Estrogen receptor 1 haplotype does not regulate oral contraceptive-induced changes in haemostasis and inflammation risk factors for venous and arterial thrombosis

Human Reproduction

Volumn 21, Issue 6, 2006, Pages 1473-1476

  de Maat, Moniek P M ^a,b   Bladbjerg, E M ^a   Kluft, C ^a,c   Winkler, U H ^d   Rekers, H ^e   Skouby, S O ^f   Jespersen, J ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

^b ERASMUS MEDICAL CENTER   (Netherlands)

^c TNO   (Netherlands)

^d Klinikum Wetzlar Braunfels   (Germany)

^e NV ORGANON   (Netherlands)

^f UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Estrogen receptor 1; Haemostasis; Inflammation; Oral contraceptives; Polymorphism

Indexed keywords

CYTOSINE; ESTROGEN; ESTROGEN RECEPTOR; ESTROGEN RECEPTOR 1; GLUTAMIC ACID; ORAL CONTRACEPTIVE AGENT; TISSUE PLASMINOGEN ACTIVATOR; UNCLASSIFIED DRUG;

ADULT; ARTERY THROMBOSIS; ARTICLE; BLOOD SAMPLING; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG DOSE REGIMEN; FEMALE; GENETIC VARIABILITY; GENOTYPE; HAPLOTYPE; HEMOSTASIS; HUMAN; INFLAMMATION; MAJOR CLINICAL STUDY; MULTICENTER STUDY; NULLIPARA; OPEN STUDY; PARALLEL DESIGN; RANDOMIZED CONTROLLED TRIAL; RISK FACTOR; SINGLE NUCLEOTIDE POLYMORPHISM; VEIN THROMBOSIS;

EID: 33745474648     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/del015     Document Type: Article

References (16)

1. Bladbjerg EM, Gram J, Jespersen J and de Maat MP (2002) Internal quality control of PCR-based genotyping methods in research studies and patient diagnostics. Thromb Haemost 87,812-816.
2. Herrington DM (2003) Role of estrogen receptor-alpha in pharmacogenetics of estrogen action. Curr Opin Lipidol 14,145-150.
3. Herrington DM, Howard TD, Hawkins GA, Reboussin DM, Xu J, Zheng SL, Brosnihan KB, Meyers DA and Bleecker ER (2002a) Estrogen-receptor polymorphisms and effects of estrogen replacement on high-density lipoprotein cholesterol in women with coronary disease. N Engl J Med 346,967-974.
4. Herrington DM, Howard TD, Brosnihan KB, McDonnell DP, Li X, Hawkins GA, Reboussin DM, Xu J, Zheng SL, Meyers DA et al. (2002b) Common estrogen receptor polymorphism augments effects of hormone replacement therapy on E-selectin but not C-reactive protein. Circulation 105,1879-1882.
5. Leiden mutation: A randomized trial. Blood 103,927-933.
6. Kobayashi S, Inoue S, Hosoi T, Ouchi Y, Shiraki M and Orimo H (1996) Association of bone mineral density with polymorphism of the estrogen receptor gene. J Bone Miner Res 11,306-311.
7. Koch W, Hoppmann P, Pfeufer A, Mueller JC, Schomig A and Kastrati A (2005) No replication of association between estrogen receptor alpha gene polymorphisms and susceptibility to myocardial infarction in a large sample of patients of European descent. Circulation 112,2138-2142.
8. Rosing J, Tans G, Nicolaes GA, Thomassen MC, van Oerle R, van der Ploeg PM, Heijnen P, Hamulyak K and Hemker HC (1997) Oral contraceptives and venous thrombosis: Different sensitivities to activated protein C in women using second- and third-generation oral contraceptives. Br J Haematol 97,233-238.
9. Schindler AE (2003) Differential effects of progestins on hemostasis. Maturitas 46 (Suppl. 1), S31-S37.
10. Schuit SC, Oei HH, Witteman JC, Geurts van Kessel CH, van Meurs JB, Nijhuis RL, van Leeuwen JP, de Jong FH, Zillikens MC, Hofman A et al. (2004) Estrogen receptor alpha gene polymorphisms and risk of myocardial infarction. JAMA 291,2969-2977.
11. Shearman AM, Cupples LA, Demissie S, Peter I, Schmid CH, Karas RH, Mendelsohn ME, Housman DE and Levy D (2003) Association between estrogen receptor alpha gene variation and cardiovascular disease. JAMA 290,2263-2270.
12. Straczek C, Alhenc-Gelas M, Aubry ML and Scarabin PY (2005) Genetic variation at the estrogen receptor alpha locus in relation to venous thromboembolism risk among postmenopausal women. J Thromb Haemost 3,1535-1537.
13. Tans G, Bouma BN, Buller HR and Rosing J (2003) Changes of hemostatic variables during oral contraceptive use. Semin Vasc Med 3,61-68.
14. The Oral Contraceptive and Hemostasis Study Group (1999) An open label, randomized study to evaluate the effects of seven monophasic oral contraceptive regimens on hemostatic variables. Outline of the protocol. Contraception 59,345-355.
15. The Oral Contraceptive and Hemostasis Study Group (2003) The effects of seven monophasic oral contraceptive regimens on hemostatic variables: conclusions from a large randomized multicenter study. Contraception 67, 173-185.
16. Thijs A and Stehouwer CD (2003) Changes of hemostatic variables during hormone replacement therapy. Semin Vasc Med 3,85-92.