The endothelin system in cardiovascular physiology and pathophysiology

Vascular Medicine

Volumn 2, Issue 1, 1997, Pages 31-43

  Parris, Richard J ^a   Webb, David J ^a  

^a UNIVERSITY OF EDINBURGH   (United Kingdom)

Author keywords

Cardiovascular disease; Endothelin antagonists; Endothelin 1; Endothelium; Human vasoconstriction

Indexed keywords

BOSENTAN; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); DEOXYCORTICOSTERONE ACETATE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENDOTHELIN 1; ENDOTHELIN 2; ENDOTHELIN 3; ENDOTHELIN A RECEPTOR; ENDOTHELIN B RECEPTOR; ENDOTHELIN RECEPTOR; ENDOTHELIN RECEPTOR ANTAGONIST; HYPERTENSIVE FACTOR; N (2,6 DIMETHYLPIPERIDINOCARBONYL) 4 METHYLLEUCYL DEXTRO (1 METHOXYCARBONYLTRYPTOPHANYL) DEXTRO NORLEUCINE; NITRIC OXIDE; SARAFOTOXIN S6C; TAK 044; VASOCONSTRICTOR AGENT; CARVEDILOL; CYCLIC AMP; ENDOTHELIN CONVERTING ENZYME; HYDRALAZINE; N(G) NITROARGININE METHYL ESTER; NATRIURETIC PEPTIDE TYPE C; NITRIC ACID DERIVATIVE; PHOSPHORAMIDON; PREPROENDOTHELIN 1; THROMBOXANE A2; TRANSFORMING GROWTH FACTOR BETA;

ARTICLE; ATHEROSCLEROSIS; BLOOD PRESSURE; BLOOD VESSEL TONE; BRAIN CIRCULATION; CARDIOVASCULAR DISEASE; CLINICAL TRIAL; CORONARY ARTERY BLOOD FLOW; FETUS DEVELOPMENT; HEART FAILURE; HUMAN; INTRAVENOUS DRUG ADMINISTRATION; ISCHEMIC HEART DISEASE; KIDNEY CIRCULATION; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; PULMONARY HYPERTENSION; SUBARACHNOID HEMORRHAGE; VASOCONSTRICTION; VASOSPASM; AMINO ACID SEQUENCE; BLOOD PRESSURE MEASUREMENT; BRAIN ISCHEMIA; CARDIOVASCULAR FUNCTION; CONGESTIVE HEART FAILURE; DEVELOPMENTAL BIOLOGY; DIABETES MELLITUS; DNA FLANKING REGION; GOLGI COMPLEX; HYPERTENSION; KIDNEY FAILURE; MIGRAINE; MOLECULAR BIOLOGY; PATHOPHYSIOLOGY; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; PULMONARY VASCULITIS; RAYNAUD PHENOMENON; TRANSLUMINAL CORONARY ANGIOPLASTY; VARIANT ANGINA PECTORIS;

EID: 0030792037     PISSN: 1358863X     EISSN: None     Source Type: Journal    
DOI: 10.1177/1358863X9700200106     Document Type: Article

References (18)

1. Yanagisawa M, Kurihara H, Kimura S et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988; 332: 411-15.
2. Inoue A, Yanagisawa M, Kimura S. The human endothelin family: three structurally and pharmacologically distinct isopeptides predicted by three separate genes. Proc Natl Acad Sci USA 1989; 86: 2863-67.
3. Kimura S, Kasuya Y, Sawamura T. Structure-activity relationships of endothelin: importance of the C-terminal moiety. Biochem Biophys Res Commun 1988; 156: 1182-86.
4. Randall MD, Douglas SA, Hiley CR. Vascular activities of endothelin-1 and some alanyl substituted analogues in resistance beds of the rat. Br J Pharmacol 1989; 98: 685-99.
5. MacArthur H, Warner TD, Wood EG, Corder R, Vane JR. Endothelin-1 release from endothelial cells in culture is elevated both acutely and chronically by short periods of mechanical stretch. Biochem Biophys Res Commun 1994; 200: 396-400.
6. McClellan G, Weisberg A, Rose D, Winegrad S. Endothelial cell storage and release of endothelin as a cardioregulatory mechanism. Circ Res 1994; 75: 85-96.
7. Emori T, Hirat Y, Ohta K. Cellular mechanisms of endothelin-1 release by angiotensin and vasopressin. Hypertension 1991; 18: 165-70.
8. Marsden PA, Dorfman DM, Collins T, Brenner BM, Orkin SH, Ballermann BJ. Regulated expression of endothelin-1 in glomerular capillary endothelial cells. Am J Physiol 1991; 261: F117-25.
9. Hu RM, Levin ER, Pedram A, Frank HJ. Insulin stimulates production and secretion of endothelin from bovine endothelial cells. Diabetes 1993; 42: 351-58.
10. Yokokawa K, Kohno M, Yasunari K, Murakawa K, Takeda T. Endothelin-3 regulates endothelin-1 production in cultured human endothelial cells. Hypertension 1991; 18: 304-15.
11. Yoshizumi M, Kurihara H, Morita T. Interleukin-1 increases the production of endothelin-1 by cultured endothelial cells. Biochem Biophys Res Commun 1990; 166: 342-29.
12. Kurihara H, Yoshizumi M, Sugiyama T. Transforming growth factor-beta stimulates the expression of endothelin mRNA by vascular endothelial cells. Biochem Biophys Res Commun 1989; 159: 1435-40.
13. Sugiura M, Inagami T, Kon V. Endotoxin stimulates endothelin release in vivo and in vitro as determined by radioimmunoassay. Biochem Biophys Res Commun 1989; 161: 1220-27.
14. Matin-Nizard F, Houssaini HS, Lestavel-Delattre S, Duriez P, Fruehart JC. Modified low density lipoproteins activate macrophages to secrete ir-ET. FEBS Lett 1991; 293: 127-30.
15. Milner P, Bodin P, Loesch A, Burnstock G. Rapid release of endothelin and ATP from isolated aortic endothelial cells exposed to increased flow. Biochem Biophys Res Commun 1990; 170: 649-56.
16. Kourembanas S, Marsden PA, McQuillan LP, Faller DV. Hypoxia induces endothelin gene expression and secretion in cultured human endothelium. J Clin Invest 1991; 88: 1054-57.
17. Gray GA, Webb DJ. The molecular biology and pharmacology of the endothelins. Molecular Biology Intelligence Unit Monograph Series. Austin, TX: RG Landes Co., 1995: 173.
18. Inoue A, Yanagisawa M, Takuwa Y, Mitsui Y, Kobayashi M, Masaki T. The preproendothelin-1 gene: complete nucleotide sequence and regulation of expression. J Biol Chem 1989; 264: 14954-59.