Localization of a unique hepatitis B virus epitope sheds new light on the structure of hepatitis B virus surface antigen

Journal of General Virology

Volumn 80, Issue 8, 1999, Pages 2121-2126

  Paulij, W P ^a   De Wit, P L M ^a   Sunnen C M G ^a   Van Roosmalen, M H ^a   Petersen Van Ettekoven, A ^a   Cooreman, M P ^c   Heijtink, R A ^b  

^a Organon Teknika   (Netherlands)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; EPITOPE; HEPATITIS B SURFACE ANTIBODY; HEPATITIS B SURFACE ANTIGEN; MONOCLONAL ANTIBODY;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL EXPERIMENT; ANTIBODY RESPONSE; ANTIGEN RECOGNITION; ARTICLE; HEPATITIS B VIRUS; NONHUMAN; PRIORITY JOURNAL; RABBIT; VIRUS IMMUNITY; VIRUS PARTICLE;

ANIMALIA; DNA VIRUSES; HEPATITIS B VIRUS; ORYCTOLAGUS CUNICULUS;

EID: 0032809591     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/0022-1317-80-8-2121     Document Type: Article

References (29)

1. Ashton-Rickardt, P. G. & Murray, K. (1989). Mutations that change the immunological subtype of hepatitis B virus surface antigen and distinguish between antigenic and immunogenic determination. Journal of Medical Virology 29, 204-214.
2. Berting, A., Hahnen, J., Kröger, M. & Gerlich, W. H. (1995). Computer-aided studies on the spatial structure of the small hepatitis B surface protein. Intervirology 38, 8-15.
3. Carman, W. F. (1997). The clinical significance of surface antigen variants of hepatitis B virus. Journal of Viral Hepatitis 4 (Suppl. 1), 11-20.
4. Carman, W. F., Zanetti, A. R., Karayiannis, P., Waters, J., Manzillo, G., Tanzi, E., Zuckerman, A. J. & Thomas, H. C. (1990). Vaccine-induced escape mutant of hepatitis B virus. Lancet 336, 325-329.
5. Carman, W. F., Korula, J., Wallace, L., MacPhee, R., Mimms, L. & Decker, R. (1995). Fulminant reactivation of hepatitis B due to envelope protein mutant of HBV that escaped detection by monoclonal HBsAg ELISA. Lancet 345, 1406-1407.
6. Carman, W. F., Van Deursen, F. J., Mimms, L. T., Hardie, D., Coppola, R., Decker, R. & Sanders, R. (1997). The prevalence of surface antigen variants of hepatitis B virus in Papua New Guinea, South Africa and Sardinia. Hepatology 26, 1658-1666.
7. Chen, Y. C. J., Delbrook, K., Dealwis, C., Mimms, L., Mushahwar, I. K. & Mandecki, W. (1996). Discontinuous epitopes of hepatitis B surface antigen from a filamentous phage peptide library. Proceedings of the National Academy of Sciences, USA 93, 1997-2001.
8. Fujiyama, A., Miyanohara, A., Nozaki, C., Yoneyama, T., Ohtomo, N. & Matsubaru, K. (1983). Cloning and structural analysis of hepatitis B virus DNAs, subtype adr. Nucleic Acid Research 11, 4601-4610.
9. Gerlich, W. H., Lu, X. & Heermann, K. H. (1993). Studies on the attachment and penetration of hepatitis B virus. Journal of Hepatology 17 (Suppl. 3), S10-S14.
10. Geysen, H. M., Meloen, R. H. & Tainer, J. A. (1986). Protein Engineering; Application in Science, Industry and Medicine, pp. 41-69. Edited by M. Inouye. New York: Academic Press.
11. Grethe, S., Monazahian, M., Böhme, I. & Thomsson, R. (1998). Characterization of unusual escape variants of hepatitis B virus isolated from a hepatitis B surface antigen-negative subject. Journal of Virology 72, 7692-7696.
12. Guerrero, E., Gavilanes, F. & Peterson, D. L. (1988). Model for the protein arrangement in HBsAg particles based on physical and chemical studies. In Viral Hepatitis & Liver Disease, pp. 606-613. Edited by A. J. Zuckerman. New York: Liss.
13. Heijtink, R. A., Kruining, J., Weber, Y. A. M., de Man, R. A. & Schalm, S. W. (1995). Anti-hepatitis B virus activity of a mixture of two monoclonal antibodies in an 'inhibition in solution' assay. Hepatology 22, 1078-1083.
