-
1
-
-
0034917323
-
Organising evidence on QT prolongation and occurrence of Torsades de Pointes with non-antiarrhythmic drugs: A call for consensus
-
De Ponti F, Poluzzi E, Montanaro N. Organising evidence on QT prolongation and occurrence of Torsades de Pointes with non-antiarrhythmic drugs: A call for consensus. Eur J Clin Pharmacol 2001;57:185-209.
-
(2001)
Eur J Clin Pharmacol
, vol.57
, pp. 185-209
-
-
De Ponti, F.1
Poluzzi, E.2
Montanaro, N.3
-
2
-
-
0027330319
-
Relations of QTc prolongation on the electrocardiogram to Torsades de Pointes: Definitions and mechanisms
-
Morganroth J. Relations of QTc prolongation on the electrocardiogram to Torsades de Pointes: Definitions and mechanisms. Am J Cardiol 1993;72:10B-13B.
-
(1993)
Am J Cardiol
, vol.72
-
-
Morganroth, J.1
-
3
-
-
0029065958
-
Case report: Reversible QT prolongation with torsades de pointes in a patient with pimozide intoxication
-
Krähenbühl S, Sauter B, Kupferschmidt H, et al. Case report: Reversible QT prolongation with torsades de pointes in a patient with pimozide intoxication. Am J Med Sci 1995;309:315-6.
-
(1995)
Am J Med Sci
, vol.309
, pp. 315-316
-
-
Krähenbühl, S.1
Sauter, B.2
Kupferschmidt, H.3
-
4
-
-
0034036880
-
Drug-induced torsades de pointes: From molecular biology to bedside
-
Tamargo J. Drug-induced torsades de pointes: From molecular biology to bedside. Jpn J Pharmacol 2000;83:1-19.
-
(2000)
Jpn J Pharmacol
, vol.83
, pp. 1-19
-
-
Tamargo, J.1
-
5
-
-
33747858275
-
The potential for QT prolongation and proarrhythmia by non-antiarrhythmic drugs
-
Antzelevitch C, Escande D, Lacerda A, et al. The potential for QT prolongation and proarrhythmia by non-antiarrhythmic drugs. Eur Heart J 2001;22(Suppl K):K2-K120.
-
(2001)
Eur Heart J
, vol.22
, Issue.SUPPL. K
-
-
Antzelevitch, C.1
Escande, D.2
Lacerda, A.3
-
6
-
-
0029002969
-
A mechanistic link between ian inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel
-
Sanguinetti MC, Jiang C, Curran ME. A mechanistic link between ian inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel. Cell 1995;81:299-307.
-
(1995)
Cell
, vol.81
, pp. 299-307
-
-
Sanguinetti, M.C.1
Jiang, C.2
Curran, M.E.3
-
7
-
-
0038628044
-
The human genome project and drug discovery in psychiatry: Identifying novel targets
-
Preskorn SH. The human genome project and drug discovery in psychiatry: Identifying novel targets. J Psych Prac 2001;7:133-40.
-
(2001)
J Psych Prac
, vol.7
, pp. 133-140
-
-
Preskorn, S.H.1
-
8
-
-
0038449866
-
The human genome project and modern drug development in psychiatry
-
Preskorn SH. The human genome project and modern drug development in psychiatry. J Psych Prac 2000;6:272-6.
-
(2000)
J Psych Prac
, vol.6
, pp. 272-276
-
-
Preskorn, S.H.1
-
9
-
-
0038110524
-
Antipsychotic drug development in the pre-human-genome era: A full circle
-
Preskorn SH. Antipsychotic drug development in the pre-human-genome era: A full circle. J Psych Prac 2001;7:209-13.
-
(2001)
J Psych Prac
, vol.7
, pp. 209-213
-
-
Preskorn, S.H.1
-
10
-
-
33747844157
-
Drug discovery in psychiatry: Drilling down on the target of interest
-
Preskorn SH. Drug discovery in psychiatry: Drilling down on the target of interest. J Psych Prac 2001;7:267-72.
