메뉴 건너뛰기




Volumn 6, Issue 3, 2006, Pages 277-301

The history of the HSV amplicon: From naturally occurring defective genomes to engineered amplicon vectors

Author keywords

Amplicon; Cleavage packaging; Concatemer; Foreign gene; Helper virus; Origin; oriL; oriS; Pac 1; Pac 2; Rolling circle; Transgene

Indexed keywords

BETA GALACTOSIDASE; CIS ACTING ELEMENT; OVALBUMIN; PROTEIN P53; VIRUS DNA; VIRUS VECTOR;

EID: 33745215409     PISSN: 15665232     EISSN: None     Source Type: Journal    
DOI: 10.2174/156652306777591992     Document Type: Review
Times cited : (15)

References (94)
  • 1
    • 26444460204 scopus 로고    scopus 로고
    • Site-directed mutagenesis of large DNA palindromes: Construction and in. vitro characterization of herpes simplex virus type 1 mutants containing point mutations that eliminate the oriL or oriS initiation function
    • Balliet, J. W., Min, J. C., Cabatingan, M. S., and Schaffer, P. A. (2005). Site-directed mutagenesis of large DNA palindromes: construction and in. vitro characterization of herpes simplex virus type 1 mutants containing point mutations that eliminate the oriL or oriS initiation function. J. Virol. 79(20), 12783-97.
    • (2005) J. Virol. , vol.79 , Issue.20 , pp. 12783-12797
    • Balliet, J.W.1    Min, J.C.2    Cabatingan, M.S.3    Schaffer, P.A.4
  • 2
    • 33645957647 scopus 로고    scopus 로고
    • Point mutations in herpes simplex virus type 1 oriL, but not in oriS, reduce pathogenesis during acute infection of mice and impair reactivation from latency
    • Balliet, J. W., and Schaffer, P. A. (2006). Point mutations in herpes simplex virus type 1 oriL, but not in oriS, reduce pathogenesis during acute infection of mice and impair reactivation from latency. J. Virol. 80(1), 440-50.
    • (2006) J. Virol. , vol.80 , Issue.1 , pp. 440-450
    • Balliet, J.W.1    Schaffer, P.A.2
  • 4
    • 33645980953 scopus 로고    scopus 로고
    • The herpes simplex virus type 1 vhs-UL41 gene secuRes. viral replication by temporarily evading apoptotic cellular Res.ponse to infection: Vhs-UL41 activity might require interactions with elements of cellular mRNA degradation machinery
    • Barzilai, A., Zivony-Elbom, I., Sarid, R., Noah, E., and Frenkel, N. (2006). The herpes simplex virus type 1 vhs-UL41 gene secuRes. viral replication by temporarily evading apoptotic cellular Res.ponse to infection: Vhs-UL41 activity might require interactions with elements of cellular mRNA degradation machinery. J. Virol. 80(1), 505-13.
    • (2006) J. Virol. , vol.80 , Issue.1 , pp. 505-513
    • Barzilai, A.1    Zivony-Elbom, I.2    Sarid, R.3    Noah, E.4    Frenkel, N.5
  • 5
    • 0017714305 scopus 로고
    • Replication of herpesvirus DNA. II. Sedimentation characteristics of newly synthesized DNA
    • Ben-Porat, T., and Tokazewski, S. A. (1977). Replication of herpesvirus DNA. II. Sedimentation characteristics of newly synthesized DNA. Virology 79(2), 292-301.
    • (1977) Virology , vol.79 , Issue.2 , pp. 292-301
    • Ben-Porat, T.1    Tokazewski, S.A.2
  • 6
    • 0020082716 scopus 로고
    • Territorial limits and functional anatomy of the simian-virus 40 replication origin
    • Bergsma, D. J., Olive, D. M., Hartzell, S. W., and Subramanian, K. N. (1982). Territorial limits and functional anatomy of the simian-virus 40 replication origin. In "Proc Natl Acad Sci USA", Vol. 79, pp. 381-5.
    • (1982) "Proc Natl Acad Sci USA" , vol.79 , pp. 381-385
    • Bergsma, D.J.1    Olive, D.M.2    Hartzell, S.W.3    Subramanian, K.N.4
  • 7
    • 4644300204 scopus 로고    scopus 로고
    • Use of amplicon-6 vectors derived from human herpesvirus 6 for efficient expRes.sion of membrane-associated and -secreted proteins in T cells
    • Borenstein, R., Singer, O., Moseri, A., and Frenkel, N. (2004). Use of amplicon-6 vectors derived from human herpesvirus 6 for efficient expRes.sion of membrane-associated and -secreted proteins in T cells. J. Virol. 78(9), 4730-43.
    • (2004) J. Virol. , vol.78 , Issue.9 , pp. 4730-4743
    • Borenstein, R.1    Singer, O.2    Moseri, A.3    Frenkel, N.4
  • 8
    • 0033140039 scopus 로고    scopus 로고
    • Replication-competent herpes simplex virus vector G207 and cisplatin combination therapy for head and neck squamous cell carcinoma
    • Chahlavi, A., Todo, T., Martuza, R. L., and Rabkin, S. D. (1999). Replication-competent herpes simplex virus vector G207 and cisplatin combination therapy for head and neck squamous cell carcinoma. Neoplasia 1(2), 162-9.
    • (1999) Neoplasia , vol.1 , Issue.2 , pp. 162-169
    • Chahlavi, A.1    Todo, T.2    Martuza, R.L.3    Rabkin, S.D.4
  • 9
    • 0022919477 scopus 로고
    • A method for identifying the viral genes required for herpesvirus DNA replication
    • Challberg, M. D. (1986). A method for identifying the viral genes required for herpesvirus DNA replication. Proc. Natl. Acad. Sci. USA 83(23), 9094-8.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , Issue.23 , pp. 9094-9098
    • Challberg, M.D.1
  • 10
    • 0021955725 scopus 로고
    • Isomerization of herpes simplex virus 1 genome: Identification of the cis-acting and recombination sites within the domain of the a sequence
    • Chou, J., and Roizman, B. (1985). Isomerization of herpes simplex virus 1 genome: identification of the cis-acting and recombination sites within the domain of the a sequence. Cell 41(3), 803-11.
    • (1985) Cell , vol.41 , Issue.3 , pp. 803-811
    • Chou, J.1    Roizman, B.2
  • 11
    • 0017111179 scopus 로고
    • Analysis of herpesvirus DNA substructure by means of Res.triction endonucleases
    • Clements, J. B., Cortini, R., and Wilkie, N. M. (1976). Analysis of herpesvirus DNA substructure by means of Res.triction endonucleases. J. Gen. Virol. 30(2), 243-56.
