No replication of association between estrogen receptor α gene polymorphisms and susceptibility to myocardial infarction in a large sample of patients of European descent

Circulation

Volumn 112, Issue 14, 2005, Pages 2138-2142

  Koch, Werner ^a,c   Hoppmann, Petra ^a   Pfeufer, Arne ^a,b   Mueller, Jakob C ^a   Schömig, Albert ^a   Kastrati, Adnan ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

Estrogen receptor alpha; Genetics; Myocardial infarction; Polymorphism; Receptors, estrogen

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR ALPHA; TAQ POLYMERASE;

ADULT; AGED; ANGIOCARDIOGRAPHY; ARTICLE; BIOASSAY; CAUCASIAN; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY RISK; DIPLOTYPE; ESR1 GENE; ESTROGEN ACTIVITY; EUROPE; EUROPEAN; EUROPEAN DESCENT; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC LINE; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HEART INFARCTION; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROTEIN SYNTHESIS; RECEPTOR GENE; SINGLE NUCLEOTIDE POLYMORPHISM;

AGED; DISEASE SUSCEPTIBILITY; DNA PRIMERS; ESTROGEN RECEPTOR ALPHA; EUROPE; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENOTYPE; GERMANY; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; POLYMORPHISM, SINGLE NUCLEOTIDE; REFERENCE VALUES; RESTRICTION MAPPING; SEQUENCE DELETION; SMOKING;

EID: 26944461954     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.105.545913     Document Type: Article

References (27)

