A haplotype spanning two genes, ELN and LIMK1, decreases their transcripts and confers susceptibility to intracranial aneurysms

Human Molecular Genetics

Volumn 15, Issue 10, 2006, Pages 1722-1734

  Akagawa, Hiroyuki ^a   Tajima, Atsushi ^a   Sakamoto, Yoshiko ^a   Krischek, Boris ^a   Yoneyama, Taku ^a   Kasuya, Hidetoshi ^b   Onda, Hideaki ^b   Hori, Tomokatsu ^b   Kubota, Motoo ^c   Machida, Toshio ^c   Saeki, Naokatsu ^c   Hata, Akira ^c   Hashiguchi, Kazunari ^d   Kimura, Eizou ^d   Kim, Chul Jin ^e   Yang, Tae Ki ^e   Lee, Jong Young ^f   Kimm, Kuchan ^f   Inoue, Ituro ^a,g  

^a UNIVERSITY OF TOKYO   (Japan)

^b TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^c CHIBA UNIVERSITY   (Japan)

^d Kousei General Hospital   (Japan)

^e Chonbuk National University   (South Korea)

^f Korea National Institute of Health   (South Korea)

^g JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN; ELASTIN; LIM DOMAIN KINASE 1; MESSENGER RNA; PHOSPHOTRANSFERASE; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ADULT; AGED; ALLELE; ARTICLE; CONTROLLED STUDY; DEPOLYMERIZATION; EX VIVO STUDY; FEMALE; GENE INSERTION; GENE LOCUS; GENE MAPPING; GENETIC ASSOCIATION; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; INTRACRANIAL ANEURYSM; JAPAN; KOREA; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DEGRADATION; SINGLE NUCLEOTIDE POLYMORPHISM;

3' UNTRANSLATED REGIONS; ADULT; AGED; ASIAN CONTINENTAL ANCESTRY GROUP; CASE-CONTROL STUDIES; CELLS, CULTURED; CHROMOSOMES, HUMAN, PAIR 7; ELASTIN; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; INTRACRANIAL ANEURYSM; JAPAN; KOREA; MALE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROMOTER REGIONS (GENETICS); PROTEIN KINASES;

EID: 33745205796     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddl096     Document Type: Article

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