    • (1976) J. Gen. Virol. , vol.30 , Issue.2 , pp. 243-256
    • Clements, J.B.1    Cortini, R.2    Wilkie, N.M.3
  • 12
    • 0028221821 scopus 로고
    • Cellular protein interactions with herpes simplex virus type 1 oriS
    • Dabrowski, C. E., Carmillo, P. J., and Schaffer, P. A. (1994). Cellular protein interactions with herpes simplex virus type 1 oriS. Mol. Cell. Biol 14(4), 2545-55.
    • (1994) Mol. Cell. Biol , vol.14 , Issue.4 , pp. 2545-2555
    • Dabrowski, C.E.1    Carmillo, P.J.2    Schaffer, P.A.3
  • 13
    • 0025939360 scopus 로고
    • Herpes simplex virus type 1 origin-specific binding protein: OriS-binding properties and effects of cellular proteins
    • Dabrowski, C. E., and Schaffer, P. A. (1991). Herpes simplex virus type 1 origin-specific binding protein: oriS-binding properties and effects of cellular proteins. J. Virol. 65(6), 3140-50.
    • (1991) J. Virol. , vol.65 , Issue.6 , pp. 3140-3150
    • Dabrowski, C.E.1    Schaffer, P.A.2
  • 14
    • 33645874763 scopus 로고    scopus 로고
    • Oncolytic Viruses Derived from the gamma34.5-Deleted Herpes Simplex Virus Recombinant R3616 Encode a Truncated UL3 Protein
    • Dambach, M. J., Trecki, J., Martin, N., and Markovitz, N. S. (2006). Oncolytic Viruses Derived from the gamma34.5-Deleted Herpes Simplex Virus Recombinant R3616 Encode a Truncated UL3 Protein. Mol. Ther 13(5), 891-8.
    • (2006) Mol. Ther , vol.13 , Issue.5 , pp. 891-898
    • Dambach, M.J.1    Trecki, J.2    Martin, N.3    Markovitz, N.S.4
  • 15
    • 0021723832 scopus 로고
    • Structure of the genome termini of varicella-zoster virus
    • Davison, A. J. (1984). Structure of the genome termini of varicella-zoster virus. J. Gen. Virol. 65 (Pt11), 1969-77.
    • (1984) J. Gen. Virol. , vol.65 , Issue.PART 11 , pp. 1969-1977
    • Davison, A.J.1
  • 16
    • 0019842340 scopus 로고
    • Nucleotide sequences of the joint between the L and S segments of herpes simplex virus types 1 and 2
    • Davison, A. J., and Wilkie, N. M. (1981). Nucleotide sequences of the joint between the L and S segments of herpes simplex virus types 1 and 2. J. Gen. Virol. 55(Pt 2), 315-31.
    • (1981) J. Gen. Virol. , vol.55 , Issue.PART 2 , pp. 315-331
    • Davison, A.J.1    Wilkie, N.M.2
  • 17
    • 0024588675 scopus 로고
    • Analysis of Ori-S sequence of HSV-1: Identification of one functional DNA binding domain
    • Deb, S., and Deb, S. P. (1989). Analysis of Ori-S sequence of HSV-1: identification of one functional DNA binding domain. Nucleic Acids. Res. 17(7), 2733-52.
    • (1989) Nucleic Acids. Res. , vol.17 , Issue.7 , pp. 2733-2752
    • Deb, S.1    Deb, S.P.2
  • 18
    • 0022521898 scopus 로고
    • Functional domains within the a sequence involved in the cleavage-packaging of herpes simplex virus DNA
    • Deiss, L. P., Chou, J., and Frenkel, N. (1986). Functional domains within the a sequence involved in the cleavage-packaging of herpes simplex virus DNA. J. Virol. 59(3), 605-18.
    • (1986) J. Virol. , vol.59 , Issue.3 , pp. 605-618
    • Deiss, L.P.1    Chou, J.2    Frenkel, N.3
  • 19
    • 0022636662 scopus 로고
    • Herpes simplex virus amplicon: Cleavage of concatemeric DNA is linked to packaging and involves amplification of the terminally reiterated a sequence
    • Deiss, L. P., and Frenkel, N. (1986). Herpes simplex virus amplicon: cleavage of concatemeric DNA is linked to packaging and involves amplification of the terminally reiterated a sequence. J. Virol. 57(3), 933-41.
    • (1986) J. Virol. , vol.57 , Issue.3 , pp. 933-941
    • Deiss, L.P.1    Frenkel, N.2
  • 20
    • 0023912490 scopus 로고
    • Interaction of origin binding protein with an origin of replication of herpes simplex virus 1
    • Elias, P., and Lehman, I. R. (1988). Interaction of origin binding protein with an origin of replication of herpes simplex virus 1. Proc. Natl. Acad. Sci. USA 85(9), 2959-63.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , Issue.9 , pp. 2959-2963
    • Elias, P.1    Lehman, I.R.2
  • 21
    • 0029844849 scopus 로고    scopus 로고
    • Helper virus-free transfer of herpes simplex virus type 1 plasmid vectors into neural cells
    • Fraefel, C., Song, S., Lim, F., Lang, P, Yu, L., Wang, Y., Wild, P., and Geller, A. I. (1996). Helper virus-free transfer of herpes simplex virus type 1 plasmid vectors into neural cells. J. Virol. 70(10), 7190-7.
    • (1996) J. Virol. , vol.70 , Issue.10 , pp. 7190-7197
    • Fraefel, C.1    Song, S.2    Lim, F.3    Lang, P.4    Yu, L.5    Wang, Y.6    Wild, P.7    Geller, A.I.8
  • 22
    • 0002634735 scopus 로고
    • "Defective interfering herpes viruses"
    • (W. R. D. A.J. Nahmias, and R.R.Schinazy (ed), Ed.) Elsevier/North Holland Puclishing Co., New York, New York
    • Frenkel, N. (1981). "Defective interfering herpes viruses." The Human Hepesviruses - an interdisciplinary prospective. (W. R. D. A.J. Nahmias, and R.R.Schinazy (ed), Ed.) Elsevier/North Holland Puclishing Co., New York, New York.
