Detection of HBsAg mutants

Journal of Medical Virology

Volumn 78, Issue SUPPL. 1, 2006, Pages

  Osiowy, Carla ^a,b  

^a PUBLIC HEALTH AGENCY OF CANADA   (Canada)

^b Public Health Agency of Canada   (Canada)

Author keywords

Detection assays; HBsAg mutants

Indexed keywords

EPITOPE; HEPATITIS B SURFACE ANTIGEN; NUCLEIC ACID;

ANALYTIC METHOD; ANTIGEN DETECTION; GAP LIGASE CHAIN REACTION; GENETIC POLYMORPHISM; GENOTYPE; HEPATITIS B; HEPATITIS B VIRUS; HUMAN; IMMUNOASSAY; LIMITING DILUTION CLONING POLYMERASE CHAIN REACTION; NONHUMAN; NUCLEOTIDE SEQUENCE; POINT MUTATION; POLYMERASE CHAIN REACTION; REAL TIME POLYMERASE CHAIN REACTION; REVIEW; SENSITIVITY AND SPECIFICITY; SEQUENCE ANALYSIS; VIRUS DETECTION; VIRUS MUTANT;

ANTIGENIC VARIATION; DNA, VIRAL; GENES, VIRAL; HEPATITIS B; HEPATITIS B ANTIBODIES; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HUMANS; MUTATION; NUCLEIC ACID AMPLIFICATION TECHNIQUES; SENSITIVITY AND SPECIFICITY; VIREMIA;

HEPATITIS B VIRUS;

EID: 33745631241     PISSN: 01466615     EISSN: 10969071     Source Type: Journal    
DOI: 10.1002/jmv.20607     Document Type: Review

References (20)

1. Hu H, Peng X, Huang Y, Gu L, Xie Q, Gao Z. 2004. Yeast expression and DNA immunization of hepatitis B virus S gene with second-loop deletion of a determinant region. World J Gastroenterol 10:2989-2993.
2. Hu W, Wei J, Xia H, Yang X, Li F, Li G, Wang Y, Zhang Z. 2005. Identification of the immunogenic domains in HBsAg preS1 region using overlapping preS1 fragment fusion proteins. World J Gastroenterol 11:2088-2094.
3. Ijaz S, Ferns RB, Tedder RS. 2003. A "first loop" linear epitope accessible on native hepatitis B surface antigen that persists in the face of "second loop" immune escape. J Gen Virol 84:269-275.
4. Jeantet D, Chemin I, Mandrand B, Tran A, Zoulim F, Merle P, Trepo C, Kay A. 2004. Cloning and expression of surface antigens from occult chronic hepatitis B virus infections and their recognition by commercial detection assays. J Med Virol 73:508-515.
5. Kalinina T, Iwanski A, Will H, Sterneck M. 2003. Deficiency in virion secretion and decreased stability of the hepatitis B virus immune escape mutant G145R. Hepatology 38:1274-1281.
6. Khan N, Guarnieri M, Ahn SH, Li J, Zhou Y, Bang G, Kim K, Wands JR, Tong S. 2004. Modulation of hepatitis B virus secretion by naturally occurring mutations in the S gene. J Virol 78:3262-3270.
7. Levicnik-Stezinar S. 2004. Hepatitis B surface antigen escape mutant in a first time blood donor potentially missed by a routine screening assay. Clin Lab 50:49-51.
8. Louisirirotchanakul S, Kanoksinsombat C, Theamboonlert A, Puthavatana P, Wasi C, Poovorawan Y. 2004. Mutation of the "a" determinant of HBsAg with discordant HBsAg diagnostic kits. Viral Immunol 17:440-444.
9. Moerman B, Moons V, Sommer H, Schmitt Y, Stetter M. 2004. Evaluation of sensitivity for wild type and mutant forms of hepatitis B surface antigen by four commercial HBsAg assays. Clin Lab 50:159-162.
10. Nainan OV, Khristova ML, Byun K, Xia G, Taylor PE, Stevens CE, Margolis HS. 2002. Genetic variation of hepatitis B surface antigen coding region among infants with chronic hepatitis B virus infection. J Med Virol 68:319-327.
11. Osiowy C. 2002. Sensitive detection of HBsAg mutants by a gap-ligase chain reaction assay. J Clin Micro 40:2566-2571.
12. Paulij WP, deWit PLM, Sunnen CMG, van Roosmalen MH, Petersen-van Ettekoven A, Cooreman MP, Heijtink RA. 1999. Localization of a unique hepatitis B virus epitope sheds new light on the structure of hepatitis B virus surface antigen. J Gen Virol 80:2121-2126.
13. Roohi A, Khoshnoodi J, Zarnani AH, Shokri F. 2005. Epitope mapping of recombinant hepatitis B surface antigen by murine monoclonal antibodies. Hybridoma 24:71-77.
14. Thakur V, Kazim SN, Guptan RC, Hasnain SE, Bartholomeusz A, Malhotra V, Sarin SK. 2005. Transmission of G145R mutant of HBV to an unrelated contact. J Med Virol 76:40-46.
15. Torresi J, Earnest-Silveira L, Deliyannis G, Edgtton K, Zhuang H, Locarnini SA, Fyfe J, Sozzi T, Jackson DC. 2002. Reduced antigenicity of the hepatitis B virus HBsAg protein arising as a consequence of sequence changes in the overlapping polymerase gene that are selected by lamivudine therapy. Virology 293:305-313.
16. Wagner AA, Denis F, Weinbreck P, Loustaud V, Autofage F, Rogez S, Alain S. 2004. Serological pattern "anti-hepatitis B core alone" in HIV or hepatitis C virus-infected patients is not fully explained by hepatitis B surface antigen mutants. AIDS 18:569-571.
17. Weber B. 2005. Genetic variability of the S gene of hepatitis B virus: Clinical and diagnostic impact. J Clin Virol 32:102-112.
18. Weber B, Muhlbacher A, Melchior W. 2005. Detection of an acute asymptomatic HBsAg negative hepatitis B virus infection in a blood donor by HBV DNA testing. J Clin Virol 32:67-70.
19. Zhang M, Gong Y, Osiowy C, Minuk GY. 2002. Rapid detection of hepatitis B virus mutations using real-time PCR and melting curve analysis. Hepatology 36:723-728.
20. Zheng X, Weinberger KM, Gehrke R, Isogawa M, Hilken G, Kemper T, Xu Y, Yang D, Jilg W, Roggendorf M, Lu M. 2004. Mutant hepatitis B virus surface antigens (HBsAg) are immunogenic but may have a changed specificity. Virology 329:454-464.