Influence of sequential oligopeptide carriers on the bioactive structure of conjugated epitopes: Comparative study of the conformation of a herpes simplex virus glycoprotein gD-1 epitope in the free and conjugated form, and protein "built-in" crystal structure

Biopolymers - Peptide Science Section

Volumn 84, Issue 4, 2006, Pages 383-399

  Krikorian, Dimitrios ^a   Stavrakoudis, Athanassios ^a   Biris, Nikolaos ^a   Sakarellos, Constantinos ^a   Andreu, David ^b   De Oliveira, Eliandre ^b,g   Mezö, Gábor ^c   Majer, Zsuzsa ^d   Hudecz, Ferenc ^c,d   Welling Wester, Sytske ^e   Cung, Manh Thong ^f   Tsikaris, Vassilios ^a  

^a UNIVERSITY OF IOANNINA   (Greece)

^b UNIVERSITAT POMPEU FABRA   (Spain)

^c EÖTVÖS LORÁND UNIVERSITY   (Hungary)

^d EÖTVÖS LORÁND UNIVERSITY   (Hungary)

^e UNIVERSITY OF GRONINGEN   (Netherlands)

^f LAB DE CHIM PHYS MACROMOLECULAIRE   (France)

^g Proteomics Platform   (Spain)

Author keywords

Carrier conjugated epitopes; Conformation of conjugated epitope peptides; Glycoprotein D 1 epitope; Sequential oligopeptide carriers; Synthetic carriers; Tetratuftsin carrier

Indexed keywords

AMINO ACIDS; CONFORMATIONS; CRYSTAL STRUCTURE; ETHERS; OLIGOMERS; PROTEINS; VIRUSES;

CARRIER-CONJUGATED EPITOPES; CONFORMATION OF CONJUGATED EPITOPE PEPTIDES; GLYCOPROTEIN D-1 EPITOPES; SEQUENTIAL OLIGOPEPTIDE CARRIERS; SYNTHETIC CARRIERS; TETRATUFTSIN CARRIER;

ORGANIC POLYMERS;

CARRIER PROTEIN; EPITOPE; GLYCOPROTEIN D; GLYCOPROTEIN D1; OLIGOPEPTIDE; UNCLASSIFIED DRUG; VIRUS PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; HERPES SIMPLEX VIRUS; IN VIVO STUDY; NONHUMAN; PROTON NUCLEAR MAGNETIC RESONANCE;

AMINO ACID SEQUENCE; BINDING SITES; CIRCULAR DICHROISM; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; EPITOPES; GLYCOPROTEINS; HERPESVIRUS 1, HUMAN; HYDROGEN BONDING; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; OLIGOPEPTIDES; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; TRIFLUOROETHANOL; WATER;

SIMPLEXVIRUS;

EID: 33745524890     PISSN: 00063525     EISSN: 10970282     Source Type: Journal    
DOI: 10.1002/bip.20486     Document Type: Article

References (45)

