Capillary electrophoresis contributions to the hydromorphone metabolism in man

Electrophoresis

Volumn 27, Issue 12, 2006, Pages 2444-2457

  Baldacci, Andrea ^a   Thormann, Wolfgang ^a  

^a UNIVERSITY OF BERN   (Switzerland)

Author keywords

CE MS; Hydromorphol; N oxide; O glucide; O glucuronide

Indexed keywords

BIOMOLECULES; BODY FLUIDS; CAPILLARY ELECTROPHORESIS; CHLORINE COMPOUNDS; GLUCOSE; ISOMERS; MASS SPECTROMETRY; PLANTS (BOTANY); STEREOCHEMISTRY;

CE-MS; EFFECTIVE TOOL; GLUCURONIDES; HYDROMORPHOL; MULTI-STAGES; N-OXIDES; O-GLUCIDE; O-GLUCURONIDE; PHASE I; PHASE II;

METABOLITES;

ALPHA HYDROMORPHOL; BETA HYDROMORPHOL; CYTOCHROME P450 3A4; DRUG METABOLITE; GLUCOSE; GLUCURONIC ACID; HEPTAKIS(2,6 O DIMETHYL) BETA CYCLODEXTRIN; HYDROMORPHOL; HYDROMORPHOL N OXIDE; HYDROMORPHONE; HYDROMORPHONE N OXIDE; NORHYDROMORPHOL; NORHYDROMORPHOL N OXIDE; NORHYDROMORPHONE; NORHYDROMORPHONE N OXIDE; OXYCODONE; SULFURIC ACID; UNCLASSIFIED DRUG;

ARTICLE; CAPILLARY ELECTROPHORESIS; COMPUTER PROGRAM; COMPUTER SIMULATION; CONTROLLED STUDY; DEMETHYLATION; DOSE RESPONSE; DRUG DECOMPOSITION; DRUG EXCRETION; DRUG HYDROLYSIS; DRUG IDENTIFICATION; DRUG METABOLISM; DRUG OXIDATION; DRUG STRUCTURE; DRUG URINE LEVEL; HUMAN; IN VITRO STUDY; MASS SPECTROMETRY; STEREOISOMERISM; URINALYSIS; URINARY EXCRETION;

EID: 33745614288     PISSN: 01730835     EISSN: 15222683     Source Type: Journal    
DOI: 10.1002/elps.200500867     Document Type: Article

References (35)

1. Sarhill, N., Walsh, D., Nelson, K. A., Support Care Cancer 2001, 9, 84-96.
2. Inturrisi, C. E., Clin. J. Pain 2002, 18, S3-S13.
3. Quigley, C., Wiffen, P., J. Pain Symptom. Manage. 2003, 25, 169-178.
4. Murray, A., Hagen, N. A., J. Pain Symptom. Manage. 2005, 29, S57-S66.
5. Grosset, A. B., Roberts, M. S., Woodson, M. E., Shi, M. et al., J. Pain Symptom. Manage. 2005, 29, 584-594.
6. Baselt, R. C., Cravey, R. H., Disposition of Toxic Drugs and Chemicals in Man, 4th Edn., Chemical Toxicology Institute, Foster City, CA 1995, pp. 385-385.
7. Gilson, A. M., Ryan, K. M., Joranson, D. E., Dahl, J. L., J. Pain Symptom. Manage. 2004, 28, 176-188.
8. Cicero, T. J., Inciardi, J. A., Munoz, A., J. Pain 2005, 6, 662-672.
9. Zheng, M., McErlane, K. M., Ong, M. C., Xenobiotica 2002, 32, 427-439.
10. Zheng, M., McErlane, K. M., Ong, M. C., Life Sci. 2004, 75, 3129-3146.
11. Benetton, S. A., Borges, V. M., Chang, T. K. H., McErlane, K. M., Xenobiotica 2004, 34, 335-344.
12. Cone, E. J., Phelps, B. A., Gorodetzky, C. W., J. Pharm. Sci. 1977, 66, 1709-1713.
13. Zheng, M., McErlane, K. M., Ong, M. C., Xenobiotica 2002, 32, 141-151.
14. Wright, A. W. E., Mather, L. E., Smith, M. T., Life Sci. 2001, 69, 409-420.
15. Lötsch, J., J. Pain Symptom. Manage. 2005, 29, S10-S24.
16. Ritschel, W. A., Parab, P. V., Denson, D. D., Coyle, D. E., Gregg, R. V., J. Clin. Pharmacol. 1987, 27, 647-653.
17. Parab, P. V., Ritschel, W. A., Coyle, D. E., Gregg, R. V., Denson, D. D., Biopharm. Drug Dispos. 1988, 9, 187-188.
18. Vashi, V., Harris, S., El-Tahtawy, A., Wu, D., Cipriano, A., J. Clin. Pharmacol. 2005, 45, 547-554.
19. Meatherall, R., J. Anal. Toxicol. 1999, 23, 177-186.
20. Nowatzke, W., Zeng, J., Saunders, A., Bohrer, A. et al., J. Pharm. Biomed. Anal. 1999, 20, 815-828.
21. Jones, J., Tomlinson, K., Moore, C., J. Anal. Toxicol. 2002, 26, 171-175.
22. Meatherall, R., J. Anal. Toxicol. 2005, 29, 301-308.
23. Lewis, R. J., Johnson, R. D., Hattrup, R. A., J. Chromatogr. B 2005, 822, 137-145.
24. Chang, S.-F, Moore, L., Chien, Y. W., Pharm. Res. 1988, 5, 718-721.
25. Hufschmid, E., Theurillat, R., Martin, U., Thormann, W., J. Chromatogr. B 1995, 668, 159-170.
26. Hufschmid, E., Theurillat, R., Wilder-Smith, C. H., Thormann, W., J. Chromatogr. B 1996, 678, 43-51.
27. Zhang, C.-X., Thormann, W., Anal. Chem. 1998, 70, 540-548.
28. Wey, A. B., Caslavska, J., Thormann, W., J. Chromatogr. A 2000, 895, 133-146.
29. Wey, A. B., Thormann, W., J. Chromatogr. A 2001, 916, 225-238.
30. Wey, A. B., Thormann, W., J. Chromatogr. B 2002, 770, 191-205.
31. Baldacci, A., Caslavska, J., Wey, A. B., Thormann, W., J. Chromatogr. A 2004, 1051, 273-282.
32. Baldacci, A., Thormann, W., Electrophoresis 2005, 26, 1969-1977.
33. Hahn, E. F., Fishman, J., J. Org. Chem. 1975, 40, 31-34.
34. Cymerman Craig, J., Purushothaman, K. K., J. Org. Chem. 1970, 35, 1721-1722.
35. Chen, X. Y., Zhao, L. M., Zhong, D. F., J. Clin. Pharmacol. 2003, 55, 570-578.