    • (1981) The Human Hepesviruses - An Interdisciplinary Prospective
    • Frenkel, N.1
  • 23
    • 0016707164 scopus 로고
    • Anatomy of herpes simplex virus DNA. III. Characterization of defective DNA molecules and biological properties of virus populations containing them
    • Frenkel, N., Jacob, R. J., Honess, R. W., Hayward, G. S., Locker, H., and Roizman, B. (1975). Anatomy of herpes simplex virus DNA. III. Characterization of defective DNA molecules and biological properties of virus populations containing them. J. Virol. 16(1), 153-67.
    • (1975) J. Virol. , vol.16 , Issue.1 , pp. 153-167
    • Frenkel, N.1    Jacob, R.J.2    Honess, R.W.3    Hayward, G.S.4    Locker, H.5    Roizman, B.6
  • 24
    • 0016212734 scopus 로고
    • The host DNA sequences in different populations of serially passaged SV40
    • Frenkel, N., Lavi, S., and Winocour, E. (1974). The host DNA sequences in different populations of serially passaged SV40. Virology 60(1), 9-20.
    • (1974) Virology , vol.60 , Issue.1 , pp. 9-20
    • Frenkel, N.1    Lavi, S.2    Winocour, E.3
  • 25
    • 0017202715 scopus 로고
    • Anatomy of herpes simplex virus DNA. VI. Defective DNA originates from the S component
    • Frenkel, N., Locker, H., Batterson, W., Hayward, G. S., and Roizman, B. (1976). Anatomy of herpes simplex virus DNA. VI. Defective DNA originates from the S component. J. Virol. 20(2), 527-31.
    • (1976) J. Virol. , vol.20 , Issue.2 , pp. 527-531
    • Frenkel, N.1    Locker, H.2    Batterson, W.3    Hayward, G.S.4    Roizman, B.5
  • 26
    • 0019231674 scopus 로고
    • Studies of defective herpes simplex viruses
    • Frenkel, N., Locker, H., and Vlazny, D. A. (1980). Studies of defective herpes simplex viruses. Ann. N. Y. Acad. Sci 354, 347-70.
    • (1980) Ann. N. Y. Acad. Sci , vol.354 , pp. 347-370
    • Frenkel, N.1    Locker, H.2    Vlazny, D.A.3
  • 27
    • 0031104710 scopus 로고    scopus 로고
    • Helper virus-free herpes simplex virus-1 plasmid vectors for gene therapy of Parkinson's disease and other neurological disorders
    • Geller, A. I., Yu, L., Wang, Y., and Fraefel, C. (1997). Helper virus-free herpes simplex virus-1 plasmid vectors for gene therapy of Parkinson's disease and other neurological disorders. Exp. Neurol 144(1), 98-102.
    • (1997) Exp. Neurol , vol.144 , Issue.1 , pp. 98-102
    • Geller, A.I.1    Yu, L.2    Wang, Y.3    Fraefel, C.4
  • 28
    • 0021709892 scopus 로고
    • Sequence of the putative origin of replication in the UL region of herpes simplex virus type 1 ANG DNA
    • Gray, C. P., and Kaerner, H. C. (1984). Sequence of the putative origin of replication in the UL region of herpes simplex virus type 1 ANG DNA. J. Gen. Virol. 65 (Pt 12), 2109-19.
    • (1984) J. Gen. Virol. , vol.65 , Issue.PART 12 , pp. 2109-2119
    • Gray, C.P.1    Kaerner, H.C.2
  • 29
    • 0017741831 scopus 로고
    • Some properties of recombinants between type 1 and type 2 herpes simplex viruses
    • Halliburton, I. W., Randall, R. E., Killington, R. A., and Watson, D. H. (1977). Some properties of recombinants between type 1 and type 2 herpes simplex viruses. J. Gen. Virol. 36(3), 471-84.
    • (1977) J. Gen. Virol. , vol.36 , Issue.3 , pp. 471-484
    • Halliburton, I.W.1    Randall, R.E.2    Killington, R.A.3    Watson, D.H.4
  • 30
    • 0022492538 scopus 로고
    • Short repeats cause heterogeneity at genomic terminus of bovine herpesvirus I
    • Hammerschmidt, W., Ludwig, H., and Buhk, H. J. (1986). Short repeats cause heterogeneity at genomic terminus of bovine herpesvirus I. J. Virol. 58(1), 43-9.
    • (1986) J. Virol. , vol.58 , Issue.1 , pp. 43-49
    • Hammerschmidt, W.1    Ludwig, H.2    Buhk, H.J.3
  • 31
    • 0028795640 scopus 로고
    • Cloning and characterization of herpes simplex virus type 1 oriL: Comparison of replication and protein-DNA complex formation by oriL and oriS
    • Hardwicke, M. A., and Schaffer, P. A. (1995). Cloning and characterization of herpes simplex virus type 1 oriL: comparison of replication and protein-DNA complex formation by oriL and oriS. J. Virol. 69(3), 1377-88.
    • (1995) J. Virol. , vol.69 , Issue.3 , pp. 1377-1388
    • Hardwicke, M.A.1    Schaffer, P.A.2
  • 32
    • 0016746537 scopus 로고
    • Anatomy of herpes simplex virus DNA: Strain differences and heterogeneity in the locations of Res.triction endonuclease cleavage sites
    • Hayward, G. S., Frenkel, N., and Roizman, B. (1975). Anatomy of herpes simplex virus DNA: strain differences and heterogeneity in the locations of Res.triction endonuclease cleavage sites. Proc. Natl. Acad. Sci. USA 72(5), 1768-72.
    • (1975) Proc. Natl. Acad. Sci. USA , vol.72 , Issue.5 , pp. 1768-1772
    • Hayward, G.S.1    Frenkel, N.2    Roizman, B.3
  • 33
    • 0038895222 scopus 로고
    • Anatomy of herpes simplex virus DNA: Evidence for four populations of molecules that differ in the relative orientations of their long and short components
    • Hayward, G. S., Jacob, R. J., Wadsworth, S. C., and Roizman, B. (1975). Anatomy of herpes simplex virus DNA: evidence for four populations of molecules that differ in the relative orientations of their long and short components. Proc. Natl. Acad. Sci. USA 72(11), 4243-7.
    • (1975) Proc. Natl. Acad. Sci. USA , vol.72 , Issue.11 , pp. 4243-4247
    • Hayward, G.S.1    Jacob, R.J.2    Wadsworth, S.C.3    Roizman, B.4
  • 34
    • 0015720722 scopus 로고
    • Proteins specified by herpes simplex virus. XI. Identification and relative molar rates of synthesis of structural and nonstructural herpes virus polypeptides in the infected cell
    • Honess, R. W., and Roizman, B. (1973). Proteins specified by herpes simplex virus. XI. Identification and relative molar rates of synthesis of structural and nonstructural herpes virus polypeptides in the infected cell. J. Virol. 12(6), 1347-65.
