New PCR-based method for the Sp1 site polymorphism in the COL1A1 gene

Clinical Chemistry and Laboratory Medicine

Volumn 39, Issue 7, 2001, Pages 624-626

  Vinkanharju, A ^a   Melkko, T ^a   Risteli, J ^a   Risteli, L ^a  

^a UNIVERSITY OF OULU   (Finland)

Author keywords

COL1A1 gene; Gene polymorphism; PCR

Indexed keywords

COLLAGEN TYPE 1; OLIGONUCLEOTIDE; PRIMER DNA; RESTRICTION ENDONUCLEASE;

ALLELE; ANALYTIC METHOD; ARTICLE; BASE MISPAIRING; BASE PAIRING; BINDING SITE; CONTROLLED STUDY; EUROPE; FEMALE; FINLAND; GENE AMPLIFICATION; GENE FREQUENCY; GENE SEQUENCE; GENETIC POLYMORPHISM; HETEROZYGOSITY; HUMAN; HUMAN EXPERIMENT; HUMAN TISSUE; INTRON; MALE; MOLECULAR RECOGNITION; NORMAL HUMAN; OSTEOPOROSIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; RISK ASSESSMENT;

ALLELES; COLLAGEN; COLLAGEN TYPE I; DNA PRIMERS; FEMALE; GENOTYPE; HUMANS; MALE; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; SP1 TRANSCRIPTION FACTOR;

EID: 0034897666     PISSN: 14346621     EISSN: None     Source Type: Journal    
DOI: 10.1515/CCLM.2001.100     Document Type: Article

References (8)

1. Reduced bone density and osteoporosis associated with a polymorphic Sp1 binding site in the collagen type I α1 gene
2. Collagen Ia1 Sp1 polymorphism, bone mass, and bone turnover in healthy French premenopausal women: The OFELY study
3. An Sp1 binding site polymorphism in the COL1A1 gene predicts osteoporotic fractures in both men and women
4. Relation of alleles of the collagen type Iα1 gene to bone density and the risk of osteoporotic fractures in postmenopausal women
5. Collagen type I α1 gene Sp1 polymorphism in premenopausal women with primary osteoporosis: Improved detection of Sp1 binding site polymorphism in the collagen type 1 gene
6. Collagen type I alpha 1 gene polymorphism in idiopathic osteoporosis in men
7. COLIA1 polymorphism contributes to bone mineral density to assess prevalent wrist fractures
8. COL1A 1 SP1 polymorphism and bone mass in elderly women