Altered endothelin-1 vasoreactivity in patients with untreated normal-pressure glaucoma

Investigative Ophthalmology and Visual Science

Volumn 47, Issue 6, 2006, Pages 2528-2532

  Henry, Emer ^a   Newby, David E ^b   Webb, David J ^b   Hadoke, Patrick W F ^b   O'Brien, Colm J ^c  

^a PRINCESS ALEXANDRA EYE PAVILION   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c Mater Hospital   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; NITRIC OXIDE; CYCLO(TRP ASP PRO VAL LEU); CYCLO(TRP-ASP-PRO-VAL-LEU); CYCLOPEPTIDE;

ADULT; AGED; ARTICLE; BLOOD PRESSURE MEASUREMENT; BLOOD VESSEL REACTIVITY; CLINICAL ARTICLE; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FEMALE; FOREARM BLOOD FLOW; GLAUCOMA; HEART RATE; HUMAN; MALE; PERIPHERAL CIRCULATION; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RADIOIMMUNOASSAY; VASODILATATION; VEIN OCCLUSION PLETHYSMOGRAPHY; BLOOD; BLOOD FLOW VELOCITY; BLOOD PRESSURE; DRUG ANTAGONISM; FOREARM; INTRAOCULAR PRESSURE; MIDDLE AGED; OPEN ANGLE GLAUCOMA; PATHOPHYSIOLOGY; PHYSIOLOGY; VASCULAR ENDOTHELIUM; VASCULARIZATION;

BLOOD FLOW VELOCITY; BLOOD PRESSURE; ENDOTHELIN-1; ENDOTHELIUM, VASCULAR; FEMALE; FOREARM; GLAUCOMA, OPEN-ANGLE; HEART RATE; HUMANS; INTRAOCULAR PRESSURE; MALE; MIDDLE AGED; PEPTIDES, CYCLIC; RADIOIMMUNOASSAY; RECEPTOR, ENDOTHELIN A; VASODILATION;

EID: 33745656230     PISSN: 01460404     EISSN: None     Source Type: Journal    
DOI: 10.1167/iovs.05-0240     Document Type: Article

References (58)

