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Volumn 98, Issue 2, 2006, Pages 440-444

Penicillamine administration reverses the inhibitory effect of hyperhomocysteinaemia on endothelium-dependent relaxation in the corpus cavernosum in the rabbit

Author keywords

Copper; Erectile dysfunction; Homocysteine; Penicillamine; Rabbit

Indexed keywords

CHELATING AGENT; COPPER; HOMOCYSTEINE; HYDROGEN PEROXIDE; METHIONINE; NITRIC OXIDE; PENICILLAMINE; PEROXYNITRITE; PHENYLEPHRINE;

EID: 33745684220     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2006.06212.x     Document Type: Article
Times cited : (18)

References (38)
  • 1
    • 0035987777 scopus 로고    scopus 로고
    • Effects of sildenafil on erectile activity in mice lacking neuronal or endothelial nitric oxide synthase
    • Cashen DE, MacIntyre DE, Martin WJ. Effects of sildenafil on erectile activity in mice lacking neuronal or endothelial nitric oxide synthase. Br J Pharmacol 2002; 136: 693-700
    • (2002) Br J Pharmacol , vol.136 , pp. 693-700
    • Cashen, D.E.1    MacIntyre, D.E.2    Martin, W.J.3
  • 2
    • 0032792815 scopus 로고    scopus 로고
    • Nitric oxide and the cyclic GMP system in the penis
    • Gonzalez-Cadavid NF, Ignarro U, Rajfer J. Nitric oxide and the cyclic GMP system in the penis. Mol Urol 1999; 3: 51-9
    • (1999) Mol Urol , vol.3 , pp. 51-59
    • Gonzalez-Cadavid, N.F.1    Ignarro, U.2    Rajfer, J.3
  • 3
    • 0031403328 scopus 로고    scopus 로고
    • Effects of sildenafil, a type-5 cGMP phosphodiesterase inhibitor, and papaverine on cyclic GMP and cyclic AMP levels in the rabbit corpus cavernosum in vitro
    • Jeremy JY, Ballard S, Naylor A, Miller MAW, Angelini GD. Effects of sildenafil, a type-5 cGMP phosphodiesterase inhibitor, and papaverine on cyclic GMP and cyclic AMP levels in the rabbit corpus cavernosum in vitro. Br J Urol 1997; 79: 958-63
    • (1997) Br J Urol , vol.79 , pp. 958-963
    • Jeremy, J.Y.1    Ballard, S.2    Naylor, A.3    Miller, M.A.W.4    Angelini, G.D.5
  • 4
    • 0033566591 scopus 로고    scopus 로고
    • Nitric oxide and penile erection: Is erectile dysfunction another manifestation of vascular disease?
    • Sullivan ME, Thompson CS, Dashwood MR et al. Nitric oxide and penile erection: is erectile dysfunction another manifestation of vascular disease? Cardiovasc Res 1999; 43: 658-65
    • (1999) Cardiovasc Res , vol.43 , pp. 658-665
    • Sullivan, M.E.1    Thompson, C.S.2    Dashwood, M.R.3
  • 5
    • 0034099331 scopus 로고    scopus 로고
    • Platelets, oxidant stress and erectile dysfunction: An hypothesis
    • Jeremy JY, Angelini GD, Khan M et al. Platelets, oxidant stress and erectile dysfunction: an hypothesis. Cardiovasc Res 2000; 46: 50-4
    • (2000) Cardiovasc Res , vol.46 , pp. 50-54
    • Jeremy, J.Y.1    Angelini, G.D.2    Khan, M.3
  • 7
    • 0035154347 scopus 로고    scopus 로고
    • The effect of superoxide dismutase on nitric oxide-mediated and electrical field-stimulated diabetic rabbit cavernosal smooth muscle relaxation
    • Khan MA, Thompson CS, Jeremy JY, Mumtaz FH, Mikhailidis P, Morgan RJ. The effect of superoxide dismutase on nitric oxide-mediated and electrical field-stimulated diabetic rabbit cavernosal smooth muscle relaxation. BJU Int 2001; 87: 98-103
    • (2001) BJU Int , vol.87 , pp. 98-103
    • Khan, M.A.1    Thompson, C.S.2    Jeremy, J.Y.3    Mumtaz, F.H.4    Mikhailidis, P.5    Morgan, R.J.6
  • 8
    • 0035800567 scopus 로고    scopus 로고
