Characterization of cell-type specific profiles in tissues and isolated cells from squamous cell carcinomas of the lung

Lung Cancer

Volumn 53, Issue 2, 2006, Pages 129-142

  Hawthorn, Lesleyann ^a   Stein, Leighton ^a   Panzarella, Jenniffer ^a   Loewen, Gregory M ^a   Baumann, Heinz ^a  

^a ROSWELL PARK CANCER INSTITUTE   (United States)

Author keywords

Expression profiles; Pathway analysis; Squamous cell carcinoma; Tissue heterogeneity

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE;

ARTICLE; CANCER GROWTH; CARCINOGENESIS; CELL DIFFERENTIATION; CELL HETEROGENEITY; CELL ISOLATION; CELL TYPE; CONTROLLED STUDY; DATA ANALYSIS; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG PARENCHYMA; LUNG SQUAMOUS CELL CARCINOMA; PRIORITY JOURNAL;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; BRONCHI; CARCINOMA, SQUAMOUS CELL; CELL LINE, TUMOR; DOWN-REGULATION; EPITHELIAL CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKIN-8; LUNG NEOPLASMS; MACROPHAGES, ALVEOLAR; MALE; MIDDLE AGED; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION;

EID: 33745622375     PISSN: 01695002     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lungcan.2006.04.015     Document Type: Article

References (54)