1. Cursiefen C, Wisse M, Cursiefen S, et al. Migraine and tension headache in high-pressure and normal-pressure glaucoma. Am J Ophthalmol. 2000;129:102-104.
2. Guthauser U, Flammer J, Mahler F. The relationship between digital and ocular vasospasm. Graefes Arch Clin Exp Ophthalmol. 1988;226:224-226.
3. Gasser P, Flammer J, Guthauser U, et al. Do vasospasms provoke ocular diseases? Angiology. 1990;41:213-220.
4. Butt Z, O'Brien C, McKillop G, et al. Color Doppler imaging in untreated high and normal pressure open angle glaucoma. Invest Ophthalmol Vis Sci. 1997;38:690-696.
5. Harris A, Sergott RC, Spaeth GL, et al. Color Doppler analysis of ocular vessel blood velocity in normal-tension glaucoma. Am J Ophthalmol. 1994;118:642-649.
6. Drance SM, Douglas GR, Wijsman K, et al. Response of blood flow to warm and cold in normal and low-tension glaucoma patients. Am J Ophthalmol. 1988;105:35-39.
7. Gasser P, Flammer J. Blood cell velocity in the nailfold capillaries of patients with normal tension and high tension glaucoma. Am J Ophthalmol. 1991;111:585-588.
8. Dowd P. Raynaud's phenomenon. Lancet. 1995;346:283-290.
9. Walmsley D, Goodfield MJD. Evidence for an abnormal peripherally mediated vascular response to temperature in Raynaud's phenomenon. Br J Rheumatol. 1995;29:181-184.
10. Gasser P. Clinical syndromes with vasoconstrictor response. Wien Klin Wochenschr. 1991;103:217-221.
11. Luscher TF, Boulanger CM, Yang Z, et al. Interactions between endothelium-derived relaxing and contracting factors in health and cardiovascular disease. Circulation. 1993;87(suppl):36-44.
12. Parris RJ, Webb DJ. The endothelin system in cardiovascular physiology and pathophysiology. Vasc Med. 1997;2:31-43.
13. Haynes WG, Strachan FE, Webb DJ. Endothelin ETA and ETB receptors cause vasoconstriction of human resistance and capacitance vessels in vivo. Circulation. 1995;92:357-363.
14. Verhaar MC, Strachan FE, Newby DE, et al. Endothelin-A receptor antagonist-mediated vasodilatation is attenuated by inhibition of nitric oxide synthesis and by endothelin-B receptor blockade. Circulation. 1998;97:752-756.
15. Haynes WG, Webb DJ. Contribution of endogenous generation of endothelin-1 to basal vascular tone. The Lancet. 1994;344:852-854.
16. Haynes WG, Ferro CJ, O'Kane KPJ, et al. Systemic endothelin receptor blockade decreases peripheral vascular resistance and blood pressure in man. Circulation. 1996;93:1860-1870.
17. Toyo-oka T, Aizawa T, Suzuki N. Increased plasma levels of endothelin-1 and coronary vasospasm induction in patients with vasospastic angina pectoris. Circulation. 1991;83:476-483.
18. Suzuki R, Masaoka H, Hirata Y, et al. The role of endothelin-1 in the origin of cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage. J Neurosurg. 1992;77:96-100.
19. Zimmermann M. Endothelin in cerebral vasospasm: clinical and experimental results. J Neurosurg Sci. 1997;41:139-151.
20. Zamora MR, O'Brien RF, Rutherford RB, et al. Serum endothelin-1 concentrations and cold provocation in primary Raynaud's phenomenon. Lancet. 1990;336:1144-1147.
21. Sugiyama T, Moriya S, Oku H, et al. Association of endothelin-1 with normal tension glaucoma: clinical and fundamental studies. Surv Ophthalmol. 1995;30:S49-S56.
22. Cellini M, Possati GL, Profazio V, et al. Color Doppler imaging and plasma levels of endothelin-1 in low-tension glaucoma. Acta Ophthalmol Scand. 1997;(suppl):11-13.
23. Kaiser HJ, Flammer J, Wenk M, et al. Endothelin-1 plasma levels in normal-tension glaucoma: abnormal response to postural changes. Graefes Arch Clin Exp Ophthalmol. 1995;233:484-488.
24. Nicolela MT, Ferrier SN, Morrison CA, et al. Effects of cold-induced vasospasm in glaucoma: the role of endothelin-1. Invest Ophthalmol Vis Sci. 2003;44:2565-2572.
25. Henry E, Newby DE, Webb DJ, et al. Peripheral endothelial dysfunction in normal pressure glaucoma. Invest Ophthalmol Vis Sci. 1999;40:1710-1714.
26. Cleary C, Buckley CH, Henry E, et al. Enhanced endothelium-derived hyperpolarising factor activity in resistance arteries from normal pressure glaucoma patients: implications for vascular function in the eye. Br J Ophthalmol. 2005;89:223-228.
27. Buckley CH, Hadoke PWF, Henry E, et al. Systemic vascular endothelial cell dysfunction in normal pressure glaucoma. Br J Ophthalmol. 2002;86:227-232.
28. Benjamin N, Calver A, Collier J, et al. Measuring forearm blood flow and interpreting the responses to drugs and mediators. Hypertension. 1995;25:918-923.
29. Rolinski B, Sadri I, Bogner J, et al. Determination of endothelin-1 immunoreactivity in plasma, cerebrospinal fluid and urine. Res Exp Med (Berl). 1994;194:9-24.
30. Newby D. Intra-arterial substance P mediated vasodilation in the human forearm: pharmacology, reproducibility and tolerability. Br J Pharmacol. 1997;43:493-499.
