The animal pathogen-like type III secretion system is required for the intracellular survival of Burkholderia mallei within J774.2 macrophages

Infection and Immunity

Volumn 74, Issue 7, 2006, Pages 4349-4353

  Ribot, Wilson J ^a   Ulrich, Ricky L ^a  

^a UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN;

ACTIN POLYMERIZATION; ANIMAL CELL; ARTICLE; BURKHOLDERIA MALLEI; CELL SURVIVAL; CONTROLLED STUDY; GRAM NEGATIVE BACTERIUM; HORSE DISEASE; INTRACELLULAR TRANSPORT; MACROPHAGE; NONHUMAN; PHAGOSOME; PRIORITY JOURNAL; SPONTANEOUS MUTATION;

ANIMALS; BURKHOLDERIA MALLEI; CELL LINE; INTRACELLULAR FLUID; LYSOSOMAL-ASSOCIATED MEMBRANE PROTEIN 1; MACROPHAGES; MICE; MUTAGENESIS; MUTATION;

EID: 33745625670     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.01939-05     Document Type: Article

References (15)

1. Bellaire, B. H., R. M. Roop II, and J. A. Cardelli. 2005. Opsonized virulent Brucella abortus replicates within nonacidic, endoplasmic reticulum-negative, LAMP-1-positive phagosomes in human monocytes. Infect. Immun. 73:3702-3713.
2. Cornelis, G. R., and F. Van Gijsegem. 2000. Assembly and function of type III secretory systems. Annu. Rev. Microbiol. 54:735-774.
3. DeShazer, D., and D. Waag. 2004. Glanders: new insights into an old disease, p. 209-237. In L. Lindler, F. Lebeda, and G. W. Korch (ed.), Biological weapons defense: infectious diseases and counterbioterrorism. The Humana Press, Inc., Totowa, N.J.
4. DeShazer, D., D. M. Waag, D. L. Fritz, and D. E. Woods. 2001. Identification of a Burkholderia mallei polysaccharide gene cluster by subtractive hybridization and demonstration that the encoded capsule is an essential virulence determinant. Microb. Pathog. 30:253-269.
5. Galan, J. E. 2001. Salmonella interactions with host cells: type III secretion at work. Annu. Rev. Cell Dev. Biol. 17:53-86.
6. Hueck, C. J. 1998. Type III protein secretion systems in bacterial pathogens of animals and plants. Microbiol. Mol. Biol. Rev. 62:379-433.
7. Miller, W. R., L. Pannell, L. Cravitz, W. A. Tanner, and T. Rosebury. 1947. Studies on certain biological characteristics of Malleomyces mallei and Malleomyces pseudomallei. J. Bacteriol. 55:115-126.
8. Stevens, J. M., R. L. Ulrich, L. A. Taylor, M. W. Wood, D. Deshazer, M. P. Stevens, and E. E. Galyov. 2005. Actin-binding proteins from Burkholderia mallei and Burkholderia thailandensis can functionally compensate for the actin-based motility defect of a Burkholderia pseudomallei bimA mutant. J. Bacteriol. 187:7857-7862.
9. Stevens, M. P., A. Friebel, L. A. Taylor, M. W. Wood, P. J. Brown, W. D. Hardt, and E. E. Galyov. 2003. A Burkholderia pseudomallei type III secreted protein, BopE, facilitates bacterial invasion of epithelial cells and exhibits guanine nucleotide exchange factor activity. J. Bacteriol. 185:4992-4996.
10. Stevens, M. P., A. Haque, T. Atkins, J. Hill, M. W. Wood, A. Easton, M. Nelson, C. Underwood-Fowler, R. W. Titball, G. J. Bancroft, and E. E. Galyov. 2004. Attenuated virulence and protective efficacy of a Burkholderia pseudomallei bsa type III secretion mutant in murine models of melioidosis. Microbiology 150:2669-2676.
11. Stevens, M. P., M. W. Wood, L. A. Taylor, P. Monaghan, P. Hawes, P. W. Jones, T. S. Wallis, and E. E. Galyov. 2002. An Inv/Mxi-Spa-like type III protein secretion system in Burkholderia pseudomallei modulates intracellular behaviour of the pathogen. Mol. Microbiol. 46:649-659.
12. Suparak, S., W. Kespichayawattana, A. Haque, A. Easton, S. Damnin, G. Lertmemongkolchai, G. J. Bancroft, and S. Korbsrisate. 2005. Multinucleated giant cell formation and apoptosis in infected host cells is mediated by Burkholderia pseudomallei type III secretion protein BipB. J. Bacteriol. 187:6556-6560.
13. Ulrich, R. L., K. Amemiya, D. Waag, C. J. Roy, and D. DeShazer. 2005. Aerogenic vaccination with a Burkholderia mallei auxotroph protects against aerosol-initiated glanders in mice. Vaccine 23:1986-1992.
14. Ulrich, R. L., and D. DeShazer. 2004. Type III secretion: a virulence factor delivery system essential for the pathogenicity of Burkholderia mallei. Infect. Immun. 72:1150-1154.
15. Warawa, J., and D. E. Woods. 2005. Type III secretion system cluster 3 is required for maximal virulence of Burkholderia pseudomallei in a hamster infection model. FEMS Microbiol. Lett. 242:101-108.