Type III Secretion: A Virulence Factor Delivery System Essential for the Pathogenicity of Burkholderia mallei

Infection and Immunity

Volumn 72, Issue 2, 2004, Pages 1150-1154

  Ulrich, Ricky L ^a   DeShazer, David ^a  

^a UNITED STATES ARMY MEDICAL RESEARCH INSTITUTE OF INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENOMIC DNA; VIRULENCE FACTOR;

ANIMAL MODEL; ARTICLE; BACTERIAL VIRULENCE; BURKHOLDERIA; BURKHOLDERIA MALLEI; COLONY FORMING UNIT; GRAM NEGATIVE BACTERIUM; HORSE DISEASE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PATHOGENICITY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; STRAIN DIFFERENCE; SYRIAN HAMSTER;

ANIMALS; BURKHOLDERIA MALLEI; CRICETINAE; FEMALE; MESOCRICETUS; MICE; MICE, INBRED BALB C; VACCINATION; VIRULENCE FACTORS;

EID: 0842304717     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.72.2.1150-1154.2004     Document Type: Article

References (15)

1. Dennis, J. J., and G. J. Zylstra. 1998. Plasposons: modular self-cloning minitransposon derivatives for rapid genetic analysis of gram-negative bacterial genomes. Appl. Environ. Microbiol. 64:2710-2715.
2. DeShazer, D., and D. M. Waag. New insights into an old disease. In L. Lindler, F. Lebeda, and G. W. Korch (ed.), Biological weapons defense: principles and mechanisms for infectious diseases counter-bioterrorism. The Humana Press, Inc., Totowa, N.J., in press.
3. DeShazer, D., D. M. Waag, D. L. Fritz, and D. E. Woods. 2001. Identification of a Burkholderia mallei polysaccharide gene cluster by subtractive hybridization and demonstration that the encoded capsule is an essential virulence determinant. Microb. Pathog. 30:253-269.
4. Hueck, C. J. 1998. Type III protein secretion systems in bacterial pathogens of animals and plants. Microbiol. Mol. Biol. Rev. 62:379-433.
5. Jeddeloh, J. A., D. L. Fritz, D. M. Waag, J. M. Hartings, and G. P. Andrews. 2003. Biodefense-driven murine model of pneumonic melioidosis. Infect. Immun. 71:584-587.
6. Miller, W. R., L. Pannell, L. Cravitz, W. A. Tanner, and T. Rosebury. 1948. Studies on certain biological characteristics of Malleomyces mallei and Malleomyces pseudomallei. II. Virulence and infectivity for animals. J. Bacteriol. 55:127-135.
7. National Research Council. 1996. Guide for the care and use of laboratory animals. National Academy Press, Washington, D.C.
8. Parker, M. 1990. Glanders and melioidosis, p. 392-394. In M. T. Parker and L. H. Collier (ed.), Topley & Wilson's principles of bacteriology, virology and immunity, 8th ed. B.C. Decker, Philadelphia, Pa.
9. Rainbow, L., C. A. Hart, and C. Winstanley. 2002. Distribution of type III secretion gene clusters in Burkholderia pseudomallei, B. thailandensis and B. mallei. J. Med. Microbiol. 51:374-384.
10. Reed, L. J., and H. Muench. 1938. A simple method of estimating fifty percent endpoints. Am. J. Hyg. 27:493-497.
11. Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
12. Simon, R., U. Priefer, and A. Pühler. 1983. A broad host range mobilization system for in vivo genetic engineering: transposon mutagenesis in gram-negative bacteria. BioTechniques 1:784-791.
13. Stevens, M. P., M. W. Wood, L. A. Taylor, P. Monaghan, P. Haws, P. W. Jones, T. S. Wallis, and E. E. Galyov. 2002. An Inv/Mxi-Spa-like type III protein secretion system in Burkholderia pseudomallei modulates intracellular behaviour of the pathogen. Mol. Microbiol. 46:649-659.
14. Waag, D., T. Chulay, M. England, and J. Williams. 1995. Validation of an enzyme immunoassay for serodiagnosis of acute Q fever. Eur. J. Clin. Microbiol. Infect. Dis. 14:421-427.
15. - phenotypes. J. Clin. Microbiol. 38:883-885.