-
(2001)
J Psych Prac
, vol.7
, pp. 267-272
-
-
Preskorn, S.H.1
-
11
-
-
0031730222
-
Prolongation of QT interval in isolated feline hearts by antipsychotic drugs
-
Drici M-D, Wang W, Liu X-K, et al. Prolongation of QT interval in isolated feline hearts by antipsychotic drugs. J Clin Psychopharm 1998;18:477-81.
-
(1998)
J Clin Psychopharm
, vol.18
, pp. 477-481
-
-
Drici, M.-D.1
Wang, W.2
Liu, X.-K.3
-
12
-
-
0033052403
-
Thioridazine lengthens repolarization of cardiac ventricular myocytes by blocking the delayed rectifier potassium current
-
Drolet B, Vincent F, Rail J, et al. Thioridazine lengthens repolarization of cardiac ventricular myocytes by blocking the delayed rectifier potassium current. J Pharm Exp Ther 1999;288:1261-8.
-
(1999)
J Pharm Exp Ther
, vol.288
, pp. 1261-1268
-
-
Drolet, B.1
Vincent, F.2
Rail, J.3
-
13
-
-
0016710656
-
Familial QT prolongation and risk of sudden death
-
Furberg C, Hornell H. Familial QT prolongation and risk of sudden death. Acta Paediatr Scand 1975;64:777-82.
-
(1975)
Acta Paediatr Scand
, vol.64
, pp. 777-782
-
-
Furberg, C.1
Hornell, H.2
-
14
-
-
0029947311
-
Drug interactions, cardiac toxicity, and terfenadine: From bench to clinic?
-
Flockhart DA. Drug interactions, cardiac toxicity, and terfenadine: From bench to clinic? J Clin Psychopharmacol 1996;16:101-3.
-
(1996)
J Clin Psychopharmacol
, vol.16
, pp. 101-103
-
-
Flockhart, D.A.1
-
15
-
-
0026671408
-
Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine with concomitant administration of erythromycin
-
Honig PK, Woosley RL, Zamani K, et al. Changes in the pharmacokinetics and electrocardiographic pharmacodynamics of terfenadine with concomitant administration of erythromycin. Clin Pharmacol Ther 1992;52:231-8.
-
(1992)
Clin Pharmacol Ther
, vol.52
, pp. 231-238
-
-
Honig, P.K.1
Woosley, R.L.2
Zamani, K.3
-
16
-
-
0029879317
-
Grapefruit juice alters the systemic bioavailability and cardiac repolarization of terfenadine in poor metabolizers of terfenadine
-
Honig PK, Wortham DC, Lazarev A, et al. Grapefruit juice alters the systemic bioavailability and cardiac repolarization of terfenadine in poor metabolizers of terfenadine. J Clin Pharmacol 1996;36:345-51.
-
(1996)
J Clin Pharmacol
, vol.36
, pp. 345-351
-
-
Honig, P.K.1
Wortham, D.C.2
Lazarev, A.3
-
17
-
-
0027468346
-
Terfenadine-ketoconazole interaction: Pharmacokinetic and electrocardiographic consequences
-
Honig PK, Wortham DC, Zamani K, et al. Terfenadine-ketoconazole interaction: Pharmacokinetic and electrocardiographic consequences. JAMA 1993;269:1513-8.
-
(1993)
JAMA
, vol.269
, pp. 1513-1518
-
-
Honig, P.K.1
Wortham, D.C.2
Zamani, K.3
-
18
-
-
0027768575
-
Itraconazole affects single-dose terfenadine pharmacokinetics and cardiac repolarization pharmacodynamics
-
Honig PK, Wortham DC, Hull R, et al. Itraconazole affects single-dose terfenadine pharmacokinetics and cardiac repolarization pharmacodynamics. J Clin Pharmacol 1993;33:1201-6.
-
(1993)
J Clin Pharmacol
, vol.33
, pp. 1201-1206
-
-
Honig, P.K.1
Wortham, D.C.2
Hull, R.3
-
19
-
-
0026049440
-
Torsades de pointes occurring in association with terfenadine use
-
Mathews DR. Torsades de pointes occurring in association with terfenadine use. JAMA 1991;266:2375-6.
