Repeated lumbar sympathetic blockade with lidocaine and clonidine attenuates pain in complex regional pain syndrome type 1 patients - A report of two cases

Acta Anaesthesiologica Taiwanica

Volumn 44, Issue 2, 2006, Pages 113-117

  Chen, Liang Chih ^a,c   Wong, Chih Shung ^a   Huh, Billy K ^b   Huang, Yuan Shiou ^a   Yang, Chih Ping ^a,d   Yeh, Chun Chang ^a   Wu, Ching Tang ^a  

^a TRI SERVICE GENERAL HOSPITAL   (Taiwan)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c KAOHSIUNG ARMED FORCES GENERAL HOSPITAL   (Taiwan)

^d TAOYUAN ARMED FORCES GENERAL HOSPITAL   (Taiwan)

Author keywords

Autonomic nerve block; Clonidine; Complex Regional Pain Syndromes; Lidocaine

Indexed keywords

ANTICONVULSIVE AGENT; CLONIDINE; LIDOCAINE; OPIATE DERIVATIVE; TRICYCLIC ANTIDEPRESSANT AGENT;

ADULT; ANALGESIC ACTIVITY; ARTICLE; CASE REPORT; CLINICAL FEATURE; COMPLEX REGIONAL PAIN SYNDROME TYPE I; DIZZINESS; DRUG POTENTIATION; HUMAN; MALE; NEUROPATHIC PAIN; PAIN ASSESSMENT; PHYSIOTHERAPY; SEDATION; SIDE EFFECT; SYMPATHETIC BLOCKING; SYMPTOMATOLOGY; VISUAL ANALOG SCALE;

ADULT; AUTONOMIC NERVE BLOCK; CLONIDINE; COMPLEX REGIONAL PAIN SYNDROMES; HUMANS; LIDOCAINE; LUMBOSACRAL REGION; MALE;

EID: 33745589490     PISSN: 02541319     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (26)

1. Birklein F: Complex regional pain syndrome. J Neurol 252: 131-138, 2005.
2. Kozin F: Reflex sympathetic dystrophy syndrome: A review. Clin Exp Rheumat 10:401-409, 1992.
3. Teasell RW, Arnold JM: Alpha-1 adrenoceptor hyperresponsiveness in three neuropathic pain states: Complex regional pain syndrome 1, diabetic peripheral neuropathic pain and central pain states following spinal cord injury. Pain Res Manag 9:89-97, 2004.
4. Yung Chung O, Bruehl SP: Complex regional pain syndrome. Curr Treat Options Neurol 5:499-511, 2003.
5. Khan ZP, Ferguson CN, Jones RM: Alpha-2 and imidazoline receptor agonists: Their pharmacology and therapeutic role. Anaesthesia 54:146-165, 1999.
6. Leem JW, Choi Y, Han SM, Yoon MJ, Sim JY, Leem SW: Conduction block by clonidine is not mediated by 2-adrenergic receptors in rat sciatic nerve fibers. Reg Anesth Pain Med 25:620-625, 2000.
7. Kimura Y, Hamaguchi S, Okuda Y, Kitajima T: Addition of clonidine increases duration and magnitude of vasodilative effect induced by sympathetic block with mepivacaine in dogs. Reg Anesth Pain Med 26:329-332, 2001.
8. Erne-Brand F, Jirounek P, Drewe J, Hampl K, Schneider MC: Mechanism of antinociceptive action of clonidine in nonmyelinated nerve fibres. Eur J Pharmacol 383:1-8, 1999.
9. Kingery WS: A critical review of controlled clinical trials for peripheral neuropathic pain and complex regional pain syndromes. Pain 73:123-139, 1997.
10. Rauck RL, Eisenach JC, Jackson K, Young LD, Southern J: Epidural clonidine treatment for refractory reflex sympathetic dystrophy. Anesthesiology 79:1163-1169, 1993.
11. Dogrul A, Uzbay IT: Topical clonidine antinociception. Pain 111:385-391, 2004.
12. Cepeda MS, Lau J, Carr DB: Defining the therapeutic role of local anesthetic sympathetic blockade in complex regional pain syndrome: A narrative and systematic review. Clin J Pain 18:216-233, 2002.
13. Quisel A, Gill JM, Witherell P: Complex regional pain syndrome: Which treatments show promise? J Fam Pract 54:599-603, 2005.
14. Byas-Smith MG, Max MB, Muir J, Kingman A: Transdermal clonidine compared to placebo in painful diabetic neuropathy using a two-stage enriched enrollment design. Pain 60:267-274, 1995.
15. Davis KD, Treede RD, Raja SN, Meyer RA, Campbell JN: Topical application of clonidine relieves hyperalgesia in patients with sympathetically maintained pain. Pain 47:309-317, 1991.
16. Ongioco RR, Richardson CD, Rudner XL, Stafford-Smith M, Schwinn DA: Alpha2-adrenergic receptors in human dorsal root ganglia: Predominance of alpha2b and alpha2c subtype mRNAs. Anesthesiology 92:968-976, 2000.
17. Shi TS, Winzer-Serhan U, Leslie F, Hokfelt T: Distribution and regulation of alpha 2-adrenoceptors in rat dorsal root ganglia. Pain 84:319-330, 2000.
18. Jumblatt JE: Prejunctional alpha 2-adrenoceptors and adenylyl cyclase regulation in the rabbit iris-ciliary body. J Ocul Pharmacol 10:617-621, 1994.
19. Hargreaves KM, Jackson DL, Bowles WR: Adrenergic regulation of capsaicin-sensitive neurons in dental pulp. J Endod 29:397-399, 2003.
20. Gaumann DM, Brunet PC, Jirounek P: Clonidine enhances the effects of lidocaine on C-fiber action potential. Anesth Analg 74:719-725, 1992.
21. Butterworth JF 5th, Strichartz GR: The alpha 2-adrenergic agonists clonidine and guanfacine produce tonic and phasic block of conduction in rat sciatic nerve fibers. Anesth Analg 76:295-301, 1993.
22. Nakamura M, Ferreira SH: Peripheral analgesic action of clonidine: Mediation by release of endogenous enkephalin-like substances. Eur J Pharmacol 146:223-228, 1988.
23. Stein C, Comisel K, Haimerl E, Yassouridis A, Lehrberger K, Herz A, Peter K: Analgesic effect of intraarticular morphine after arthroscopic knee surgery. N Engl J Med 325:1123-1126, 1991.
24. +-loaded peripheral sympathetic nerves. Neurochem Int 45:699-711, 2004.
25. Milligan KR, Convery PN, Weir P, Quinn P, Connolly D: The efficacy and safety of epidural infusions of levobupivacaine with and without clonidine for postoperative pain relief in patients undergoing total hip replacement. Anesth Analg 91: 393-397, 2000.
26. Singelyn FJ, Dangoisse M, Bartholomee S, Gouverneur JM: Adding clonidine to mepivacaine prolongs the duration of anesthesia and analgesia after axillary brachial plexus block. Reg Anesth 17:148-150, 1992.