1. American Cancer Society. Cancer facts and figures (2003), American Cancer Society p. 23
2. Petty R.D., Nicolson M.C., Kerr K.M., Collie-Duguid E., and Murray G.I. Gene expression profiling in non-small cell lung cancer: from molecular mechanisms to clinical application. Clin Cancer Res 10 (2004) 3237-3248
3. Granville C.A., and Dennis P.A. An overview of lung cancer genomics and proteomics. Am J Respir Cell Mol Biol 32 (2005) 169-176
4. Bhattacharjee A., Richards W.G., Staunton J., Li C., Monti S., Vasa P., et al. Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses. Proc Natl Acad Sci USA 98 (2001) 13790-13795
5. Travis W.D., Colby T.V., Corrin B., Shimosato Y., and Brambilla E. World Health Organization classification of lung and pleural tumors (1999), Springer-Verlag, Berlin, Germany
6. Brambilla C., Fievet F., Jeanmart M., deFraipont F., Lantuejoul S., Frappat V., et al. Early detection of lung cancer: role of biomarkers. Eur Respir J 21 Suppl. 39 (2003) 36s-44s
7. Auerbach O., Garfinkel L., and Parks V.R. Scar cancer of the lung: increase over a 21-year period. Cancer 43 (1979) 636-642
8. Wistuba I.I., Behrens C., Virmani A.K., Mele G., Milchgrub S., Girard L., et al. High resolution chromosome 3p allelotyping of human lung cancer and preneoplastic/preinvasive bronchial epithelium reveals multiple, discontinuous sites of 3p allele loss and three regions of frequent breakpoints. Cancer Res 60 (2000) 1949-1960
9. Irizarry R.A., Hobbs B., Collin F., Beazer-Barclay Y.D., Antonellis K.J., Scherf U., et al. Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4 2 (2003) 249-264
10. Irizarry R.A., Bolstad B.M., Collin F., Cope L.M., Hobbs B., and Speed T.P. Summaries of Affymetrix GeneChip probe level data. Nucleic Acids Res 31 4 (2003) e15 24
11. Novichkova S., Egorov S., and Daraselia N. MedScan, a natural language processing engine for MEDLINE abstracts. Bioinformatics 19 13 (2003) 1699-1706
12. Cohen A., Guber A., Siegal A., Bruderman I., Huszar M., Yellin A., et al. The prognostic application of cytokeratin typing of nonsmall cell lung carcinoma. A retrospective study. Cancer 79 3 (1997) 468-473
13. van Dorst E.B., van Muijen G.N., Litvinov S.V., and Fleuren G.J. The limited difference between keratin patterns of squamous cell carcinomas and adenocarcinomas is explicable by both cell lineage and state of differentiation of tumour cells. J Clin Pathol 51 9 (1998) 679-684
14. Eckert R.L., Yaffe M.B., Crish J.F., Murthy S., Rorke E.A., and Welter J.F. Involucrin-structure and role in envelope assembly. J Invest Dermatol 100 5 (1993) 613-617
15. Backendorf C., and Hohl D. A common origin for cornified envelope proteins?. Nat Genet 2 2 (1992) 91
16. Gibbs S., Fijneman R., Wiegant J., van Kessel A.G., Putte P., van De C., et al. Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins 1. Genomics 16 3 (1993) 630-637
17. Tesfaigzi J., Th'ng J., Hotchkiss J.A., Harkema J.R., and Wright P.S. A small proline-rich protein, SPRR1, is upregulated early during tobacco smoke-induced squamous metaplasia in rat nasal epithelia. Am J Respir Cell Mol Biol 14 5 (1996) 478-486
18. Smith S.L., Watson S.G., Ratschiller D., Gugger M., Betticher D.C., and Heighway J. Maspin - the most commonly-expressed gene of the 18q21.3 serpin cluster in lung cancer - is strongly expressed in preneoplastic bronchial lesions. Oncogene 22 54 (2003) 8677-8687
19. Takeshima N., Suminami Y., Takeda O., Abe H., Okuno N., and Kato H. Expression of mRNA of SCC antigen in squamous cells. Tumour Biol 13 5-6 (1992) 338-342
20. Kato N. Clinical significance of SCC antigen assay as a tumor marker. Nippon Rinsho 48 Suppl. (1990) 1057-1059
21. Kim S., Han J., Kim J., and Park C. Maspin expression is transactivated by p63 and is critical for the modulation of lung cancer progression. Cancer Res 64 19 (2004) 6900-6905
22. Diederichs S., Bulk E., Steffen B., Ji P., Tickenbrock L., Lang K., et al. S100 family members and trypsinogens are predictors of distant metastasis and survival in early-stage non-small cell lung cancer. Cancer Res 64 16 (2004) 5564-5569
23. Smith S.L., Gugger M., Hoban P., Ratschiller D., Watson S.G., Field J.K., et al. S100A2 is strongly expressed in airway basal cells, preneoplastic bronchial lesions and primary non-small cell lung carcinomas. Br J Cancer 91 8 (2004) 1515-1524
24. Hibi K., Fujitake S., Takase T., Kodera Y., Ito K., Akiyama S., et al. Identification of S100A2 as a target of the DeltaNp63 oncogenic pathway. Clin Cancer Res 9 11 (2003) 4282-4285
25. Arai K., Teratani T., Kuruto-Niwa R., Yamada T., and Nozawa R. S100A9 expression in invasive ductal carcinoma of the breast: S100A9 expression in adenocarcinoma is closely associated with poor tumour differentiation. Eur J Cancer 40 8 (2004) 1179-1187
26. Ahmad D., Bayley L., He S., and Stockley R.A. Myeloid related protein-8/14 stimulates interleukin-8 production in airway epithelial cells. Am J Respir Cell Mol Biol 29 4 (2003) 523-530
27. Van Coillie E., Aelst Van I., Wuyts A., Vercauteren R., Devos R., Wolf-Peeters C., et al. Tumor angiogenesis induced by granulocyte chemotactic protein-2 as a countercurrent principle. Am J Pathol 159 4 (2001) 1405-1414
28. Smith D.R., Polverini P.J., Kunkel S.L., Orringer M.B., Whyte R.I., Burdick M.D., et al. Inhibition of interleukin 8 attenuates angiogenesis in bronchogenic carcinoma. J Exp Med 179 5 (1994) 1409-1415
29. Arenberg D.A., Kunkel S.L., Polverini P.J., Glass M., Burdick M.D., and Strieter R.M. Inhibition of interleukin-8 reduces tumorigenesis of human non-small cell lung cancer in SCID mice. J Clin Invest 97 12 (1996) 2792-2802
30. Zhu, Webster S.J., Flower D., and Woll P.J. Interleukin-8/CXCL8 is a growth factor for human lung cancer cells. Br J Cancer 91 11 (2004) 1970-1976
