Evidence that maturation of the N-linked glycans of the respiratory syncytial virus (RSV) glycoproteins is required for virus-mediated cell fusion: The effect of α-mannosidase inhibitors on RSV infectivity

Virology

Volumn 350, Issue 2, 2006, Pages 289-301

  McDonald, Terence P ^a   Jeffree, Chris E ^b   Li, Ping ^a   Rixon, Helen W McL ^a   Brown, Gaie ^a   Aitken, James D ^c   MacLellan, Kirsty ^a   Sugrue, Richard J ^a  

^a INSTITUTE OF VIROLOGY   (United Kingdom)

^b UNIVERSITY OF EDINBURGH   (United Kingdom)

^c UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

Deoxymannojirimycin; Fusion protein; Glycosylation; Proteomics; Respiratory syncytial virus; Swainsonine; Virus assembly

Indexed keywords

1 DEOXYMANNONOJIRIMYCIN; ALPHA MANNOSIDASE; GLYCAN; GLYCOSIDASE INHIBITOR; GUANINE NUCLEOTIDE BINDING PROTEIN; SWAINSONINE; UNCLASSIFIED DRUG; VIRUS GLYCOPROTEIN; VIRUS PROTEIN; VIRUS PROTEIN F;

ANIMAL CELL; ARTICLE; CELL FUSION; CONTROLLED STUDY; CORRELATION ANALYSIS; EMBRYO; EVIDENCE BASED MEDICINE; GENETIC HETEROGENEITY; MATURATION; NONHUMAN; PRIORITY JOURNAL; PROGENY; PROTEIN PROCESSING; PROTEOMICS; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; VIRUS CELL INTERACTION; VIRUS INFECTIVITY;

ALPHA-MANNOSIDASE; CELL FUSION; CELL LINE, TUMOR; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ENZYME INHIBITORS; GLYCOPROTEINS; GLYCOSIDE HYDROLASES; HUMANS; MICROSCOPY, ELECTRON, SCANNING; POLYSACCHARIDES; RESPIRATORY SYNCYTIAL VIRUS, HUMAN; VIRAL PROTEINS;

RESPIRATORY SYNCYTIAL VIRUS; RICE STRIPE VIRUS;

EID: 33745473970     PISSN: 00426822     EISSN: 10960341     Source Type: Journal    
DOI: 10.1016/j.virol.2006.01.023     Document Type: Article

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