    • (1973) J. Virol. , vol.12 , Issue.6 , pp. 1347-1365
    • Honess, R.W.1    Roizman, B.2
  • 35
    • 0342284520 scopus 로고
    • Regulation of herpesvirus macromolecular synthesis: Sequential transition of polypeptide synthesis requiRes. functional viral polypeptides
    • Honess, R. W., and Roizman, B. (1975). Regulation of herpesvirus macromolecular synthesis: sequential transition of polypeptide synthesis requiRes. functional viral polypeptides. Proc. Natl. Acad. Sci. USA 72(4), 1276-80.
    • (1975) Proc. Natl. Acad. Sci. USA , vol.72 , Issue.4 , pp. 1276-1280
    • Honess, R.W.1    Roizman, B.2
  • 36
    • 0034947769 scopus 로고    scopus 로고
    • Origin binding protein-containing protein-DNA complex formation at herpes simplex virus type 1 oriS: Role in oriS-dependent DNA replication
    • Isler, J. A., and Schaffer, P. A. (2001). Origin binding protein-containing protein-DNA complex formation at herpes simplex virus type 1 oriS: role in oriS-dependent DNA replication. J. Virol. 75(15), 6808-16.
    • (2001) J. Virol. , vol.75 , Issue.15 , pp. 6808-6816
    • Isler, J.A.1    Schaffer, P.A.2
  • 37
    • 0017686751 scopus 로고
    • Anatomy of herpes simplex virus DNA VIII. Properties of the replicating DNA
    • Jacob, R. J., and Roizman, B. (1977). Anatomy of herpes simplex virus DNA VIII. Properties of the replicating DNA. J. Virol. 23(2), 394-411.
    • (1977) J. Virol. , vol.23 , Issue.2 , pp. 394-411
    • Jacob, R.J.1    Roizman, B.2
  • 38
    • 0018463508 scopus 로고
    • Origin of two different classes of defective HSV-1 Angelotti DNA
    • Kaerner, H. C., Maichle, I. B., Ott, A., and Schroder, C. H. (1979). Origin of two different classes of defective HSV-1 Angelotti DNA. Nucleic Acids. Res. 6(4), 1467-78.
    • (1979) Nucleic Acids. Res. , vol.6 , Issue.4 , pp. 1467-1478
    • Kaerner, H.C.1    Maichle, I.B.2    Ott, A.3    Schroder, C.H.4
  • 39
    • 0019406588 scopus 로고
    • Amplification of a short nucleotide sequence in the repeat units of defective herpes simplex virus type 1 Angelotti DNA
    • Kaerner, H. C., Ott-Hartmann, A., Schatten, R., Schroder, C. H., and Gray, C. P. (1981). Amplification of a short nucleotide sequence in the repeat units of defective herpes simplex virus type 1 Angelotti DNA. J. Virol. 39(1), 75-81.
    • (1981) J. Virol. , vol.39 , Issue.1 , pp. 75-81
    • Kaerner, H.C.1    Ott-Hartmann, A.2    Schatten, R.3    Schroder, C.H.4    Gray, C.P.5
  • 40
    • 29944447647 scopus 로고    scopus 로고
    • Enhanced therapeutic efficacy of G207 for the treatment of glioma through Musashil promoter retargeting of gamma34.5-mediated virulence
    • Kanai, R., Tomita, H., Shinoda, A., Takahashi, M., Goldman, S., Okano, H., Kawase, T., and Yazaki, T. (2006). Enhanced therapeutic efficacy of G207 for the treatment of glioma through Musashil promoter retargeting of gamma34.5-mediated virulence. Gene. Ther 13(2), 106-16.
    • (2006) Gene. Ther , vol.13 , Issue.2 , pp. 106-116
    • Kanai, R.1    Tomita, H.2    Shinoda, A.3    Takahashi, M.4    Goldman, S.5    Okano, H.6    Kawase, T.7    Yazaki, T.8
  • 41
    • 0014765219 scopus 로고
    • Proteins specified by herpes simplex virus. 3. Viruses differing in their effects on the social behavior of infected cells specify different membrane glycoprotiens
    • Keller, J. M., Spear, P. G., and Roizman, B. (1970). Proteins specified by herpes simplex virus. 3. Viruses differing in their effects on the social behavior of infected cells specify different membrane glycoprotiens. Proc. Natl. Acad. Sci. USA 65(4), 865-71.
    • (1970) Proc. Natl. Acad. Sci. USA , vol.65 , Issue.4 , pp. 865-871
    • Keller, J.M.1    Spear, P.G.2    Roizman, B.3
  • 42
    • 12344314098 scopus 로고    scopus 로고
    • Combination of mutated herpes simpley virus type 1 (G207 virus) with radiation for the treatment of squamous cell carcinoma of the head and neck
    • Kim, S. H., Wong, R. J., Kooby, D. A., Carew, J. F., Adusumilli, P. S., Patel, S. G., Shah, J. P., and Fong, Y. (2005). Combination of mutated herpes simpley virus type 1 (G207 virus) with radiation for the treatment of squamous cell carcinoma of the head and neck. Eur. J. Cancer 41(2), 313-22.
    • (2005) Eur. J. Cancer , vol.41 , Issue.2 , pp. 313-322
    • Kim, S.H.1    Wong, R.J.2    Kooby, D.A.3    Carew, J.F.4    Adusumilli, P.S.5    Patel, S.G.6    Shah, J.P.7    Fong, Y.8
  • 43
    • 0021046603 scopus 로고
    • Herpes simplex virus defective genomes: Structure of HSV-1 ANG defective DNA of class II and encoded polypeptides
    • Knopf, C., Strauss, G., Ott-Hartmann, A., Schatten, R., and Kaerner, H. C. (1983). Herpes simplex virus defective genomes: structure of HSV-1 ANG defective DNA of class II and encoded polypeptides. J. Gen. Virol. 64 (Pt 11), 2455-70.
    • (1983) J. Gen. Virol. , vol.64 , Issue.PART 11 , pp. 2455-2470
    • Knopf, C.1    Strauss, G.2    Ott-Hartmann, A.3    Schatten, R.4    Kaerner, H.C.5
  • 44
    • 0023720930 scopus 로고
    • Characterization of major recognition sequences for a herpes simplex virus type 1 origin-binding protein
    • Koff, A., and Tegtmeyer, P. (1988). Characterization of major recognition sequences for a herpes simplex virus type 1 origin-binding protein. J. Virol. 62(11), 4096-103.
