Mutagenesis and molecular modeling reveal the importance of the 5-HT 3 receptor F-loop

Journal of Biological Chemistry

Volumn 281, Issue 24, 2006, Pages 16576-16582

  Thompson, Andrew J ^a   Padgett, Claire L ^a   Lummis, Sarah C R ^a,b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; CELLS; CHEMICAL BONDS; GENETIC ENGINEERING; MOLECULAR BIOLOGY; MOLECULAR STRUCTURE;

AMINO ACID LOOPS; BINDING AFFINITY; HEK293 CELLS; MOLECULAR MODELING;

MUTAGENESIS;

ACETYLCHOLINE; ALANINE; ARGININE; ASPARTIC ACID; BINDING PROTEIN; CYSTEINE; GLYCINE; SERINE; SEROTONIN 3 RECEPTOR; VALINE;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CRYSTAL STRUCTURE; EMBRYO; GENE MUTATION; HUMAN; HUMAN CELL; HUMAN TISSUE; LIGAND BINDING; MOLECULAR MODEL; MOUSE; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN VARIANT; RAT; SEQUENCE HOMOLOGY;

ALANINE; AMINO ACID SEQUENCE; CARBON; CELL LINE; HUMANS; KINETICS; MICROSCOPY, CONFOCAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; MUTATION; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, SEROTONIN, 5-HT3; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 33745224113     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M601265200     Document Type: Article

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