Two novel proteins bind specifically to trichosanthin on choriocarcinoma cell membrane

Journal of Biochemistry

Volumn 139, Issue 4, 2006, Pages 725-731

  Xia, Xuechun ^a   Hou, Fajian ^b   Li, Jie ^a   Ke, Yibao ^a   Nie, Huiling ^a  

^a INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Cell surface biotinylation; Choriocarcinoma cells; Cytotoxicity; Radioligand binding assay; Trichosanthin

Indexed keywords

CALCIUM; CHEMOKINE RECEPTOR CCR5; TRICHOSANTHIN;

ANIMAL CELL; ARTICLE; BINDING ASSAY; BINDING SITE; BIOTINYLATION; CALCIUM TRANSPORT; CARCINOMA CELL; CELL MEMBRANE; CHORIOCARCINOMA; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG INHIBITION; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; MOLECULAR WEIGHT; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING; PROTEIN ISOLATION; RADIOASSAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BIOTINYLATION; CALCIUM; CARRIER PROTEINS; CELL LINE; CELL LINE, TUMOR; CELL MEMBRANE; CELL SURVIVAL; CHORIOCARCINOMA; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; FEMALE; HUMANS; IMMUNOBLOTTING; MICROSCOPY, CONFOCAL; PLANT PROTEINS; PROTEIN BINDING; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TRICHOSANTHIN; UTERINE NEOPLASMS;

TRICHOSANTHES;

EID: 33745654303     PISSN: 0021924X     EISSN: None     Source Type: Journal    
DOI: 10.1093/jb/mvj081     Document Type: Article

References (37)

