Effect of osmolality on net fluid absorption in non-infected and ETEC-infected piglet small intestinal segments

Research in Veterinary Science

Volumn 81, Issue 2, 2006, Pages 274-279

  Kiers, J L ^a   Hoogendoorn, A ^a   Nout, R M J ^a   Rombouts, F M ^a   Nabuurs, M J A ^a   van der Meulen, J ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Diarrhoea; Osmolality; Pig; Rehydration; Weaning

Indexed keywords

GLUCOSE; MANNITOL; ORAL REHYDRATION SOLUTION; SODIUM CHLORIDE; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; ELECTROLYTE DISTURBANCE; ENTEROTOXIGENIC ESCHERICHIA COLI; INFECTIOUS DIARRHEA; INTESTINE PERFUSION; NONHUMAN; OSMOLALITY; SMALL INTESTINE ABSORPTION; STATISTICAL ANALYSIS; STATISTICAL SIGNIFICANCE; SWINE DISEASE; WATER LOSS;

ANIMALS; DIARRHEA; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; INTESTINAL ABSORPTION; INTESTINAL DISEASES; INTESTINE, SMALL; MANNITOL; OSMOLAR CONCENTRATION; PERFUSION; SODIUM CHLORIDE; SWINE; SWINE DISEASES;

ESCHERICHIA COLI;

EID: 33745223536     PISSN: 00345288     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.rvsc.2005.12.007     Document Type: Article

References (19)

1. Bhan M.K. Current and future management of childhood diarrhoea. International Journal of Antimicrobial Agents 14 (2000) 71-73
2. Cunha Ferreira R.M., Elliott E.J., Watson A.J., Brennan E., Walker-Smith J.A., and Farthing M.J. Dominant role for osmolality in the efficacy of glucose and glycine-containing oral rehydration solutions: studies in a rat model of secretory diarrhoea. Acta Paediatrica 81 (1992) 46-50
3. Fairbrother J.M., Nadeau E., and Gyles C.L. Escherichia coli in postweaning diarrhea in pigs: an update on bacterial types, pathogenesis, and prevention strategies. Animal Health Research Reviews 6 (2005) 17-39
4. Farthing M.J. Studies of oral rehydration solutions in animal models. Clinical Therapeutics 12 Suppl. A (1990) 51-62
5. GraphPad, 2004. GraphPad Prism version 4.00 for Windows. GraphPad Software, San Diego, California USA. Available from: .
6. Hampson D.J. Postweaning Escherichia coli diarrhoea in pigs. In: Gyles C.J. (Ed). Escherichia coli in Domestic Animals and Humans (1994), CAB International, Wallingford, UK 171-191
7. Hunt J.B., Elliott E.J., Fairclough P.D., Clark M.L., and Farthing M.J. Water and solute absorption from hypotonic glucose-electrolyte solutions in human jejunum. Gut 33 (1992) 479-483
8. Hunt J.B., Thillainayagam A.V., Carnaby S., Fairclough P.D., Clark M.L., and Farthing M.J. Absorption of a hypotonic oral rehydration solution in a human model of cholera. Gut 35 (1994) 211-214
9. Nabuurs M.J., Hoogendoorn A., van Zijderveld F.G., and van der Klis J.D. A long-term perfusion test to measure net absorption in the small intestine of weaned pigs. Research in Veterinary Science 55 (1993) 108-114
10. Nagy B., and Fekete P.Z. Enterotoxigenic Escherichia coli (ETEC) in farm animals. Veterinary Research 30 (1999) 259-284
11. Nalin D.R., Hirschhorn N., Greenough W., Fuchs G.J., and Cash R.A. Clinical concerns about reduced-osmolarity oral rehydration solution. Journal of the American Medical Association 291 (2004) 2632-2635
12. Owusu-Asiedu A., Nyachoti C.M., and Marquardt R.R. Response of early-weaned pigs to an enterotoxigenic Escherichia coli (K88) challenge when fed diets containing spray-dried porcine plasma or pea protein isolate plus egg yolk antibody, zinc oxide, fumaric acid, or antibiotic. Journal of Animal Science 81 (2003) 1790-1798
13. Pillai G.V., Brueton M.J., Burston D., and Sandhu B.K. Evaluation of the effects of varying solute content on the efficacy of oral rehydration solutions in a rat model of secretory diarrhoea. Journal of Pediatric Gastroenterology and Nutrition 18 (1994) 457-460
14. Sellwood R., Gibbons R.A., Jones G.W., and Rutter J.M. Adhesion of enteropathogenic Escherichia coli to pig intestinal brush borders: the existence of two pig phenotypes. Journal of Medical Microbiology 8 (1975) 405-411
15. Soergel K.H., Whalen G.E., and Harris J.A. Passive movement of water and sodium across the human small intestinal mucosa. Journal of Applied Physiology 24 (1968) 40-48
16. Thillainayagam A.V., Carnaby S., Dias J.A., Clark M.L., and Farthing M.J. Evidence of a dominant role for low osmolality in the efficacy of cereal based oral rehydration solutions: studies in a model of secretory diarrhoea. Gut 34 (1993) 920-925
17. Thillainayagam A.V., Hunt J.B., and Farthing M.J. Enhancing clinical efficacy of oral rehydration therapy: is low osmolality the key?. Gastroenterology 114 (1998) 197-210
18. van Beers-Schreurs H.M.G., and Bruininx E.M.A.M. Nutritional management to prevent disorders in post-weaning pig health. In: Blok M.C., Vahl H.A., de Lange L., van de Braak A.E., Hemke G., and Hessing M. (Eds). Nutrition and Health of the Gastrointestinal Tract (2002), Wageningen Academic Publishers, The Netherlands, Wageningen 135-158
19. Wall C.R., Bates M.S., Cleghorn C.J., and Ward L. Studies of water and electrolyte movement for oral rehydration solutions (rice- and glucose-based) across a normal and secreting gut using a dual isotope tracer technique in a rat perfusion model. Alimentary Pharmacology and Therapeutics 11 (1997) 581-587