Teratology study of derivatives of tetramethylcyclopropyl amide analogues of valproic acid in mice

Birth Defects Research Part B - Developmental and Reproductive Toxicology

Volumn 77, Issue 3, 2006, Pages 227-233

  Okada, Akinobu ^a   Onishi, Yuko ^a   Aoki, Yoshinobu ^a   Yagen, Boris ^b   Sobol, Eyal ^b   Bialer, Meir ^b   Fujiwara, Michio ^a  

^a ASTELLAS PHARMA INC   (Japan)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Double staining; N methoxy TMCD; Neural tube defects; NMRI mouse; Skeletal malformations; Teratogen; TMC urea; Valproic acid

Indexed keywords

2,2,3,3 TETRAMETHYLCYCLOPROPANECARBONYL UREA; AMIDE; N METHOXY 2,2,3,3 TETRAMETHYCYCLOPROPANECARBOXAMIDE; TETRAMETHYLCYCLOPROPYL AMIDE DERIVATIVE; UNCLASSIFIED DRUG; UREA DERIVATIVE; VALPROIC ACID; VALPROIC ACID DERIVATIVE;

ADOLESCENT; ANIMAL TISSUE; ANTICONVULSANT ACTIVITY; ARTICLE; BONE; CARTILAGE; CESAREAN SECTION; CONTROLLED STUDY; DOUBLE STAINING; DRUG STRUCTURE; FETUS; FETUS MALFORMATION; FETUS WASTAGE; MOUSE; MOUSE STRAIN; NEURAL TUBE DEFECT; NMRI MOUSE; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; SKELETON MALFORMATION; SPINE MALFORMATION; STAINING; TERATOLOGY;

ABNORMALITIES, DRUG-INDUCED; AMIDES; ANIMALS; BODY WEIGHT; CESAREAN SECTION; CYCLOPROPANES; FEMALE; FETUS; MICE; PREGNANCY; SKELETON; TERATOLOGY; UREA; VALPROIC ACID;

ANIMALIA;

EID: 33745460470     PISSN: 15429733     EISSN: None     Source Type: Journal    
DOI: 10.1002/bdrb.20078     Document Type: Article

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