    • (1988) J. Virol. , vol.62 , Issue.11 , pp. 4096-4103
    • Koff, A.1    Tegtmeyer, P.2
  • 45
    • 0002646544 scopus 로고
    • "Biology of herpes simplex virus (HSV) defective viruses and development of the amplicon system"
    • Academic PRes.s, San Diego, Calif
    • Kwong, A., and N. Frenkel (1995). "Biology of herpes simplex virus (HSV) defective viruses and development of the amplicon system." Viral vectors, Gene therapy and neuroscience application. Academic PRes.s, San Diego, Calif, 25-42.
    • (1995) Viral Vectors, Gene Therapy and Neuroscience Application , pp. 25-42
    • Kwong, A.1    Frenkel, N.2
  • 46
    • 0021154330 scopus 로고
    • Herpes simplex virus amplicon: Effect of size on replication of constructed defective genomes containing eucaryotic DNA sequences
    • Kwong, A. D., and Frenkel, N. (1984). Herpes simplex virus amplicon: effect of size on replication of constructed defective genomes containing eucaryotic DNA sequences. J. Virol. 51(3), 595-603.
    • (1984) J. Virol. , vol.51 , Issue.3 , pp. 595-603
    • Kwong, A.D.1    Frenkel, N.2
  • 47
    • 0022321174 scopus 로고
    • The herpes simplex virus amplicon. IV. Efficient expRes.sion of a chimeric chicken ovalbumin gene amplified within defective virus genomes
    • Kwong, A. D., and Frenkel, N. (1985). The herpes simplex virus amplicon. IV. Efficient expRes.sion of a chimeric chicken ovalbumin gene amplified within defective virus genomes. Virology 142(2), 421-5.
    • (1985) Virology , vol.142 , Issue.2 , pp. 421-425
    • Kwong, A.D.1    Frenkel, N.2
  • 48
    • 2642604294 scopus 로고
    • Herpes simplex virus-infected cells contain a function(s) that destabilizes both host and viral mRNAs
    • Kwong, A. D., and Frenkel, N. (1987). Herpes simplex virus-infected cells contain a function(s) that destabilizes both host and viral mRNAs. Proc. Natl. Acad. Sci. USA 84(7), 1926-30.
    • (1987) Proc. Natl. Acad. Sci. USA , vol.84 , Issue.7 , pp. 1926-1930
    • Kwong, A.D.1    Frenkel, N.2
  • 49
    • 0024452271 scopus 로고
    • The herpes simplex virus virion host shutoff function
    • Kwong, A. D., and Frenkel, N. (1989). The herpes simplex virus virion host shutoff function. J. Virol. 63(11), 4834-9.
    • (1989) J. Virol. , vol.63 , Issue.11 , pp. 4834-4839
    • Kwong, A.D.1    Frenkel, N.2
  • 50
    • 0023866418 scopus 로고
    • Herpes simplex virus virion host shutoff function
    • Kwong, A. D., Kruper, J. A., and Frenkel, N. (1988). Herpes simplex virus virion host shutoff function. J. Virol. 62(3), 912-21.
    • (1988) J. Virol. , vol.62 , Issue.3 , pp. 912-921
    • Kwong, A.D.1    Kruper, J.A.2    Frenkel, N.3
  • 51
    • 0018238290 scopus 로고
    • The DNA of serially passaged herpes simplex virus: Organization, origin, and homology to viral RNA
    • IARC. Sci. Publ
    • Locker, H., and Frenkel, N. (1978). The DNA of serially passaged herpes simplex virus: organization, origin, and homology to viral RNA. IARC. Sci. Publ. 24 (Pt 1), 75-85.
    • (1978) , vol.24 , Issue.PART 1 , pp. 75-85
    • Locker, H.1    Frenkel, N.2
  • 52
    • 0018638874 scopus 로고
    • BamI, KpnI, and Sall Res.triction enzyme maps of the DNAs of herpes simplex virus strains Justin and F: Occurrence of heterogeneities in defined regions of the viral DNA
    • Locker, H., and Frenkel, N. (1979a). BamI, KpnI, and Sall Res.triction enzyme maps of the DNAs of herpes simplex virus strains Justin and F: occurrence of heterogeneities in defined regions of the viral DNA. J. Virol. 32(2), 429-41.
    • (1979) J. Virol. , vol.32 , Issue.2 , pp. 429-441
    • Locker, H.1    Frenkel, N.2
  • 53
    • 0018342466 scopus 로고
    • Structure and origin of defective genomes contained in serially passaged herpes simplex virus type 1 (Justin)
    • Locker, H., and Frenkel, N. (1979b). Structure and origin of defective genomes contained in serially passaged herpes simplex virus type 1 (Justin). J. Virol. 29(3), 1065-77.
    • (1979) J. Virol. , vol.29 , Issue.3 , pp. 1065-1077
    • Locker, H.1    Frenkel, N.2
  • 54
    • 0019977286 scopus 로고
    • Structure and expRes.sion of class II defective herpes simplex virus genomes encoding infected cell polypeptide number 8
    • Locker, H., Frenkel, N., and Halliburton, I. (1982). Structure and expRes.sion of class II defective herpes simplex virus genomes encoding infected cell polypeptide number 8. J. Virol. 43(2), 574-93.
    • (1982) J. Virol. , vol.43 , Issue.2 , pp. 574-593
    • Locker, H.1    Frenkel, N.2    Halliburton, I.3
  • 55
    • 0037417785 scopus 로고    scopus 로고
    • Origin-specific unwinding of herpes simplex virus 1 DNA by the viral UL9 and ICP8 proteins: Visualization of a specific preunwinding complex
    • Makhov, A. M., Lee, S. S., Lehman, I. R., and Griffith, J. D. (2003). Origin-specific unwinding of herpes simplex virus 1 DNA by the viral UL9 and ICP8 proteins: visualization of a specific preunwinding complex. Proc. Natl. Acad. Sci. USA 100(3), 898-903.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , Issue.3 , pp. 898-903
    • Makhov, A.M.1    Lee, S.S.2    Lehman, I.R.3    Griffith, J.D.4
  • 57
    • 0021683573 scopus 로고
    • Persistence of the entire Epstein-Barr virus genome integrated into human lymphocyte DNA
    • Matsuo, T., Heller, M., Petti, L., O'Shiro, E., and Kieff, E. (1984). Persistence of the entire Epstein-Barr virus genome integrated into human lymphocyte DNA. Science 226(4680), 1322-5.
