solberg, L.A.3
  • 27
    • 0026785698 scopus 로고
    • Therapy with anagrelide in patients affected by essential thrombocythemia: Preliminary results
    • MAZZUCCONI MG, DESANCTIS V, CHISTOLINI A et al.: Therapy with anagrelide in patients affected by essential thrombocythemia: preliminary results. Haematologica (1992) 77:315-317.
    • (1992) Haematologica , vol.77 , pp. 315-317
    • Mazzucconi, M.G.1    Desanctis, V.2    Chistolini, A.3
  • 28
    • 0026576978 scopus 로고
    • Effect of anagrelide on platelet count and function in patients with thrombocytosis and myeloproliferative disorders
    • BALDUINI CL, BERTOLINO G, NORIS P et al.: Effect of anagrelide on platelet count and function in patients with thrombocytosis and myeloproliferative disorders. Haematologica (1992) 77:40-43.
    • (1992) Haematologica , vol.77 , pp. 40-43
    • Balduini, C.L.1    Bertolino, G.2    Noris, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.