1. Mendelsohn ME, Karas RH. The protective effects of estrogen on the cardiovascular system. N Engl J Med. 1999;340:1801-1811.
2. Darbladc B, Pendaries C, Krust A, Dupont S, Fouque M-J, Rami J, Chambon P, Bayard F, Arnal J-F. Estradiol alters nitric oxide production in the mouse aorta through the α-, but not β-, estrogen receptor. Circ Res. 2002;90:413-419.
3. Brauchet L, Krust A, Dupont S, Chambon P, Bayard F, Arnal JF. Estradiol accelerates reendothelialization in mouse carotid arten1 through estrogen receptor-α but not estrogen receptor-β. Circulation. 2001;103:423-428.
4. Pare G, Krust A, Karas RH, Dupont S, Aronovitz M, Chambon P, Mendelsohn ME. Estrogen receptor-α mediates the protective effects of estrogen against vascular injury. Circ Res. 2002;90:1087-1092.
5. Sudhir K, Chou TM, Messina LM, Hutchison SJ, Korach KS, Chatterjce K, Rubanyi GM. Endothelial dysfunction in a man with disruptive mutation in oestrogen-receptor gene. Lancet. 1997;349:1146-1147.
6. Sudhir K, Chou TM, Chatterjee K, Smith EP, Williams TC, Kane JP, Malloy MJ, Korach KS, Rubanyi GM. Premature coronary artery disease associated with a disruptive mutation in the estrogen receptor gene in a man. Circulation. 1997;96:3774-3777.
7. Matsubara Y, Murata M, Kawano K, Zama T, Aoki N, Yoshino H, Watanabe G, Ishikawa K, Ikeda Y. Genotype distribution of estrogen receptor polymorphisms in men and postmenopausal women from healthy and coronary populations and its relation to serum lipid levels. Arterioscler Thromb Vasc Biol. 1997;17:3006-3012.
8. Lehtimäki T, Kunnas TA, Mattila KM, Perola M, Penttilä A, Koivula T, Karhuncn PJ. Coronary artery wall atherosclerosis in relation to the cstrogcn receptor I gene polymorphism: an autopsy study. J Mol Med. 2002;80:176-180.
9. Lu H, Higashikata T, Inazu A, Noharu A, Yu W, Shimizu M, Mabuchi H. Association of estrogen receptor-α gene polymorphisms with coronary artery disease in patients with familial hypercholesterolemia. Arterioscler Thromb Vasc Biol. 2002;22:817-823.
10. Shearman AM, Cupples LA, Demissie S, Peter I, Schmid CH, Karas RH, Mcndelsohn ME, Housman DE, Levy D. Association between cstrugen receptor gene variation and cardiovascular disease. JAMA. 2003;290:2263-2270.
11. Schuil SCE, Oei H-HS, Witteman JCM, Geurts van Kessel CH, van Meurs JBJ, Nijhuis RL, van Leeuwen JPTM, de Jong FH, Zillikens MC, Hofman A, Pols HAP, Uitterlinden AG. Estrogen receptor α gene polymorphisms and risk of myocardial infarction. JAMA. 2004;291: 2969-2977.
12. World Medical Association Declaration of Helsinki: recommendations guiding physicians in biomedical research involving human subjects. JAMA 1997;277:925-926.
13. Guidelines Subcommittee. 1999 World Health Organization-International Society of Hypertension Guidelines for the Management of Hypertension. J Hypertens. 1999;17:151-183.
14. World Health Organization Study Group. Diabetes mellitus. WHO Tech Rep Ser. 1985;727:1-104.
15. Livak KJ. Allelic discrimination using fluorogenic probes and the 5′ nuclease assay. Genet. 1999;14:143-149.
16. Kutyavin IV, Afonina IA, Mills A, Gom VV, Lukhiunov EA, Belousov ES, Singer MJ, Walhurger DK, Lokhov SG, Gall AA, Dempey R, Reed MW, Meyer RB, Hedgpeth J. 3′-Minor groove binder-DNA probes increase sequence specificity at PCR extension temperatures. Nucleic Acids Res 2000;28:655-661.
17. Barrett JC, Fry B, Maller J, Daly MJ, Haploview: analysis and visualization of LD and haplotype maps. Bioinformatics. 2005;21:263-265.
18. Albagha OME, McGuigan FEA, Reid DM, Ralston SH. Estrogen receptor α gene polymorphisms and bone mineral density: haplotype analysis in women from the United Kingdom. J Bone Miner Res. 2001;16:128-134.
19. Dcng H-W, Li J, Li J-L, Johnson M, Gong G, Recker RR. Association of VDR and estrogen receptor genotypes with bone mass in postmenopausal Caucasian women: different conclusions with different analyses and the implications. Osteoporos Int. 1999;9:499-507.
20. Kohayashi S, Inoue S, Hosoi T, Ouchi Y, Shiraki M, Orimo H. Association of bone mineral density with polymorphism of the estrogen receptor gene. J Bone Miner Res. 1996;11:306-311.
21. Freely associating |editorial|. Nat Genet. 1999;22:1-2.
22. Lohmueller KE, Pearce CL, Pike M, Lander ES, Hirschhorn JN. Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to commun disease. Nat Genet. 2003;33:177-181.
23. Hegele RA. SNP judgments and freedom of association. Arterioscler Thromb Vasc Biol. 2002;22:1058-1061.
24. Ozaki K, Ohnishi Y, Iida A, Sekine A, Yamada R, Tsunoda T, Sato H, Sato H, Hori M, Nakamura Y, Tanaka T. Functional SNPs in the lymphotoxin-α gene that are associated with susceptibility to myocardial infarction. Natl Genet. 2002;32:650-654.
25. Yamada Y, Izawa H, Ichihara S, Takatsu F, Ishihara H, Hirayama H, Sone T, Tanaka M, Yokota M. Prediction of the risk of myocardial infarction from polymorphisms in candidate genes. N Engl J Med. 2002; 347:1916-1923.
26. Helgadottir A, Manolescu A, Thorleifsson G, Gretarsdottir S, Jonsdottir H, Thorsteinsdottir U, Samani NJ, Gudmundsson G, Grant SFA, Thorgeirsson G. Sveinhjornsdottir S, Valdimarsson EM, Matthiasson SE, Johannsson H, Gudmundsdottir O, Gumey ME, Sainz, J, Thorhallsdottir M, Andresdottir M, Frigge ML, Topol EJ, Kong A, Gudnason V, Hakonarson H, Gulcher JR, Stefansson K. The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke. Mil Genet. 2004;36:233-239.
27. Becherini L, Gennari L, Masi L, Mansani R, Massart F, Morelli A, Falchetti A, Gonnelli S, Fiorelli G, Tanini A, Brandi ML. Evidence of a linkage disequilibrium between polymorphisms in the human estrogen receptor α gene and their relationship to bone mass variation in postmenopausal Italian women. Hum Mol Genet. 2000;9:2043-2050.