    • (1984) Science , vol.226 , Issue.4680 , pp. 1322-1325
    • Matsuo, T.1    Heller, M.2    Petti, L.3    O'Shiro, E.4    Kieff, E.5
  • 59
    • 0021832818 scopus 로고
    • Nucleotide sequence and structural features.Of a novel US-a junction present in a defective herpes simplex virus genome
    • Mocarski, E. S., Deiss, L. P., and Frenkel, N. (1985). Nucleotide sequence and structural featuRes. of a novel US-a junction pRes.ent in a defective herpes simplex virus genome. J. Virol. 55(1), 140-6.
    • (1985) J. Virol. , vol.55 , Issue.1 , pp. 140-146
    • Mocarski, E.S.1    Deiss, L.P.2    Frenkel, N.3
  • 60
    • 0019176944 scopus 로고
    • Molecular engineering of the herpes simplex virus genome: Insertion of a second L-S junction into the genome causes additional genome inversions
    • Mocarski, E. S., Post, L. E., and Roizman, B. (1980). Molecular engineering of the herpes simplex virus genome: insertion of a second L-S junction into the genome causes additional genome inversions. Cell 22(1 Pt 1), 243-55.
    • (1980) Cell , vol.22 , Issue.1 PART 1 , pp. 243-255
    • Mocarski, E.S.1    Post, L.E.2    Roizman, B.3
  • 61
    • 0344150779 scopus 로고
    • Site-specific inversion sequence of the herpes simplex virus genome: Domain and structural featuRes
    • Mocarski, E. S., and Roizman, B. (1981). Site-specific inversion sequence of the herpes simplex virus genome: domain and structural featuRes. Proc. Natl. Acad. Sci. USA 78(11), 7047-51.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , Issue.11 , pp. 7047-7051
    • Mocarski, E.S.1    Roizman, B.2
  • 62
    • 0020444012 scopus 로고
    • Herpesvirus-dependent amplification and inversion of cell-associated viral thymidine kinase gene flanked by viral a sequences and linked to an origin of viral DNA replication
    • Mocarski, E. S., and Roizman, B. (1982a). Herpesvirus-dependent amplification and inversion of cell-associated viral thymidine kinase gene flanked by viral a sequences and linked to an origin of viral DNA replication. Proc. Natl. Acad. Sci. USA 79(18), 5626-30.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , Issue.18 , pp. 5626-5630
    • Mocarski, E.S.1    Roizman, B.2
  • 63
    • 0020399937 scopus 로고
    • Structure and role of the herpes simplex virus DNA termini in inversion, circularization and generation of virion DNA
    • Mocarski, E. S., and Roizman, B. (1982b). Structure and role of the herpes simplex virus DNA termini in inversion, circularization and generation of virion DNA. Cell 31(1), 89-97.
    • (1982) Cell , vol.31 , Issue.1 , pp. 89-97
    • Mocarski, E.S.1    Roizman, B.2
  • 64
    • 0007761340 scopus 로고
    • Herpes simplex virus DNA replication: The UL9 gene encodes an origin-binding protein
    • Olivo, P. D., Nelson, N. J., and Challberg, M. D. (1988). Herpes simplex virus DNA replication: the UL9 gene encodes an origin-binding protein. Proc. Natl. Acad. Sci. USA 85(15), 5414-8.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , Issue.15 , pp. 5414-5418
    • Olivo, P.D.1    Nelson, N.J.2    Challberg, M.D.3
  • 65
    • 0024501059 scopus 로고
    • Herpes simplex virus type 1 gene products required for DNA replication: Identification and overexpRes.sion
    • Olivo, P. D., Nelson, N. J., and Challberg, M. D. (1989). Herpes simplex virus type 1 gene products required for DNA replication: identification and overexpRes.sion. J. Virol. 63(1), 196-204.
    • (1989) J. Virol. , vol.63 , Issue.1 , pp. 196-204
    • Olivo, P.D.1    Nelson, N.J.2    Challberg, M.D.3
  • 66
    • 0021912943 scopus 로고
    • A noninverting genome of a viable herpes simplex virus 1: PRes.ence of head-to-tail linkages in packaged genomes and requirements for circularization after infection
    • Poffenberger, K. L., and Roizman, B. (1985). A noninverting genome of a viable herpes simplex virus 1: pRes.ence of head-to-tail linkages in packaged genomes and requirements for circularization after infection. J. Virol. 53(2), 587-95.
    • (1985) J. Virol. , vol.53 , Issue.2 , pp. 587-595
    • Poffenberger, K.L.1    Roizman, B.2
  • 67
    • 0020526685 scopus 로고
    • Herpes simplex virus mutants defective in the virion-associated shutoff of host polypeptide synthesis and exhibiting abnormal synthesis of alpha (immediate early) viral polypeptides
    • Read, G. S., and Frenkel, N. (1983). Herpes simplex virus mutants defective in the virion-associated shutoff of host polypeptide synthesis and exhibiting abnormal synthesis of alpha (immediate early) viral polypeptides. J. Virol. 46(2), 498-512.
    • (1983) J. Virol. , vol.46 , Issue.2 , pp. 498-512
    • Read, G.S.1    Frenkel, N.2
  • 68
    • 0018393080 scopus 로고
    • The structure and isomerization of herpes simplex virus genomes
    • Roizman, B. (1979). The structure and isomerization of herpes simplex virus genomes. Cell 16(3), 481-94.
    • (1979) Cell , vol.16 , Issue.3 , pp. 481-494
    • Roizman, B.1
  • 69
    • 0001807387 scopus 로고
    • "The family herpesviridae: General description, taxonomy, and classification"
    • (B. Roizman, Ed.), 1 Plenum Publishing Corp., New York
    • Roizman, B. (1982). "The family herpesviridae: general description, taxonomy, and classification." The herpesviruses (B. Roizman, Ed.), 1 Plenum Publishing Corp., New York.
    • (1982) The Herpesviruses
    • Roizman, B.1
  • 70
    • 33745205117 scopus 로고    scopus 로고
    • Fourth Edition ed. "Fields VIROLOGY", Chapter 71, Lippincott - Raven publishers
    • Roizman, P. a. (2002). The Family Herpesviridae: A Brief Introduction, Fourth Edition ed. In "Fields VIROLOGY", Vol. Volume 2, Chapter 71, pp. pg 2221-2228. Lippincott - Raven publishers.