31. Keatings V.M., Collins P.D., Scott D.M., and Barnes P.J. Differences in interleukin-8 and tumor necrosis factor-alpha in induced sputum from patients with chronic obstructive pulmonary disease or asthma. Am J Respir Crit Care Med 153 2 (1996) 530-534
32. Traves S.L., Culpitt S.V., Russell R.E., Barnes P.J., and Donnelly L.E. Increased levels of the chemokines GROalpha and MCP-1 in sputum samples from patients with COPD. Thorax 57 7 (2002) 590-595
33. Wu D.Q., Kan M.K., Sato G.H., Okamoto T., and Sato J.D. Characterization and molecular cloning of a putative binding protein for heparin-binding growth factors. J Biol Chem 266 25 (1991) 16778-16785
34. Czubayko F., Smith R.V., Chung H.C., and Wellstein A. Tumor growth and angiogenesis induced by a secreted binding protein for fibroblast growth factors. J Biol Chem 269 45 (1994) 28243-28248
35. Aigner, Butscheid M., Kunkel P., Krause E., Lamszus K., Wellstein A., et al. An FGF-binding protein (FGF-BP) exerts its biological function by parallel paracrine stimulation of tumor cell and endothelial cell proliferation through FGF-2 release. Int J Cancer 92 4 (2001) 510-517
36. Li W.M., and Chen W.B. Effect of FGF-BP on angiogenesis in squamous cell carcinoma. Chin Med J (Engl) 117 4 (2004) 621-623
37. Wu B., Wang B., Gil J., Sabo E., Miller L., Gan L., et al. p63 and TTF-1 immunostaining. A useful marker panel for distinguishing small cell carcinoma of lung from poorly differentiated squamous cell carcinoma of lung. Am J Clin Pathol 119 5 (2003) 696-702
38. Yu Y.W., Garber M.E., Schluns K., Pacyna-Gengelbach M., and Petersen I. Evaluation of p63 expression in lung cancer by use of complementary DNA and tissue microarray. Zhonghua Bing Li Xue Za Zhi 33 4 (2004) 324-327
39. Au N.H., Cheang M., Huntsman D.G., Yorida E., Coldman A., Elliot W.M., et al. Evalauation of immunohistochemical markers in non-small cell lung cancer by unsupervised hierarchical clustering analysis: a tissue microarray study of 244 cases and 18 markers. J Pathol 204 1 (2004) 101-109
40. Massion P.P., Taflan P.M., Jamshedur Rahman S.M., Yildiz P., Shyr Y., Edgerton M.E., et al. Significance of p63 amplification and overexpression in lung cancer development and prognosis. Cancer Res 63 21 (2003) 7113-7121
41. Cano E., Hazzalin C.A., Kardalinou E., Buckle R.S., and Mahadevan L.C. Neither ERK nor JNK/SAPK MAP kinase subtypes are essential for histone H3/HMG-14 phosphorylation or c-fos and c-jun induction. J Cell Sci 108 Pt 11 (1995) 3599-3609
42. Pearson G., Robinson F., Gibson T., Beers B.E., Xu M., Karandikar K., et al. Mitogen-activated protein (MAP) kinase pathways: regulation and physiological functions. Endocr Rev 22 2 (2001) 153-183
43. Mukohara T., Kudoh S., Yamauchi S., Kimura T., Yoshimura N., Kanazawa H., et al. Expression of epidermal growth factor receptor (EGFR) and downstream-activated peptides in surgically excised non-smallcell lung cancer (NSCLC). Lung Cancer 41 2 (2003) 123-130
44. Vicent S., Garayoa M., Lopez-Picazo J.M., Lozano M.D., Toledo G., Thunnissen F.B., et al. Mitogen-activated protein kinase phosphatase-1 is overexpressed in non-small cell lung cancer and is an independent predictor of outcome in patients. Clin Cancer Res 10 11 (2004) 3639-3649
45. Hopkinson S.B., and Jones J.C. The N terminus of the transmembrane protein BP180 interacts with the N-terminal domain of BP230, thereby mediating keratin cytoskeleton anchorage to the cell surface at the site of the hemidesmosome. Mol Biol Cell 11 1 (2000) 277-286
46. Kikuchi T., Ichimiya S., Kojima T., Crisa L., Koshiba S., Tonooka A., et al. Expression profiles and functional implications of p53-like transcription factors in thymic epithelial cell subtypes. Int Immunol 16 6 (2004) 831-841
47. Gujral, Burton D.W., Terkeltaub R., and Deftos L.J. Parathyroid hormone-related protein induces interleukin 8 production by prostate cancer cells via a novel intracrine mechanismnot mediated by its classical nuclear localization sequence. Cancer Res 61 5 (2001) 2282-2288
48. Zhao D., Keates A.C., Kuhnt-Moore S., Moyer M.P., Kelly C.P., and Pothoulakis C. Signal transduction pathways mediating neurotensin-stimulated interleukin-8 expression in human colonocytes. J Biol Chem 276 48 (2001) 44464-44471
49. Henriksen P.A., Devitt A., Kotelevtsev Y., and Sallenave J.M. Gene delivery of the elastase inhibitor elafin protects macrophages from neutrophil elastase-mediated impairment of apoptotic cell recognition. FEBS Lett 574 1-3 (2004) 80-84
50. DeForge L.E., Fantone J.C., Kenney J.S., and Remick D.G. Oxygen radical scavengers selectively inhibit interleukin 8 production in human whole blood. J Clin Invest 90 5 (1992) 2123-2129
51. Hobbs R.M., and Watt F.M. Regulation of interleukin-1alpha expression by integrins and epidermal growth factor receptor in keratinocytes from a mouse model of inflammatory skin disease. J Biol Chem 278 22 (2003) 19798-19807
52. Krisanaprakornkit S., Kimball J.R., Weinberg A., Darveau R.P., Bainbridge B.W., and Dale B.A. Inducible expression of human beta-defensin 2 by Fusobacterium nucleatum in oral epithelial cells: multiple signaling pathways and role of commensal bacteria in innate immunity and the epithelial barrier. Infect Immun 68 5 (2000) 2907-2915
53. Sakamoto N., Mukae H., Fujii T., Ishii H., Yoshioka S., Kakugawa T., et al. Differential effects of alpha- and betadefensin on cytokine production by cultured human bronchial epithelial cells. Am J Physiol Lung Cell Mol Physiol 288 3 (2005) L508-L513
54. Chen J.J.W., Yao P., Yuan A., Hong T., Shun C., Kuo M., et al. Up-regulation of tumor interleukin-8 expression by infiltrating macrophages: its correlation with tumor angiogenesis and patient survival in non-small cell lung cancer. Clin Cancer Res 9 (2003) 729-737