31. Newby D, Flint K, Boon N, et al. Reduced responsiveness to endothelin-1 in peripheral resistance vessels of patients with Syndrome X. J Am Coll Cardiol. 1998;31:1585-1590.
32. Cody RJ, Haas GJ, Binkley PF, et al. Plasma endothelin correlates with the extent of pulmonary hypertension in patients with chronic congestive heart failure. Circulation. 1992;85:504-509.
33. Takahashi K, Ghatei MA, Lam HC, et al. Elevated plasma endothelin in patients with diabetes mellitus. Diabetologia. 1990;33:306-310.
34. Gallai V, Sacheilli P, Firenze C. Endothelin-1 in migraine and tension-type headache. Acta Neurol Scand. 1994;89:47-55.
35. Matsuyama K, Yashue H, Okumura K. Increased plasma levels of endothelin-1 like immunoreactivity during coronary vasospasm in patients with coronary spastic angina. Am J Cardiol. 1991;68:991-995.
36. Fyhrquist F, Saijonmaa O, Merterinne K, et al. Raised plasma endothelin-1 concentration following cold pressor test. Eur J Clin Invest. 1990;169:217-221.
37. Emre M, Orgul S, Haufschild T, et al. Increased plasma endothelin-1 levels in patients with progressive open angle glaucoma. Br J Ophthalmol. 2005;89:60-63.
38. Cardillo C, Kilcoyne CM, Cannon RO 3rd, et al. Interactions between nitric oxide and endothelin in the regulation of vascular tone of human resistance vessels in vivo. Hypertension. 2000;35:1237-1241.
39. Newby DE, Strachan FE, Webb DJ. Abnormal endothelin B receptor vasomotor responses in patients with Hirschsprung's disease. QJM. 2002;95:159-163.
40. Chakravarthy U, Douglas AJ, Bailie JR, et al. Immunoreactive endothelin distribution in ocular tissues. Invest Ophthalmol Vis Sci. 1994;35:2448-2454.
41. Haefliger IO, Flammer J, Luscher TF. Nitric oxide and endothelin-1 are important regulators of human ophthalmic artery. Invest Ophthalmol Vis Sci. 1992;33:2340-2343.
42. MacCumber MW, D'Anna SA. Endothelin receptor-binding subtypes in the human retina and choroid. Ophthalmology. 1994;112:1231-1235.
43. Meyer P, Flammer J, Luscher TF. Endothelium-dependent regulation of the ophthalmic microcirculation in the perfused porcine eye: role of nitric oxide and endothelins. Invest Ophthalmol Vis Sci. 1993;34:3614-3621.
44. Neufeld AH, Hernandez MR, Gonzalez M. Nitric oxide synthase in the human glaucomatous optic nerve head. Arch Ophthalmol. 1997;115:497-503.
45. Stitt AW, Chakravarthy U, Gardiner TA, et al. Endothelin-like immunoreactivity and receptor binding in the choroid and retina. Curr Eye Res. 1995;15:111-117.
46. Wollensak G, Schaefer HE, Ihling C. An immunohistochemical study of endothelin-1 in the human eye. Curr Eye Res. 1998;17:541-545.
47. Becquet F, Courtois Y, Goureau O. Nitric oxide in the eye: multi-faceted roles and diverse outcomes. Surv Ophthalmol. 1997;42:71-82.
48. Haefliger IO, Meyer P, Flammer J, et al. The vascular endothelium as a regulator of the ocular circulation: a new concept in ophthalmology? Surv Ophthalmol. 1994;39:123-132.
49. Haefliger IO, Anderson DR. Blood flow regulation in the optic nerve head. In: Ritch R, Shields MB, Krupin T, eds. The Glaucomas: Basic Sciences. Vol. 1. 2nd ed. St Louis: Mosby; 1996:189-197.
50. Luksch A, Polak K, Beier C, et al. Effects of systemic NO synthase inhibition on choroidal and optic nerve head blood flow in healthy subjects. Invest Ophthalmol Vis Sci. 2000;41:3080-3084.
51. Okuna T, Oku H, Sugiyama T, et al. Evidence that nitric oxide is involved in autoregulation in optic nerve head of rabbits. Invest Ophthalmol Vis Sci. 2002;43:784-789.
52. Schmetterer L, Krejcy K, Kastner J, et al. The effect of systemic nitric oxide-synthase inhibition on ocular fundus pulsations in man. Exp Eye Res. 1997;64:305-312.
53. Schmetterer L, Polak K. Role of nitric oxide in the control of ocular blood flow. Prog Ret Eye Res. 2001;20:823-847.
54. Chauhan BC, LeVatte TL, Jollimore CA, et al. Model of endothelin-1-induced chronic optic neuropathy in rat. Invest Ophthalmol Vis Sci. 2004;45:144-152.
55. Oku H, Sugiyama T, Kojima S, et al. Experimental optic cup enlargement caused by endothelin-1-induced chronic optic nerve head ischemia. Surv Ophthalmol. 1999;44:S74 -S84.
56. Orgul S, Cioffi GA, Bacon DR, et al. An endothelin-1 induced model of chronic optic nerve ischemia in the rabbit. Invest Ophthalmol Vis Sci. 1996;37:1860-1869.
57. Galassi F, Sodi A, Ucci F, et al. Ocular haemodynamics and nitric oxide in normal pressure glaucoma. Acta Ophthalmol Scand Suppl. 2000;232:37-38.
58. Yang ZH, Richard V, von Segesser L, et al. Threshold concentrations of endothelin-1 potentiate contractions to norepinephrine and serotonin in human arteries: a new mechanism of vasospasm? Circulation. 1990;82:188-195.