    • (2002) The Family Herpesviridae: A Brief Introduction , vol.2 , pp. 2221-2228
    • Roizman, P.A.1
  • 71
    • 0032798687 scopus 로고    scopus 로고
    • Tamplicon-7, a novel T-lymphotropic vector derived from human herpesvirus 7
    • Romi, H., Singer, O., Rapaport, D., and Frenkel, N. (1999). Tamplicon-7, a novel T-lymphotropic vector derived from human herpesvirus 7. J. Virol. 73(8), 7001-7.
    • (1999) J. Virol. , vol.73 , Issue.8 , pp. 7001-7007
    • Romi, H.1    Singer, O.2    Rapaport, D.3    Frenkel, N.4
  • 72
    • 0017172661 scopus 로고
    • An unusual defective genotype derived from herpes simplex virus strain ANG
    • Schroder, C. H., Stegmann, B., Lauppe, H. F., and Kaerner, H. C. (1975). An unusual defective genotype derived from herpes simplex virus strain ANG. InterVirology 6(4-5), 270-84.
    • (1975) InterVirology , vol.6 , Issue.4-5 , pp. 270-284
    • Schroder, C.H.1    Stegmann, B.2    Lauppe, H.F.3    Kaerner, H.C.4
  • 73
    • 33646040377 scopus 로고    scopus 로고
    • Oncolytic Herpes Viral Therapy is Effective in the Treatment of Hepatocellular Carcinoma Cell Lines
    • Song, T. J., Eisenberg, D. P., Adusumilli, P. S., Hezel, M., and Fong, Y. (2006). Oncolytic Herpes Viral Therapy is Effective in the Treatment of Hepatocellular Carcinoma Cell Lines. J. Gastrointest. Surg 10(4), 532-42.
    • (2006) J. Gastrointest. Surg , vol.10 , Issue.4 , pp. 532-542
    • Song, T.J.1    Eisenberg, D.P.2    Adusumilli, P.S.3    Hezel, M.4    Fong, Y.5
  • 74
    • 0020451027 scopus 로고
    • The herpes simplex virus amplicon: A new eucaryotic defective-virus cloning-amplifying vector
    • Spaete, R. R., and Frenkel, N. (1982). The herpes simplex virus amplicon: a new eucaryotic defective-virus cloning-amplifying vector. Cell 30(1), 295-304.
    • (1982) Cell , vol.30 , Issue.1 , pp. 295-304
    • Spaete, R.R.1    Frenkel, N.2
  • 75
    • 0021991297 scopus 로고
    • The herpes simplex virus amplicon: Analyses of cis-acting replication functions
    • Spaete, R. R., and Frenkel, N. (1985). The herpes simplex virus amplicon: analyses of cis-acting replication functions. Proc. Natl. Acad. Sci. USA 82(3), 694-8.
    • (1985) Proc. Natl. Acad. Sci. USA , vol.82 , Issue.3 , pp. 694-698
    • Spaete, R.R.1    Frenkel, N.2
  • 76
    • 0020338299 scopus 로고
    • Localization of an origin of DNA replication within the TRS/IRS repeated region of the herpes simplex virus type 1 genome
    • Stow, N. D. (1982). Localization of an origin of DNA replication within the TRS/IRS repeated region of the herpes simplex virus type 1 genome. EMBO J. 1(7), 863-7.
    • (1982) EMBO J. , vol.1 , Issue.7 , pp. 863-867
    • Stow, N.D.1
  • 77
    • 0021082753 scopus 로고
    • Characterization of the TRS/IRS origin of DNA replication of herpes simplex virus type 1
    • Stow, N. D., and McMonagle, E. C. (1983). Characterization of the TRS/ IRS origin of DNA replication of herpes simplex virus type 1. Virology 130(2), 427-38.
    • (1983) Virology , vol.130 , Issue.2 , pp. 427-438
    • Stow, N.D.1    McMonagle, E.C.2
  • 78
    • 0023182175 scopus 로고
    • Effects of herpes simplex virus on mRNA stability
    • Strom, T., and Frenkel, N. (1987). Effects of herpes simplex virus on mRNA stability. J. Virol. 61(7), 2198-207.
    • (1987) J. Virol. , vol.61 , Issue.7 , pp. 2198-2207
    • Strom, T.1    Frenkel, N.2
  • 79
    • 0020541955 scopus 로고
    • The double-strand-break repair model for recombination
    • Szostak, J. W., Orr-Weaver, T. L., Rothstein, R. J., and Stahl, F. W. (1983). The double-strand-break repair model for recombination. Cell 33(1), 25-35.
    • (1983) Cell , vol.33 , Issue.1 , pp. 25-35
    • Szostak, J.W.1    Orr-Weaver, T.L.2    Rothstein, R.J.3    Stahl, F.W.4
  • 80
    • 31544468273 scopus 로고    scopus 로고
    • Development of a rapid method to generate multiple oncolytic HSV vectors and their in. vivo evaluation using syngeneic mouse tumor models
    • Terada, K., Wakimoto, H., Tyminski, E., Chiocca, E. A., and Saeki, Y. (2006). Development of a rapid method to generate multiple oncolytic HSV vectors and their in. vivo evaluation using syngeneic mouse tumor models. Gene. Ther 13(8), 705-14.
    • (2006) Gene. Ther , vol.13 , Issue.8 , pp. 705-714
    • Terada, K.1    Wakimoto, H.2    Tyminski, E.3    Chiocca, E.A.4    Saeki, Y.5
  • 81
    • 0036215782 scopus 로고    scopus 로고
    • Immuno-viral therapy of brain tumors by combination of viral therapy with cancer vaccination using a replication-conditional HSV
    • Toda, M., Iizuka, Y., Kawase, T., Uyemura, K., and Kawakami, Y. (2002). Immuno-viral therapy of brain tumors by combination of viral therapy with cancer vaccination using a replication-conditional HSV. Cancer. Gene. Ther 9(4), 356-64.
    • (2002) Cancer. Gene. Ther , vol.9 , Issue.4 , pp. 356-364
    • Toda, M.1    Iizuka, Y.2    Kawase, T.3    Uyemura, K.4    Kawakami, Y.5
  • 82
    • 0033540654 scopus 로고    scopus 로고
    • Herpes simplex. virus as an in situ cancer vaccine for the induction of specific anti-tumor immunity
    • Toda, M., Rabkin, S. D., Kojima, H., and Martuza, R. L. (1999). Herpes simplex. virus as an in situ cancer vaccine for the induction of specific anti-tumor immunity. Hum. Gene. Ther 10(3), 385-93.
