Chimeric peptide of met-enkephalin and FMRFa: Effect of chlorination on conformation and analgesia

Neuroscience Letters

Volumn 403, Issue 1-2, 2006, Pages 131-135

  Hanif, Kashif ^a   Gupta, Kshitij ^a   Gupta, Suparna ^a   Gupta, Y K ^b   Maiti, Souvik ^a   Pasha, Santosh ^a  

^a CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

^b ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

Author keywords

Analgesia; Bioavailability; Chimeric peptides; Chlorination

Indexed keywords

ANALGESIC AGENT; METENKEPHALIN DERIVATIVE; NALOXONE; OPIATE RECEPTOR; PEPTIDE; PHENYLALANINE; PHENYLALANYLMETHIONYLARGINYLPHENYLALANINAMIDE; SOLVENT; TRIFLUOROETHANOL; TYROSYLGLYCYLGLYCYLPHENYLALANYLMETHIONYLLYSYLLYSYLPHENYLALANYLMETHIONYL ARGINYLPHENYLALANINAMIDE; UNCLASSIFIED DRUG;

ALPHA HELIX; ANALGESIA; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ARTICLE; CHLORINATION; COMPARATIVE STUDY; CONTROLLED STUDY; DESENSITIZATION; DOSE RESPONSE; DRUG ACTIVITY; DRUG ANTAGONISM; DRUG BIOAVAILABILITY; DRUG CONFORMATION; LIPOPHILICITY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN MODIFICATION; STRUCTURE ACTIVITY RELATION; TAIL FLICK TEST;

ANALGESIA; ANALGESICS, OPIOID; ANIMALS; CIRCULAR DICHROISM; ENKEPHALIN, METHIONINE; FMRFAMIDE; MALE; MICE; OCTANOLS; OLIGOPEPTIDES; PAIN; PROTEIN STRUCTURE, SECONDARY; SOLUBILITY; WATER;

EID: 33745484603     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2006.04.029     Document Type: Article

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