-
(1991)
JAMA
, vol.266
, pp. 2375-2376
-
-
Mathews, D.R.1
-
20
-
-
0027168405
-
Oxidation of the antihistaminic drug terfenadine in human liver microsomes: Role of cytochrome P-450 3A(4) in N-dealkylation and C-hydroxylation
-
Yun CH, Okerholm RA, Guengerich FP. Oxidation of the antihistaminic drug terfenadine in human liver microsomes: Role of cytochrome P-450 3A(4) in N-dealkylation and C-hydroxylation. Drug Metab Dispos 1993;21:403-9.
-
(1993)
Drug Metab Dispos
, vol.21
, pp. 403-409
-
-
Yun, C.H.1
Okerholm, R.A.2
Guengerich, F.P.3
-
21
-
-
0030009690
-
Inhibition of terfenadine metabolism in vitro by azole antifungal agents and by selective serotonin reuptake inhibitor antidepressants: Relation to pharmacokinetic interactions in vivo
-
von Moltke LL, Greenblatt DJ, Duan SX, et al. Inhibition of terfenadine metabolism in vitro by azole antifungal agents and by selective serotonin reuptake inhibitor antidepressants: Relation to pharmacokinetic interactions in vivo. J Clin Psychopharmacol 1996;16:104-12.
-
(1996)
J Clin Psychopharmacol
, vol.16
, pp. 104-112
-
-
Von Moltke, L.L.1
Greenblatt, D.J.2
Duan, S.X.3
-
22
-
-
0032700543
-
Differentiation of intestinal and hepatic cytochrome P450 3A activity with use of midazolam as an in vivo probe: Effect of ketoconazole
-
Tsunoda SM, Velez RL, von Moltke LL, et al. Differentiation of intestinal and hepatic cytochrome P450 3A activity with use of midazolam as an in vivo probe: Effect of ketoconazole. Clin Pharmacol Ther 1999;66:461-71.
-
(1999)
Clin Pharmacol Ther
, vol.66
, pp. 461-471
-
-
Tsunoda, S.M.1
Velez, R.L.2
Von Moltke, L.L.3
-
23
-
-
0027474601
-
Mechanism of the cardiotoxic actions of terfenadine
-
Woosley RL, Chen Y, Freiman JP, et al. Mechanism of the cardiotoxic actions of terfenadine. JAMA 1993;269:1532-6.
-
(1993)
JAMA
, vol.269
, pp. 1532-1536
-
-
Woosley, R.L.1
Chen, Y.2
Freiman, J.P.3
-
24
-
-
0026049440
-
Torsades de pointes occurring in association with terfenadine use
-
Mathews DR. Torsades de pointes occurring in association with terfenadine use. JAMA 1991;266:2375-6.
-
(1991)
JAMA
, vol.266
, pp. 2375-2376
-
-
Mathews, D.R.1
-
25
-
-
0025222965
-
Torsades de pointes occurring in association with terfenadine use
-
Monahan BP, Ferguson CL, Killeavy ES, et al. Torsades de pointes occurring in association with terfenadine use. JAMA 1990;264:2788-90.
-
(1990)
JAMA
, vol.264
, pp. 2788-2790
-
-
Monahan, B.P.1
Ferguson, C.L.2
Killeavy, E.S.3
-
26
-
-
0027474601
-
Mechanism of the cardiotoxic actions of terfenadine
-
Woosley RL, Chen Y, Freiman JP, et al. Mechanism of the cardiotoxic actions of terfenadine. JAMA 1993;269:1532-6.
-
(1993)
JAMA
, vol.269
, pp. 1532-1536
-
-
Woosley, R.L.1
Chen, Y.2
Freiman, J.P.3
-
27
-
-
0026752150
-
Torsades de pointes after treatment with terfenadine and ketoconazole
-
Zimmerman M, Duruz H, Guinand O, et al. Torsades de pointes after treatment with terfenadine and ketoconazole. Eur Heart J 1992;13:1002-3.