14. Hertogs, K., Leenders, W. P., Depla, E., De Bruin, W. C., Meheus, L., Raymackers, J., Moshage, H. & Yap, S. H. (1993). Endonexin II, present on human liver plasma membranes, is a specific binding protein of the small hepatitis B (HBV) envelope protein. Virology 197, 549-557.
15. Hertogs, K., Depla, E., Crabbe, T., De Bruin, W. C. C., Leenders, W. P., Moshage, H. & Yap, S. H. (1994). Spontaneous development of anti-hepatitis B virus (anti-idiotypic) antibodies in animals immunised with human liver endonexin II or with the F(ab')2 fragment of anti-human liver endonexin II immunoglobulin G: evidence for a receptor-ligand-like relationship between small hepatitis B surface antigen and endonexin II. Journal of Virology 68, 1516-1521.
16. Howard, C. R., Stirk, H. J., Brown, S. E. & Steward, M. W. (1988). Towards the development of synthetic hepatitis B vaccines. In Viral Hepatitis & Liver Disease, pp. 1094-1101. Edited by A. J. Zuckerman. New York: Liss.
17. Leenders, W. P. J., Glansbeek, H., De Bruin, W. C. C. & Yap, S. H. (1990). Binding of the major and large HBsAg to hepatocytes and liver plasma membranes: putative external and internal receptors for infection and secretion of hepatitis B virus. Hepatology 12, 141-147.
18. Loncarevic, I. F., Zentgraf, H. & Schröder, C. H. (1990). Sequence of a replication competent hepatitis B virus genome with a prX open reading frame. Nucleic Acid Research 18, 4940.
19. Loomans, E. E. M. G., Nijholt, L. J., Cremers, A. J. H. F., Paulij, W. P. & Schielen, W. J. G. (1997). Epitope mapping and serodiagnosis using Ata-and (Lys)7 peptides. Biochimica et Biophysica Acta 1379, 273-281.
20. Mangold, C. M. T., Unckell, P., Werr, M. & Streeck, R. E. (1997). Analysis of intermolecular disulfide bonds and free sulfhydryl groups in hepatitis B surface antigen particles. Archives of Virology 142, 2257-2267.
21. Mbayed, V. A., Lopez, J. L., Telenta, P. F. S., Palacios, G., Badia, I., Ferro, A., Galoppo, C. & Campos, R. (1998). Distribution of hepatitis B virus genotypes in two different pediatric populations from Argentina. Journal of Clinical Microbiology 36, 3362-3365.
22. Norder, H., Hammas, B., Lee, S.-D., Bile, K., Couroucé, A.-M., Mushahwar, I. K. & Magnius, L. O. (1993). Genetic relatedness of hepatitis B viral strains of diverse geographical origin and natural variations in the primary structure of the surface antigen. Journal of General Virology 74, 1341-1348.
23. Norder, H., Couroucé, A. M. & Magnius, L. O. (1994). Complete genomes, phylogenetic relatedness and structural proteins of six strains of the hepatitis B virus, four of which represent two new genotypes. Virology 198, 489-503.
24. Ohno, T., Mizokumi, M., Wakita, T. & Kakumu, S. (1993). Defective short variants of S-region in chronic HBV carriers. Nippon Rinsho 51, 297-303.
25. Okamoto, H., Omi, S., Wong, Y., Itoh, Y., Isuda, F., Tanaka, T., Akahane, Y., Miyakawa, Y. & Mayumi, M. (1989). The loss of subtype determinants in alleles d/y or w/r on hepatitis B surface antigen. Molecular Immunology 26, 197-205.
26. Peterson, D. L., Paul, D. A., Lam, J., Tribby, I. I. E. & Achord, D. T. (1984). Antigenic structure of hepatitis B virus surface antigen: identification of the 'd' subtype determinant by chemical modification and use of monoclonal antibodies. Journal of Immunology 132, 920-927.
27. Stirk, H. J., Thornton, J. M. & Howard, C. R. (1992). A topological model for hepatitis B surface antigen. Intervirology 33, 148-158.
28. Stricker, E. A. M., Tiebout, P. F., Lelie, P. N. & Zeijlemaker, W. P. (1985). A human monoclonal IgG1 lambda anti-hepatitis B surface antibody: production, properties and application. Scandinavian Journal of Immunology 22, 337-343.
29. Waters, J., Kennedy, M., Voet, P., Hauser, P., Petre, J., Carman, W. & Thomas, H. C. (1992). Loss of the common 'a' determinant of hepatitis B surface antigen by a vaccine induced escape mutant. Journal of Clinical Investigations 90, 2543-2547.