1. Zhang, X.J. and Wang, J.H. (1986) Homology of trichosanthin and ricin A chain. Nature 321, 477-478
2. Zhang, J.S. and Liu, W.Y. (1992) The mechanism of action of trichosanthin on eukaryotic ribosomes-RNA N-glycosidase activity of the cytotoxin. Nucleic. Acids. Res. 20, 1271-1275
3. Jin, S.W., Sun, X.X., Wang, S.F., Tian, G.Y., Gu, Z.W., Qian, W.W., Liu, Y.Z., She, W.Y., Qian, R.Q., and Wang, Y. (1981) Physical and chemical properties of crystalline trichosanthin. Acta Chim. Sin. 39, 917-926
4. Wang, Y., Qian, R.Q., Gu, Z.W., Jin, S.W., Zhang, L.Q., Xia, Z.X., Tian, G.Y., and Ni, C.Z. (1986) Scientific evaluation of Tian Hua Fen(THF)-history, chemistry and application. Pure Appl. Chem. 58, 789-798
5. Lu, P.X. and Jin, Y.C. (1990) Trichosanthin in the treatment of hydatidiform mole: clinical analysis of 52 cases. Chin. Med. J. 103, 183-185
6. Tsao, S.W., Yan, K.T., and Yeung, H.W. (1986) Selective killing of choriocarcinoma cells in vitro by trichosanthin, a plant protein purified from root tubers of the Chinese medicinal herb Trichosanthes kirilowii. Toxicon 24, 831-840
7. Chow, T.P., Feldman, R.A., Lovett, M., and Piatak, M. (1990) Isolation and DNA sequence of a gene encoding alpha-trichosanthin, a type I ribosome-inactivating protein. J. Biol. Chem. 265, 8670-8674
8. Shaw, P.C., Chan, W.L., Yeung, H.W., and Ng, T.B. (1994) Minireview: trichosanthin-a protein with multiple pharmacological properties. Life Sci. 55, 253-262
9. McGrath, M.S., Hwang, KM., Caldwell, S.E., Gaston, I., Luk, K.C., Wu, P. Ng, V.L., Crowe, S., Daniels, J., and Marsh, J. (1989) GLQ223: an inhibitor of human immunodeficiency virus replication in acutely and chronically infected cells of lymphocyte and mononuclear phagocyte lineage. Proc. Natl. Acad. Sci. USA 86, 2844-2848
10. McGrath, M.S., Santulli, S., and Gaston, I. (1990) Effects of GLQ223 on HIV replication in human monocyte/macrophages chronically infected in vitro with HIV. AIDS Res. Hum. Retroviruses 6, 1039-1043
11. Liu, G.W., Liu, F.Y., Liu, Y.J., and Yu, S.H. (1985) A summary of 402 cases of termination early pregnancy with crystalline preparation of trichosanthin in Advances in Chinese Medicinal Material Research (Chang, H.M., Yeung, H.W., Tso, W.W., and Koo, A., eds.) pp. 327-329, World Scientific Publ., Singapore
12. Wang, Y., Ju, R., Huang, J., and Hsu, K. (1976) Investigations on the injurious effects of the abortifacient trichosanthin to monkey placental villi. Acta Zool. Sin. 22, 156-158
13. Wang, Y.T., Hsu, K.C., and Chiang, W.S. (1978) The ultrastructural observations on the injurious effects of the abortifacient trichosanthin on monkey trophoblast. Acta Biol. Exp. Sin. 11, 263-265
14. Xiong, Y.Z., Pan, P., Xu, S.Y., Zhang, J., Wang, Y.H., Zuo, J., and Gu, Z. (1976) Study on the effects of trichosanthin on human trophoblast cells in vitro. Acta Zool. Sin. 22, 172-175
15. Lu, Y., Xia, X., and Sui, S. (2001) The interaction of trichosanthin with supported phospholipid membranes studied by surface plasmon resonance. Biochim. Biophys. Acta 1512, 308-316
16. Chan, W.L., Shaw, P.C., Tam, S.C., Jacobsen, C., Gliemann, J., and Nielsen, M.S. (2000) Trichosanthin interacts with and enters cells via LDL receptor family members. Biochem. Biophys. Res. Commun. 270, 453-457
17. Zhao, J., Ben, L.H., Wu, Y.L., Hu, W., Ling, K., Xin, S.M., Nie, H.L., Ma, L., and Pei, G. (1999) Anti-HIV agent trichosanthin enhances the capabilities of chemokines to stimulate chemotaxis and G protein activation, and this is mediated through interaction of trichosanthin and chemokine receptors. J. Exp. Med. 190, 101-111
18. Zhang, C., Gong, Y., Ma, H., An, C., Chen, D., and Chen, Z.L. (2001) Reactive oxygen species involved in trichosanthin-induced apoptosis of human choriocarcinoma cells. Biochem. J. 355, 653-661
19. Mosmann, T. (1983) Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J. Immunol. Methods 65, 55-63
20. Yamagishi, S., Yamada, M., Koshimizu, H., Takai, S., Hatanaka, H., Takeda, K., Ichijo, H., Shimoke, K., and Ikeuchi, T. (2003) Apoptosis-signal regulating kinase-1 is involved in the low potassium-induced activation of p38 mitogen-activated protein kinase and c-Jun in cultured cerebellar granule neurons. J Biochem. 133, 719-724.
21. Radsak, M.P., Hilf, N., Singh-Jasuja, H., Braedel, S., Brossart, P., Rammensee, H.G., and Schild, H. (2003) The heat shock protein Gp96 binds to human neutrophils and monocytes and stimulates effector functions. Blood 101, 2810-2815
22. Ma, Y.Q. and Geng, J.G. (2002) Obligatory requirement of sulfation for P-selectin binding to human salivary gland carcinoma Acc-M cells and breast carcinoma ZR-75-30 cells. J. Immunol. 168, 1690-1696
23. Ke, Y.B., Chen, J.K., Nie, H.L., He, X.H., Ke, X.Y., and Wang, Y.H. (1997) Structure-function relationship of trichosanthin. Life Sci. 60, 465-472
24. Yoshimura, T. and Leonard, E.J. (1990) Identification of high affinity receptors for human monocyte chemoattractant protein-1 on human monocytes. J. Immunol. 145, 292-297
25. Cox, D. and Seki, J. (1998) Characterization of the binding of FK633 to the platelet fibrinogen receptor. Thromb. Res. 91, 129-136
26. 125iodocyanopindolol binding to beta-adrenoceptors on human lymphocytes: evidence for the existence of two classes of binding sites. J. Recept. Res. 8, 47-57
27. Ding, X.Z., Smallridge, R.C., Galloway, R.J., and Kiang, J.G. (1996) Rapid assay of HSF1 and HSF2 gene expression by RT-PCR. Mol. Cell. Biochem. 158, 189-192
28. Douglas, G.G., Thirkill, T.L., Sideris, V., Rabieh, M., Trollinger, D., and Nuccitelli, R. (2001) Chemokine receptor expression by human syncytiotrophoblast. J. Reprod. Immunol. 49, 97-114
29. Meier, T., Arni, S., Malarkannan, S., Poincelet, M., and Hoessli, D. (1992) Immunodetection of biotinylated lymphocyte-surface proteins by enhanced chemiluminescence: a nonradioactive method for cell-surface protein analysis. Anal. Biochem. 204, 220-226
30. Altin, J.G. and Pagler, E.B. (1995) A one-step procedure for biotinylation and chemical cross-linking of lymphocyte surface and intracellular membrane-associated molecules. Anal. Biochem. 224, 382-389
31. Gunther, G.R., Wang, J.L., Yahara, I., Cunningham, B.A., and Edelman, G.M. (1973) Concanavalin A derivatives with altered biological activities. Proc Natl. Acad. Sci. USA 70, 1012-1016
32. Mogi, K., Takeshita, H., Yasuda, T., Nakajima, T., Nakazato, E., Kaneko, Y., Itoi, M., and Kishi, K. (2003) Carp hepatopancreatic DNase I: biochemical, molecular, and immunological properties. J. Biochem. 133, 377-386
33. Suzuki, S., Miyagi, T., Chuang, L.F., Yau, P.M., Doi, R.H., and Chuang, R.Y. (2002) Chemokine receptor CCR5: polymorphism at protein level. Biochem. Biophys. Res. Commun. 296, 477-483
34. Lee, B., Sharron, M., Blanpain, C., Doranz, B.J., Vakili, J., Setoh, P., Berg, E., Liu, G., Guy, H.R., Durell, S.R., Parmentier, M., Chang, C.N., Price, K., Tsang, M., and Doms, R.W. (1999) Epitope mapping of CCR5 reveals multiple conformational states and distinct but overlapping structures involved in chemokine and coreceptor function. J. Biol. Chem. 274, 9617-9626
35. Wang, J.H., Nie, H.L., Huang, H., Tam, S.C., and Zheng, Y.T. (2003) Independency of anti-HIV-1 activity from ribosome-inactivating activity of trichosanthin. Biochem. Biophys. Res. Commun. 302, 89-94
36. Nie, H.L., Cai, X., He, X., Xu, L., Ke, X., Ke, Y., and Tam, S.C. (1998) Position 120-123, a potential active site of trichosanthin. Life Sci. 62, 491-500
37. Wu, Z.H., Nie, H.L., Lu, B., Wang, Q., and Ke, Y.B. (1999) Activation of G protein on the membrane of TCS-sensitive cells. Acta Biol. Exp. Sin. 32, 151-156