    • The effect of sildenafil on corpus cavernosal smooth muscle relaxation and cyclic GMP formation in the diabetic rabbit
    • Thompson CS, Mumtaz FH, Khan MA et al. The effect of sildenafil on corpus cavernosal smooth muscle relaxation and cyclic GMP formation in the diabetic rabbit. Eur J Pharmacol 2001; 425: 57-64
    • (2001) Eur J Pharmacol , vol.425 , pp. 57-64
    • Thompson, C.S.1    Mumtaz, F.H.2    Khan, M.A.3
  • 10
    • 0030188563 scopus 로고    scopus 로고
    • The oxidant stress of hyperhomocysteinaemia
    • Loscalzo J. The oxidant stress of hyperhomocysteinaemia. J Clin Invest 1996; 98: 5-7
    • (1996) J Clin Invest , vol.98 , pp. 5-7
    • Loscalzo, J.1
  • 11
    • 12544257407 scopus 로고    scopus 로고
    • Cavernosal dysfunction in a rabbit model of hyperhomocysteinaemia
    • Jones RW, Jeremy JY, Koupparis A, Persad R, Shukla N. Cavernosal dysfunction in a rabbit model of hyperhomocysteinaemia. BJU Int 2005; 95: 125-30
    • (2005) BJU Int , vol.95 , pp. 125-130
    • Jones, R.W.1    Jeremy, J.Y.2    Koupparis, A.3    Persad, R.4    Shukla, N.5
  • 12
    • 0009715206 scopus 로고    scopus 로고
    • Investigation of the inhibitory effects of homocysteine and copper on nitric oxide-mediated relaxation of rat isolated aorta
    • Emsley AM, Jeremy JY, Gomes GN, Angelini GD, Plane F. Investigation of the inhibitory effects of homocysteine and copper on nitric oxide-mediated relaxation of rat isolated aorta. Br J Pharmacol 1999; 126: 1034-40
    • (1999) Br J Pharmacol , vol.126 , pp. 1034-1040
    • Emsley, A.M.1    Jeremy, J.Y.2    Gomes, G.N.3    Angelini, G.D.4    Plane, F.5
  • 13
    • 0343898646 scopus 로고    scopus 로고
    • The interaction of homocysteine and copper markedly inhibits the relaxation of rabbit corpus cavernosum: New risk factors for angiopathic erectile dysfunction?
    • Khan MA, Thompson CS, Emsley AM et al. The interaction of homocysteine and copper markedly inhibits the relaxation of rabbit corpus cavernosum: new risk factors for angiopathic erectile dysfunction? BJU Int 1999; 84: 720-4
    • (1999) BJU Int , vol.84 , pp. 720-724
    • Khan, M.A.1    Thompson, C.S.2    Emsley, A.M.3
  • 14
    • 10744233748 scopus 로고    scopus 로고
    • High-dose versus low-dose D-penicillamine in early diffuse systemic sclerosis trial: Lessons learned
    • Clements PJ, Seibold JR, Furst DE et al. High-dose versus low-dose D-penicillamine in early diffuse systemic sclerosis trial: lessons learned. Semin Arthritis Rheum 2004; 33: 249-63
    • (2004) Semin Arthritis Rheum , vol.33 , pp. 249-263
    • Clements, P.J.1    Seibold, J.R.2    Furst, D.E.3
  • 15
  • 17
    • 0033936128 scopus 로고    scopus 로고
    • Serum copper concentration and coronary heart disease among US adults
    • Ford ES. Serum copper concentration and coronary heart disease among US adults. Am J Epidemiol 2000; 151: 1182-8
    • (2000) Am J Epidemiol , vol.151 , pp. 1182-1188
    • Ford, E.S.1
  • 18
    • 0035477031 scopus 로고    scopus 로고
    • A critical overview of the chemistry of copper-dependent low density lipoprotein oxidation: Roles of lipid hydroperoxides, alpha-tocopherol, thiols, and ceruloplasmin
    • Burkitt MJ. A critical overview of the chemistry of copper-dependent low density lipoprotein oxidation: roles of lipid hydroperoxides, alpha-tocopherol, thiols, and ceruloplasmin. Arch Biochem Biophys 2001; 394: 117-35
    • (2001) Arch Biochem Biophys , vol.394 , pp. 117-135
    • Burkitt, M.J.1
  • 19
    • 0034793688 scopus 로고    scopus 로고
    • The Haber-Weiss cycle - 70 years on