1. Tam, J. P. Proc Natl Acad Sci USA 1988, 85, 5409-5413.
2. Tam, J. P.; Lu, Y. A. Proc Natl Acad Sci USA 1989, 86, 9084-9088.
3. Tsikaris, V.; Sakarellos, C.; Cung, M. T.; Marraud, M.; Sakarellos-Daitsiotis, M. Biopolymers 1996, 38, 291-293.
4. Tsikaris, V.; Sakarellos, C.; Sakarellos-Daitsiotis, M.; Orlewski, P.; Marraud, M.; Cung, M. T.; Vatzaki, E.; Tzartos, S. Int J Biol Macromol 1996, 19, 195-205.
5. Tsikaris, V.; Sakarellos, C.; Sakarellos-Daitsiotis, M.; Cung, M. T.; Marraud, M.; Konidou, G.; Tzinia, A.; Soteriadou, K. P. Peptide Res 1996, 9, 240-247.
6. Hudecz, F.; Pimm, M. V.; Rajnavölgyi, E.; Mezö, G.; Fabra, A.; Gaál, D.; Kovács, A. L.; Horváth, A.; Szekerke, M. Bioconjugate Chem 1999, 10, 781-790.
7. Mezö, G.; Kajtár, J.; Nagy, I.; Szekerke, M.; Hudecz, F. Biopolymers 1997, 42, 719-730.
8. Hudecz, F. Biologicals 2001, 29, 197-207.
9. Mezö, G.; de Oliveira, E.; Krikorian, D.; Feijlbrief, M.; Jakab, A.; Tsikaris, V.; Sakarellos, C.; Welling-Wester, S.; Andreu, D.; Hudecz, F. Bioconjugate Chem 2003, 14, 1260-1269.
10. Haro, I.; Gömara, M. J. Curr Protein Pept Sci 2004, 5, 425-433.
11. Yiannaki, E. E.; Tzioufas, A. G.; Bachmann, M.; Hantoumi, J.; Tsikaris, V.; Sakarellos-Daitsiotis, M.; Sakarellos, C.; Moutsopoulos, H. M. Clin Exp Immunol 1998, 112, 152-158.
12. Alexopoulos, C.; Tsikaris, V.; Rizou, C.; Panou-Pomonis, E.; Sakarellos-Daitsiotis, M.; Sakarellos, C.; Vlachoyiannopoulos, P. G.; Moutsopoulos, H. M. J Peptide Sci 2001, 7, 105-114.
13. Wilkinson, K. A.; Vordermeier, M. H.; Wilkinson, R.; Iványi, J.; Hudecz, F. Bioconjugate Chem 1998, 9, 539-547.
14. Strongylis, C.; Voidarou, C.; Tsoukatos, D.; Naka, K.; Michails, L.; Soteriadou, K.; Sakarellos-Daitsiotis, M.; Sakarellos, C.; Tsikaris, V. J Peptide Sci 2004, 10(S2), 293.
15. Tsikaris, V.; Vlachoyiannopoulos, P. G.; Panou-Pomonis, E.; Marraud, M.; Sakarellos, C.; Moutsopoulos, H. M.; Sakarellos-Daitsiotis, M. Int J Peptide Protein Res 1996, 48, 319-327.
16. Sakarellos, C.; Tsikaris, V.; Panou-Pomonis, E.; Alexopoulos, C.; Sakarellos-Daitsiotis, M.; Petrovas, C.; Vlachoyiannopoulos, P. G.; Moutsopoulos, H. M. Lett Peptide Sci 1997, 4, 447-454.
17. Petrovas, C.; Vlachoyiannopoulos, P. G.; Tzioufas, A. G.; Alexopoulos, C.; Tsikaris, V.; Sakarellos-Daitsiotis, M.; Sakarellos, C.; Moutsopoulos, H. M. J Immunol Methods 1998, 220, 59-68.
18. Sakarellos-Daitsiotis, M.; Tsikaris, V.; Sakarellos, C.; Vlachoyiannopoulos, P. G.; Tzioufas, A. G.; Moutsopoulos, H. M. Vaccine 2000, 18, 302-310.
19. Sakarellos-Daitsiotis, M.; Tsikaris, V.; Vlachoyiannopoulos, P. G.; Tzioufas, A. G.; Moutsopoulos, H. M.; Sakarellos, C. Methods 1999, 19, 133-141.
20. Keramisanou, D.; Tsikaris, V.; Sakarellos-Daitsiotis, M.; Sakarellos, C.; Mikhailova, A. A.; Strelkov, L. A. J Peptide Res 2002, 60, 178-185.