    • (1999) Hum. Gene. Ther , vol.10 , Issue.3 , pp. 385-393
    • Toda, M.1    Rabkin, S.D.2    Kojima, H.3    Martuza, R.L.4
  • 83
    • 0033918250 scopus 로고    scopus 로고
    • Evaluation of ganciclovir-mediated enhancement of the antitumoral effect in oncolytic, multimutated herpes simplex virus type 1 (G207) therapy of brain tumors
    • Todo, T., Rabkin, S. D., and Martuza, R. L. (2000). Evaluation of ganciclovir-mediated enhancement of the antitumoral effect in oncolytic, multimutated herpes simplex virus type 1 (G207) therapy of brain tumors. Cancer. Gene. Ther 7(6), 939-46.
    • (2000) Cancer. Gene. Ther , vol.7 , Issue.6 , pp. 939-946
    • Todo, T.1    Rabkin, S.D.2    Martuza, R.L.3
  • 84
    • 0033589694 scopus 로고    scopus 로고
    • Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus
    • Todo, T., Rabkin, S. D., SundaResan, P., Wu, A., Meehan, K. R., Herscowitz, H. B., and Martuza, R. L. (1999). Systemic antitumor immunity in experimental brain tumor therapy using a multimutated, replication-competent herpes simplex virus. Hum. Gene. Ther 10(17), 2741-55.
    • (1999) Hum. Gene. Ther , vol.10 , Issue.17 , pp. 2741-2755
    • Todo, T.1    Rabkin, S.D.2    SundaResan, P.3    Wu, A.4    Meehan, K.R.5    Herscowitz, H.B.6    Martuza, R.L.7
  • 85
    • 0022006793 scopus 로고
    • Signals for site-specific cleavage of HSV DNA: Maturation involves two separate cleavage events at sites distal to the recognition sequences
    • Varmuza, S. L., and Smiley, J. R. (1985). Signals for site-specific cleavage of HSV DNA: maturation involves two separate cleavage events at sites distal to the recognition sequences. Cell 41(3), 793-802.
    • (1985) Cell , vol.41 , Issue.3 , pp. 793-802
    • Varmuza, S.L.1    Smiley, J.R.2
  • 86
    • 0019454926 scopus 로고
    • Replication of herpes simplex virus DNA: Localization of replication recognition signals within defective virus genomes
    • Vlazny, D. A., and Frenkel, N. (1981). Replication of herpes simplex virus DNA: localization of replication recognition signals within defective virus genomes. Proc. Natl. Acad. Sci. USA 79(2), 742-6.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.79 , Issue.2 , pp. 742-746
    • Vlazny, D.A.1    Frenkel, N.2
  • 87
    • 0020327471 scopus 로고
    • Site-specific cleavage/packaging of herpes simplex virus DNA and the selective maturation of nucleocapsids containing full-length viral DNA
    • Vlazny, D. A., Kwong, A., and Frenkel, N. (1982). Site-specific cleavage/ packaging of herpes simplex virus DNA and the selective maturation of nucleocapsids containing full-length viral DNA. Proc. Natl. Acad. Sci. USA 79(5), 1423-7.
    • (1982) Proc. Natl. Acad. Sci. USA , vol.79 , Issue.5 , pp. 1423-1427
    • Vlazny, D.A.1    Kwong, A.2    Frenkel, N.3
  • 88
    • 0012218086 scopus 로고
    • Propagation of the PR8 strain of influenza A virus in chick embryos. III. Properties of the incomplete virus produced in serial passages of undiluted virus
    • von-Magnus (1951a). Propagation of the PR8 strain of influenza A virus in chick embryos. III. Properties of the incomplete virus produced in serial passages of undiluted virus. Acta Pathol Microbiol Scand. 29(2), 157-181.
    • (1951) Acta Pathol Microbiol Scand. , vol.29 , Issue.2 , pp. 157-181
    • von-Magnus1
  • 89
    • 0000493549 scopus 로고
    • Propagation of the PR8 strain of infuenza A virus in chick embryos. II. The formation of incomplete virus following inoculation of large doses of seed virus
    • von-Magnus (1951b). Propagation of the PR8 strain of infuenza A virus in chick embryos. II. The formation of incomplete virus following inoculation of large doses of seed virus. Acta. Pathol. Microbiol. Scand. 28(3).
    • (1951) Acta. Pathol. Microbiol. Scand. , vol.28 , Issue.3
    • von-Magnus1
  • 90
    • 0017290222 scopus 로고
    • Anatomy of herpes simplex virus DNA. V. Terminally repetitive sequences
    • Wadsworth, S., Hayward, G. S., and Roizman, B. (1976). Anatomy of herpes simplex virus DNA. V. Terminally repetitive sequences. J. Virol. 17(2), 503-12.
    • (1976) J. Virol. , vol.17 , Issue.2 , pp. 503-512
    • Wadsworth, S.1    Hayward, G.S.2    Roizman, B.3
  • 91
    • 0024552572 scopus 로고
    • Binding of the herpes simplex virus type 1 UL9 gene product to an origin of viral DNA replication
    • Weir, H. M., Calder, J. M., and Stow, N. D. (1989). Binding of the herpes simplex virus type 1 UL9 gene product to an origin of viral DNA replication. Nucleic Acids. Res. 17(4), 1409-25.
    • (1989) Nucleic Acids. Res. , vol.17 , Issue.4 , pp. 1409-1425
    • Weir, H.M.1    Calder, J.M.2    Stow, N.D.3
  • 92
    • 0025293028 scopus 로고
    • Two binding sites for the herpes simplex virus type 1 UL9 protein are required for efficient activity of the oriS replication origin
    • Weir, H. M., and Stow, N. D. (1990). Two binding sites for the herpes simplex virus type 1 UL9 protein are required for efficient activity of the oriS replication origin. J. Gen. Virol. 71 (Pt 6), 1379-85.
    • (1990) J. Gen. Virol. , vol.71 , Issue.PART 6 , pp. 1379-1385
    • Weir, H.M.1    Stow, N.D.2
  • 93
    • 0021928091 scopus 로고
    • Cloning, sequencing, and functional analysis of oriL, a herpes simplex virus type 1 origin of DNA synthesis
    • Weller, S. K., Spadaro, A., Schaffer, J. E., Murray, A. W., Maxam, A. M., and Schaffer, P. A. (1985). Cloning, sequencing, and functional analysis of oriL, a herpes simplex virus type 1 origin of DNA synthesis. Mol. Cell. Biol 5(5), 930-42.
    • (1985) Mol. Cell. Biol , vol.5 , Issue.5 , pp. 930-942
    • Weller, S.K.1    Spadaro, A.2    Schaffer, J.E.3    Murray, A.W.4    Maxam, A.M.5    Schaffer, P.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.