    • Koppenol WH. The Haber-Weiss cycle - 70 years on. Redox Rep 2001; 6: 229-34
    • (2001) Redox Rep , vol.6 , pp. 229-234
    • Koppenol, W.H.1
  • 20
    • 0027437209 scopus 로고
    • The centennial of the Fenton reaction
    • Koppenol WH. The centennial of the Fenton reaction. Free Radic Biol Med 1993; 15: 645-51
    • (1993) Free Radic Biol Med , vol.15 , pp. 645-651
    • Koppenol, W.H.1
  • 22
    • 33745724046 scopus 로고    scopus 로고
    • Hypercholesterolaemia and erectile dysfunction: Role of superoxide generating enzymes and effect of a NO donating sildenafil derivative, NCX 911
    • in press
    • Shukla N, Jones R, Persad R, Angelini GD, Jeremy JY. Hypercholesterolaemia and erectile dysfunction: role of superoxide generating enzymes and effect of a NO donating sildenafil derivative, NCX 911. Eur J Pharmacol 2005; in press
    • (2005) Eur J Pharmacol
    • Shukla, N.1    Jones, R.2    Persad, R.3    Angelini, G.D.4    Jeremy, J.Y.5
  • 23
    • 33745724047 scopus 로고    scopus 로고
    • Sildenafil inhibits the formation of superoxide and the expression of gp47phox NADPH oxidase induced by the thromboxane A2 mimetic, U46619, in corpus cavernosal smooth muscle cells
    • in press
    • Kouparris A, Muzaffar S, Jeremy JY, Angelini GD, Shukla N. Sildenafil inhibits the formation of superoxide and the expression of gp47phox NADPH oxidase induced by the thromboxane A2 mimetic, U46619, in corpus cavernosal smooth muscle cells. BJU Int 2006; in press
    • (2006) BJU Int
    • Kouparris, A.1    Muzaffar, S.2    Jeremy, J.Y.3    Angelini, G.D.4    Shukla, N.5
  • 25
    • 0036820952 scopus 로고    scopus 로고
    • Copper chaperones: Personal escorts for metal ions
    • Field LS, Luk E, Culotta VC. Copper chaperones: personal escorts for metal ions. J Bioenerg Biomembr 2002; 34: 373-9
    • (2002) J Bioenerg Biomembr , vol.34 , pp. 373-379
    • Field, L.S.1    Luk, E.2    Culotta, V.C.3
  • 26
    • 0028346793 scopus 로고
    • Peroxynitrite releases copper from caeruloplasmin: Implications for atherosclerosis
    • Swain JA, Darley-Usmar V, Gutteridge JM. Peroxynitrite releases copper from caeruloplasmin: implications for atherosclerosis. FEBS Lett 1994; 342: 49-52
    • (1994) FEBS Lett , vol.342 , pp. 49-52
    • Swain, J.A.1    Darley-Usmar, V.2    Gutteridge, J.M.3
  • 27
    • 0343963169 scopus 로고    scopus 로고
    • Ceruloplasmin enhances DNA damage induced by hydrogen peroxide in vitro
    • Kim RH, Park JE, Park JW. Ceruloplasmin enhances DNA damage induced by hydrogen peroxide in vitro. Free Radic Res 2000; 33: 81-9
    • (2000) Free Radic Res , vol.33 , pp. 81-89
    • Kim, R.H.1    Park, J.E.2    Park, J.W.3
  • 28
    • 0032875183 scopus 로고    scopus 로고
    • On the lability and functional significance of the type I copper pool in ceruloplasmin
    • Musci G, Fraterrigo TZ, Calabrese L, McMillin DR. On the lability and functional significance of the type I copper pool in ceruloplasmin. J Biol Inorg Chem 1999; 4: 441-6
    • (1999) J Biol Inorg Chem , vol.4 , pp. 441-446
    • Musci, G.1    Fraterrigo, T.Z.2    Calabrese, L.3    McMillin, D.R.4
  • 29
    • 0034144361 scopus 로고    scopus 로고
    • Fragmentation of human ceruloplasmin induced by hydrogen peroxide
    • Choi SY, Kwon HY, Kwon OB, Eum WS, Kang JH. Fragmentation of human ceruloplasmin induced by hydrogen peroxide. Biochimie 2000; 82: 175-80
    • (2000) Biochimie , vol.82 , pp. 175-180
    • Choi, S.Y.1    Kwon, H.Y.2    Kwon, O.B.3    Eum, W.S.4    Kang, J.H.5
