The TGFβ1 gene codon 10 polymorphism contributes to the genetic predisposition to high myopia

Molecular Vision

Volumn 12, Issue , 2006, Pages 698-703

  Lin, Hui Ju ^a,b   Wan, Lei ^a   Tsai, Yuhsin ^a   Tsai, Yi Yu ^a   Fan, Seng Sheen ^b   Tsai, Chang Hai ^a   Tsai, Fuu Jen ^a  

^a CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^b TUNGHAI UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; TRANSFORMING GROWTH FACTOR BETA1; TGFB1 PROTEIN, HUMAN; TRANSFORMING GROWTH FACTOR BETA;

ADOLESCENT; ADULT; ARTICLE; CASE CONTROL STUDY; CHINESE; CODON; CONTROLLED STUDY; GENE EXPRESSION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE; HIGH MYOPIA; HIGH RISK PATIENT; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; PATHOPHYSIOLOGY; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROBABILITY; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SCLERA; TAIWAN; ASIAN; GENETICS; HOMOZYGOTE; HOSPITALIZATION; MYOPIA;

ADOLESCENT; ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CODON; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HOMOZYGOTE; HUMANS; MYOPIA; POLYMORPHISM, GENETIC; SEVERITY OF ILLNESS INDEX; TAIWAN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 33745317436     PISSN: 10900535     EISSN: 10900535     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Chow YC, Dhillon B, Chew PT, Chew SJ. Refractive errors in Singapore medical students. Singapore Med J 1990; 31:472-3.
2. Vongphanit J, Mitchell P, Wang JJ. Prevalence and progression of myopic retinopathy in an older population. Ophthalmology 2002; 109:704-11.
3. Feldkamper M, Schaeffel F. Interactions of genes and environment in myopia. Dev Ophthalmol 2003; 37:34-49.
4. Lyhne N, Sjolie AK, Kyvik KO, Green A. The importance of genes and environment for ocular refraction and its determiners: a population based study among 20-45 year old twins. Br J Ophthalmol 2001; 85:1470-6.
5. Hammond CJ, Snieder H, Gilbert CE, Spector TD. Genes and environment in refractive error: the twin eye study. Invest Ophthalmol Vis Sci 2001; 42:1232-6.
6. Celorio JM, Pruett RC. Prevalence of lattice degeneration and its relation to axial length in severe myopia. Am J Ophthalmol 1991; 111:20-3.
7. Chiang LM, Ho TC, Lin LLK, Yang CM, Liu KR, Chen MS. Prevalence of retinal detachment and peripheral retinal degeneration in high myopia college students in Taiwan. Invest Ophthalmol Vis Sci 1993; 34:S937.
8. Curtin BJ, Teng CC. Scleral changes in pathological myopia. Trans Am Acad Ophthalmol Otolaryngol 1958; 62:777-88; discussion788-90.
9. Curtin BJ, Iwamoto T, Renaldo DP. Normal and staphylomatous sclera of high myopia. An electron microscopic study. Arch Ophthalmol 1979; 97:912-5.
10. Rohrer B, Stell WK. Basic fibroblast growth factor (bFGF) and transforming growth factor beta (TGF-beta) act as stop and go signals to modulate postnatal ocular growth in the chick. Exp Eye Res 1994; 58:553-61.
11. Shah M, Foreman DM, Ferguson MW. Neutralisation of TGF-beta 1 and TGF-beta 2 or exogenous addition of TGF-beta 3 to cutaneous rat wounds reduces scarring. J Cell Sci 1995; 108:985-1002.
12. Guggenheim JA, McBrien NA. Form-deprivation myopia induces activation of scleral matrix metalloproteinase-2 in tree shrew. Invest Ophthalmol Vis Sci 1996; 37:1380-95.
13. Honda S, Fujii S, Sekiya Y, Yamamoto M. Retinal control on the axial length mediated by transforming growth factor-beta in chick eye. Invest Ophthalmol Vis Sci 1996; 37:2519-26.
14. Rada JA, Thoft RA, Hassell JR. Increased aggrecan (cartilage proteoglycan) production in the sclera of myopic chicks. Dev Biol 1991; 147:303-12.
15. Seko Y, Tanaka Y, Tokoro T. Influence of bFGF as a potent growth stimulator and TGF-beta as a growth regulator on scleral chondrocytes and scleral fibroblasts in vitro. Ophthalmic Res 1995; 27:144-52.
16. Gentle A, McBrien NA. Retinoscleral control of scleral remodelling in refractive development: a role for endogenous FGF-2? Cytokine 2002; 18:344-8.
17. McBrien NA, Lawlor P, Gentle A. Scleral remodeling during the development of and recovery from axial myopia in the tree shrew. Invest Ophthalmol Vis Sci 2000; 41:3713-9.
