AMP-activated protein kinase: Function and dysfunction in health and disease

Journal of Physiology

Volumn 574, Issue 1, 2006, Pages 3-6

  Kumar, Prem ^a   Peers, Chris ^b  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; ADIPONECTIN; ANTIDIABETIC AGENT; ANTIOBESITY AGENT; CALCIUM CHANNEL; CANNABINOID; CARNITINE PALMITOYLTRANSFERASE; FATTY ACID SYNTHASE; GHRELIN; GLUCOSE; GLUCOSE TRANSPORTER 4; HEXOKINASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; INSULIN; LEPTIN; LIPID; MAMMALIAN TARGET OF RAPAMYCIN; PHENFORMIN; POTASSIUM CHANNEL; PROTEIN KINASE LKB1; PROTEIN P53;

ATHEROSCLEROSIS; CANCER; CELL METABOLISM; CELL PROLIFERATION; DIET RESTRICTION; DIET THERAPY; DYSLIPIDEMIA; EDITORIAL; ENERGY CONSERVATION; ENZYME ACTIVITY; EXERCISE; FATTY ACID OXIDATION; GLUCOSE TRANSPORT; HUMAN; HYPERTENSION; IMMOBILIZATION; INSULIN RESISTANCE; ISCHEMIC HEART DISEASE; LIFESTYLE; LIVER INJURY; METABOLIC REGULATION; METABOLIC SYNDROME X; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PREVALENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; PULMONARY HYPERTENSION; RISK FACTOR; STROKE; SYMPTOM; UNITED KINGDOM; UNITED STATES; DIABETES MELLITUS; ENERGY BALANCE; ENERGY METABOLISM; ENZYME ACTIVATION; ENZYME DEFECT; ENZYME SUBSTRATE; INCIDENCE; MALIGNANT NEOPLASTIC DISEASE; MORBIDITY; MORTALITY; MUSCLE FUNCTION; PHARMACEUTICAL CARE; PHYSICAL INACTIVITY; PRACTICE GUIDELINE; PROTEIN PROTEIN INTERACTION;

ANIMALS; DIABETES MELLITUS; ENERGY METABOLISM; HUMANS; METABOLIC SYNDROME X; MULTIENZYME COMPLEXES; MUSCLE, SKELETAL; MYOCARDIUM; OBESITY; OXIDATIVE STRESS; OXYGEN; PROTEIN-SERINE-THREONINE KINASES;

EID: 33745210400     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2006.113704     Document Type: Editorial

References (10)

1. Daval M, Foufelle F & FerréP (2006). Functions of AMP-activated protein kinase in adipose tissue. J Physiol 574, 55-62.
2. Dyck JRB & Lopaschuk GD (2006). AMPK alterations in cardiac physiology and pathology: Enemy or ally?J Physiol 574, 95-112.
3. 2 -sensing cells. J Physiol 574, 113-124.
4. Hardie DG, Hawley SA & Scott JW (2006). AMP-activated protein kinase - development of the energy sensor concept. J Physiol 574, 7-15.
5. Jørgensen SB, Richter EA & Wojtaszewski JFP (2006). Role of AMPK in skeletal muscle metabolic regulation and adaptation in relation to exercise. J Physiol 574, 17-31.
6. Motoshima H, Goldstein BJ, Igata M & Araki E (2006). AMPK and cell proliferation - AMPK as a therapeutic target for atherosclerosis and cancer. J Physiol 574, 63-71.
7. Ramamurthy S & Ronnett GV (2006). Developing a head for energy sensing: AMP-activated protein kinase as a multifunctional metabolic sensor in the brain. J Physiol 574, 85-93.
8. Reznick RM & Shulman GI (2006). The role of AMP-activated protein kinase in mitochondrial biogenesis. J Physiol 574, 33-39.
9. Viollet B, Foretz M, Guigas B, Horman S, Dentin R, Bertrand L, Hue L & Andreelli F (2006). Activation of AMP-activated protein kinase in the liver: A new strategy for the management of metabolic hepatic disorders. J Physiol 574, 41-53.
10. Xue B & Kahn BB (2006). AMP-activated protein kinase integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues. J Physiol 574, 73-83.