  • 31
    • 0029968126 scopus 로고    scopus 로고
    • Role of Fenton chemistry in thiol-induced toxicity and apoptosis
    • Held KD, Sylvester FC, Hopcia KL, Biaglow JE. Role of Fenton chemistry in thiol-induced toxicity and apoptosis. Radiat Res 1996; 145: 542-53
    • (1996) Radiat Res , vol.145 , pp. 542-553
    • Held, K.D.1    Sylvester, F.C.2    Hopcia, K.L.3    Biaglow, J.E.4
  • 32
    • 0032882504 scopus 로고    scopus 로고
    • Mechanism of copper-catalyzed autoxidation of cysteine
    • Kachur AV, Koch CJ, Biaglow JE. Mechanism of copper-catalyzed autoxidation of cysteine. Free Radic Res 1999; 31: 23-34
    • (1999) Free Radic Res , vol.31 , pp. 23-34
    • Kachur, A.V.1    Koch, C.J.2    Biaglow, J.E.3
  • 33
    • 0031842534 scopus 로고    scopus 로고
    • Mechanism of copper-catalyzed oxidation of glutathione
    • Kachur AV, Koch CJ, Biaglow JE. Mechanism of copper-catalyzed oxidation of glutathione. Free Radic Res 1998; 28: 259-69
    • (1998) Free Radic Res , vol.28 , pp. 259-269
    • Kachur, A.V.1    Koch, C.J.2    Biaglow, J.E.3
  • 34
    • 0030801910 scopus 로고    scopus 로고
    • The cell-damaging effects of low amounts of homocysteine and copper ions in human cell line cultures are caused by oxidative stress
    • Hultberg B, Andersson A, Isaksson A. The cell-damaging effects of low amounts of homocysteine and copper ions in human cell line cultures are caused by oxidative stress. Toxicology 1997; 123: 33-40
    • (1997) Toxicology , vol.123 , pp. 33-40
    • Hultberg, B.1    Andersson, A.2    Isaksson, A.3
  • 35
    • 0028934992 scopus 로고
    • Structure, oxidant activity, and cardiovascular mechanisms of human caeruloplasmin
    • Fox PL, Mukhopadhyay C, Ehrenwald E. Structure, oxidant activity, and cardiovascular mechanisms of human caeruloplasmin. Life Sci 1995; 56: 1749-58
    • (1995) Life Sci , vol.56 , pp. 1749-1758
    • Fox, P.L.1    Mukhopadhyay, C.2    Ehrenwald, E.3
  • 36
    • 4544378858 scopus 로고    scopus 로고
    • Low micromolar concentrations of copper augment the impairment of endothelium-dependent relaxation of aortae from diabetic rabbits
    • Shukla N, Thompson C, Angelini GD, Mikhailidis DP, Jeremy JY. Low micromolar concentrations of copper augment the impairment of endothelium-dependent relaxation of aortae from diabetic rabbits. Metabolism 2004; 53: 1315-21
    • (2004) Metabolism , vol.53 , pp. 1315-1321
    • Shukla, N.1    Thompson, C.2    Angelini, G.D.3    Mikhailidis, D.P.4    Jeremy, J.Y.5
  • 37
    • 0141799951 scopus 로고    scopus 로고
    • Tetrathiomolybdate anticopper therapy for Wilson's disease inhibits angiogenesis, fibrosis and inflammation
    • Brewer GJ. Tetrathiomolybdate anticopper therapy for Wilson's disease inhibits angiogenesis, fibrosis and inflammation. J Cell Mol Med 2003; 7: 11-20
    • (2003) J Cell Mol Med , vol.7 , pp. 11-20
    • Brewer, G.J.1
  • 38
    • 0036784521 scopus 로고    scopus 로고
    • Effects of folate treatment and homocysteine lowering on resistance vessel reactivity in atherosclerotic subjects
    • Stanger O, Semmelrock HJ, Wonisch W, Bos U, Pabst E, Wascher TC. Effects of folate treatment and homocysteine lowering on resistance vessel reactivity in atherosclerotic subjects. J Pharmacol Exp Ther 2002; 303: 158-62
    • (2002) J Pharmacol Exp Ther , vol.303 , pp. 158-162
    • Stanger, O.1    Semmelrock, H.J.2    Wonisch, W.3    Bos, U.4    Pabst, E.5    Wascher, T.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.