18. Jobling AI, Nguyen M, Gentle A, McBrien NA. Isoform-specific changes in scleral transforming growth factor-beta expression and the regulation of collagen synthesis during myopia progression. J Biol Chem 2004; 279:18121-6.
19. Patel A, Scott WR, Lympany PA, Rippin JD, Gill GV, Barnett AH, Bain SC, Warren 3/UK GoKind Study Group. The TGF-beta 1 gene codon 10 polymorphism contributes to the genetic predisposition to nephropathy in Type 1 diabetes. Diabet Med 2005; 22:69-73.
20. Rivera MA, Echegaray M, Rankinen T, Perusse L, Rice T, Gagnon J, Leon AS, Skinner JS, Wilmore JH, Rao DC, Bouchard C. TGF-beta(1) gene-race interactions for resting and exercise blood pressure in the HERITAGE Family Study. J Appl Physiol 2001; 91:1808-13.
21. Zhou X, Tan FK, Stivers DN, Arnett FC. Microsatellites and intragenic polymorphisms of transforming growth factor beta and platelet-derived growth factor and their receptor genes in Native Americans with systemic sclerosis (scleroderma): a preliminary analysis showing no genetic association. Arthritis Rheum 2000; 43:1068-73.
22. Ziv E, Cauley J, Morin PA, Saiz R, Browner WS. Association between the T29->C polymorphism in the transforming growth factor beta1 gene and breast cancer among elderly white women: The Study of Osteoporotic Fractures. JAMA 2001; 285:2859-63. Erratum in: JAMA 2001; 286:3081.
23. Holweg CT, Baan CC, Balk AH, Niesters HG, Maat AP, Mulder PM, Weimar W. The transforming growth factor-beta1 codon 10 gene polymorphism and accelerated graft vascular disease after clinical heart transplantation. Transplantation 2001; 71:1463-7.
24. Holgate ST, Lackie PM, Howarth PH, Roche WR, Puddicombe SM, Richter A, Wilson SJ, Holloway JW, Davies DE. Invited lecture: activation of the epithelial mesenchymal trophic unit in the pathogenesis of asthma. Int Arch Allergy Immunol 2001; 124:253-8.
25. Teikari J, O'Donnell JJ, Kaprio J, Koskenvuo M. Genetic and environmental effects on oculometric traits. Optom Vis Sci 1989; 66:594-9.
26. Young TL, Ronan SM, Alvear AB, Wildenberg SC, Oetting WS, Atwood LD, Wilkin DJ, King RA. A second locus for familial high myopia maps to chromosome 12q. Am J Hum Genet 1998; 63:1419-24.
27. Farbrother JE, Kirov G, Owen MJ, Pong-Wong R, Haley CS, Guggenheim JA. Linkage analysis of the genetic loci for high myopia on 18p, 12q, and 17q in 51 U.K. families. Invest Ophthalmol Vis Sci 2004; 45:2879-85.
28. Paluru P, Ronan SM, Heon E, Devoto M, Wildenberg SC, Scavello G, Holleschau A, Makitie O, Cole WG, King RA, Young TL. New locus for autosomal dominant high myopia maps to the long arm of chromosome 17. Invest Ophthalmol Vis Sci 2003; 44:1830-6.
29. Strachan T, Read AP. Genes in pedigrees. In: Strachan T, Read AP, editors. Human molecular genetics. 2nd ed. New York: John Wiley & Sons Inc.; 1999. p. 65-66.
30. Passarge E. Color atlas of genetics. 2nd ed. New York: Thieme; 2001.
31. Carturan S, Roccatello D, Menegatti E, Di Simone D, Davit A, Piazza A, Sena LM, Matullo G. Association between transforming growth factor beta1 gene polymorphisms and IgA nephropathy. J Nephrol 2004; 17:786-93.
32. Kaczur V, Takacs M, Szalai C, Falus A, Nagy Z, Berencsi G, Balazs C. Analysis of the genetic variability of the 1st (CCC/ ACC, P52T) and the 10th exons (bp 1012-1704) of the TSH receptor gene in Graves' disease. Eur J Immunogenet 2000; 27:17-23.
33. Vinkanharju A, Melkko T, Risteli J, Risteli L. New PCR-based method for the Sp1 site polymorphism in the COL1A1 gene. Clin Chem Lab Med 2001; 39:624-6.
34. Karadayi K, Akin T, Ciftci F, Top C, Keskin O, Kardesoglu E, Bilge AH. The association between hypermetropia and essential hypertension. Am J Ophthalmol 2005; 140:446-453.
35. Kusakari T, Sato T, Tokoro T. Visual deprivation stimulates the exchange of the fibrous sclera into the cartilaginous sclera in chicks. Exp Eye Res 2001; 73:533-46.
36. Lam DS, Lee WS, Leung YF, Tam PO, Fan DS, Fan BJ, Pang CP. TGFbeta-induced factor: a candidate gene for high myopia. Invest Ophthalmol Vis Sci 2003; 44:1012-5.