-
(1992)
Eur Heart J
, vol.13
, pp. 1002-1003
-
-
Zimmerman, M.1
Duruz, H.2
Guinand, O.3
-
28
-
-
0029966447
-
Coprescription of terfenadine and erythromycin or ketaconazole: An assessment of potential harm: Pharmacists can be key in changing prescribing behavior to avoid drug-drug interactions
-
Carlson A, Morris L. Coprescription of terfenadine and erythromycin or ketaconazole: An assessment of potential harm: Pharmacists can be key in changing prescribing behavior to avoid drug-drug interactions. Science & Practice 1996;NS36:263-9.
-
(1996)
Science & Practice
, vol.NS36
, pp. 263-269
-
-
Carlson, A.1
Morris, L.2
-
29
-
-
0033811846
-
Cardiovascular adverse effects of antipsychotic drugs
-
Buckley NA, Sanders P. Cardiovascular adverse effects of antipsychotic drugs. Drug Safety 2000;23:215-28.
-
(2000)
Drug Safety
, vol.23
, pp. 215-228
-
-
Buckley, N.A.1
Sanders, P.2
-
30
-
-
0035021986
-
Evaluation of drug-induced QT interval prolongation: Implications for drug approval and labeling
-
Malik M, Camm AJ. Evaluation of drug-induced QT interval prolongation: Implications for drug approval and labeling. Drug Safety 2001;24:323-51.
-
(2001)
Drug Safety
, vol.24
, pp. 323-351
-
-
Malik, M.1
Camm, A.J.2
-
31
-
-
0034244378
-
The potential for QT prolongation and proarrhythmia by non-antiarrhythmic drugs: Clinical and regulatory implications
-
Harvekamp W, Breithardt G, Camm AJ, et al. The potential for QT prolongation and proarrhythmia by non-antiarrhythmic drugs: Clinical and regulatory implications. Eur Heart J 2000;21:1216-31.
-
(2000)
Eur Heart J
, vol.21
, pp. 1216-1231
-
-
Harvekamp, W.1
Breithardt, G.2
Camm, A.J.3
-
32
-
-
0034990035
-
Asymptomatic QTc prolongation associated with quetiapine fumarate overdose in a patient being treated with risperidone
-
Beelen AP, Yeo KT, Lewis LD. Asymptomatic QTc prolongation associated with quetiapine fumarate overdose in a patient being treated with risperidone. Hum Exp Toxicol 2001;20:215-9.
-
(2001)
Hum Exp Toxicol
, vol.20
, pp. 215-219
-
-
Beelen, A.P.1
Yeo, K.T.2
Lewis, L.D.3
-
34
-
-
0035150202
-
Antipsychotic drugs: Prolonged QTc interval, torsade de pointes, and sudden death
-
Glassman AH, Bigger JT Jr. Antipsychotic drugs: Prolonged QTc interval, torsade de pointes, and sudden death. Am J Psychiatry 2001;158:1774-82.
-
(2001)
Am J Psychiatry
, vol.158
, pp. 1774-1782
-
-
Glassman, A.H.1
Bigger Jr., J.T.2
-
35
-
-
0036139125
-
Electrophysiologic characterization of the antipsychotic drug sertindole in a rabbit heart model of torsade de pointes: Low torsadogenic potential despite QT prolongation
-
Eckardt L, Breithardt G, Haverkamp W. Electrophysiologic characterization of the antipsychotic drug sertindole in a rabbit heart model of torsade de pointes: Low torsadogenic potential despite QT prolongation. J Pharmacol Exp Ther 2002;300:64-71.
-
(2002)
J Pharmacol Exp Ther
, vol.300
, pp. 64-71
-
-
Eckardt, L.1
Breithardt, G.2
Haverkamp, W.3
-
36
-
-
0036263960
-
Thioridazine and sudden death in psychiatric in-patients
-
Reilly JG, Ayis SA, Ferrier IN, et al. Thioridazine and sudden death in psychiatric in-patients. Br J Psychiatry 2002;180:515-22.
-
(2002)
Br J Psychiatry
, vol.180
, pp. 515-522
-
-
Reilly, J.G.1
Ayis, S.A.2
Ferrier, I.N.3
|