Isolation and identification of 2α,25-dihydroxyvitamin D3, a new metabolite from Pseudonocardia autotrophica 100U-19 cells incubated with Vitamin D3

Steroids

Volumn 71, Issue 8, 2006, Pages 736-744

  Takeda, Koji ^a   Kominato, Kaichiro ^a   Sugita, Atsuko ^b   Iwasaki, Yukiko ^c   Shimazaki, Mika ^c   Shimizu, Masato ^c  

^a MERCIAN CORPORATION   (Japan)

^b CHUGAI PHARMACEUTICAL CO LTD   (Japan)

^c TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

2 ,25 Dihydroxyvitamin D3; Microbial hydroxylation; Pseudonocardia autotrophica; Vitamin D receptor; Vitamin D binding protein

Indexed keywords

2ALPHA,25 DIHYDROXYVITAMIN D3; COLECALCIFEROL; COLECALCIFEROL DERIVATIVE; UNCLASSIFIED DRUG; CALCIFEDIOL; CALCITRIOL RECEPTOR; CARRIER PROTEIN; DRUG DERIVATIVE; ISOPROTEIN;

ANIMAL CELL; ARTICLE; CHROMATOGRAPHY; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG ISOLATION; DRUG STRUCTURE; EXPERIMENT; HUMAN; HUMAN CELL; HYDROXYLATION; MASS SPECTROMETRY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PSEUDONOCARDIA AUTOTROPHICA; PSEUDONOCARDIACEAE; ULTRAVIOLET SPECTROSCOPY; ANIMAL; BIOLOGICAL MODEL; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRAIN COS1; CELL STRAIN HL 60; CERCOPITHECUS; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; DRUG EFFECT; GENE EXPRESSION REGULATION; ISOLATION AND PURIFICATION; KERATINOCYTE; METABOLISM; NOCARDIA; STRUCTURE ACTIVITY RELATION;

PSEUDONOCARDIA AUTOTROPHICA;

ANIMALS; CALCIFEDIOL; CARRIER PROTEINS; CELL DIFFERENTIATION; CELL PROLIFERATION; CERCOPITHECUS AETHIOPS; CHOLECALCIFEROL; COS CELLS; GENE EXPRESSION REGULATION; HL-60 CELLS; HUMANS; HYDROXYLATION; KERATINOCYTES; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MOLECULAR CONFORMATION; NOCARDIA; PROTEIN ISOFORMS; RECEPTORS, CALCITRIOL; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33745611097     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.steroids.2006.05.004     Document Type: Article

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