21. Alexopoulos, C.; Tsikaris, V.; Rizou, C.; Sakarellos-Daitsiotis, M.; Sakarellos, C.; Cung, M. T.; Marraud, M.; Vlachoyiannopoulos, P. G.; Moutsopoulos, H. M. Biopolymers 2000, 54, 1-10.
22. Mezö, G.; Mezö, I.; Pimm, M. V.; Kajtár, J.; Seprödi, A.; Teplán, I.; Kovács, M.; Vincze, B.; Pályi, I.; Idei, M.; Szekerke, M.; Hudecz, F. Bioconjugate Chem 1996, 7, 642-650.
23. Mezö, G.; Kalászi, A.; Reményi, J.; Majer, Z.; Hubert, A.; Láng, O.; Köhidai, L.; Barna, K.; Gaál, D.; Hudecz, F. Biopolymers 2004, 73, 645-656.
24. Mezö, G.; Manea, M.; Jakab, A.; Kapuván, B.; Bösze, S.; Schlosser, G.; Przybylski, M.; Hudecz, F. J Peptide Sci 2004, 10, 701-713.
25. Mezö, G.; Mihala, N.; Andreu, D.; Hudecz, F. Bioconjugate Chem 2000, 11, 484-491.
26. Welling-Wester, S.; Feijlbrief, M.; Koedijk, D. G. A. M.; Drijfhout, J. W.; Weijer, A. J.; Scheffer, A. J.; Welling, G. W. Arch Virol 1994, 138, 331-340.
27. Eisenberg, R. J.; Long, D.; Ponce de Leon, M.; Matthews, J. T.; Spear, P. G.; Gibson, M. G.; Lasky, L. A.; Berman, P.; Golub, E.; Cohen, G. H. J Virol 1985, 53, 634-644.
28. Carfi, A.; Willis, S. H.; Whitbeck, J. C.; Krummenacker, C.; Cohen, G. H.; Eisenberg, R. J.; Wiley, D. C. Mol Cell 2001, 8, 169-179.
29. Kumar, A.; Wagner, G.; Ernst, R. R.; Wüthrich, K. J Am Chem Soc 1981, 103, 3654-3658.
30. Piotto, M.; Saudek, V.; Sklenar, V. J Biomol NMR 1992, 2, 661-665.
31. Sklenar, V.; Piotto, M.; Leppik, R.; Saudek, V. J Magn Reson 1993, 102A, 241-245.
32. Bartels, C.; Xia, T. H.; Billeter, M.; Güntert, P.; Wüthrich, K. J Biomol NMR 1995, 5, 1-10.
33. Heber-Katz, E.; Hollósi, M.; Dietzschold, B.; Hudecz, F.; Fasman, G. D. J Immunol 1985, 135, 1385-1390.
34. Güntert, P.; Mumenthaler, C.; Wüthrich, K. J Mol Biol 1997, 273, 283-298.
35. Herrmann, T.; Güntert, P.; Wüthrich, K. J Mol Biol 2002, 319, 209-227.
36. Koradi, R.; Billeter, M.; Wüthrich, K. J Mol Graphics 1996, 14, 51-55.
37. Wüthrich, K. In NMR of Proteins and Nucleic Acids; John Wiley & Sons: New York, 1986; pp 117-129.
38. Crisma, M.; Formaggio, F.; Moretto, A.; Toniolo, C. Biopolymers (Peptide Sci) 2006, 84, 3-12.
39. Williamson, M. P.; Handa, B. K.; Hall, M. J. Int J Peptide Protein Res 1986, 27, 562-568.
40. Williamson, M. P.; Handa, B. K.; Hall, M. J. Eur J Biochem 1986, 158, 527-536.
41. Sharman, G. J.; Griffiths-Jones, S. R.; Jourdan, M.; Searle, M. S. J Am Chem Soc 2001, 123, 12318-12324.
42. Beger, R. D.; Bolton, P. H. J Biomolecular NMR 1997, 10, 129-142.
43. Möhle, K.; Gussmann, M.; Hofmann, H.-J. J Comput Chem 1997, 18, 1415-1430.
44. Francis, A. K.; Iqbal, M.; Balaram, P. FEBS Lett 1983, 155, 230-232.
45. Sudha, T. S.; Vijayakumar, E. U.; Balaram, P. 1983, J Pept Protein Res 1983, 22, 464-468.