Human brain astrocytes mediate TRAIL-mediated apoptosis after treatment with IFN-γ

Yonsei Medical Journal

Volumn 47, Issue 3, 2006, Pages 354-358

  Lee, Jeonggi ^a   Shin, Jeon Soo ^a   Choi, In Hong ^a  

^a Yonsei University   (South Korea)

Author keywords

Apoptosis; Astrocyte; IFN ; TRAIL

Indexed keywords

ALPHA INTERFERON; GAMMA INTERFERON; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

APOPTOSIS; ARTICLE; ASTROCYTE; BRAIN CELL; CELL CULTURE; CELL INFILTRATION; CONTROLLED STUDY; CYTOTOXICITY; ENCEPHALITIS; FETUS; HUMAN; HUMAN CELL; IMMUNOCOMPETENT CELL; PROTEIN EXPRESSION; PROTEIN INDUCTION; SENSITIVITY ANALYSIS;

EID: 33745600347     PISSN: 05135796     EISSN: 05135796     Source Type: Journal    
DOI: 10.3349/ymj.2006.47.3.354     Document Type: Article

References (18)

1. Bach JH, Chae HS, Rah JC, Lee MW, Park CH, Choi SH, et al. C-terminal fragment of amyloid precursor protein induces astrocytosis. J Neurochem 2001;78:109-20.
2. Andersson K, Olofsson A, Nielsen EH, Svehag SE, Lundgren E. Only amyloidogenic intermediates of transthyretin induce, apoptosis. Biochem Biophys Res Commun 2002;294:309-14.
3. Dowling P, Shang G, Raval S, Menonna J, Cook S, Husar W. Involvement of the CD95 (APO-1/Fas) receptor/ligand system in multiple sclerosis brain. J Exp Med 1996;184:1513-8.
4. Shi B, De Girolami U, He J, Wang S, Lorenzo A, Busciglio J, et al. Apoptosis induced by HIV-1 infection of the central nervous system. J Clin Invest 1996;98: 1979-90.
5. Wiley SR, Schooley K, Smolak PJ, Din WS, Huang CP, Nicholl JK, et al. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 1995;3:673-82.
6. Frank S, Kohler U, Schackert G, Schackert HK. Expression of TRAIL and its receptors in human brain tumors. Biochem Biophys Res Commun 1999;257:454-9.
7. Nakamura M, Rieger J, Weller M, Kim J, Kleihues P, Ohgaki H. APO2L/TRAIL expression in human brain tumors. Acta Neuropathol (Berl) 2000;99:1-6.
8. Rieger J, Ohgaki H, Kleihues P, Weller M. Human astrocytic brain tumors express AP02L/TRAIL. Acta Neuropathol (Berl) 1999;97:1-4.
9. Choi C, Park JY, Lee J, Shin EC, Ahn YS, Kim CH, et al. FasL and Fas are expressed constitutively in human astrocytes and the expression is increased with IL-1, IL-6, TNF-a or IFN-γ. J Immunol 1999; 162:1889-95.
10. Lee J, Shin JS, Park JY, Kwon D, Choi SJ, Kim SJ, et al. p38 mitogen-activated protein kinase modulates expression of tumor necrosis factor-related apoptosis-inducing ligand induced by interferon-gamma in fetal brain astrocytes. J Neurosci Res 2002;74:884-90.
11. Kayagaki N, Yamaguchi N, Nakayama M, Takeda K, Akiba H, Tsutsui H, et al. Expression and function of TNF-related apoptosis-inducing ligand on murine activated NK cells. J Immunol 1999;163:1906-13.
12. Eddleston M, Mucke L. Molecular profile of reactive astrocytes: implications for their role in neurologic disease. Neuroscience 1993;54:15-36.
13. Aloisi F, Borsellino G, Care A, Testa U, Gallo P, Russo C, et al. Cytokine regulation of astrocyte function: in-vitro studies using cells from the human brain. Int J Dev Neurosci 1995;13:265-74.
14. Dorr J, Bechmann I, Waiczies S, Aktas O, Walczak H, Krammer PH, et al. Lack of tumor necrosis factor-related apoptosis-inducing ligand but presence of its receptors in the human brain. J Neurosci 2002;22:RC209 (1-5).
15. Falsig J, Latta M, Leist M. Defined inflammatory states in astrocyte cultures: correlation with susceptibility towards CD95-driven apoptosis. J Neurochem 2004;88: 181-93.
16. Langaas V, Shahzidi S, Johnsen JI, Smedsrod B, Sveinbjornsson B. Interferon-gamma modulates TRAIL-mediated apoptosis in human colon carcinoma cells. Anti-cancer Res 2001;21:3733-8.
17. Griffith TS, Wiley SR, Kubin MZ, Sedger LM, Maliszewski CR, Fanger NA. Monocyte-mediated tumoricidal activity via the tumor necrosis factor-related cytokine. TRAIL. J Exp Med 1999;189:1343-54.
18. Smyth MJ, Cretney E, Takeda K, Wiltrout RH, Sedger LM, Kayagaki N, et al. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) contributes to interferon gamma-dependent natural killer cell protection from tumor metastasis. J Exp Med 2001;193:661-70.